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| Number | Title | Issue Date |
| 8092490 | Photochemical tissue bonding Photochemical tissue bonding methods include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tis... | 01/10/2012 |
| 7842070 | Vascular sealant delivery device and sheath introducer and method A sheath introducer is inserted through the skin and into a body lumen, e.g., the femoral artery, for a medical procedure. Upon completion of the medical procedure, the sheath introducer is partially withdrawn from the body lumen so that at least one through-wall ho... | 11/30/2010 |
| 7766938 | Pleural effusion treatment device, method and material The invention discloses a method of treating a patient for pleural effusion comprising percutaneously delivering an adhesive material to a pleural space of the patient. Suitable adhesive materials for performing any of the embodiments of the methods of the invention... | 08/03/2010 |
| 7553319 | Auto-injector apparatus and methods for sealing a vascular puncture Apparatus for sealing a puncture communicating with a blood vessel includes a pair of syringe barrels having sealing components therein, and a plunger assembly biased to slide within the barrels from proximal to distal positions for injecting the components through ... | 06/30/2009 |
| 7431729 | Patent foramen ovale (PFO) closure device with radial and circumferential support The present invention provides a device for occluding an anatomical aperture, such as a septal defect or patent foramen ovale (PFO). The occluder includes two sides connected by an intermediate joint. Each of the sides includes at least one elongate element, which i... | 10/07/2008 |
| 7371403 | Wound dressing and method for controlling severe, life-threatening bleeding This invention is directed to advanced hemorrhage control wound dressings, and methods of using and producing same. The subject wound dressing is constructed from a non-mammalian material for control of severe bleeding. The wound dressing for controlling severe blee... | 05/13/2008 |
| 7351249 | Systems, methods, and compositions for achieving closure of suture sites Systems and methods employ functional instruments to close incisions and wounds using a suture knot in combination with a biocompatible material composition. The systems and methods are well suited for use, for example, at a vascular puncture site following a vascul... | 04/01/2008 |
| 7351426 | Polyester/cyanoacrylate tissue adhesive compositions This invention addresses absorbable cyanoacrylate-based tissue adhesive compositions based primarily on an alkoxy cyanoacrylate combined with one or more alkyl cyanoacrylate(s), a stabilizer against premature anionic polymerization, and/or an absorbable polymeric mo... | 04/01/2008 |
| 7347850 | Adhesion barriers applicable by minimally invasive surgery and methods of use thereof Biocompatible crosslinked polymers, and methods for their preparation and use with minimally invasive surgery applicators are disclosed. The disclosure includes compositions and methods for in situ formation of hydrogels using minimally invasive surgical techniques.... | 03/25/2008 |
| 7338506 | Scleral clip and procedures for using same A method and clip for treating presbyopia and/or open angle glaucoma in which the sclera is supported or reinforced, while substantially maintaining the special relationship between the ciliary muscle and the lens. The method includes making an incision in the conju... | 03/04/2008 |
| 7318933 | Systems, methods, and compositions for achieving closure of vascular puncture sites Systems, methods, and compositions achieve rapid closure of vascular puncture sites. The systems and methods form a vascular closure composition by mixing together a first component, a second component, and a buffer material. The first component includes an electrop... | 01/15/2008 |
| 7316705 | Adhesive including medicament and device and method for applying same The present invention provides a device and method for safely applying cyanoacrylate or other adhesives to skin lacerations. ... | 01/08/2008 |
| 7303757 | Biocompatible phase invertable proteinaceous compositions and methods for making and using the same Biocompatible phase invertable proteinaceous compositions and methods for making and using the same are provided. The subject phase invertable compositions are prepared by combining a proteinaceous substrate and a cross-linker. The proteinaceous substrate includes o... | 12/04/2007 |
| 7285097 | Technique to confirm correct positioning with respect to arterial wall Methods and systems related to sealing punctures in blood vessels (such as following an angio or PTCA procedure) are disclosed. The invention provides a system to sense the location of a distal portion of a member within a body. The system includes an introducer por... | 10/23/2007 |
| 7279001 | Systems, methods, and compositions for achieving closure of vascular puncture sites Systems and methods convey a closure material into a catheter, e.g., to seal a puncture site in a blood vessel. The closure material comprises a mixture of first and second components, which, upon mixing, undergo a reaction to form solid closure material composition... | 10/09/2007 |
| 7267681 | Wound closure system and method Methods and systems for closing wounds using wound closures and a flowable adhesive skin paint are disclosed. The flowable adhesive does not adhere the wound closures to the skin over the wound to reduce irritation. In some embodiments, the skin paint may include 1-... | 09/11/2007 |
| 7247314 | Biocompatible material composition adaptable to diverse therapeutic indications A biocompatible material genus serves as the foundation for multiple material composition species, each adapted to a specific therapeutic indication. ... | 07/24/2007 |
| 7241736 | Compositions and methods for treating diverticular disease Agents, compositions, and implants are provided herein for treating diverticular disease (e.g., diverticulosis and diverticulitis). In particular, fibrosis-inducing agents, hemostatic agents, and/or anti-infective agents, or compositions containing one or more of th... | 07/10/2007 |
| 7241316 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be â... | 07/10/2007 |
| 7235107 | Devices and methods for treating defects in the tissue of a living being An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or additives, where the implant may also be used for therapy delivery. A... | 06/26/2007 |
| 7226615 | Expandable foam-like biomaterials and methods Liquid, injectable, aqueous solutions are transformed in situ to an expandable foam-like, space filling, and adherent biomaterial. Preferably, the foam-like biomaterial is the reaction product of a two-part liquid system to achieve the in situ formation thereof. The... | 06/05/2007 |
| 7217254 | Multi-pressure biocompatible agent delivery device and method A device for application of material to a surface, for example, biocompatible material to a tissue surface in a medical or clinical setting, is adapted to receive one or more biocompatible materials and one or more sources of pressurized medical gas, and to deliver ... | 05/15/2007 |
| 7211651 | Proteinaceous gels having visualization agents and methods of use thereof Proteinaceous gels having visualization agents and methods of use thereof are disclosed herein. Further, polymeric crosslinking agents are disclosed that have an inert water soluble polymeric component, biodegradable components, functional components reactive with c... | 05/01/2007 |
| 7207535 | Mounting device A device for mounting taxidermy mounts, especially waterfowl and other birds. The mounting device prevents the mounted object from twisting or slipping on the mount and the mounted object can be prevented from sagging. The mounting device allows for the mounting of ... | 04/24/2007 |
| 7186249 | Thermally conductive surgical probe A surgical apparatus and process for freezing or cauterizing a particular infected body area employing a transparent sleeve insertable through a small slit in the flesh of a patient and wherein the inserted end of the sleeve is provided with a cone-shaped tip having... | 03/06/2007 |
| 7182744 | Method and apparatus for aneurismal treatment An irritant or polymer is dispensed to the inner surface area of an aneurysm to exert a contractile force on the inner surface area of the aneurysm, thereby shrinking the aneurysm. As a result, the artery wall at the aneurysm site is strengthened, the risk of ruptur... | 02/27/2007 |
| 7166133 | Devices and methods for treating defects in the tissue of a living being An implant for deployment in select locations or select tissue for regeneration of tissue is disclosed. The implant comprising collagen and or other bio-resorbable materials, where the implant may also be used for therapy delivery. Additionally, the implant may be â... | 01/23/2007 |
| 7166570 | Medical implants and fibrosis-inducing agents Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue. ... | 01/23/2007 |
| 7163997 | Polyether derivative and process for producing the same The present invention relates to a polyether derivative represented by the following general formula (I): wherein X1 represents —CO— or —SO2—; Ar1 | 01/16/2007 |
| 7156880 | Devices and methods for treating defects in the tissue of a living being An implantable material for deployment in select locations or select tissue for tissue regeneration is disclosed. The implant comprises collagen, ceramics, and or other bio-resorbable materials or additives, where the implant may also be used for therapy delivery. A... | 01/02/2007 |
| 7151895 | Method and system for automatically setting gain for an amplifier in an optical network A method for automatically setting a gain for an amplifier in an optical network includes transmitting, from a source proximate an upstream amplifier coupled to an optical span, a stable signal over the optical span. The method also includes using the stable signal ... | 12/19/2006 |
| 7138441 | Bioabsorbable blends and surgical articles therefrom Blends made of bioabsorbable materials including glycolide, lactide, caprolactone, dioxanone, trimethylene carbonate, alkylene glycols, esteramides, etc., and polymers and copolymers thereof with cyanoacrylates are described. Processes for making the polymers and su... | 11/21/2006 |
| 7129210 | Tissue adhesive sealant A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited... | 10/31/2006 |
| 7125837 | Elastin-based compositions The present invention provides screening methods that use organisms or cells that lack function in one or both elastin genes. These methods are useful in identifying drugs for the prevention and treatment of obstructive vascular diseases, such as atherosclerosis, va... | 10/24/2006 |
| 7115127 | Methods and apparatus for hemostasis following arterial catheterization A method for accelerating hemostasis of an artery having a puncture after arterial catheterization, the catheterization using a catheter introducer, the method including the steps of inserting into an artery a catheter introducer prior to arterial catheterization, f... | 10/03/2006 |
| 7112210 | Surgical instrument and method for treating female urinary incontinence The invention relates to a surgical instrument and a method for treating female urinary incontinence. A tape or mesh is permanently implanted into the body as a support for the urethra. In one embodiment, portions of the tape comprise tissue growth factors and adhes... | 09/26/2006 |
| 7105011 | Method for achieving tissue changes in bone or bone-derived tissue A method of achieving tissue changes in bone or bone-derived organic tissue, in which method bone or bone-derived organic tissue is provided, an interfacing agent is applied to the bone or bone-derived organic tissue, and electromagnetic energy is applied to the int... | 09/12/2006 |
| 7094369 | Processes for manufacturing polymeric microspheres Processes of manufacturing polymeric microspheres facilitate the generation of polymeric microspheres of size ranges smaller than 600 microns diameter by forming beads of a predetermined size from a starting material which may include a template polymer, and subsequ... | 08/22/2006 |
| 7083634 | Stabilized polyester/cyanoacrylate tissue adhesive formulation The present invention is directed to adhesive/hemostatic formulations of 2-alkoxyalkyl cyanoacrylate, an absorbable liquid or solid polymeric modifier, and a general stabilizer against premature anionic polymerization of cyanoacrylates. The present adhesive formulat... | 08/01/2006 |
| 7081103 | Direct dual filling device for sealing agents A filling device for connecting a dispensing instrument having multiple fluid reservoirs to multiple containers is disclosed. More particularly, the present invention discloses a connecting device capable of coupling the individual reservoirs of a dispensing instrum... | 07/25/2006 |
