Class 564/55 - Plural benzene rings bonded directly to urea nitrogen

Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein more than one benzene ring is bonded directly
No. of patents: 62
Last issue date: 02/12/2008

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Number	Title	Issue Date
7329670	Inhibition of RAF kinase using aryl and heteroaryl substituted heterocyclic ureas The compounds are aryl and heteroaryl substituted heterocyclic ureas of the formula A—NH—C(O)—NH—B where A is the aryl or hetaryl substituted heterocyclic group and B is an aryl or heteroaryl moiety. The compounds inhibit raf kinase and are useful in the tre...	02/12/2008
7235576	Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy. ...	06/26/2007
7157601	Alkylated urea and triaminotriazine compounds and phase change inks containing same Compounds of the formulae wherein Z is —OR1, —SR1, —NR1R2, Y is —OR3, —SR3, or —NR3R4, at least one of R1	01/02/2007
7078475	Synergistic amine chain-extenders in polyurea spray elastomers Disclosed are derivatives of isophorone diamine exhibiting a synergistic relationship with other commonly employed chain extenders offering enhanced efficacy with regard to slowing of the polyurea elastomer cure profile, and processes employing their use. According ...	07/18/2006
7053244	Method for the continuous production of tetra-substituted ureas The invention relates to a process for the preparation of tetrasubstituted ureas by reaction of the corresponding amines with phosgene in the presence of an aqueous inorganic base at a temperature in the range from 0 to 150° C., which comprises: feedin...	05/30/2006
6927271	Hydroxyl and carbamate functional resins Coating compositions contain hydroxyl- or carbamate functional resins with a relatively low equivalent weight. The resins are based on a polyol core containing urea and hydroxyl groups, and made by reacting a polyisocyanate, preferably a triisocyanate, with an amino...	08/09/2005
6777561	Compounds Compounds of general formula I are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comprising the novel compounds and their use in therapy...	08/17/2004
6774233	Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents Disclosed are novel processes and novel intermediate compounds for preparing aryl- and heteroaryl-substituted urea compounds of the formula(I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in pharmaceutic c...	08/10/2004
6583282	Process for synthesis of heteroaryl-substituted urea compounds useful as antiinflammatory agents Disclosed are novel processes and novel intermediate compounds for preparing aryl- and heteroaryl-substituted urea compounds of the formula (I) wherein Ar1, Ar2, L, Q and X are described herein. The product compounds are useful in ph...	06/24/2003
6458998	Naphthalene ureas as glucose uptake enhancers Compounds of formula I are useful for treating conditions associated with hyperglycemia, especially Type II diabetes. These compounds are useful in stimulating the kinase activity of the insulin receptor, activating the insulin receptor, and stimulating t...	10/01/2002
6372933	Process for preparing certain phenyl urea compounds This invention relates to a process for making certain phenyl urea compounds by using a Lewis acid to effect the ring opening of a benzoxazolinone by an amine....	04/16/2002
6316503	LXR modulators The invention provides compounds, compositions and methods for modulating the effects of LXR in a cell. The compounds and compositions are useful both as diagnostic indicators of LXR function and as pharmacologically active agents. The compounds and compo...	11/13/2001
6262113	IL-8 receptor antagonists The present invention relates to novel compounds and a novel use of phenyl ureas in the treatment of disease states mediated by the chemokine Interleukin-8 (IL-8)....	07/17/2001
6214880	Arylsulfonanilide ureas The invention provides compounds, compositions and methods relating to novel arylsulfonanilide derivatives and their use as pharmacologically active agents. The compositions find particular use as pharmacological agents in the treatment of disease states,...	04/10/2001
6211373	Phenyl urea antagonists of the IL-8 receptor This invention relates to novel compounds of Formula (I), and a novel use of these compounds in treating chemokine mediated diseases, wherein the chemokine binds to an IL-8 a or b receptor. Compounds of Formula (1) are represented by the structure: #...	04/03/2001
5958375	Urea-linked, iodinated bis phenyl compounds for X-ray contrast media The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula I ##STR1## (wherein each C6 R5 moeity may be the same or different; each R denotes a hydrogen or iodine atom or a group M, two or...	09/28/1999
5958376	Iodinated X-ray contrast media The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula (I) (wherein each C6 R5 moiety may be the same or different; each denotes a hydrogen or iodine atom or a group M, two or three non-adj...	09/28/1999
5902899	Process for preparing 1, 3-disubstituted urea Process for preparing 1,3-disubstituted urea of the formula: ##STR1## wherein R5 is the same as or different from R6, and each of R5 and R6 is independently linear or branched, alkyl of 1-20 carbon atoms, a...	05/11/1999
5423905	Moth- and beetle-proofing formulation The invention relates to a formulation for protecting keratinous material from attack by pests that feed on keratin, comprising (A) at least one diphenylurea of formula ##STR1## wherein R1 is hydrogen or 4-chlorophenoxy-6-sulfonate, R	06/13/1995
5416118	Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase Novel bicyclic amides of the formula ##STR1## wherein Ar1 and Ar2 are phenyl, R2 -substituted phenyl, heteroaryl or R2 -substituted heteroaryl, wherein R2 is 1 to 3 substituents independently sel...	05/16/1995
5384425	Diurea derivatives useful as medicaments and processes for the preparation thereof Diurea derivatives are provided which can be represented by the following general formula and salts thereof: ##STR1## wherein, R1 and R2 are the same or different, and each represents C1 -10 alkyl group, a C3	01/24/1995
5380941	Preparation of aromatic ureas which contain a thioether or sulfonyl group A process for preparing ureas of the formula ##STR1## where the ring A can be substituted and benzo-fused and n is 0 or 2, R4 and R5 are hydrogen, C1 -C4 -alkyl or phenyl, L is unsubstituted or substituted C2	01/10/1995
5294582	Urea-superacid salts and their use as a curing catalyst of epoxy resins As a curing catalyst of epoxy resins, superacid salts of an N,N'-di- or N,N',N'-trisubstitued urea, the urea component of which is produced by reacting an organic isocyanate and a primary or secondary amine, at least one of which is monofunctional, are so...	03/15/1994
5248821	Process for preparing polyoxyethylene amines with urea linkages High molecular weight active polyoxyalkylene reaction product formed in two steps and containing urea or urethane and urea linkages are disclosed which contain as the principle reaction component, a diamine having the formula: ##STR1## or a diol...	09/28/1993
5241118	Process for the preparation of trisubstituted ureas by reductive carbonylation A process for preparing trisubstituted ureas is disclosed. A nitroarene is reacted with carbon monoxide and a secondary amine in the presence of a Group VIII transition metal catalyst and optionally one or more promoters selected from primary amines, hali...	08/31/1993
5227492	Diurea derivatives useful as medicaments and processes for the preparation thereof Diurea derivatives are provided which can be represented by the following general formula and salts thereof: ##STR1## Illustrative derivatives include 1,3-bis[[1-cycloheptyl-3-(3-pyridyl)ureido]-methyl]benzene, 1,3-bis[[1-cycloheptyl-3-(2-pyridy...	07/13/1993
5220061	Selective process for the preparation of diphenylmethane bis-(dialkyl ureas A selective process for the preparation of diphenylmethane bis(dialkylureas) is disclosed. An alkyl phenylcarbamate or an N,N-dialkyl-N'-phenylurea is reacted with a methylene bis(alkyl carbamate) in the presence of an acid catalyst. The use of a staged a...	06/15/1993
5198582	Process for preparing symmetric N,N'-disubstituted aromatic urea A process for preparing N,N'-disubstituted urea derivatives of the following formula (I) ##STR1## wherein Ar represents an unsubstituted aromatic radical or an aromatic radical substituted with a halogen atom, an alkyl group, or an alkoxy group,...	03/30/1993
5166429	Diurea derivatives useful as medicaments and processes for the preparation thereof Diurea Derivatives represented by the following general formula and salts thereof: ##STR1## The above compounds inhibit acyl-coenzyme A chloresterol acyl-transferase (ACAT enzyme), and thereby control the accumulation of cholesterol ester to the...	11/24/1992
5155267	Synthesis of isocyanate precursors from primary formamides A selective process for the production of unsymmetric carbamates and ureas is disclosed. In the process, a primary formamide is reacted with a dialkyl amine or an alcohol in the presence of a Group VIII transition metal catalyst. The unsymmetric carbamate...	10/13/1992
5091419	Diurea derivatives useful as medicaments and processes for the preparation thereof Diurea derivatives are provided which are represented by the following general formula and salts thereof: ##STR1## The above compounds inhibit acyl-coenzyme A cholesterol acyl-transferase (ACAT enzyme), and thereby control the accumulation of cholest...	02/25/1992
5091571	Process for preparing N,N'-disubstituted urea A process for preparing N, N-disubstituted urea and more particularly, to an improved process for preparing N,N'-disubstituted urea derivatives of the following formula (I) comprising ##STR1## wherein each of Ar1 and Ar2 represe...	02/25/1992
5064827	Polyhydroxybenzyloxpropanolamines Compounds of the present invention, are represented by the general formula ##STR1## wherein R1 group which may be alkyl of from 1 to about 6 carbon atoms, alkenyl of from 2 to about 6 carbon atoms, alkynyl of from 2 to about 10 carbon atom...	11/12/1991
5055544	Amino-functional polyesters containing urea, biuret, thiourea, dithiobiuret, thioamide, and/or amide moieties in their backbone and urethane/urea prepolymers and polymers made therefrom This invention relates to novel polymeric polyamines containing internal urea, biuret, thiourea, dithiobiuret, amide, and/or thioamide moieties, and to polymers prepared therefrom. This invention also relates to novel isocyanate-functional prepolymers con...	10/08/1991
5041477	Oligomeric aromatic dispersing agents, method of making same, and dispersions made therefrom An oligomeric aromatic pigment dispersant is the reaction product of a diisocyanate and a diol or diamine. The oligomeric dispersant is comprised of at least 25 weight percent of a compound of the formula: ##STR1## wherein n is an integer of from 3 t...	08/20/1991
4950789	Aromatic polyalkyleneoxy polyamines containing amioncarbonyl or aminothiocarbonyl moieties and a compatible mixture of high and low molecular weight polyols made therefrom Aromatic polyalkyleneoxy polyamines which are the reaction products of an aminocarbonyl, a polyalkyleneoxy polyamine, and aromatic diamines are useful in reaction injection molding processes to enhance the physical properties of the products produced. In ...	08/21/1990
4839406	Fluidity controlling agent for paints A fluidity controlling agent for paints is provided which comprises a product obtained by reacting paratoluidine and hexamethylene diisocyanate at a particular equivalent ratio (NH2 NCO) and gives thixotropic properties to the paint without sag...	06/13/1989
4822729	2,5-Diacylaminophenol-type color couplers and photographic elements containing same Cyan-forming color couplers according to the formula: ##STR1## wherein Z is hydrogen or a coupling off group, R1 is hydrogen, a halogen atom, alkyl, or alkoxy, R2 is hydrogen or alkyl, R3 is hydrogen, a halogen atom, ...	04/18/1989
4820871	Process for the preparation of N,N-diaryl-ureas N,N-Diaryl-ureas of the formula wherein R1 and R2 denote aryl and R3 denotes alkyl, aralkyl or aryl, can be prepared by a process in which a diarylamine of the formula is reacted with an isocyanate of the formula wherein R1	04/11/1989
4806653	Process for preparation of iminooxazolidines A process of the preparation of iminooxazolidines which comprises (a) reacting a urea alcohol of the formula ##STR1## X, Y, n and R are as defined, with a dehydrating agent to form an intermediate salt compound of the formula ##STR2## where...	02/21/1989

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Class 564/55 - Plural benzene rings bonded directly to urea nitrogen