Glam girl Heddy Lamar may have used her good looks to good effect on the silver screen, but she put her smarts to better use as an inventor. During World War II, she co-patented a frequency-switching system for torpedo guidance that was considered years ahead of its time.
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| Number | Title | Issue Date |
| 8039680 | Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol A process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol including the following steps: (A): a step for fluorinating 2,3,5,6-tetrachloroterephthaloyl dichloride, (B): a step for reducing the product obtained in step (A), (C): a step for chlorinating the pr... | 10/18/2011 |
| 7414078 | Oral general anesthetics and metabolitically resistant anticonvulsants The present invention is directed to novel themisone derivative compounds that have been modified to prevent the formation of the toxic metabolite, 2-phenyl-acrylamide. Compositions comprising such derivative compounds have activity as anesthetics and as neuroprotec... | 08/19/2008 |
| 7402626 | Top coat composition The present invention relates to a top coat composition, which is characterized in that it is applied to a photoresist top surface by using a polymer containing at least one structure represented by the formula [1], [2] or [3]. It is possible to produce a top coat c... | 07/22/2008 |
| 7223747 | Halocombstatins and methods of synthesis thereof The invention relates to novel compounds denominated halocombstatins. The halocombstatins are derivatives of combretastatin A-3, and include compounds that exhibit cancer growth cell inhibition against a panel of human cancer cell lines and the murine P388 leukemia,... | 05/29/2007 |
| 7166337 | Liquid-crystal composition, methods of adjusting the resistance, and substituted phenols The present invention relates to liquid-crystal mixtures having specific resistance values, comprising acidic compounds. The present invention furthermore relates to liquid-crystal displays containing these liquid-crystal mixtures. The invention furthermore relates ... | 01/23/2007 |
| 7132294 | Functionalized small molecules for use in chemical sensors The invention provides a device for selective molecular recognition, the device comprising a sensing portion, wherein said sensing portion includes a substrate having coated thereon a layer comprising a non-volatile, small molecule compound having at least two penda... | 11/07/2006 |
| 7119123 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use Antimicrobially active 4-methyl-4-aryl-2-pentanols of the Formula 1 below, methods for the preparation of these compounds and their use as antimicrobial active compounds are described. Surprisingly, compounds of th... | 10/10/2006 |
| 7105618 | Fluorine-containing polymerizable monomers and polymers, anti-reflection film materials and resist compositions using same The present invention relates to a fluorine-containing polymerizable monomer having a structure of the general formula (1), where each of R1 and R2 is independently ... | 09/12/2006 |
| 7053251 | Bromination of hydroxyaromatic compounds A method for brominating hydroxyaromatic compounds to form products, such as p-bromophenol, is disclosed. The method uses elemental bromine as the brominating agent and comprises contacting a hydroxyaromatic compound with bromine and oxygen in the presence of metal ... | 05/30/2006 |
| 7022886 | Selective catalytic oxybromination of hydroxyaromatic compounds A method for selectively brominating hydroxyaromatic compounds is disclosed. Hydroxyaromatic compounds are contacted with oxygen and a bromine source, in an acidic medium, in the presence of a catalyst selected from the group of compounds and mixtures of compounds o... | 04/04/2006 |
| 6987205 | Process for the preparation of 1-(3-trifluoromehylphenyl)-propan-2-ol enantiomers A process for the preparation of 1-(3-trifluoromethylphenyl)-propan-2-ol enantiomersthrough enzymatic resolution by a lipase. ... | 01/17/2006 |
| 6943271 | Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same A fluorine-containing styrene monomer of the formula (2) is produced by a first, second or third process. The first process includes (a) reacting a compound of the formula (1) with a compound of the formula (3), in the presence of a metal catalyst; (b) reacting the ... | 09/13/2005 |
| 6894195 | Preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol A process for the preparation of 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol comprising hydrogenating 4-methyl-2,3,5,6-tetrafluorobenzonitrile to 4-methyl-2,3,5,6-tetrafluorobenzylamine and converting 4-methyl-2,3,5,6-tetrafluorobenzylamine to 4-methyl-2,3,5,6-tetraf... | 05/17/2005 |
| 6881868 | Process for the preparation of (R)-2-alkyl-3-phenyl-1-propanols Compounds of formula (I), wherein R1 and R2 are, independently of one another, H,C1-C6alkyl, C1-C6halogenalkyl, C1-C6alkoxyl, C1-C6alkoxy-C1-C | 04/19/2005 |
| 6828467 | Process for producing fluorinated methyl-benzyl alcohol An object of the present invention is to provide a process for producing a fluorinated methyl-benzyl alcohol, which process is industrially applicable. A process for producing a fluorinated methyl-benzyl alcohol according to the present invention includes hydrogenol... | 12/07/2004 |
| 6825383 | Catalytic process for regiospecific chlorination of alkanes, alkenes and arenes The present invention provides a process for regiospecific chlorination of an aromatic or aliphatic compound with a chlorine source comprising a metal chloride and other than Cl2 and SO2Cl2 in presence of hypervalent iodine catalyst ... | 11/30/2004 |
| 6777580 | Process for the synthesis of (R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol by asymmetric transfer hydrogenation The present invention is concerned with novel processes for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity. ... | 08/17/2004 |
| 6756375 | 10-Aryl-11h-benzo[b]fluorene derivatives and analogs for medicinal use The invention provides for a non-steroidal compound having the formula wherein Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2— or —CH2C... | 06/29/2004 |
| 6753444 | Method for producing 2,3,5,6-tetrahalogen-xylyidene compounds The invention relates to a process for preparing 2,3,5,6-tetrahaloxylylidene compounds of formula (I) where each Hal is independently fluorine or chlorine, and X is fluorine, chlorine, bromine, —O—R, or —O—C(═O... | 06/22/2004 |
| 6673976 | Process of making fluorinated alcohols Provided are methods of producing fluorinated alcohols from non-perfluorinated fluoroolefins and methanol. Certain preferred embodiments of such methods involve advantageously reacting a non-perfluorinated fluoroolefin with methanol under ambient-pressure... | 01/06/2004 |
| 6667422 | Process for the preparation of -haloketones A process for preparing an -haloketone of the formula (1) ##STR1## where R1 is an optionally heteroatom-containing and optionally substituted hydrocarbon radical, R2 is a hydrogen, alkyl, aralkyl or aryl radical, and X is a halogen... | 12/23/2003 |
| 6660884 | Catalysts, methods for making said catalysts, and methods for making chiral compounds with high enantioselectivity The present invention relates to compounds useful as catalysts in asymmetric synthesis of chiral compounds, methods for the synthesis of said catalysts, and methods for synthesizing chiral compounds with high enantioselectivity.... | 12/09/2003 |
| 6624336 | Process for producing tetrafluorobenzenemethanols The present invention relates to a process by a series of reactions using tetrafluorocyanobenzens as material for producing tetrafluorobenzenemethanols, tetrafluorobenzenecarbaldehyde dialkylacetals and tetrafluorobenzenecarbaldehydes in a high purity and... | 09/23/2003 |
| 6566561 | Fluoro-alcohol phase modifiers and process for cesium solvent extraction The invention relates to a class of phenoxy fluoro-alcohols, their preparation, and their use as phase modifiers and solvating agents in a solvent composition for the extraction of cesium from alkaline solutions. These phenoxy fluoro-alcohols comply with ... | 05/20/2003 |
| 6541674 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium A process for condensing at least one carbonyl compound carrying at least one electron-withdrawing group with an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound i... | 04/01/2003 |
| 6528538 | Cyclic compounds useful in the treatment of dyslipidaemia, atherosclerosis and diabetes, pharamaceutical compositions and preparation process The present invention relates to cyclic compounds which are of the class of compounds of formula I wherein X and Y represent an oxygen atom and to processes for preparing such compounds. The compounds are useful in the treatment of dyslipidemia, atheroscl... | 03/04/2003 |
| 6504066 | Process for the synthesis of (R)-1-(3,5-bis(trifluoromethyl)-phenyl)ethan-1-ol by asymmetric transfer hydrogenation The present invention is concerned with novel processes for the preparation of (R)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-ol. This compound is useful as an intermediate in the synthesis of compounds which possess pharmacological activity.... | 01/07/2003 |
| 6479712 | Method for preparing perfluorocarbon-substituted methanols Methods for producing perfluorocarbon monomethanols or dimethanols are disclosed. The methods of the invention can provide branched perfluorocarbon monomethanols or dimethanols with good purity and yields.... | 11/12/2002 |
| 6476279 | Method of making fluorinated alcohols Disclosed are methods of producing fluorinated alcohols which find particular use in the syntheses of pharmaceutical drugs. The methods comprise generally, the steps of (a) reacting a halogenated alkane with an alkyl vinyl ether to form an unsaturated hal... | 11/05/2002 |
| 6462242 | Process for preparing benzyl alcohols and their use Benzyl alcohols, particularly those which bear fluorine substituents or fluoroalkyl substituents on the benzyl ring, can be obtained by formylation of corresponding aryl bromides to form benzaldehydes and reduction of the latter using further formate, whe... | 10/08/2002 |
| 6452056 | Process for the preparation of fluorobenzyl derivatives A fluorine-containing benzonitrile derivative (formula 1) is subjected to a reduction reaction to obtain a fluorine-containing benzylamine derivative (formula 2), and the amino group in said fluorine-containing benzylamine derivative is replaced with a hy... | 09/17/2002 |
| 6407298 | Process for the preparation of (p-chlorophenyl)propanol derivatives A process for the preparation of an alcohol compound (1), characterized by subjecting p-iodochlorobenzene to Pd coupling with allyl alcohol in the presence of tetramethylammonium chloride, followed by reduction, and a process for the preparation of a comp... | 06/18/2002 |
| 6372921 | Process for producing isochromanones and intermediates thereof (1) Methods for producing isochromanone compounds from o-xylene compounds as starting compounds through -halogeno-o-xylene derivatives, -cyano-o-xylene derivatives, and -halogeno-'-cyano-o-xylene derivatives, and (2) methods fo... | 04/16/2002 |
| 6218581 | Process of producing optically active alcohol The present invention relates to a process of producing optically active alcohol having high optical purity by performing an enzyme conversion reaction on a raw material serving as the substrate, examples of which include racemic alcohol, ketone and the a... | 04/17/2001 |
| 6207865 | Method for the hydrogenation of carbonyl compounds A carbonyl compound or a mixture of two or more carbonyl compounds is catalytically hydrogenated in the presence of a Raney copper catalyst in the form of nuggets.... | 03/27/2001 |
| 6194606 | Intermediates The present invention provides compounds having the formula: ##STR1## in which R is hydrogen or C1 -C4 alkyl, preferably hydrogen and Y is hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy, CF3, ... | 02/27/2001 |
| 6187966 | Process for preparing optically active alcoholic compounds A process for preparing optically active alcoholic compounds wherein a carbonyl compound is assymmetrically reduced in an economical and practical manner. The process comprises treating a prochiral carbonyl compound represented by the general formula (1) ... | 02/13/2001 |
| 6156940 | Process for producing optically active carbinols The present invention relates to a process for producing optically active halomethyl phenyl carbinols of the formula (1), comprising reducing halomethyl phenyl ketones of the formula (2) using an asymmetric reducing agent obtained from boranes and optical... | 12/05/2000 |
| 6046354 | Diacyloxy propanol derivatives A novel glycerol derivative, a process for preparing the same, and a process for preparing a triazole derivative. An optically active 2-arylglycerol derivative which is novel and useful as a synthetic intermediate of medicament is provided, and furthermor... | 04/04/2000 |
| 6043400 | Chlorohydrin process This invention is a process for preparing chlorohydrins by reacting a chlorinating species, such as hypochlorous acid, with at least one unsaturated organic compound, such as propylene or butylene, at a pH of greater than 6.0. The chlorinating species is ... | 03/28/2000 |