Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 8175690 | Optical device for assessing optical depth in a sample An optical device for assessing optical depth in a sample illuminated by polarized radiation from a source include two radiation guides having their end portions arranged for capturing reflected radiation from the sample. A detector measures two polarizations of the... | 05/08/2012 |
| 8140148 | Readable probe array for in vivo use A disposable high-density, optically readable polydeoxynucleotide array with integral fluorescence excitation and fluorescence emission channels is described. The compact array size allows integration into several types of interventional devices such as catheters, g... | 03/20/2012 |
| 8135454 | Diagnosing and performing interventional procedures on tissue in vivo A catheter for diagnosing and performing an interventional procedure on tissue has an elongated catheter shaft, and optical fibers, extending through the catheter shaft, for transmitting light to tissue located at a distal end of the catheter and conveying light bac... | 03/13/2012 |
| 8131350 | Stabilization of visualization catheters Systems for the stabilization of visualization catheters are described herein which facilitate the deployment and retraction of an imaging hood from a catheter. Such systems may include a deployment catheter and an imaging hood having one or more structural elements... | 03/06/2012 |
| 8068899 | Method and system of using intrinsic-based photosensing with high-speed line scanning for characterization of biological thick tissue including muscle Biological thick tissue such as skeletal and cardiac muscle is imaged by inserting a probe into the tissue and scanning the tissue at a sufficiently fast rate to mitigate motion artifacts due to physiological motion. According to one example embodiment, such a probe... | 11/29/2011 |
| 8068898 | Fluorescence lifetime spectrometer (FLS) and methods of detecting diseased tissues This invention relates to method and apparatus for collection of the complete fluorescence emission spectrum and the transient decay of a selected spectral band simultaneously with data acquisition times of less that one second. This invention is useful for studying... | 11/29/2011 |
| 8046057 | Tissue structure identification in advance of instrument A method and apparatus for identifying tissue structures in advance of a mechanical medical instrument during a medical procedure. A mechanical tissue penetrating medical instrument (22) has a distal end for penetrating tissue in a penetrating direction. An o... | 10/25/2011 |
| 8019405 | Device for the picture-providing diagnosis of tissue using one of at least two diagnosis modes A device for picture-providing diagnosis of tissue is selectively operated in a picture-providing white light diagnosis mode and a picture providing auto-fluorescence mode. A color camera having red, green, and blue sensors provides a monitor which picture signals. ... | 09/13/2011 |
| 7970458 | Integrated disease diagnosis and treatment system Designs, implementations, and techniques for optically measuring a sample and integrated systems that provide CT-scan, optical probing and therapy by electromagnetic radiation treatment (e.g. laser, RF, or microwave). Light at different wavelength bands may be used ... | 06/28/2011 |
| 7853316 | Rotating optical catheter tip for optical coherence tomography The present invention relates to a rotating catheter tip for optical coherence tomography based on the use of an optical fiber that does not rotate, that is enclosed in a catheter, which has a tip rotates under the influence of a fluid drive system to redirect light... | 12/14/2010 |
| 7844321 | Rotating catheter probe using a light-drive apparatus The invention is a rotating tip catheter-imaging probe where electromagnetic energy is delivered to the distal end of a catheter and converted to mechanical energy using a light drive apparatus. The mechanical energy is then used to rotate a mirror that redirects li... | 11/30/2010 |
| 7783338 | Catheter with optical fiber sensor An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a thera... | 08/24/2010 |
| 7774048 | Fluorescent endoscope device An endoscope device includes a light source unit that creates multiple excitation lights having different peak wavelengths, an illumination unit, and an imaging unit that includes an objective optical system and an image pickup device. The imaging unit is capable of... | 08/10/2010 |
| 7742805 | Optical catheter with dual-stage beam redirector A catheter includes separate first and second optical channels extending between proximal and distal portion thereof. First and second beam redirectors in optical communication with the respective first and second optical channels each have on-axis stage and an off-... | 06/22/2010 |
| 7711413 | Catheter imaging probe and method A catheter imaging probe for a patient. The probe includes a conduit through which energy is transmitted. The probe includes a first portion through which the conduit extends. The probe includes a second portion which rotates relative to the conduit to redirect the ... | 05/04/2010 |
| 7702381 | Optical fiber delivery and collection method for biological applications such as multiphoton microscopy, spectroscopy, and endoscopy The present invention is directed to a method of applying radiation through an optical fiber for detecting disease within a plant or animal or other penetrable tissue, or imaging a particular tissue of a plant or animal. In addition, fluorescence and nonlinear scatt... | 04/20/2010 |
| 7647092 | Systems and methods for spectroscopy of biological tissue The system and method of the present invention relates to using spectroscopy, for example, Raman spectroscopic methods for diagnosis of tissue conditions such as vascular disease or cancer. In accordance with a preferred embodiment of the present invention, a system... | 01/12/2010 |
| 7529577 | Method and apparatus for locating foreign objects in the ear canal The invention concerns a method for locating foreign objects on the internal surface of ear and ear canal whereby a probe having a light emitting distal portion is inserted into the ear canal, the method further comprising the steps of:—directing light from the di... | 05/05/2009 |
| 7447539 | Method and equipment for fiber optic high-resolution, in particular confocal, fluorescence imaging A method using an image guide having several thousands of optical fibers, an excitation signal emitted by a source, deflected and injected by turns into the optical fibers, each excitation point of the tissue in the fiber output emitting in return a fluorescence sig... | 11/04/2008 |
| 7426410 | Spectroscopy of deeply-scattered light A spectroscope includes first and second beam redirectors in optical communication with first and second fibers respectively. The first and second beam redirectors are oriented to illuminate respective first and second areas. The second area is separated from the fi... | 09/16/2008 |
| 7368716 | Infrared imaging system and lens module for use with the same An IR imaging system includes a lens module and an imaging module coupled to the lens module. The lens module includes a barrel defining a through hole, at least one lens received in the through hole and an IR bandpass filter received in the barrel and configured fo... | 05/06/2008 |
| 7364543 | Paired angled rotation scanning probes and methods of use Probes, and systems and methods for optically scanning a conical volume in front of a probe, for use with an imaging modality, such as Optical Coherence Tomography (OCT). A probe includes an optical fiber having a proximal end and a distal end and defining an axis, ... | 04/29/2008 |
| 7366365 | Tissue scanning apparatus and method A system for multispectral confocal mapping of a tissue, comprising: a light source; an optical fiber having an aperture providing a confocal pinhole, a scanner being free-space coupled to said aperture and operative to scan the tissue and provide intensity signals ... | 04/29/2008 |
| 7364562 | Anti-clotting apparatus and methods for fluid handling system A method for maintaining clear passageways in an extracorporeal blood flow system. The method comprises intermittently providing one or more anti-clotting agents to a passageway of the extracorporeal blood flow system. Also disclosed is an extracorporeal blood flow ... | 04/29/2008 |
| 7365842 | Light scanning type confocal microscope A light scanning type confocal microscope includes a light source unit that projects an excitation light beam, a scanning optical system that scans the excitation light beam, an objective lens that applies the excitation light beam to a sample, a separation optical ... | 04/29/2008 |
| 7353055 | Non-invasive analysis system A non-invasive analysis system suitable for measuring blood glucose concentration includes a broadband set of coherent beams, with relatively low divergence angle, optical source. It further includes an optical processing system which provides a probe and a referenc... | 04/01/2008 |
| 7348528 | Distance measuring system A distance measuring device capable of being used in microscopes or other optical systems. Embodiments of the invention employ one or more scanning mirrors to scan a reference beam over a target to be inspected. The reference beam is returned and detected by a photo... | 03/25/2008 |
| 7349130 | Automated scanning system and method A system and method for mass, automated scanning of objects, including dental study casts, housing parts, and other objects. The system and method are able to function with little or no human operator intervention, thereby facilitating high volume scanning and reduc... | 03/25/2008 |
| 7341557 | Compact fluorescence endoscopy video system A fluorescence endoscopy video system includes a multimode light source that produces light for color and fluorescence imaging modes. Light from the light source is transmitted through an endoscope to the tissue under observation. The system also includes a compact ... | 03/11/2008 |
| 7339341 | Surgical camera robot The present invention is a miniature camera robot which can be placed entirely within an open space such as an abdominal cavity. The instant camera robot has pan and tilt capabilities, an adjustable focus camera, and a support component for supporting the robot body... | 03/04/2008 |
| 7337066 | System and method for automated baseline correction for Raman spectra A system and method for automated baseline correction for Raman spectra is disclosed which may operate as a piecewise-linear baseline correction function. In an embodiment, a first set of data points from a Raman spectrum are determined to be baseline data points, a... | 02/26/2008 |
| 7336988 | Multi-photon endoscopy An apparatus includes an optical element, a GRIN lens, and a detector. The optical element has a first optical aperture. The GRIN lens has first and second ends. The first end of the GRIN lens is positioned to receive light from the first optical aperture. The detec... | 02/26/2008 |
| 7330270 | Method to suppress artifacts in frequency-domain optical coherence tomography One embodiment of the present invention is a method for suppressing artifacts in frequency-domain OCT images, which method includes (a) providing sample and reference paths with a significant difference in their chromatic dispersion (b) correcting for the effects of... | 02/12/2008 |
| 7329223 | Catheter with optical fiber sensor An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a thera... | 02/12/2008 |
| 7330749 | Fluorescence electronic endoscopic system In fluorescent endoscopic examinations, excitation light and light adjusted by an adjuster filter are alternately projected to an object under observation, the fluorescence light is received by one channel out of three channels by disposing barrier filters before a ... | 02/12/2008 |
| 7319782 | Real-time imaging and analysis system A sub-surface imaging system includes a broadband set of coherent beams with low divergence angle. It further includes an optical processing system which provides a probe and a reference beam, applies the probe beam to the target to be analyzed, recombines the beams... | 01/15/2008 |
| 7313432 | Phase discrimination for detection of vulnerable-plaque A system for identifying vulnerable plaque includes an illumination subsystem for passing an illumination beam, modulated by a first modulation waveform, through a catheter. A receiving subsystem detects a collection beam, which is modulated by a second modulated wa... | 12/25/2007 |
| 7309867 | Methods and apparatus for characterization of tissue samples The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade 1), CIN 2/3 (cervical intraepithelial neoplasia grades 2 and/or 3), no... | 12/18/2007 |
| 7310547 | Fluorescent fiberoptic probe for tissue health discrimination A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at... | 12/18/2007 |
| 7309316 | Magnetic needle biopsy An apparatus and method for performing biopsies in-vivo using magnetically labeled nanoparticles is disclosed. One embodiment of the apparatus is called a magnetic needle. When used in a biopsy, one embodiment of the present invention collects cancer cells in-vivo w... | 12/18/2007 |
