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| Number | Title | Issue Date |
| 8150501 | Method for measuring skin erythema A method for measuring skin erythema and determining the efficacy of skin care treatment products utilizing digital images. ... | 04/03/2012 |
| 8131349 | Lesion extracting device and lesion extracting method A lesion extracting device having a control unit for changing an amount of the excitation light emitted toward a subject body, a measuring unit for measuring a change in the intensity of fluorescence generated from the subject body with respect to a change in the am... | 03/06/2012 |
| 7835786 | Methods, systems, and computer program products for optimization of probes for spectroscopic measurement in turbid media Methods, systems, and computer program products for optimizing a probe geometry for spectroscopic measurement in a turbid medium are provided. A probe geometry comprising one emitting entity and at least on collecting entity is selected. A simulation is performed to... | 11/16/2010 |
| 7826890 | Optical detection of intravenous infiltration An intravenous infiltration detection apparatus for monitoring intravenous failures, which applies an optical method coupled with fiber optics and algorithms for tissue optics to provide a means for noninvasive detection of intravenous infiltration surround the site... | 11/02/2010 |
| 7738946 | System, method and apparatus for the detection of patient-borne fluorescing materials System, method and apparatus wherein a probe employing non-imagining optics is utilized in conjunction with a fluorescing (e.g., nanocrystal) tracer at the body of a patient. Excitation components within the probe working end are utilized to excite the nanocrystals ... | 06/15/2010 |
| 7729751 | Electronic endoscopic apparatus A spectral image obtainment unit obtains spectral image data by receiving reflection light in different wavelength bands, into which light reflected by a living body mucous membrane has been separated, at a light receiving unit by causing a ratio of a light receivin... | 06/01/2010 |
| 7689269 | System, method and apparatus for the detection of patient-borne fluorescing nanocrystals System, method and apparatus wherein a probe employing non-imagining optics is utilized in conjunction with a fluorescing nanocrystal tracer at the body of a patient. Excitation components within the probe working end are utilized to excite the nanocrystals to fluor... | 03/30/2010 |
| 7623908 | Nonlinear interferometric vibrational imaging A method of examining a sample, which includes: exposing a reference to a first set of electromagnetic radiation, to form a second set of electromagnetic radiation scattered from the reference; exposing a sample to a third set of electromagnetic radiation to form a ... | 11/24/2009 |
| 7587236 | Optical spectroscopy for the detection of ischemic tissue injury An optical method and apparatus is utilized to quantify ischemic tissue and/or organ injury. Such a method and apparatus is non-invasive, non-traumatic, portable, and can make measurements in a matter of seconds. Moreover, such a method and apparatus can be realized... | 09/08/2009 |
| 7426410 | Spectroscopy of deeply-scattered light A spectroscope includes first and second beam redirectors in optical communication with first and second fibers respectively. The first and second beam redirectors are oriented to illuminate respective first and second areas. The second area is separated from the fi... | 09/16/2008 |
| 7365839 | Process and compositions for synthetic calibration of bio-photonic scanners A method, apparatus, and set of compositions are disclosed for calibrating a bio-photonic scanner. The scanner detects selected molecular structures of tissues, nondestructively, in vivo. The apparatus may include a computer, including processor and memory connectin... | 04/29/2008 |
| 7365844 | Vision enhancement system for improved detection of epithelial neoplasia and other conditions Systems and methods for diagnosing epithelial neoplasia and other conditions includes, in a representative embodiment, providing the human eyes with a filter to observe the autofluorescence of a tissue sample. Using optimized wavelengths from a filtered light source... | 04/29/2008 |
| 7359748 | Apparatus for total immersion photography Total Immersion Photography (TIP) is disclosed, preferably for the use of screening for various medical and cosmetic conditions. TIP, in a preferred embodiment, comprises an enclosed structure that may be sized in accordance with an entire person, or individual body... | 04/15/2008 |
| 7351362 | Photochromic material A photochromic material comprising a styrene-based oligomer having a weight average molecular weight of from 200 to 6000 and a photochromic compound selected from the group consisting of spirooxazine derivatives and spiropyran derivatives. ... | 04/01/2008 |
| 7336989 | System and method for quantitative or qualitative measurement of exogenous substances in tissue and other materials using laser-induced fluorescence spectroscopy Methods and systems for determination of one or more substances within a material are described. A flow of fluorescence-exciting/ablative energy (e.g., laser pulse(s), preferably in the ultraviolet region (e.g. 193-nm)), is directed onto the material to ablate a thi... | 02/26/2008 |
| 7336990 | Equipment for subsurface autofluorescence spectroscopy An equipment includes an excitation source (1), elements for injecting (2) an excitation signal produced by the source in an ordered bundle (3) of flexible optical fibers, elements for analyzing (21, 22) an emitted autofluorescence signal... | 02/26/2008 |
| 7329223 | Catheter with optical fiber sensor An apparatus and method to perform therapeutic treatment and diagnosis of a patient's vasculature through the use of an intravascular device having an optical fiber disposed therein. In an embodiment, the apparatus includes an intravascular device to perform a thera... | 02/12/2008 |
| 7328059 | Imaging of light scattering tissues with fluorescent contrast agents A system and method for non-invasive biomedical optical imaging and spectroscopy with low-level light is described. The technique includes a modulated light source coupled to tissue to introduce excitation light. Fluorescent light emitted in response to the excitati... | 02/05/2008 |
| 7328060 | Cancer detection and adaptive dose optimization treatment system The present invention utilizes a series of optical and electronic elements to detect and image cancerous and/or pre-cancerous cells in living tissue. The invention further uses the images thus obtained to adaptively and dynamically shape a treatment light beam so as... | 02/05/2008 |
| 7324661 | Computer-implemented system and method for automated and highly accurate plaque analysis, reporting, and visualization A computer-implemented system and method of intra-oral analysis for measuring plaque removal is disclosed. The system includes hardware for real-time image acquisition and software to store the acquired images on a patient-by-patient basis. The system implements alg... | 01/29/2008 |
| 7313432 | Phase discrimination for detection of vulnerable-plaque A system for identifying vulnerable plaque includes an illumination subsystem for passing an illumination beam, modulated by a first modulation waveform, through a catheter. A receiving subsystem detects a collection beam, which is modulated by a second modulated wa... | 12/25/2007 |
| 7309867 | Methods and apparatus for characterization of tissue samples The invention provides methods for determining the probability that a given region of a tissue sample contains tissue of a given category, such as CIN 1 (cervical intraepithelial neoplasia, grade 1), CIN 2/3 (cervical intraepithelial neoplasia grades 2 and/or 3), no... | 12/18/2007 |
| 7310547 | Fluorescent fiberoptic probe for tissue health discrimination A system and method for the in situ discrimination of healthy and diseased tissue. A fiberoptic based probe is employed to direct ultraviolet illumination onto a tissue specimen and to collect the fluorescent response radiation. The response radiation is observed at... | 12/18/2007 |
| 7304724 | Method and apparatus for quantification of optical properties of superficial volumes A device and method for accurately performing quantitative diffuse optical spectroscopy on a sample includes a light source and a source optical fiber that is optically coupled to the light source. A diffuser material is interposed between the source optical fiber a... | 12/04/2007 |
| 7304741 | Pesticide detector and method Highly portable, handheld instrument which can be pointed at the produce to be checked. Light from a source within the instrument is directed onto the produce to induce fluorescent emission from the produce, and fluorescent emissions from the produce are monitored w... | 12/04/2007 |
| 7301629 | Apparatus and method for determining tissue characteristics An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detec... | 11/27/2007 |
| 7302287 | Methods of detecting inflammation of an epithelium layer in the oral region with a probe using diffuse-reflectance spectroscopy The invention provides a device and method for monitoring inflammation of the epithelium. The device consists of a head region, a handle region and an optical bundle. At least two of the optical fibers in the bundle are utilized as a source of radiation, these two f... | 11/27/2007 |
| 7286870 | Optical system for measuring metabolism in a body and imaging method In an optical measurement system and imaging method adapted to measure in vivo information in a living body without harming the living body, light rays of a plurality of wavelengths which are modulated in intensity with a plurality of different frequencies are irrad... | 10/23/2007 |
| 7282723 | Methods and apparatus for processing spectral data for use in tissue characterization The invention provides methods for processing tissue-derived spectral data for use in a tissue classification algorithm. Methods of the invention comprise application of spectral and/or image masks for automatically separating ambiguous or unclassifiable spectral da... | 10/16/2007 |
| 7280866 | Non-invasive screening of skin diseases by visible/near-infrared spectroscopy A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible/near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spec... | 10/09/2007 |
| 7264616 | Method of utilizing a surgical drain with sensors for monitoring internal tissue condition The present invention is directed to devices and methods of using a surgical drain, and more particularly to a surgical drain having at least one sensor for monitoring and/or recording the condition of the anatomical site or fluid emitted from the site where the sur... | 09/04/2007 |
| 7260248 | Image processing using measures of similarity The invention provides methods of relating a plurality of images based on measures of similarity. The methods of the invention are useful in the segmentation of a sequence of colposcopic images of tissue, for example. The methods may be applied in the determination ... | 08/21/2007 |
| 7253894 | Image detection apparatus for fluorescence and reflectance imaging and spectroscopy and for contemporaneous measurements of electromagnetic radiation with multiple measuring devices Optical systems that provide for simultaneous images and spectra from an object, such as a tissue sample, an industrial object such as a computer chip, or any other object that can be viewed with an optical system such as a microscope, endoscope, telescope or camera... | 08/07/2007 |
| 7248356 | Calibration aid A calibration aid may be assembled as follows. First, the standard reference substance is prepared by dissolving ICG dye and albumin protein in water. Then, the carrier sheet of fleece material is soaked therein and dried. After drying the carrier sheet, a thin well... | 07/24/2007 |
| 7242832 | Device for tissue characterization A probe for use in characterizing tissue. The probe includes a plurality of optical fibers and an optical element. Each fiber includes a distal portion and a proximal portion. The fibers transmit light through the fiber to a surrounding area and collect light reflec... | 07/10/2007 |
| 7236815 | Method for probabilistically classifying tissue in vitro and in vivo using fluorescence spectroscopy Fluorescence spectral data acquired from tissues in vivo or in vitro is processed in accordance with a multivariate statistical method to achieve the ability to probabilistically classify tissue in a diagnostically useful manner, such as by histopathological classif... | 06/26/2007 |
| 7235045 | Fluorescence imaging endoscope An endoscope having an optical guide that is optically coupled to a first broadband light source and a second laser light source that emits light at a wavelength in a range of 350 nm to 420 nm. The endoscope has an image sensor at a distal end and collects a reflect... | 06/26/2007 |
| 7231243 | Optical methods for tissue analysis The invention relates to methods and systems to optically analyze samples such as tissue based on speckle patterns of microscopic motion, such as Brownian motion. ... | 06/12/2007 |
| 7215420 | Optical method and apparatus for determining status of agricultural products A spectroscopic method, preferably Raman scattering, is used to rapidly determine the general health or stress status of living plants and plant products, including agricultural crops, forests, and harvested fruits and vegetables. In the preferred embodiments, carot... | 05/08/2007 |
| 7201767 | Device for ultraviolet radiation treatment of body tissues The device for ultraviolet radiation treatment of body tissues includes a UV light source, a halogen light source and a viewing mechanism all connected to a trifurcation joint by fiber optic cables. All three fiber optics cables are bundled together and exit the tri... | 04/10/2007 |
