Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 7385087 | Method for producing a-(3-arylthio)-acetophenones A process for preparing α-(3-arylthio)acetophenones of the general formula I where the substituents R1 and R2 are each independently C1-C6-alkyl or an optionally substituted phen... | 06/10/2008 |
| 7300747 | Photobase generator and curable composition The photobase generator of the invention is represented by the following formula 1: wherein Ar, R, A+ and X− are as defined in the specification. Since the photobase generator of the formu... | 11/27/2007 |
| 7214831 | Histone deacetylase inhibitors based on alpha-chalcogenmethylcarbonyl compounds Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, for example, an alpha-chalcogenmethylcarbonyl group, such as an alpha-ketothio group, can inhibit histone deacetylase. Histone deacetylase inhibition can re... | 05/08/2007 |
| 7196229 | Benzoylcyclohexenone derivatives The invention relates to benzoylcyclohexenone derivatives of general formula (I) wherein the variables R1 to R10 and n have the designation cited in claim 1. The invention also relates to the salts of the same and the use of said derivat... | 03/27/2007 |
| 7135574 | Process for the preparation of cyclic diketones The present invention relates to a process for the preparation of compounds of formula I wherein the substituents are as defined in claim 1, by conversion of a compound of formula II | 11/14/2006 |
| 7012159 | Phenolic compounds and recording materials containing the same Phenolic compounds of general formula (I); and recording materials characterized by containing one of them and exhibiting high light stability wherein R1 and R2 are each hydrogen or C1-... | 03/14/2006 |
| 6929828 | Surface-active photoinitiators A process for the production of coatings having scratch-resistant durable surfaces, in which there is used a photocurable formulation comprising a surface-active photoinitiator, concentrated at the surface of the formulation, of formula (Ia) or (Ib), wherein R and R... | 08/16/2005 |
| 6906076 | Compounds and methods of use to treat infectious diseases The present invention concerns alkyl aryl carbonyl compounds that possess anti-infective activity. The compounds of the invention can be used to target specific nuclear localization signal, thereby blocking importation of specific proteins or molecular complex into ... | 06/14/2005 |
| 6815563 | Method for producing bicyclic 1,3-diketones A process for preparing bicyclic 1,3-diketones of the formula I where R1, R2, R3 and R4 are hydrogen, C1-C4-alkyl, C1-C4 | 11/09/2004 |
| 6576797 | Thioether substituted hydroxybenzophenones and stabilized compositions 2-Hydroxybenzophenone derivatives substituted in the 4'-position by a thioether moiety exhibit enhanced absorption in the UV at longer wavelength. Compositions comprising organic material subject to actinic degradation are beneficially stabilized with suc... | 06/10/2003 |
| 6525225 | Process for preparing diketone compounds and precursors thereto A process for preparing compounds of the formula: ##STR1## wherein R2 is lower alkyl; or phenyl optionally substituted by from one to five groups, the same or different, which are lower alkyl, lower haloalkyl, halogen or --SR4 ; R | 02/25/2003 |
| 6368769 | Aromatic sulfonium compounds, photoacid generators comprising the same, photopolymerizable compositions containing the same, stereolithographic resin compositions, and stereolithographic process ##STR1## Novel aromatic sulfonium compounds of general formula (I), photoacid generators comprising the same, and photopolymerizable compositions containing the same, capable of providing stereolithographic resin compositions which do not suffer from the ... | 04/09/2002 |
| 6350892 | Trifluoromethyl ketone analogs as selective cPLA2 inhibitors Selective inhibitors of the cPLA2 enzymes are provided which are of use in controlling a wide variety of inflammatory diseases. The inhibitors of the present invention have the general formula ##STR1## where (R'), p, D, Y, Z, Ra, R | 02/26/2002 |
| 6281391 | Synthesis of methylthiophenyl hydroxyketones This invention encompasses a novel process for synthesizing compounds represented by formula A: ##STR1## These compounds are intermediates useful in the preparation of certain agents that are selective COX-2 inhibitors.... | 08/28/2001 |
| 6235942 | Process for preparing diketone compounds A process for preparing compounds of the formula: ##STR1## wherein R2 is lower alkyl; or phenyl optionally substituted by from one to five groups, the same or different, which are lower alkyl, lower haloalkyl, halogen or --SR4 ; R | 05/22/2001 |
| 6229049 | Preparation process of difluoroacetophenone derivative The invention relates to a process for preparing a difluoroacetophenone derivative (4) by alkylthionating a compound (1) into a compound (2) and reacting this compound with a compound (3). ##STR1## wherein X1 is Cl, Br or I, X2 and X... | 05/08/2001 |
| 6225505 | Trifluoro methylthiomethyl benzene derivatives and process for production same The present invention lies in a process for producing a trifluoromethylthiomethylbenzene derivative represented by the following general formula (2): ##STR1## (wherein R is a hydrogen atom, a halogen atom, an alkyl group, an alkoxy group, an alkoxyca... | 05/01/2001 |
| 6204415 | Triazole derivative or salt thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient Described is a triazole derivative represented by the formula (1): ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represe... | 03/20/2001 |
| 6172266 | Triazole derivative or slat thereof, preparation process thereof and pharmaceutical containing said compound as an effective ingredient Described is a triazole derivative represented by the formula (1): ##STR1## wherein R1 represents a hydrogen atom, a lower alkyl group or an aralkyl group, X1 and X2 are the same or different and each independently represe... | 01/09/2001 |
| 6100431 | Process for the preparation of thioether-substituted aromatic ketones The preparation of aromatic ketones substituted with a thioether group at the ortho position is accomplished by the initial reaction of an aromatic nucleus substituted with a halide and an ortho nitro group with a nitroalkane in the presence of a hydroxid... | 08/08/2000 |
| 6096930 | Herbicidal cyclohexane-1,3-dione derivatives and their preparation process The present invention relates to novel cyclohexane-1-3-dione derivatives of formula (1) useful as herbicides and plant-growth regulants, ##STR1## wherein X is selected from the group consisting of hydrogen, halogen, C1 -C6 alkyl... | 08/01/2000 |
| 6080739 | Colchicine-skeleton compounds, their use as medicaments and compositions containing them The present invention relates to colchicine and thiocolchicine derivatives which can be obtained from these molecules by functionalization of the C-7 to ketone or functionalization of the amino group. Said compounds have a marked antiblastic activity both... | 06/27/2000 |
| 6025328 | Antitumor agents The present invention provides illudin analogs of the general formula I: ##STR1## wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceuticall... | 02/15/2000 |
| 6013839 | Process for preparing 2-(thiosubstituted)-4-haloacetophenones The invention relates to a process for preparing a 2-(thiosubstituted)-4-haloacetophenone such as those of formula (I), which comprises reacting a 2,4-dihaloacetophenone with a thiolating agent under substantially anhydrous conditions. In formula (I), R | 01/11/2000 |
| 5998667 | Substituted biphenyl oxazolines The invention relates to new substituted biphenyloxazolines of the formula (I) ##STR1## in which R1 represents C1 -C6 -halogenoalkylthio and R2 represents hydrogen, or R1 and R2 together wi... | 12/07/1999 |
| 5986144 | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient Described is a triazole derivative represented by the formula (1) or salt thereof, preparation process thereof, preparation intermediates represented by the formulas (2) and (3), and a pharmaceutical comprising the compound represented by the formula (1) ... | 11/16/1999 |
| 5932707 | Thioether-containing metal chelating compounds Ligands for radiopharmaceutical use are capable of chelating radiometal species and of being bound to biological targeting molecules. The ligands have the formula (a) and (b), where A, A'=--SZ or Y, B=O or S, Y=(c), Z=H or a thiol protecting group, m=2 or... | 08/03/1999 |
| 5821388 | Process for preparing -haloacetophenone derivative The present invention provides processes for preparing -halo(methylthio)acetophenone and -halo (methylsulfonyl)acetophenone in an industrially simple and economically advantageous manner. In the invention, methylthioacetophenone is halo... | 10/13/1998 |
| 5801120 | Substituted benzoyl (hetero) cyclic diones Substituted aryl or heteroaryl in particular benzoyl bicycloalkanediones and related compounds, intermediates therefor, synthesis thereof, and the use of said diones for the control of weeds.... | 09/01/1998 |
| 5798396 | Sulfonium salt-containing compounds and initiators of polymerization The present invention is directed to sulfonium salt-containing compounds represented by a following general formula; ##STR1## wherein R1 is alkyl containing from 1 to 18 carbon atoms, hydroxy, alkoxy containing from 1 to 18 carbon atoms, a... | 08/25/1998 |
| 5696282 | Process for producing organosulfur compounds A process comprises contacting, in the presence of a catalyst, hydrogen sulfide or a mercaptan such as, for example, n-dodecyl mercaptan with an ,ଲ-unsaturated carbonyl or ,ଲ-unsaturated cyano compound such as, for example, methy... | 12/09/1997 |
| 5559218 | 2-aroylcyclohexanediones and their use as herbicides or plant growth-regulating agents 2-Aroylcyclohexanediones I ##STR1## (A is C1 -C6 -alkylene; R1 is substituted phenyl or hetaryl which may furthermore carry a fused ring; R2 -R5 are each hydrogen or C1 -C4 ... | 09/24/1996 |
| 5536703 | Herbicidal substituted benzoyl bicycloalkanediones The invention relates to novel thioether derivatives of substituted benzoyl bicycloalkane diones, their use as herbicides and agricultural compositions comprising the same.... | 07/16/1996 |
| 5534557 | Onium salt, photopolymerization initiator, energy ray-curing composition containing the initiator, and cured product The composition of the present invention is excellent in compatibility, transparency and curability and give a cured coat of excellent gloss and of less smell, and cured products of excellent properties can be obtained by curing the composition. The prese... | 07/09/1996 |
| 5525580 | Substituted benzoyl cyclic enone, process for preparation, and herbicide Compounds represented by general formula (I), herbicides or selective herbicides for paddy field containing said compounds as active ingredients, method of controlling growth of undesirable plants by applying the herbicides on places where control is desi... | 06/11/1996 |
| 5514642 | Cyclohexenone oxime ethers, their preparation and their use Cyclohexenone oxime ethers of the formula I ##STR1##... | 05/07/1996 |
| 5492917 | Endothelin antagonists incorporating a cyclobutane Novel compounds of the general structural formula I: ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary hypertension, postischemic renal failure, vasospasm, cere... | 02/20/1996 |
| 5476876 | Di-tert-butylphenol compounds useful as anti-inflammatory agents The subject invention relates to compounds having the structure: ##STR1## wherein (a) X is selected from hydroxy, C1 to about C2 alkanoxy, thiol, C1 to about C2 alkanylthiol, and halo; (b) R and R' are each inde... | 12/19/1995 |
| 5463138 | Process for preparing difluoromethoxyarenes and difluoromethylthioarenes Difluoromethoxyarenes and difluoromethylthioarenes of the general formula (I), Ar--Q--CHF2 (I) in which Ar represents optionally substituted aryl, and Q represents oxygen or sulphur, (which can be used as interme... | 10/31/1995 |
| 5393776 | Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for atherosclerosis. Also provided are pharmaceutical compositions and a met... | 02/28/1995 |
