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Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 7420074 | Process for fluoro derivative-substituted aryl pnictogens and their oxides A process to prepare substituted aryl pnictogen derivatives comprising contacting a fluoropolyether or fluoroalkyl primary bromide or iodide, with a pnictogen derivative such as triaryl phosphine, triaryl arsine, or triaryl stibine or triaryl phosphine oxide, triary... | 09/02/2008 |
| 7396948 | Process for fluoro derivative-substituted aryl pnictogens and their oxides A process to prepare substituted aryl pnictogen derivatives comprising contacting a fluoropolyether or fluoroalkyl primary bromide or iodide, with a pnictogen derivative such as triaryl phosphine, triaryl arsine, or triaryl stibine or triaryl phosphine oxide, triary... | 07/08/2008 |
| 7078571 | Preparation of 1,3-di-halo-substituted benzene derivatives A process for preparing 1,3-di-halo-substituted benzene derivatives (II) from 2,6-di-halo-substituted benzaldehydes (I) (where X1, X2 are each independently F, Cl, Br, and R1, R2, R3 are each independently H, ha... | 07/18/2006 |
| 6949551 | Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides Dihalopropene compounds, process for their preparation, compositions comprising them and their use as pesticides What is described are dihalopropene compounds of the formula (I) in which R1 and R... | 09/27/2005 |
| 6943271 | Process for producing fluorine-containing, polymerizable styrene monomer and intermediates used in same A fluorine-containing styrene monomer of the formula (2) is produced by a first, second or third process. The first process includes (a) reacting a compound of the formula (1) with a compound of the formula (3), in the presence of a metal catalyst; (b) reacting the ... | 09/13/2005 |
| 6891071 | Halogenated styrene compounds and very low-loss polymers made therefrom The invention is directed to polymerizable vinyl compounds having halogenated aromatic groups and to a method of synthesizing such compounds. In particular, the invention is directed to polymerizable aromatic vinyl compounds wherein, except for the vinylic hydrogen ... | 05/10/2005 |
| 6753444 | Method for producing 2,3,5,6-tetrahalogen-xylyidene compounds The invention relates to a process for preparing 2,3,5,6-tetrahaloxylylidene compounds of formula (I) where each Hal is independently fluorine or chlorine, and X is fluorine, chlorine, bromine, —O—R, or —O—C(═O... | 06/22/2004 |
| 6552088 | Biphenyl derivatives Biphenyl substituted amides with activity as antagonists of the neurokinin 1 (NK-1, substance P) receptor.... | 04/22/2003 |
| 6515163 | Hydrogenated phenanthrenes and their use in liquid-crystal mixture The invention concerns hydrogenated phenanthrenes of formula I ##STR1## wherein the parameters have the meanings given in the text and their use in liquid crystal compositions.... | 02/04/2003 |
| 6388146 | Polymerizable compound, polymerizable resin composition, cured polymer and liquid crystal display device The polymerizable compound of this invention is represented by general formula (I): ##STR1## where R is H, R', R'O, R'COO, or R'OCO, R' is a linear or branched alkyl group or alkenyl group having 1 to about 15 carbon atoms, A1 and A2 | 05/14/2002 |
| 6344247 | Terphenyl derivative, liquid-crystal composition, and liquid-crystal display element The present invention provides liquid crystalline compounds having a high voltage holding ratio and a low threshold voltage, little variation of these properties depending on temperature change, high Ɗn, and good compatibility with other liquid crystal m... | 02/05/2002 |
| 6320085 | Process for the preparation of benzyl-ethers ##STR1## The subject matter of the invention is the process for the preparation of mixed ethers of formula I, wherein Ar represents an aromatic or one or more heteroatom-containing moiety, optionally substituted by one or more C1-4 alkoxy, meth... | 11/20/2001 |
| 6312618 | Polar diphenyldiacetylene liquid crystals A new class of asymmetric polar diphenyldiacetylene liquid crystal compounds and method for preparation are disclosed. The new class of liquid crystal compounds comprises the basic structure: ##STR1## Wherein R1 is an alkenyl group having the g... | 11/06/2001 |
| 6291721 | Processes for the preparation of 2-arylvinyl alkyl ether and 1,4-diaryl-2-fluoro-2-butene compounds An improved process for the preparation of 2-arylvinyl alkyl ether compounds of the structural formula I ##STR1## In addition, the present invention provides an improved process for the preparation of 1,4-diaryl-2-fluoro-2-butene compounds of the structur... | 09/18/2001 |
| 6281250 | Retinyl ethers, derivatives and analogues and inhibition of breast carcinogenesis The present invention is directed to retinyl ethers, derivatives and analogues and their use in inhibiting breast carcinogenesis or breast cancer cell growth.... | 08/28/2001 |
| 6147224 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds of Formula 1, Formula 2 or Formula 3 where X is O, S, or (CR1 R1)n where n is 0, 1 or 2; Y is a bivalent radical having Formula 4 or Formula 5 where o is an integer from 1 to 4 ##STR1## or Y is a bivalent ar... | 11/14/2000 |
| 6127579 | Method of manufacturing 1-indanone A method of manufacturing the useful substance 1-indanone from easily obtainable materials consists of reacting an indanyl ether represented by the generic formula ##STR1## under basic conditions to give a novel substance which is the indenyl et... | 10/03/2000 |
| 6121330 | 5-Hydroxyalkyl substituted phenyls and their use in medicaments for the treatment of arteriosclerosis and hyperlipoproteinaemia The novel 5-hydroxy-alkyl-substituted phenyls are prepared by either reacting the corresponding benzaldehydes with the Grignard compounds and subsequently reducing the other functional groups or by reducing the corresponding benzoic esters by customary me... | 09/19/2000 |
| 6025310 | Organic compounds suited to lubricating films on magnetic recording media The invention provides novel organic compounds, and more particularly those having excellent lubricity, compatible with lubricating organic compounds having a benzene ring and a phosphazine ring and retaining stability free of hydrolysis for a prolonged p... | 02/15/2000 |
| 5942648 | Naphthalene derivatives Naphthalene derivatives of the fomula I ##STR1## in which: R1 is an alkyl or alkenyl radical which is unsubstituted, monosubstituted by CH or CF3 or monosubstituted by halogen and has 1 to 15 carbon atoms, it also being possible... | 08/24/1999 |
| 5911912 | Halovinyl ethers Halovinyl ethers of the general formula I ##STR1## in which R, A1, A2, A3, Z1, Z2, X1, X2, l, m and n are as defined herein are suitable as components of liquid-crystalline ... | 06/15/1999 |
| 5763681 | Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor A novel synthesis of compound having the formula: ##STR1## wherein T is a stabilizing spiro-linked polycycloalkylidene group, R3 is a C1 -C20 alkyl, aralkyl or heteroatom containing group, Y is an aromatic fluorescent... | 06/09/1998 |
| 5750549 | Cycloalkyl tachykinin receptor antagonists The present invention is directed to certain novel compounds represented by structural formula I: ##STR1## or a pharmaceutically acceptable salt thereof, wherein R3, R6, R7, R8, R11, R12 | 05/12/1998 |
| 5693251 | Optically active benzene derivatives, process for producing the same and liquid-crystalline composition containing said derivatives as liquid-crystalline compound and light switching elements An optically active phenol useful in the preparation of liquid crystalline compounds which is represented by the formula (V): ##STR1## wherein R2 represents an alkyl or alkoxyalkyl group having 1 to 20 carbon atoms optionally substituted b... | 12/02/1997 |
| 5686020 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method A mesomorphic compound represented by the following formula (I): ##STR1## wherein R1 denotes a linear or branched alkyl group having 1-18 carbon atoms capable of including one or non-neighboring two or more methylene groups which can be re... | 11/11/1997 |
| 5541351 | Cyclopentadiene type compounds and method for making Processes are disclosed for preparing compounds of the formula Z--R--Z where each Z can be selected from cyclopentadienyl type radicals such as substituted or unsubstituted cyclopentadienyl, indenyl, fluorenyl or tetrahydroindenyl or where one Z is Cl, Br... | 07/30/1996 |
| 5494605 | P-terphenyl derivatives and liquid crystalline compositions The p-terphenyl derivatives of the formula shown below are useful in preparing practical ferroelectric liquid crystalline compositions. The derivatives exhibit excellent chemical stability and display the chiral smectic C or smectic C phase over a wide te... | 02/27/1996 |
| 5492917 | Endothelin antagonists incorporating a cyclobutane Novel compounds of the general structural formula I: ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cere... | 02/20/1996 |
| 5457235 | Halogenated diphenyldiacetylene liquid crystals The present invention provides liquid crystals that are diphenyldiacetylenes of the general formulas: ##STR1## where W, X, Y and Z are, independently of one another, a halogen atom, a hydrogen atom or a trihalomethyl group, T1 and T2 | 10/10/1995 |
| 5442063 | Process for producing (E)-alkoxyimino or hydroxyimino-acetamide compounds and intermediates therefor The present invention relates to a process for producing (E)-alkoxyiminoacetamide compounds useful as agricultural fungicides and a process for producing (E)-hydroxyiminoacetamide compounds useful as intermediates for producing them. The present invention... | 08/15/1995 |
| 5416243 | Cyclofluoroalkylated fullerene compounds Cyclofluoralkylated fullerene compounds are prepared by reacting the fullerenes with a fluoroalkene as exemplified by tetrafluoroethylene or perfluoromethyl vinyl ether under thermolysis conditions as exemplified by temperatures of 200° C., pressure and ... | 05/16/1995 |
| 5403512 | Vinyl compounds, and a liquid-crystalline medium Vinyl compounds of the formula I ##STR1## in which the variables are as described in the claims. The compounds are useful as components in liquid-crystalline media.... | 04/04/1995 |
| 5399689 | Chlorophenylalkoxyalkyl compounds The present invention is concerned with novel chlorophenylalkoxyalkyl compounds of the general formula ##STR1## wherein R denotes an alkyl residue with 1 to 12 carbon atoms; n is a whole number of 2 to 7, ring A denotes trans-1,4-cyclohexylene or 1,4... | 03/21/1995 |
| 5389295 | Benzene derivatives, and a liquid crystal medium Benzene derivatives of the formula I ##STR1## in which n is 1 to 7, Q is --CO or --(CH2)r --, where r is 1 to 5, s is 0, 1 or 2, t is 0 or 1, where s+tࣙ1, X is F, Cl, --CF3, --CN, --OCF3 or --OCHF2 | 02/14/1995 |
| 5382379 | Cyclohexane derivative A novel liquid crystal material having an alkenyl group at the end of the molecule, and having a low viscosity is provided. When the compound is added to a display element it is able to reduce the threshold voltage of the resulting display element. The co... | 01/17/1995 |
| 5382380 | P-terphenyl derivatives and liquid crystalline compositions New p-terphenyl derivatives useful as components for preparing practical ferroelectric liquid crystalline compositions and excellent in chemical stability, as well as liquid crystalline compositions containing at least one of the p-terphenyl derivatives.... | 01/17/1995 |
| 5382718 | Cyclofluoroalkylated fullerene compounds Mixtures of cyclofluoroalkylated fullerenes are provided by the thermal 2+2 cycloaddition of fluoroalkenes to a solution or slurry of a fullerene. The cyclofluoroalkylated fullerene mixtures are useful as lubricants or additives to lubricants; in fluoroca... | 01/17/1995 |
| 5364560 | Liquid crystal compound and liquid crystal display device An antiferroelectric liquid crystal compound which is a compound represented by ##STR1## wherein R denotes a linear aliphatic alkyl group having 6 to 14 carbon atoms; A denotes a single bond or an oxygen atom; X and Y independently denote a hydr... | 11/15/1994 |
| 5326898 | Substituted phenylethenyl compounds having retinoid-like biological activity Compounds of the formula ##STR1## wherein R1, R2, R3 and R4 independently are hydrogen, lower alkyl of 1 to 6 carbons, halogen or lower alkoxy of 1 to 6 carbons; R5 and R5 ' independen... | 07/05/1994 |
| 5324449 | Substituted phenyl trifluoromethyl ethers Substituted phenyl trifluoromethyl ethers of the formula I R1 --(A1 --Z1)n --A2 --Z2 --A3 --OCF3 I in which R1, A1 | 06/28/1994 |
