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| Number | Title | Issue Date |
| 7375252 | Compounds and method for the inhibition of the expression of VCAM-1 This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including cardiovascular and inflammatory diseases. ... | 05/20/2008 |
| 6982353 | C2-disubstituted indan-1-ol compounds, their derivatives, processes for their preparation, and their use as pharmaceuticals The present invention is directed to C2-disubstituted indan-1-ol systems of the Formula I, physiologically acceptable salts and physiologically functional derivatives thereof, and pharmaceutical compositions comprising... | 01/03/2006 |
| 6812257 | Polysubstituted indan-1-ol systems for the prophylaxis or treatment of obesity Polysubstituted indan-1-ol compounds of formula I, its physiologically acceptable salts and physiologically functional derivatives are disclosed Compositions comprising the same, methods of preparation and methods for ... | 11/02/2004 |
| 6717008 | Derivatives of C2-substituted indan-1-ol compounds, methods for their preparation and use Derivatives of C2-substituted indan-1-ol compounds, processes for their preparation and their use are disclosed. In particular, the invention relates to compounds of the formula I and to their physiologically acceptable ... | 04/06/2004 |
| 6518460 | Processes for preparing 3-arylsulfur hydroxamic acids This invention provides processes for the preparation of a compound of Formula I: Y--C(.dbd.O)--C(R1)(R2)--CH2 --S(O)n R3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl ... | 02/11/2003 |
| 6482988 | Sulfur compound containing terphenyl skeleton A liquid crystalline sulfur compound exhibiting high anisotropic factor of dipolemoment is provided. A terphenyl skeleton sulfur compound expressed by the general formula (I) is provided. A compound is preferred wherein, in the general formula (I), m is 1... | 11/19/2002 |
| 6479519 | Substituted anilides The invention is directed to physiologically active compounds of formula (I): ##STR1## wherein: R1 is hydrogen, halogen, hydroxy, lower alkyl or lower alkoxy; X1, X2 and X6 independently represent N or CR10 | 11/12/2002 |
| 6420573 | Processes for preparing 3-arylsulfur hydroxamic acids This invention provides processes for the preparation of a compound of Formula I: Y--C(.dbd.O)--C(R1)(R2)--CH2 --S(O)n R3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl ... | 07/16/2002 |
| 6379590 | Method for making unsymmetrically substituted fluorenyl compounds for nonlinear optical applications A new method for producing unsymmetrically substituted fluorenyl compounds, one step of which is the preparation of 2,7-disubstituted fluoren-9-one derivatives via the nucleophilic substitution of a compound of the formula D ##STR1## wherein A' is se... | 04/30/2002 |
| 6365781 | Process for the preparation of mercaptomethylphenois There is disclosed an improved process for the preparation of a compound of the formula I ##STR1## wherein n is 0 or 1, R1 is C1 -C12 alkyl or --CH2 SR3, R2 is C1 -C12... | 04/02/2002 |
| 6342639 | Processes for preparing 3-Arylsulfur hydroxamic acids This invention provides processes for the preparation of a compound of Formula I: Y--C(.dbd.O--C(R1)(R2)--CH2 --S(O)n R3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl o... | 01/29/2002 |
| 5998667 | Substituted biphenyl oxazolines The invention relates to new substituted biphenyloxazolines of the formula (I) ##STR1## in which R1 represents C1 -C6 -halogenoalkylthio and R2 represents hydrogen, or R1 and R2 together wi... | 12/07/1999 |
| 5952386 | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen... | 09/14/1999 |
| 5883287 | Vinyl sulfide compounds and a process for their preparation Vinyl sulfides bearing protected arlyoxy substituents and a process for their preparation are provided. In the process a vinyl sulfide is formed by coupling a ketone compound and a thioester compound with a low valent titanium reagent to form both carbon-... | 03/16/1999 |
| 5840991 | Antiatherosclerosis agents for lipid-lowering and antiperoxidative activity The invention relates to novel compounds of formula (I) ##STR1## wherein R1 represents hydrogen, hydroxy or alkoxy; R2, R3, R4 and R5 may be hydrogen or alkyl; and n is 0,1 or 2; and the pharmaceutically a... | 11/24/1998 |
| 5654331 | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics Diaromatic compounds, characterised in that they correspond to the following general formula: ##STR1## in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, -... | 08/05/1997 |
| 5534557 | Onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product The composition of the present invention is excellent in compatibility, transparency and curability and give a cured coat of excellent gloss and of less smell, and cured products of excellent properties can be obtained by curing the composition. The prese... | 07/09/1996 |
| 5464866 | Substituted hydrindanes for the treatment of angiogenesis-dependent diseases Substituted hydrindanes and their use in controlling angiogenesis-dependent diseases in warm blooded animals are disclosed.... | 11/07/1995 |
| 5426232 | Substituted tetracyanoquinodimethanes, processes for their preparation and their use Compounds of the formula I ##STR1## in which R1 and R2 independently of one another are C1 -C6 alkyl, C3 -C8 cycloalkyl which is unsubstituted or substituted by C1 -C4 | 06/20/1995 |
| 5371284 | Phenyl acetylenic acetals Phenyl acetylenic acetals and thioacetals and their use in the treatment of allergy, asthma, inflammation, arthritis, hyperproliferative skin disease, psoriasis or contact dermatitis are disclosed. Also disclosed are intermediates useful for producing sai... | 12/06/1994 |
| 5362915 | Phenyl-substituted cycloalkenyl compounds useful as PDE IV inhibitors A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein: R1 is --CH3 or --CH2 CH3 unsubstituted or substituted by 1 to 3 fluorines; X is O or S(O)s where s=0 to 2; R | 11/08/1994 |
| 5274002 | Trisubstituted phenyl analogs having activity for congestive heart failure Novel trisubstituted phenyl analogs are now found to have activity as for the treatment of congestive heart failure.... | 12/28/1993 |
| 5262439 | Soluble analogs of probucol The invention provides a class of water-soluble probucol derivatives having one or more ester groups replacing the phenyl hydroxyl groups of the probucol molecule. Some derivatives have polar or charged functionalities such as carboxylic acid groups, amin... | 11/16/1993 |
| 5214069 | Alcohol and ether derivatives The invention concerns a compound of the formula I, ##STR1## wherein Ar1 is optionally substituted phenyl or naphthyl; A1 is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene; Ar2 is optionally subs... | 05/25/1993 |
| 5208388 | 2,2-difluorocyclopropyl derivatives 2,2-Difluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl and X represents hydroxymethyl, 2-hydroxyethyl, isocyanato, amino, amino hydrohalide or a radical o... | 05/04/1993 |
| 5104559 | Hydrogen perfluoroalkylaromatic ethers and related compositions and methods A lubricating compound having the structure: R1 --Rf --O--Ar--R2 wherein R1 is a monovalent radical selected from the group consisting of fluoride, unsubstituted aryloxys, substituted aryloxys, unsubstituted arylthio... | 04/14/1992 |
| 5095147 | 2,2-difluorocyclopropyl derivatives 2,2-Difluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl and X represents hydroxymethyl, 2-hydroxyethyl, isocyanato, amino, amino hydrohalide or a radical o... | 03/10/1992 |
| 5084478 | Alkene, alkyne or cycloalkylene derivatives A compound of the formula ##STR1## wherein X has the formula --CR5 .dbd.CR6 --, --C.tbd.C-- or ##STR2## wherein ring A is phenyl, naphthyl or heterocyclic; wherein R1 is hydrogen, alkyl, alkanoyl or aroyl; wherei... | 01/28/1992 |
| 5081283 | Fluorocyclopropyl derivative fungicide intermediates Novel intermediates for fungicides, comprising fluorocyclopropyl derivatives of the formula ##STR1## in which R represents alkyl, optionally substituted aryl or optionally substituted aralkyl, X represents hydrogen, chlorine or bromine and R1 | 01/14/1992 |
| 5008459 | Substituted phenols as stabilizers Novel compositions are described which comprise an elastomer or a lubricant and at least one compound of the formulae I or II ##STR1## The symbols R1, R2, R3, Z1 and Z2 are as defined in claim 1.... | 04/16/1991 |
| 4990677 | Fungicidal and plant growth-regulating azolylmethyl-cyclopropyl derivatives Fungicidal and plant growth-regulating azolylmethylcyclopropyl derivatives of the formula ##STR1## in which R represents halogen, alkyl or optionally substituted phenyhl, or represents the groupings --Y--R2, wherein Y represents oxygen, su... | 02/05/1991 |
| 4931474 | Ether derivative and an acaricidal or insecticidal composition comprising said derivative An ether derivative compound of the formula: ##STR1## wherein R1 is hydrogen, chloro, methyl or (C1 -C3)-alkoxy, R2 is (C1 -C6)-alkyl, R3 is hydrogen, chloro, bromo, fluoro,... | 06/05/1990 |
| 4894109 | Method and apparatus for tacking together the copies of multicopy forms A method and apparatus for tacking together multipage forms having pin holes with the use of adhesive tacking tape.... | 01/16/1990 |
| 4874885 | Process for the preparation of mercaptomethylphenols There is disclosed a process for the preparation of compounds of formula I or II ##STR1## from phenols by reaction with formaldehyde and mercaptans in the presence of mono-, di- or trimethylamine or mono- or diethylamine. The symbols R1 is... | 10/17/1989 |
| 4837364 | Processes for preparing pentafluoroethoxy- and pentafluoroethylthiobenzene drivatives A process for the preparation of (pentafluoroethoxy)- and (pentafluoroethylthio)benzene derivatives either from phenol, thiophenol or from halobenzene. A halobenzene is reacted with trifluoroethanol or a phenol or a thiophenol is reacted with a compound o... | 06/06/1989 |
| 4816596 | Process for preparing trifluoroethoxybenzene or trifluoroethylthiobenzene A process for preparing substituted or unsubstituted trifluoroethoxy- or trifluoroethylthiobenzenes by reaction of a phenol or thiophenol, both of which may be substituted or unsubstituted, with a compound of the formula CF3 --CH2 --... | 03/28/1989 |
| 4792633 | Preparation of ortho-(alkyl- or arylthio)phenols Strong acids, e.g., aluminosilicates and sulfonic acids are employed as catalysts for the (alkyl or aryl)thiolation of phenols using dialkyl or diaryl disulfides and/or (alkyl- or arylthio)phenols as thiolating agents, and for the isomerization of (alkyl-... | 12/20/1988 |
| 4791123 | Insecticidal triffluormethyl alkane derivatives There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R1, R2, R3, R4 and A have the meanings given in the description, processes for their preparation and ins... | 12/13/1988 |
| 4788012 | Process for the preparation of benzyl trifluoromethyl sulfide A process for the preparation of a benzyl trifluoromethyl sulfide by bringing a benzyl thiocyanate and trifluoromethyl bromide into contact with zinc in a polar aprotic solvent or a pyridine. The invention also relates to a process for the preparation of ... | 11/29/1988 |
| 4745227 | Reversible photochromatic solid New compounds having the generic formula: ##STR1## wherein: X=halogen, Y= ##STR2## X=Y= ##STR3## X=Y= ##STR4## R=hydrogen, halogen such as chlorine, lower alkoxy such as methoxy, or lower alkyl such as methyl. These new compo... | 05/17/1988 |
