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| Number | Title | Issue Date |
| 8067636 | Dihydrazide compounds, preparation and uses thereof Disclosed are dihydrazide compounds having formula (I) or (II), wherein R1-R4 are alkylene, substituted alkylene, aryl or polyether radical. The preparation and uses for producing medical hydrogel and medicine controlled releasing carrier of sa... | 11/29/2011 |
| 7638650 | Fluoroalkyl surfactants A compound of formula (I): wherein k is 1 or 2; Y is —CH2CH(CF3)2 or —(CH2)nCF; X is hydrogen, —(CH... | 12/29/2009 |
| 7368473 | Paclitaxel enhancer compounds One embodiment of the present invention is a compound represented by the Structural Formula (I): Y is a covalent bond of a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, taken together with b... | 05/06/2008 |
| 7288262 | Composition comprising a cyclohexane-based compound, compound and use of said compound to structure a composition Compositions, in particular cosmetic compositions, comprising a cyclohexane-based compound defined by formula (I): wherein: R, which may be identical or different, are each chosen from hydrogen atoms an... | 10/30/2007 |
| 7253169 | Aza compounds, pharmaceutical compositions and methods of use The present invention relates to N-substituted cyclic aza compounds, pharmaceutical compositions comprising such compounds, and methods of their use for effecting neuronal activities. ... | 08/07/2007 |
| 6825235 | Synthesis of taxol enhancers Disclosed is a method of preparing a thiohydrazide product compound from a hydrazide starting compound. The hydrazide starting compound is represented by Structural Formula (I): The thiohydrazide product compound is re... | 11/30/2004 |
| 6762204 | Taxol enhancer compounds One embodiment of the present invention is a compound represented by the Structural Formula (I): Y is a covalent bond of a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, taken together w... | 07/13/2004 |
| 6610715 | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same The present invention provides novel cathecol hydrazone derivatives of formula (I) or pharmaceutically acceptable salts thereof, wherein R1 is C1-7 alkyl or C3-7 cycloalkyl; R2 is hydrogen, hydroxy, C1-5 | 08/26/2003 |
| 6600071 | Method for producing 1-substituted 5-hydroxpyrazoles A process for preparing compounds of the formula I ##STR1## in which R1 is hydrogen, an aliphatic group having 1-8 carbon atoms, Cl -C6 -alkoxycarbonyl, Cl -C6 -alkylthiocarbonyl or a cyclic ring syst... | 07/29/2003 |
| 6433017 | Amphiphilic polyamine compounds In accordance with the present invention, there are provided amphiphilic polyamine compounds and derivatives thereof having the property of promoting transfection of polynucleotides and polypeptides into cells, and formulations comprising said compounds.... | 08/13/2002 |
| 6420600 | Phenylalaninol derivatives It has been discovered that compounds of the formula: ##STR1## and the pharmaceutically acceptable salts and esters thereof wherein X and Y are as defined below, are more readily absorbed and more bioavailable than the corresponding carboxylic acids from ... | 07/16/2002 |
| 6399659 | Hydrazine oxoacetamide derivative and insecticide The present invention relates to a hydrazine oxoacetamide derivative or its salt which exhibits an excellent insecticidal effect even at a low concentration. The hydrazine oxoacetamide derivative has the following Formula (I): ##STR1## wherein R... | 06/04/2002 |
| 6365745 | Method for producing hydrazine derivative The present invention provides a method for producing a hydrazine derivative of the formula [2]: ##STR1## wherein R1 is alkyl group having 1-12 carbon atoms and the like, R2 is alkyl group having 1-12 carbon atoms and the like, and A... | 04/02/2002 |
| 6348499 | Amphiphilic polyamide compounds Amphiphilic polyamide compounds and derivatives thereof having the property of promoting transfection of polynucleotides and polypeptides into cells, and formulations comprising said compounds.... | 02/19/2002 |
| 6346547 | N-substituted amino acids, antioxidant pharmaceutical compositions containing n-substituted amino acids and methods for preventing cardiovascular diseases and/or preventing and/or treating antioxidant responsive diseases therewith Low-toxicity, highly-bioavailable, pharmaceutical antioxidant compositions for preferred oral administration to mammals are provided which have at least one amino acid-based compound of the general formula (I): A--N(Z)--CH(R1)C(O)--Q (I) wherein A ... | 02/12/2002 |
| 6291464 | Aminopiperazine derivatives This invention relates to new aminopiperazine derivatives having the potentiation of the cholinergic activity, etc., and represented by general formula [I]. ##STR1## wherein R1 is lower alkyl, etc., R2 is aryl, etc., A is ##STR2## or --SO | 09/18/2001 |
| 6239151 | Compounds as inhibitor of tumor necrosis factor alpha release The invention provides hydrazine derivatives of the formula ##STR1## wherein R1 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl; R2 is an acyl group derived from an -, &#... | 05/29/2001 |
| 6235787 | Hydrazine derivatives Hydrazine derivatives of the formula ##STR1## wherein Y is CO or SO2 ; R1 is lower alkyl, lower alkenyl, lower cycloalkyl, lower cycloalkyl-lower alkyl, aryl or aryl-lower alkyl; R2 is lower alkyl, halo-lower alkyl, aryl-l... | 05/22/2001 |
| 6207862 | Precursors for the production of chiral 1,3-aminoalcohols The disclosure describes novel precursors for the preparation of chiral 1,3-aminoalcohols. The precursors are chiral 4-hydroxycarboxamides, 4-hydroxyhydroxamic acids, or 4-hydroxyhydrazides produced from chiral gamma-lactones, which in turn are derived fr... | 03/27/2001 |
| 6172108 | Hydrazide compounds Compounds of formula (I): R--NH--A--CO--NH--NH--(W)n --Z (I) wherein: n is 0 or 1, W represents --CO-- or S(O)r wherein r is 0, 1 or 2, Z represents a group selected from aryl, arylalkyl, heteroaryl and heteroarylalkyl, each optionally substi... | 01/09/2001 |
| 6096890 | Process for substituted hydrazides using carboxylic acids This invention provides a convenient process for the preparation of monoacylhydrazines from carboxylic acids or their salts and hydrazine or substituted hydrazine in the presence of a 1,3,5-triazine substituted with at least one chloro or fluoro. The resu... | 08/01/2000 |
| 6063819 | Neuroprotective poly-guanidino compounds which block presynaptic N and P/Q calcium channels Neuroprotective drugs are disclosed with at least 3 branches extending outwardly from a center atom or group, each branch having a guanidino group at its terminus. All branches preferably should be identical, and distributed around the center atom or grou... | 05/16/2000 |
| 5942644 | Precursors for the production of chiral vicinal aminoalcohols The disclosure describes new compositions of matter useful for the preparation of optically-active vicinal aminoalcohols. The compositions are chiral ଲ-hydroxycarboxamides, ଲ-hydroxyhydraxides, and ଲ-hydroxyhydroxamic acids.... | 08/24/1999 |
| 5912352 | Intermediates for the preparation of peptide analogues The invention relates to a novel process for the preparation of compounds of formula I ##STR1## wherein R1 is hydrogen or a suitable amino-protecting group, R2 is unsubstituted or substituted alkyl, R3 is hydrogen, aryl, h... | 06/15/1999 |
| 5824805 | Branched hydrazone linkers Branched hydrazone linkers for linking a targeting ligand such as an antibody to a therapeutically active drug. The point of branching is at a polyvalent atom and the number of drugs increases by a factor of two for each generation of branching. A preferr... | 10/20/1998 |
| 5753684 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 05/19/1998 |
| 5684197 | Process for preparation of hydrazides A process for producing a hydrazide of the formula: ##STR1## is disclosed. The process comprises reacting a hydrazone of the formula: ##STR2## wherein said hydrazone is in toluene, with a mixture of Grignard reagents, wherein said Grignard reage... | 11/04/1997 |
| 5599984 | Guanylhydrazones and their use to treat inflammatory conditions This invention concerns new methods and compositions that are useful in preventing and ameliorating cachexia, the clinical syndrome of poor nutritional status and bodily wasting associated with cancer and other chronic diseases. More particularly, the inv... | 02/04/1997 |
| 5567723 | Miticidal hydrazine compounds and their intermediates Compounds having the structural formula ##STR1## wherein R is C1 -C6 alkoxy or C1 -C6 alkyl; R1 is fluorenyl, thienyl, pyridyl or thiazolyl, unsubstituted or substituted by one or more substituen... | 10/22/1996 |
| 5445888 | Hydrazine compound, process for the preparation of the same, and nonlinear optical organic material A novel hydrazine compound represented by the formula (I) is disclosed. ##STR1## Also disclosed are a process for preparing the novel hydrazine compound comprising reacting a specific hydrazine compound and a specific acid halide, a nonlinear optical... | 08/29/1995 |
| 5399589 | Oxalyl hydrazide-hydroxamic acid derivatives, their preparation and their use as fungicides Oxalyl hydrazide-hydroxamic acid derivatives of the formula I ##STR1## where the substituents have the following meanings: R, R1, R2 and R3 independently of one another are hydrogen, substituted or unsubstituted alkyl, alk... | 03/21/1995 |
| 5399758 | Diacylhydrazine photo-reactive compounds Disclosed are a novel azide compound represented, for example, by the formula, ##STR1## wherein Rf represents a fluoroalkyl or fluoroalkylpolyether group, ##STR2## wherein R represents a divalent organic group having an ester bond, an... | 03/21/1995 |
| 5389680 | Fluoroalkenyl compounds and their use as pest repellents Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds, for example, 3,4,4-trifluoro-3-butene-1-amine or 3,4,4-trifluoro-3-butenoic acid, are particularly useful ... | 02/14/1995 |
| 5380873 | Homobifunctional agents for coupling enzymes and the like to antibodies and the like A coupling agent useful in conducting immunoassays, particularly assays for B12, is disclosed. The coupling agent has the formula ##STR1## Z and Z' can be the same or different and each is ##STR2## k, m and n are integers from 1 to 10, X is an a... | 01/10/1995 |
| 5367093 | Insecticidal phenylhydrazine derivatives Compounds having the structural formula ##STR1## where X, Y, R and Z are defined in the specification are disclosed. The compounds of this invention are effective for controlling mites, nematodes, rice planthopper, tobacco budworm, and southern corn ... | 11/22/1994 |
| 5310738 | Process for producing a hexahydropyridazine-1,2-dicarboxy derivative An industrial process which is a process for producing a hexahydropyridazine-1,2-dicarboxy derivative in good yield, is provided. By reacting a hydrazine dicarboxy derivative of the general formula (1): ROC--NH--HN--COR ... | 05/10/1994 |
| 5292951 | 1,3,4-oxadiazoles containing the pentafluorothio (SF5) group 1,3,4-Oxadiazoles of the formula ##STR1## are prepared by cyclization (dehydration) of the corresponding diacylhydines of the formula R1 C(O)NHNHC(O)R2 with phosphorous pentachloride or phosphorous oxychloride wherein R1 | 03/08/1994 |
| 5288727 | Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them The present invention relates to a hydrazone compound of the formula (I) or its salt, a process for its preparation, an intermediate of the formula (II-5), a pesticidal composition containing said hydrazone compound or its salt as the active ingredient, a... | 02/22/1994 |
| 5284732 | Silver halide photographic material A silver halide light-sensitive material containing a hydrazine compound represented by formula (I): ##STR1## wherein L1 represents a single bond, --O--, --S--, --NR6 --, --CO--, SO2 --, --P(O) (G2 R6 | 02/08/1994 |
| 5229417 | 2-(3-phenylpropyl)hydrazines and method of treating personality disorders Novel 2-(3-phenylpropyl)hydrazines, intermediates in and processes for the preparation thereof, and a method of treating personality disorders utilizing compounds or compositions thereof are disclosed.... | 07/20/1993 |
