William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Number | Title | Issue Date |
| 7384794 | Micro-devices and analytical procedures for investigation of biological systems Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the investigation of living systems. A number of interfaces to analytical instru... | 06/10/2008 |
| 7356366 | Device for monitoring fluid status A technique for determining a patient's hematocrit by an electrical impedance measurement is described. An implantable device may be configured to utilize the technique in order to assess a cardiac patient's fluid status. In order to determine the hematocrit, the el... | 04/08/2008 |
| 7250775 | Microfluidic devices and methods based on measurements of electrical admittance Microfluidic devices and methods that use electrical admittance as the basis for measuring flow rate of fluids and/or for distinguishing (e.g., characterizing, sorting, separation, etc.) different particles, chemical compositions or biospecies (e.g., different cells... | 07/31/2007 |
| 6058934 | Planar hematocrit sensor incorporating a seven-electrode conductivity measurement cell A conductivity sensor for measuring hematocrit and a sensor housing for a blood analysis instrument using the conductivity sensor are described. The conductivity sensor includes a seven-electrode conductivity measurement cell in which three symmetric pair... | 05/09/2000 |
| 5728281 | Implantable medical device including an arrangement for measuring a blood property having a carbon reference electrode An implantable medical device for in vivo electrochemical measurements of blood properties, such as measurements of, inter alia, oxygen pressure, glucose and pH, avoids the problem with the reference electrodes currently in use which cause inflammatory re... | 03/17/1998 |
| 5325853 | Calibration medium containment system A method and apparatus which contemplates coverage control, and collateral containment of calibration media with respect to diverse electrodes in a flow-through calibration and measurement cell during storage and sensor calibration and in which the calibr... | 07/05/1994 |
| 4553552 | Hemodialysis meter A hemodialysis conductivity meter apparatus is provided for measuring dialysate concentration using a self contained syringe. The meter includes a syringe body having a needle attached thereto with a syringe plunger coacting with the body to draw fluid in... | 11/19/1985 |
| 4542751 | Sweat-collecting device and method A sweat-collection device formed as a solid body having a shallowly concave, sweat-collecting surface at a face thereof defining a concavity with a rim lying wholly within a common plane for firm placement over an iontophoresis-stimulated area of a person... | 09/24/1985 |
| 4535786 | Measurement of body fluid chemistry A method and apparatus are disclosed in which body fluid chemistry is measured in either differential or nondifferential mode using apparatus of the kind employed in infusing fluids into patients' blood streams, either with or without combination with suc... | 08/20/1985 |
| 4484582 | Electrolytic fluid flow rate method and apparatus A system for measuring the flow rate of electrolytic fluids includes a flow cell which has a cylindrical flow channel receptive of the fluid flow to be measured and a pair of spaced apart electrodes configured to conform to the cylindrical surface of the ... | 11/27/1984 |
| 4266556 | Electrically heated sweat collection device and method A sweat collection device for use with equipment for inducing human sweat has an electrically heated cup member whose temperature is maintained substantially constant by monitoring the temperature of the cup and controlling the electrical power supplied t... | 05/12/1981 |