...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 8175723 | Steroid eluting pacing tip electrode An implantable cardioverter defibrillator (ICD) including a set of leads having electrodes disposed therein. The electrodes may include a weld electrode connected to an internal wire of the lead and the ICD and a tip electrode. The tip electrode may have a set of gr... | 05/08/2012 |
| 8116883 | Intravascular device for neuromodulation The present disclosure describes intravascular systems that may be used for a variety of functions. The elements of the disclosed systems include at least one device body implanted within the vasculature. Electrodes on a lead and/or on the device body itself are use... | 02/14/2012 |
| 7953499 | Drug-eluting electrode An apparatus includes an electrical lead comprising a lead body and an electrical conductor, and an electrode coupled to the electrical conductor, wherein the electrode includes a coating on at least a portion of a surface of the electrode, the coating including two... | 05/31/2011 |
| 7702399 | Subcutaneous electrode and lead with phoresis based pharmacological agent delivery An implantable subcutaneous device includes a lead and electrode for cardiac monitoring and intervention. The device has an implantable lead including a lead body, a subcutaneous electrode supported by the lead body and a pharmacological agent impelled from the devi... | 04/20/2010 |
| 7657323 | Endovenous device for dispersing a dilating agent Apparatus and methods are disclosed for inserting electrical leads within a heart. A method is provided for positioning a medical electrical lead in a cardiac vein. The method comprises inserting a lead within a coronary sinus, dispersing at least one vasodilating a... | 02/02/2010 |
| 7643885 | Intravenous pacemaker electrode An intravenous pacemaker electrode has an electrode tip designed to release a drug, where the drug contains at least one of the active substances sirolimus, paclitaxel, everolimus, fibrin, rapamycin, and tacrolimus. ... | 01/05/2010 |
| 7584005 | Steroid eluting pacing tip electrode An implantable cardioverter defibrillator (ICD) including a set of leads having electrodes disposed therein. The electrodes may include a weld electrode connected to an internal wire of the lead and the ICD and a tip electrode. The tip electrode may have a set of gr... | 09/01/2009 |
| 7529592 | Subcutaneous electrode and lead with temporary pharmacological agents An implantable subcutaneous device and method employ a lead and an electrode for cardiac monitoring and intervention. The device includes an implantable lead having a lead body, a subcutaneous electrode coupled to the lead body, and a pharmacological agent provided ... | 05/05/2009 |
| 7499757 | Absorbable myocardial lead fixation system A myocardial lead attachment system for securing a distal end of a lead within a myocardium of a patient's heart. The system includes a lead body, an anchor mechanism formed of a bioabsorbable or biodegradable polymer for engaging a surface of the patient's heart an... | 03/03/2009 |
| 7460914 | Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure A method for stimulating angiogenesis is provided that includes the use of an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be electrically connected to the electrical output channel and a distal... | 12/02/2008 |
| 7421295 | Implantable cardiac lead having removable fluid delivery port An implantable cardiac lead includes an elongated lead body having opposed proximal and distal end portions, and a fluid delivery lumen extending therethrough. A connector assembly is operatively associated with the proximal end portion of the lead body. The connect... | 09/02/2008 |
| 7400931 | Devices and methods to stimulate therapeutic angiogenesis for ischemia and heart failure A device that includes an electrical output channel adapted to deliver a sub-threshold voltage, a lead that includes a proximal end adapted to be electrically connected to the electrical output channel and a distal end adapted to be placed in the blood conduit where... | 07/15/2008 |
| 7398126 | Drug dispensing medical electrode lead and method for making same In an electrically conductive lead adapted for implantation in a human or animal body, and a method for making such a lead, a drug-dispensing member is disposed at a distal end portion of the lead, at which an electrode member is disposed that is adapted to emit and... | 07/08/2008 |
| 7386350 | Combination electrical stimulating and infusion medical device A combined electrical and chemical stimulation lead is especially adapted for providing treatment to intervertebral discs. The combination lead may be placed proximate to intervertebral disc cellular matrix and nucleus pulposus tissue to promote tissue regeneration ... | 06/10/2008 |
| 7371258 | Valved prosthesis with porous substrate An implantable prosthesis can be formed from an improved biocompatible material that provides for cellular colonization of the biocompatible material. Specifically, the biocompatible material is a rigid porous material. In embodiments of particular interest, the imp... | 05/13/2008 |
| 7366574 | Device for the transvenous cardioversion of atrial fibrillation or atrial flutter A transvenous catheter for the cardioversion of atrial fibrillation or atrial flutter and/or the stimulation of the heart's activity. The catheter has an electrically active section within a heart and an electrically passive section carrying electrical cables. At le... | 04/29/2008 |
| 7366573 | Polymer lead covering with varied material properties This document discusses, among other things, a lead assembly including a lead body, at least one conductor extending through the lead body, and a covering having varied material properties. In an example, the covering is made by forming pieces of material having var... | 04/29/2008 |
| 7363074 | Coatings comprising self-assembled molecular structures and a method of delivering a drug using the same A coating for an implantable medical device is disclosed, the coating including a self-assembled molecular structure. The coating can be used for altering the release rate of a therapeutic substance from the implantable device. ... | 04/22/2008 |
| 7363091 | Method of molding silicone elastomer drug carrier in an endocardial lead A drug-eluting endocardial lead and method of manufacture. The silicone elastomer of the present invention is ideally suited to a manufacturing environment due to its extended pot life and decreased curing time. A preferred silicone elastomer is comprised of a multi... | 04/22/2008 |
| 7357794 | Devices, systems and methods for acute or chronic delivery of substances or apparatus to extravascular treatment sites Methods and apparatus for delivery of substances or apparatus to target sites located outside blood vessels within the body of a human or animal patient. A vessel wall penetrating catheter is inserted into the vasculature, positioned and oriented within a blood vess... | 04/15/2008 |
| 7353066 | Self-sealing insulation employed on a catheter or lead An implantable electrical medical lead for a pulse generator includes a distal electrode, a connector for electrical connection with the pulse generator, an electrical conductor within the lead extending between the connector and the distal electrode, and an insulat... | 04/01/2008 |
| 7353067 | Implantable leads, electrode portions and methods for securing An exemplary lead and sheath assembly suitable for positioning in the human body includes a lead body, a sheath surrounding the lead body, one or more conductors embedded in the lead body and one or more conduits that allow for a flow of adhesive or an adhesive comp... | 04/01/2008 |
| 7337009 | Lead having composite tubing A lead assembly includes a flexible lead body which extends from a proximal end to a distal end, the lead body includes one or more conductors. The lead assembly further includes an electrode assembly, and at least one coating of insulative material coated directly ... | 02/26/2008 |
| 7337006 | Methods and systems for modulating neural tissue Some embodiments of the present invention provide methods and systems for modulating neural tissue including systems and components for selective stimulation and/or neuromodulation of targeted neural tissue. Targeted neural tissue may include one or more ganglia inc... | 02/26/2008 |
| 7337011 | System and method for enhancing cardiac signal sensing by cardiac pacemakers through genetic treatment The present invention provides delivery systems for and methods of delivering ion channel protein genetic material to cardiac cells in areas adjacent to where an electrode is to be positioned in a patient's heart to improve or correct the signal to noise ratio of ca... | 02/26/2008 |
| 7320675 | Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure A drug delivery system detects a cardiac condition indicative of a need for increasing a cardiac metabolic level and, in response, releases a drug into tissue or blood to shift a source of metabolically synthesized energy fueling cardiac contraction from fatty acid ... | 01/22/2008 |
| 7289856 | Medical electrical lead containing a pyroelectric material A medical electrical lead containing a pyroelectric material is provided. The pyroelectric material is capable of dissipating heat generated in the lead due to radio frequency energy. The pyroelectric material may be a polymeric material, such as polyvinylidene fluo... | 10/30/2007 |
| 7282213 | Method for applying a drug coating to a medical device A method for coating a medical device with a drug is provided. Energy, preferably thermal energy, is applied to a crystalline deposit of a drug on the surface of a medical device to increase the molecular mobility and form a conformable drug coating with a low densi... | 10/16/2007 |
| 7274966 | Medical fluid delivery system A medical fluid delivery system includes an implantable medical lead including a fixation element adapted to secure the lead to a tissue site and a fluid delivery device including a tissue piercing distal tip; the device is adapted to pass through a proximal port, a... | 09/25/2007 |
| 7257449 | Extendable/retractable lead having downsized lead body A lead assembly includes a flexible lead body extending from a proximal end to a distal end, and the lead body includes two or more conductors disposed therein. The second conductor is disposed within the first conductor, and the second conductor has a coating of in... | 08/14/2007 |
| 7251532 | Medical lead fixation A distal tip coupled to a body of an implantable medical device includes a canted passageway extending distally from a lumen of the body and an opening terminating the passageway and positioned in proximity to a distal end of the distal tip; a helical fixation eleme... | 07/31/2007 |
| 7245973 | His bundle mapping, pacing, and injection lead A cardiac rhythm management system includes a lead assembly for intracardiac mapping, pacing, and drug delivery. The lead assembly includes an implantable endocardial lead having a proximal end for connection to an implantable cardiac rhythm management device and a ... | 07/17/2007 |
| 7236821 | Chronically-implanted device for sensing and therapy Systems, devices and methods are provided for providing sensing and therapy functions using a chronically-implanted device. According to one embodiment, the device includes a structure adapted to be chronically placed within a biosystem, and further includes sensing... | 06/26/2007 |
| 7236834 | Electrical lead body including an in-line hermetic electronic package and implantable medical device using the same An assembly is provided for an implantable medical lead. The assembly includes a first lead body comprising one or more electrical leads, and a hermetic encasement. The encasement comprises a housing having first and second openings and interior walls, an interior s... | 06/26/2007 |
| 7225024 | Sensors having protective eluting coating and method therefor A cardiac management implantable device that has an intravascular device body, and one or more chemical sensors coupled with the intravascular device body. A drug eluting substance is disposed at a location including at least one of on, directly adjacent, or near th... | 05/29/2007 |
| 7218971 | Implantable lead with dissolvable coating for improved fixation and extraction A cardiac rhythm management system provides an endocardial cardiac rhythm management lead with an at least partially dissolvable coating at least partially on insulating portions of the lead body at or near its distal end. Upon dissolution, the coating promotes tiss... | 05/15/2007 |
| 7211063 | Pressure sensor for therapeutic delivery device and method The present invention is an apparatus for treating a selected patient tissue or organ region, at the surface of such region. The apparatus has an accessing tool for accessing the patient region, the tool having a distal end, and a proximal end at which the tool can ... | 05/01/2007 |
| 7209792 | RF-energy modulation system through dynamic coil detuning An RF-energy modulation system dynamically adjusts tuned receiving circuits within a plurality of slave devices, thereby regulating the level of power reception in each slave device. The slave devices receive power from a single master device, through coupling of a ... | 04/24/2007 |
| 7209783 | Ablation stent for treating atrial fibrillation An apparatus and method for treating atrial fibrillation with ablation therapy in which a stent is deployed within a pulmonary vein and tissue surrounding the stent is ablated with radiofrequency energy to stop discharges from ectopic foci in the vein from reaching ... | 04/24/2007 |
| 7203550 | Implantable medical device with a current generated for infection control In a cardiac stimulating device, an infection control current is generated and applied to a subject in whom a medical device is implanted by completing a circuit including an entirely electrically conductive exterior of a housing of the device, an electrode carried ... | 04/10/2007 |