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| Number | Title | Issue Date |
| 7566808 | Management of ophthalmologic disorders, including macular degeneration A drug may be used in the preparation of a medicament for the treatment or prevention of an ophthalmologic disorder, wherein the drug inihibits, antagonizes, or short-circuits the visual cycle at a step of the visual cycle that occurs outside a disc of a rod photore... | 07/28/2009 |
| 7294448 | Composition sensitive to visible light The present invention provides a visible light-sensitive composition which is highly sensitive to a visible light and is useful as an electronic circuit forming material, a lithographic printing material, etc., said visible light-sensitive composition comprising (a)... | 11/13/2007 |
| 7214831 | Histone deacetylase inhibitors based on alpha-chalcogenmethylcarbonyl compounds Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, for example, an alpha-chalcogenmethylcarbonyl group, such as an alpha-ketothio group, can inhibit histone deacetylase. Histone deacetylase inhibition can re... | 05/08/2007 |
| 6753449 | Cleavable linker for solid phase synthesis Cleavable alkene-containing linkers and supports useful for the solid phase synthesis of chemical compounds, and combinatorial libraries of compounds, are disclosed. Also disclosed are methods of making and using the linkers and supports. ... | 06/22/2004 |
| 6310259 | Method for producing 6,10 and 6,9-dimethyl-5,10-undecadienyl-2-ones The present application refers to a process for preparing 6,10- and 6,9-dimethyl-5,10-undecadienyl-2-ones by telomerizing isoprene with alkyl acetoacetates in the presence of a catalyst system containing a transition metal compound catalyst and a phosphor... | 10/30/2001 |
| 6252106 | Method for stabilizing a sex pheromone compound An efficient method is proposed for the stabilization of a sex pheromone compound of insect pest, which is a long-chain aliphatic unsaturated ester, alcohol, ketone or hydrocarbon compound having at least ten carbon atoms and at least one double bond in a... | 06/26/2001 |
| 5856537 | Inhibitors of oleamide hydrolase Inhibitors of oleamide hydrolase, responsible for the hydrolysis of an endogenous sleep-inducing lipid (1, cis-9-octadecenamide) were designed and synthesized. The most potent inhibitors possess an electrophilic carbonyl group capable of reversibly formin... | 01/05/1999 |
| 5654487 | Catalyst composition and use in preparing polyketones Catalyst compositions for preparing polyketones comprising (a) a Group VIII metal compound, containing at least one ligand capable of coordinating to the Group VIII metal, and (b) a boron hydrocarbyl compound are disclosed, in particular catalyst composit... | 08/05/1997 |
| 5625069 | Process for preparing 2-cyano-3,5-dimethyl-4-methoxypyridine A process of preparing 2-cyano-3,5-dimethyl-4-methoxypyridine. The process includes the steps of: acylating 2-methyl-1-penten-1-alkoxy-3-one to obtain 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone; ammonolyzing 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone to obtain ... | 04/29/1997 |
| 5527968 | Process for the production of modified acrylic monomers A hydroxy-terminated linear carbonate is produced by reacting a cyclic alkylene carbonate such as neopentyl glycol carbonate with a substance having at least one alcoholic hydroxyl group in the presence of a catalyst. Mono- or polyhydric alphatic alcohols... | 06/18/1996 |
| 5300654 | Method for the preparation of unsaturated ketones ଲ-hydroxyketones are prepared by reacting an aldehyde with acetone in the presence of perhydroisoindole or pyrrolidine and water. The resulting ଲ-hydroxyketone is further reacted in the presence of a solvent mixture to produce -ଲ-... | 04/05/1994 |
| 5221797 | Process for the purification of pseudo-ionone and a complex formed during said process A process for the purification of pseudo-ionone, which comprises preparing pseudo-ionone by a reaction of citral with acetone, followed by bringing the reaction medium into contact with a metal derivative and thereafter distilling the pseudo-ionone.... | 06/22/1993 |
| 5073659 | Process for the preparation of terpenes A terpene compound having the formula (III) is produced by reacting an allylic halide having the formula (I) with a Grignard reagent having the formula (II) in the presence of anhydrous zinc chloride and a copper compound or an organic zinc halide compoun... | 12/17/1991 |
| 5017718 | Process for preparing polyfluoroalkyl-substituted compounds A process for preparing a perfluoroalkyl-substituted compound is disclosed. The process comprises reacting a halopolyfluoroalkane having 1 to 20 carbon atoms with a compound selected from the group consisting of (1) a substituted or unsubstituted ethylene... | 05/21/1991 |
| 4806693 | Process for the preparation of unsaturated ketones A process for preparing compounds of the general formula R represents an H atom or an optionally substituted hydrocarbyl group, by reacting a compound R--C.dbd.CH with CO in the presence of a Pd(II) compound, an organic phosphine and a protonic acid having a p... | 02/21/1989 |
| 4727195 | Process for the preparation of unsaturated ketones A process for preparing compounds of the general formula: R represents an H atom or an optionally substituted hydrocarbyl group, by reacting a compound R--C.tbd.CH with CO in the presence of a Pd(II) compound, an organic phosphine and a protonic acid having a ... | 02/23/1988 |
| 4625066 | Substituted acetylene-ketones Novel substituted acetylene-ketones of the formula in which R1 represents optionally substituted cycloalkyl with 4 to 7 carbon atoms or the groupings ##STR1## or represents optionally substituted aryl, if R2 represents optional... | 11/25/1986 |
| 4613706 | Isomer-directed process for producing asymmetric ketones using catalytic Claisen rearrangement of allylic ethers, intermediates, and uses of products and intermediates of process in perfumery Described is an isomer-directed process for producing asymmetric ketones defined according to the generic structure: ##STR1## wherein one of Z1 or Z2 is the moiety: ##STR2## and the other of Z1 or Z2 i... | 09/23/1986 |
| 4564477 | Polyprenyl compounds and method of producing the same There are provided polyprenyl compounds of the formula ##STR1## wherein ##STR2## represent a trans-isoprene unit and a cis-isoprene unit, respectively, n is an integer of 11-19, Z1 and Z2 combinedly represent .dbd.O, .... | 01/14/1986 |
| 4560791 | Synthesis of triconjugated dienones and intermediates used in said process Described is a process for preparing triconjugated dienones defined according to the structure: ##STR1## wherein R1 represents C1 -C8 alkyl, phenyl or phenyl methyl and wherein R2 represents hydrogen or C | 12/24/1985 |
| 4476147 | Flavoring of alliaceous-flavored foodstuffs A process for augmenting or enhancing the aroma or taste of alliaceous flavors, particularly garlic flavors, by augmenting or enhancing the garlic and green aroma and taste nuances of alliaceous-flavored foodstuffs comprising the step of adding to a allia... | 10/09/1984 |
| 4465863 | Branched C13 -alk-1-en-5-ones, use thereof in perfumery, process for preparing same and intermediates used in said process Described are compounds defined according to the structure: ##STR1## wherein R3, R4, R5, R6 and R7 represent hydrogen or methyl with the provisos that: (i) the sum total of carbon atoms in R3 | 08/14/1984 |
| 4456558 | Polyprenyl ketone derivatives This invention relates to novel polyprenyl ketone derivatives having the eral formula: ##STR1## in which n is an integer of 1-5, and R represents a hydroxymethyl, formyl or carboxyl group, and a process for the preparation of the same.... | 06/26/1984 |
| 4451392 | Synthesis of triconjugated dienones and novel intermediates used in said process Described is a process for preparing triconjugated dienones defined according to the structure: ##STR1## wherein R1 represents C1 -C8 alkyl, phenyl or phenyl methyl and wherein R2 represents hydrogen or C | 05/29/1984 |
| 4431844 | Preparation of polyunsaturated ketones An improved process for the preparation of unsaturated ketones of the general formula I ##STR1## where R1 is --CH3, ##STR2## and R2 and R3 are different and each is H or --CH3, by react... | 02/14/1984 |
| 4426321 | Odorant alkadienyl ketones, alcohols and oximes This invention discloses a number of novel odorant alkadienyl ketones, alcohols and oximes having from 9 to 15 carbon atoms, processes for making same and odorant compositions containing same.... | 01/17/1984 |
| 4412083 | Process for producing solanone, norsolanadione and intermediates therefor Described is a process for preparing solanone and norsolanadione using chemical intermediates defined according to the generic structure: ##STR1## wherein X is one of the moieties: ##STR2## wherein R represents hydrogen or methyl; wherein Y repr... | 10/25/1983 |
| 4380674 | Branched ketones, organoleptic uses thereof and process for preparing same Described are branched ketones defined according to the generic structure: ##STR1## wherein R4 ' represents C1 -C4 lower alkyl; wherein one of the dashed lines is a carbon-carbon double bond and the other of the dashe... | 04/19/1983 |
| 4374276 | Novel branched chain ketones and the process for preparing same Described are acylated derivatives of triisobutylene defined according to the generic structures: ##STR1## wherein, in each of the molecules one of the dashed lines represents a carbon-carbon double bond and each of the other of the dashed lines ... | 02/15/1983 |
| 4346237 | Branched ketones, organoleptic uses thereof and process for preparing same Described are branched ketones defined according to the generic structure: ##STR1## wherein R4 ' represents C1 -C4 lower alkyl; wherein one of the dashed lines is a carbon-carbon double bond and the other of the dashe... | 08/24/1982 |
| 4321255 | Use of branched ketones in augmenting or enhancing the aroma or taste of foodstuffs, chewing gums, toothpastes or chewing tobacco Described is the use in augmenting or enhancing the aroma or taste of foodstuffs, chewing gums, toothpastes or chewing tobaccos comprising the step of adding to a foodstuff, toothpaste, chewing gum or chewing tobacco an aroma or taste augmenting or enhanc... | 03/23/1982 |
| 4315911 | Flavoring with mixture of acetyl diisobutylenes Described for augmenting or enhancing the aroma or taste of foodstuffs, chewing gums, toothpastes and medicinal products are certain branched ketones having the generic structure: ##STR1## wherein one of the dashed lines is a carbon-carbon double bon... | 02/16/1982 |
| 4294972 | 1,2-Disubstituted oxo triazolidine Compounds of the formula (I): ##STR1## wherein n is 3 to 5; Y is --CH2 --CH2, --CH.dbd.CH-- or C.tbd.C--; L is O or S; R1 is C1-4 alkyl; R2 is hydrogen, C1-4 alkyl or phenyl; R3 is hy... | 10/13/1981 |
| 4292454 | Coupling reaction involving a Grignard and allylic halide Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or a... | 09/29/1981 |
| 4233453 | 15-Deoxy-16-hydroxy-16-allenyl prostane derivatives of the E and F series This invention disclosed herein relates to pharmacologically active 15-deoxy-16-hydroxy prostaglandin derivatives of the E and F series wherein C16 is substituted with allenyl. These compounds are active as hypotensives, antisecretory, bronchodilati... | 11/11/1980 |
| 4228313 | Coupling reaction involving a Grignard and allylic halide Disclosed is a process for the coupling of a Grignard reagent RMgX with an allylic halide in the presence of a dipolar aprotic solvent wherein the improvement, for obtaining improved yield and selectivity, comprises adding a catalyst to said Grignard or a... | 10/14/1980 |
| 4226810 | Splitting up pyran rings A chemical method for splitting the pyran ring of compounds such as 2,6,6-trimethyl-5,6-dihydro-4H-pyran is disclosed which consists in reacting the 4H-pyran derivatives concerned with water and a halogen-containing or halogen-donating catalyst at a compa... | 10/07/1980 |
| 4222963 | Substituted propargyl alcohols, allylic alcohols and unsaturated ketones, and methods for the production thereof Novel substituted propargyl alcohols of the formula: ##STR1## novel allylic alcohols of the formula: ##STR2## and; δ,&3xb5;-unsaturated ketones of the formula: ##STR3## are provided. In the above formulas, R represents a group of the formu... | 09/16/1980 |
| 4202822 | 1-Hydroxymethyl-1-oxo-prostane derivatives of the F1 series Derivatives, analogs, and congeners of prostane having a 1-(hydroxymethyl)-1-oxo-prostane structure in the F1 series.... | 05/13/1980 |
| 4197245 | 1-Hydroxymethyl-1-oxo-prostane derivatives of the A1 series Derivatives, analogs, and congeners of prostane having a 1-(hydroxymethyl)-1-oxo-prostane structure in the A1 series.... | 04/08/1980 |
