Did You Know...
...that one person who claimed to be the inventor of the television is Russian emigre Vladimir Zworykin? In 1929 David Sarnoff, founder of RCA, asked Zworykin what it would take to develop TV for commercial use. He said: a year and a half and $100,000. In reality, it took 20 years and $50 million! Before his death in 1982 at the age of 92, Zworykin said of his invention: "The technique is wonderful. It is beyond my expectations. But the programs! I would never let my children even come close to this thing."
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| Number | Title | Issue Date |
| 8222451 | Histone deacetylase inhibitors and methods of use thereof The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the inventio... | 07/17/2012 |
| 7842835 | Histone deacetylase inhibitors and methods of use thereof The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the inventio... | 11/30/2010 |
| 7393961 | Polyhalogenated ethers (Per)haloethers having formula: X-(Rf)L-O—CF2CF2—O—CX1X2—CFX3X4 , (I) process for obtaining them and hypofluorites usable in the synthesis of said (per)hal... | 07/01/2008 |
| 7381840 | Tetrahydro-naphthalene derivatives This invention relates to tetrahydro-naphthalene derivatives and salts thereof which are useful as active ingredients of pharmaceutical preparations. They have the general formula (I) in which R1 represents hydro... | 06/03/2008 |
| 7371807 | Blocked biuretized isocyanates The present invention is directed to blocked biuret group-containing polyisocyanate compositions, wherein the blocking agent is of the formula: wherein R1, R2, R3 and R4 may be th... | 05/13/2008 |
| 7339020 | High-functionality polyisocyanates High-functionality polyisocyanates are prepared by a process which comprises (i) preparation of an addition product (A) which contains one group which is reactive toward isocyanate and at least two isocyanate groups by reacting | 03/04/2008 |
| 7332529 | Thermoreversible organogelators, compositions and methods of making thereof Thermoreversible organogelator compositions comprising compounds of the formula: where X is C6 to C12 alkylene and R is C9 to C12 alkyl, and their methods of us... | 02/19/2008 |
| 7326746 | Curable electron donor compositions Electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the aromatic ring. ... | 02/05/2008 |
| 7323532 | Low-viscosity radiation-curing and thermally curing polyisocyanates The present invention concerns a process for producing low-viscosity polyisocyanates or secondary products thereof, which carry activated, radiation-curable double bonds and can optionally also cure thermally, and low-viscosity polyisocyanate mixtures or secondary p... | 01/29/2008 |
| 7268111 | Therapeutic agents and methods of use thereof for the modulation of angiogenesis The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present i... | 09/11/2007 |
| 7220300 | Phase change inks containing bis(urea-urethane) compounds Disclosed is a phase change ink composition comprising a phase change ink carrier and a bis(urea-urethane) compound of the formula wherein R1 and R1′ each, independently of the other, is a... | 05/22/2007 |
| 7109375 | Zinc and zinc alloy electroplating additives and electroplating methods An additive for an alkaline zinc or zinc alloy electroplating bath medium, the additive comprising a random co-polymer comprising the reaction product of: (i) one or more di-tertiary amines including an amide or thioamide functional group, and (ii) optionally, one o... | 09/19/2006 |
| 7087676 | Blocked polyisocyanates Blocked polyisocyanates and one-component stoving systems containing these blocked polyisocyanates, and the preparation thereof and their use for the preparation of lacquers, paints, adhesives and elastomers, wherein blocked polyisocyanates are prepared by reacting ... | 08/08/2006 |
| 7084108 | Therapeutic agents and methods of use thereof for the modulation of angiogenesis The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present i... | 08/01/2006 |
| 7067553 | Thiourea compounds and the pharmaceutical compositions containing the same The present invention relates to thiourea compounds and the pharmaceutical compositions containing the same, and particularly, to novel thiourea compounds as an antagonist against vanilloid receptor (VR) and the pharmaceutical compositions thereof. As diseases assoc... | 06/27/2006 |
| 7037890 | Therapeutic agents and methods of use thereof for the modulation of angiogenesis The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present i... | 05/02/2006 |
| 7033522 | Pulverulent, water-dispersible, blocked polyisocyanate adducts, a process for the preparation and their use A blocked polyisocyanate adduct including 5 to 95% by weight of at least one isocyanate component having at least one NCO group, the isocyanate component selected from the group consisting of aliphatic, cycloaliphatic and aromatic isocyanates, wherein the isocyanate... | 04/25/2006 |
| 6908957 | Curable electron donor compounds Electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the aromatic ring. ... | 06/21/2005 |
| 6852885 | Production method of high purity organic compound There is provided a method for obtaining a target organic compound such as an alkyladamantyl ester efficiently by purifying a crude organic compound which contains, as impurities, sublimable materials which start to sublime at temperatures lower than a boiling point... | 02/08/2005 |
| 6841701 | Inhibitors for the blood-clotting factor Xa The invention relates to derivatives of amidino-benzylamine, especially derivatives of 4-amidino-benzylamine, with two bonded amino acids. These derivatives represent a novel group of highly active and very selective F Xa-inhibitors for treating cardiovascular disea... | 01/11/2005 |
| 6683151 | Supramolecular compound The invention relates to a compound comprising a reaction product of (A) an isocyanate functional compound of which at least 40 wt. %, relative to the total amount of (A), has a molecular weight of at least about 500, and (B) a nitrogen-containing compoun... | 01/27/2004 |
| 6656737 | Isocynate derivatizing agent and methods of production and use An organic compound useful for detecting the total quantity of isocyanate in an environmental sample is provided. The compound is 9-anthrcenylmethyl-1-piperazinecarboxylate (PAC), an isocyanate derivatizing agent. A process for producing PAC and methods f... | 12/02/2003 |
| 6635764 | Therapeutic ureas This invention relates to urea compounds that are muscarinic receptor antagonists and agonists, pharmaceutical compositions comprising such compounds, and methods of preparing these compounds.... | 10/21/2003 |
| 6620228 | Isocyanate-derived materials for use in phase change ink jet inks Resins and waxes made by reacting selected nucleophiles, including alcohols and/or amines, with an isocyanate are disclosed. The order of addition of the isocyanate and the different nucleophiles can tailor the distribution of di-urethane, mixed urethane/... | 09/16/2003 |
| 6583216 | Malonic ester-blocked HDI trimer with IPDA stabilization and formaldehyde stabilization The present invention relates to blocked polyisocyanate cross-linking agents and their use in one-component stoving lacquers, in particular in solvent-containing or predominantly water-based plastics coatings having a soft-feel effect.... | 06/24/2003 |
| 6548477 | Therapeutic agents and methods of use thereof for the modulation of angiogenesis The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. Th... | 04/15/2003 |
| 6545152 | R-isomers of nonnucleoside inhibitors Novel chiral derivitaves of non-nucleoside inhibitors (NNI), particularly R-isomers of halopyridyl and thiazoyl thiourea compounds are provided as potent inhibitors of reverse transcriptase (RT), and particularly of retroviral RT, most particularly HIV RT... | 04/08/2003 |
| 6514665 | Additives for improving post exposure delay stability of photoresist The present invention relates to a compound that is useful as an additive for improving post exposure delay stability in a photoresist composition, and a photoresist composition containing the same. In particular, it has been found that a compound of the ... | 02/04/2003 |
| 6452003 | Process for preparing low-odor and storage-stable monomer-containing polyisocyanurates from isophorone diisocyanate The present invention provides a process, which includes: partially trimerizing isophorone diisocyanate in the presence of a catalyst having the formula: [R--NX3 ].sym. Y.crclbar. wherein R and X are butyl groups and Y- i... | 09/17/2002 |
| 6448363 | Process for preparing highly reactive (semi)crystalline and amorphous blocked polyisocyanates The present invention provides a solventless, continuous process, which includes: in at least one extruder, intensive compounder, intensive mixer or static mixer, mixing and heating a reaction mixture including the following (A), (B), and one or both of (... | 09/10/2002 |
| 6420466 | Process for preparing a thixotropic agent and its use The invention relates to a process for preparing a solution that is active as a thixotropic agent and contains urea urethanes, in which monohydroxyl compounds are reacted with an excess of toluene diisocyanate, the unreacted portion of the toluene diisocy... | 07/16/2002 |
| 6410594 | Substituted cyclopentane compounds useful as neuraminidase inhibitors Compounds represented by formula (I), and pharmaceutically acceptacle salts thereof; and their method of preparation are provided. Compounds of the above formula are influenza virus neuraminidase inhibitors and can be used in treating patients infected wi... | 06/25/2002 |
| 6369073 | Compounds having reversible inhibiting activity of carnitine palmitoyl-transferase Compounds of formula (I) ##STR1## wherein the groups are as defined in the description are disclosed. The compounds of formula (I) are endowed with reversible inhibiting activity of carnitine palmitoyl-transferase and are useful in the preparation of medi... | 04/09/2002 |
| 6316573 | Solid adhesive material which peels off smoothly An adhesive paste, free of water, based on a reaction product of a polyisocyanate component and a co-reactant selected from the group consisting of a polyol, a monofunctional fatty derivative component and mixtures thereof, wherein the reaction product co... | 11/13/2001 |
| 6316478 | IL-8 receptor antagonists This invention relates to novel spiro compound derivatives of benzoisothiazolyl-urea and -thiourea and compositions thereof. These compounds are useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).... | 11/13/2001 |
| 6307001 | Curable hybrid electron donor compounds containing vinyl ether Hybrid electron donor compounds, suitable for use as adhesives or as components in adhesives, contain a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the aromatic ring and a vinyl ether moiety.... | 10/23/2001 |
| 6300456 | Compounds with electron donor and electron acceptor functionality Compounds containing both electron donor and electron acceptor functionality are suitable for use in adhesives. The electron donor group is a carbon to carbon double bond attached to an aromatic ring and conjugated with the unsaturation in the ring. The e... | 10/09/2001 |
| 6271261 | IL-8 receptor antagonists Novel IL-8 receptor antagonists and methods of using them are provided.... | 08/07/2001 |
| 6180745 | Moisture-curable compositions containing isocyanate and succinyl urea groups The present invention relates to moisture-curable compositions which have a) a content of (cyclo)aliphatically-bound isocyanate groups (calculated as NCO, MW 42) of 0.2 to 22% by weight and b) a content of succinyl urea groups (calculated as --NH--CO--N--, MW 57) ... | 01/30/2001 |
| 6114493 | Phosgenated oxime resins and their preparation This invention relates to methods for preparing novel, solid-phase transfer reagents, specifically phosgenated oxime resins and non-symmetrical ureas, that are useful as supports in combinatorial synthesis for the creation of libraries of compounds for le... | 09/05/2000 |
