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| Number | Title | Issue Date |
| 8017804 | Lipids, lipid complexes and use thereof The present invention is related to a compound according to formula (I), wherein R1 and R2 are each and independently selected from the group comprising alkyl; n is any integer between 1 and 4; R3 is an acyl selected from the group c... | 09/13/2011 |
| 7399879 | Process for preparing alkylidene-substituted-1,4-dions derivatives A process for the preparation of a monoalkylidene substituted 1,4-dions derivatives of formula (Ia) or (Ib) or a mixture of (Ia) and (Ib): wherein: R1, R2 and R3, equal to or different from each other, are hydrogen atoms or C1 | 07/15/2008 |
| 7351862 | Alpha, omega-difunctional aldaramides Alpha, omega-difunctional aldaramides, in particular diaminoaldaramides, dihydroxyaldaramides, bis(alkoxycarbonylalkyl)aldaramides, and bis(carboxyalkyl)aldaramides, and processes for preparing the aldaramides are provided. ... | 04/01/2008 |
| 7332485 | Peptide deformylase inhibitors Novel PDF inhibitors and novel methods for their use are provided. ... | 02/19/2008 |
| 7223887 | Multivalent cationic lipids and methods of using same in the production of lipid particles A multivalent cationic lipid having a positively-charged head group including two quaternary amine groups and a hydrophobic portion including four hydrocarbon chains, which may be the same or different and which are optionally substituted alkyl and alkenyl groups, t... | 05/29/2007 |
| 7091374 | Fluorinated compounds Fluorinated compounds and emulsions including the compounds. The compositions are useful as oxygen carriers and surfactants. In one embodiment, the fluorinated compound is pH sensitive. In one embodiment, the fluorinated compound is a vitamin E derivative. In one em... | 08/15/2006 |
| 6966944 | Anticurling agent, ink jet ink, method for ink jet recording and method for reducing curling The present invention provides an anti-curl agent containing an amide compound of specific structure and molecular weight, an ink jet ink containing the amide compound, a method for ink jet recording to form images by ejecting the ink, and a method for reducing curl... | 11/22/2005 |
| 6930203 | Gelling agents or thickeners The present invention relates to a novel class of gelling agents or thickeners, to a process for preparing gelling agents or thickeners and to their use to prepare the gels. The present gelling agents or thickeners have the form of an N,N′-disubstituted aldaramide... | 08/16/2005 |
| 6861525 | Process for the preparation imidazo[1,2-A]pyridine-3-acetamides The present invention relates to an improved synthesis of imidazo[1,2-a]pyridine-3-N,N-dialkylacetamides, including zolpidem tartrate. ... | 03/01/2005 |
| 6846955 | Process for racemising an enantiomer-enriched schiff base of an amino acid amide The invention relates to a process for racemising an enantiomer-enriched Schiff base of a primary amino acid amide with a strong base that is chemically reactive towards water. The reaction is conducted in an organic solvent. Preferably a metal alkoxide, a metal alk... | 01/25/2005 |
| RE38506 | Potent inducers of terminal differentiation and methods of use thereof The present invention provides the compound having the structure: wherein each of R1 and R2 are independently the same as or different from each other; when R1 and R2 are the same, each i... | 04/20/2004 |
| 6703368 | Peptide-containing -ketoamide cysteine and serine protease inhibitors This invention relates to peptide-containing -ketoamide inhibitors of cysteine and serine proteases, methods for making these compounds, and methods for using the same.... | 03/09/2004 |
| 6696424 | Cytofectin dimers and methods of use thereof A composition is provided comprising a novel cationic lipid compound having hydrophobic tails and two quaternary ammonium headgroups bridged by a linker. The composition is useful as a cytofectin for facilitating delivery and transfection of biologically ... | 02/24/2004 |
| 6624184 | Amide and diamide inhibitors of IMPDH enzyme for use in treating IMPDH-associated disorders The present invention discloses the identification of the inhibitors of IMPDH (inosine-5'-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as... | 09/23/2003 |
| 6566409 | Lock and key micelles A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefro... | 05/20/2003 |
| 6555580 | Amino- and amido-diphenyl ethers The invention relates to novel amino- and amido-diphenyl ethers, processes for their preparation and their use in pharmaceuticals, in particular for the indications of arteriosclerosis and hypercholesterolaemia.... | 04/29/2003 |
| 6552226 | Tandem acyl-Claisen rearrangement in the preparation of chiral products A novel tandem acyl-Claisen rearrangement reaction is provided. An allylic reactant such as an allylic amine or an allylic thioether, having at least two functional groups that enable the reactant to undergo at least two successive Claisen rearrangement r... | 04/22/2003 |
| 6476263 | Compounds for inhibiting ଲ-amyloid peptide release and/or its synthesis Disclosed are compounds which inhibit ଲ-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ଲ-amyloid... | 11/05/2002 |
| 6455715 | Method of producing dicarboxylic acids suitable for synthesis of polymers or polyamides A method is described for producing saturated dicarboxylic acids with a chain length of C6 to C21 or the corresponding diamidic dicarboxylic acids from fatty acid cleavage of unsaturated fatty acids or the bis-fatty acid diamides of these unsaturated fatt... | 09/24/2002 |
| 6455502 | Compounds and compositions as protease inhibitors The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.... | 09/24/2002 |
| 6384279 | Synthesis of a tetraamido macrocycle ligand from a novel diamidodiol A new composition of matter for a diamidodiol and a method for preparing the diamidodiol. The exemplary diamidodiol has the formula C15 H30 N2 O4 and is prepared by reacting a first quantity of 2-amino-2-methyl-... | 05/07/2002 |
| 6342576 | Urethanized ଲ-hydroxyalkylamide compound, a process for preparing it and its use for preparing powder coating materials A urethanized ଲ-hydroxyalkylamide compound, a process for its preparation, and powder coating materials containing them.... | 01/29/2002 |
| 6303723 | Process for polymerization of allylic compounds A process for preparing polymers of allylic amine compounds comprising: a) preparing a reaction mixture comprising: i) a polar reaction solvent; ii) at least one salt of an allylic amine compound; and iii) a free radical initiator comprising a water soluble non-ionic di... | 10/16/2001 |
| 6297400 | Synthesis of a tetraamido macrocycle ligand from a novel diamidodiol A new composition of matter for a diamidodiol and a method for preparing the diamidodiol. The exemplary diamidodiol has the formula C15 H30 N2 O4 and is prepared by reacting a first quantity of 2-amino-2-methyl-... | 10/02/2001 |
| 6270540 | Star-like poly(oxyalkyene)triamide alkoxylates gasoline additive and the method for producing the same A new class of useful gasoline additives is prepared via two consecutive reactions including: (1) amidation of water-soluble hydrophilic, low molecular weight triamine with alkyl acetate at an elevated temperature under N2 pressure to prepare a... | 08/07/2001 |
| 6194613 | Process for the continuous preparation of hydroxyalkylamides Process for the continuous preparation of hydroxyalkylamides Process for the continuous preparation of hydroxyalkylamides from carboxylic esters and alkanolamines, wherein the reaction of the starting materials is carried out in an extruder or intensive m... | 02/27/2001 |
| 6136943 | Multi-branched compounds and curable composition A multi-branched compound which can give a compound having a relatively high molecular weight but a low viscosity and having excellent coating performances, and can give a solvent-less composition having sufficient coating performances and having a low vi... | 10/24/2000 |
| 6103767 | Physiologically active substances TKR1785's, process for the preparation thereof, and microbe The object of the present invention is to provide a novel bioactive substance of value as a therapeutic agent for mycosis, and the like. This invention relates to the bioactive substance TKR1785 of the following general formula (A): ##STR1## (wherein... | 08/15/2000 |
| 6090950 | Chiral hydride complexes Novel chiral boron and aluminum hydride complexes, compositions comprising the chiral hydride complexes, and methods for their synthesis and use are described. The novel chiral hydride complexes are of the formulas: MBH4-n-a (R*)n (R') | 07/18/2000 |
| 6013837 | Aromatic amides, method for preparing and compositions containing same, and use thereof as pesticides The subject of the invention is the compounds of formula (I): Q(CH2)a-(X1)b -Q1 -Q2 -C(X2)--N(R1)(R2) (I) in which: Q represents an aryl radical, X... | 01/11/2000 |
| 5985824 | Methods and compositions for treating cystic fibrosis Methods and compositions for treating CF by mobilizing mutant forms of CFTR, which retain at least some functional activity, to the plasma membrane where they can mediate chloride ion transport are disclosed.... | 11/16/1999 |
| 5863919 | Lock and key micelles and monomer building blocks therefor A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefro... | 01/26/1999 |
| 5840978 | Process for preparing ethylidene bisformamide This invention describes an integrated process for making ethylidene bisformamide in high yield wherein water, which is formed as a reaction by-product, is readily removed from the reaction product mixture without adversely affecting the efficiency of the... | 11/24/1998 |
| 5834421 | Methods and compositions for treating cystic fibrosis Methods and compositions for treating CF by mobilizing mutant forms of CFTR, which retain at least some functional activity, to the plasma membrane where they can mediate chloride ion transport are disclosed.... | 11/10/1998 |
| 5801281 | Process for preparing 1,1'- (1,4- phenylenebis (methlene)-Bis 1,4,8,11-tetraazacyclotetradecane An improved process for preparing 1,1'-1,4-phenylenebis-(methylene)!-bis-1,4,8,11-tetraazacyclotetradecane comprising the selective functionalization of an acyclic tetraamine, and subsequent dimerization and hydrolyzation/tosylation to obtain a 1,4... | 09/01/1998 |
| 5789520 | Curing agent for resins and resin composition containing the same A curing agent having less odor and providing a cured resin which is excellent in appearance, mechanical properties, water resistance and chemical resistance, and a one-component type humidity-curing resin composition having excellent storage stability an... | 08/04/1998 |
| 5783712 | Vinyl ether compounds having additional functional groups other than vinyl ether groups and the use thereof in the formulation of curable compositions The invention relates to compounds having at least one vinyl ether group which also contain in the molecule at least one further functional group selected from acrylate, methacrylate, epoxy, alkenyl, cycloalkenyl and vinylaryl groups, to compositions, esp... | 07/21/1998 |
| 5762910 | Liposoluble compounds useful as magnetic resonance imaging agents Novel complexes of paramagnetic ions and compounds bearing long acyl chains have been synthesized as magnetic resonance imaging contrast agents. These novel liposoluble contrast agents may be administered alone, or with lipids, suspending agents or other ... | 06/09/1998 |
| 5753707 | Amide derivatives and their use in cosmetic composition An amide derivative represented by the following formula (1): ##STR1## wherein R1 represents a C1-40 hydrocarbon; R2 represents a C1-6 alkylene; R3 represents H, OH or alkoxyl; R4 repr... | 05/19/1998 |
| 5648534 | Method of producing cis-1-aminoindan-2-ol 1,2-di-substituted indan expressed by general formula (I) wherein X is a substituent which can be drawn out under an acidic condition to form a carbocation at 1-position of an indan skeleton, Y is a halogen atom, and X and Y can be in either cis- or trans... | 07/15/1997 |