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| Number | Title | Issue Date |
| 7399788 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them Disclosed is a series of N-deacetylthiocolchicine derivatives of formula (I) in which: the linker is a bivalent straight or branched C1-C8 alkyl residue, C3-C8 cycloalkyl, a phenylene or heterocyclic C4-C6 ... | 07/15/2008 |
| 7317125 | Diacylglycerol acyltransferase inhibitors Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutica... | 01/08/2008 |
| 7304161 | Diaclhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex The present invention relates to non-steroidal ligands for use in nuclear receptor-based inducible gene expression system, and a method to modulate exogenous gene expression in which an ecdysone receptor complex comprising: a DNA binding domain; a ligand binding dom... | 12/04/2007 |
| 7220870 | Hydrolytic kinetic resolution of cyclic substrates The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisome... | 05/22/2007 |
| 7189873 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms The invention relates to 4-propargyloxy-benzyl dervatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl or optionally ... | 03/13/2007 |
| 7173063 | Topoisomerase poisons for the treatment of proliferative disorders Methods for the treatment of a proliferative disorder are provided in which a subject in need of such treatment is administered an effective amount of a compound selected from: compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein X1 | 02/06/2007 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6706765 | Aminoguanidines and alkoxyguanidines as protease inhibitors Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: wherein X is O or NR9 and R1-R4, R6-R9, R11, R12, Ra | 03/16/2004 |
| 6518310 | Aminoguanidines and alkoxyguanidines as protease inhibitors Aminoguanidine and alkoxyguanidine compounds, including compounds of the formula: ##STR1## wherein X is O or NR9 and R1 -R4, R6 -R9, R11, R12, Ra, Rb, R | 02/11/2003 |
| 6455515 | Salicylohydrazide derivatives, processes and intermediates for their preparation, compositions comprising them, and their use Salicylohydrazide derivatives of the formula I ##STR1## in which the index and the substituents have the following meanings: X is halogen, NO2, cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to differ from each o... | 09/24/2002 |
| 6207862 | Precursors for the production of chiral 1,3-aminoalcohols The disclosure describes novel precursors for the preparation of chiral 1,3-aminoalcohols. The precursors are chiral 4-hydroxycarboxamides, 4-hydroxyhydroxamic acids, or 4-hydroxyhydrazides produced from chiral gamma-lactones, which in turn are derived fr... | 03/27/2001 |
| 6172108 | Hydrazide compounds Compounds of formula (I): R--NH--A--CO--NH--NH--(W)n --Z (I) wherein: n is 0 or 1, W represents --CO-- or S(O)r wherein r is 0, 1 or 2, Z represents a group selected from aryl, arylalkyl, heteroaryl and heteroarylalkyl, each optionally substi... | 01/09/2001 |
| 6166257 | Asymmetric hydrogenation method of a ketonic compound and derivative The present invention relates to a process for the asymmetric hydrogenation of a ketonic compound and derivative. The invention relates to the use of optically active metal complexes as catalysts for the asymmetric hydrogenation of a ketonic compound and ... | 12/26/2000 |
| 6124356 | Fungicides A fungicidal compound of formula (I): or a stereoisomer thereof, wherein A is CH or N, B is OCH3 or NHCH3, E is --NR1 --C(CH3).dbd.N-- or --N.dbd.C(CH3)--NR1 --, R1 is H, C1... | 09/26/2000 |
| 6096890 | Process for substituted hydrazides using carboxylic acids This invention provides a convenient process for the preparation of monoacylhydrazines from carboxylic acids or their salts and hydrazine or substituted hydrazine in the presence of a 1,3,5-triazine substituted with at least one chloro or fluoro. The resu... | 08/01/2000 |
| 6046330 | Complexes of ultraviolet absorbers and quaternary ammonium compounds which are substantially free from unwanted salts This invention relates to complexes of ultraviolet absorbers with quaternary ammonium compounds which are substantially free from unwanted salts. Such complexes are formed through ionic bonds formed between the two compounds. The inventive complexes are t... | 04/04/2000 |
| 6043282 | Azinooximethers, processes and intermediate products for manufacturing same, and the uses thereof in combating harmful fungi and pests Azinooxime ethers of the formula I ##STR1## (X=NOCH3, CHOCH3, CHCH3 ; Y=O, NZ, where Z=H, alkyl; R1 =H, alkyl; R2 =cyano, nitro, trifluoromethyl, halogen, alkyl, alkoxy; m=0, 1, 2, it being possi... | 03/28/2000 |
| 6013836 | Insecticidal N'-substituted-N,N'-disubstitutedhydrazines This invention relates to N'-substituted-N,N'-disubstitutedhydrazines of formula I ##STR1## wherein X and X' are independently O, S, or NR; A' and B' are independently substituted or unsubstituted aryl or aromatic heterocycle; wherein F is alkyl... | 01/11/2000 |
| 5942644 | Precursors for the production of chiral vicinal aminoalcohols The disclosure describes new compositions of matter useful for the preparation of optically-active vicinal aminoalcohols. The compositions are chiral ଲ-hydroxycarboxamides, ଲ-hydroxyhydraxides, and ଲ-hydroxyhydroxamic acids.... | 08/24/1999 |
| 5767314 | Selective acylation of monoalkylhydrazines A process for selectively monoacylating monoalkylhydrazines by reacting such with trichloromethyl aryl ketones.... | 06/16/1998 |
| 5747535 | Selective thrombin inhibitors The present invention relates to a novel selective thrombin inhibitor having the following formula (I), which is also effective by oral administration: ##STR1## in which R1 represents acetyl substituted with aryl or aryloxy, or repres... | 05/05/1998 |
| 5700831 | Pesticidal hydrazide derivatives A compound of the formula ##STR1## wherein R is a) phenyl; phenyl(C1 -C4 alkoxy); phenoxy; or benzyl; the phenyl ring of each substituent being optionally substituted with one or more of halogen, nitro, C1 -C8 | 12/23/1997 |
| 5693860 | Amidrazones and their use as insecticidal and acaricidal agents There are provided substituted acid amide, arylhydrazone compounds (amaidrazones) of formula I ##STR1## the use thereof for the control of insect and acarid pests and methods and compositions for the protection of crops from the damage and loss cause... | 12/02/1997 |
| 5675037 | Selective acylation of hydrazines This application relates to a process for selectively monoacylating hydrazines by reacting unsubstituted or monoalkylhydrazines with trichloromethyl aryl ketones.... | 10/07/1997 |
| 5672723 | Process for preparation of 1-acyl-2-substituted hydrazines The present invention can provide a process for the preparation of an 1-acyl-2-substituted hydrazine compound from a mixture containing the 1-acyl-2-substituted hydrazine and an 1-acyl-1-substituted hydrazine by selective hydrolysis or alcoholysis of the ... | 09/30/1997 |
| 5543571 | Preparation of optically active hydrazines and amines A process for the asymmetric hydrogenation of N-acylhydrazones to optically active N-acylhydrazines in the presence of a chiral phospholane catalyst complex, a process for the reductive N--N bond cleavage of N-acylhydrazine to amines with samarium diiodid... | 08/06/1996 |
| 5541321 | Process for the preparation of a substituted diaminoalcohol A process is disclosed for the preparation of a substituted diaminoalcohol of the formula: ##STR1##... | 07/30/1996 |
| 5541320 | Process for the preparation of a substituted diaminoalcohol A process is disclosed for the preparation of a substituted diaminoalcohol of the formula: ##STR1##... | 07/30/1996 |
| 5523325 | Amidrazones and their use as pesticides This invention relates to amidrazones, insecticidal amidrazone compositions, and methods of using such compositions.... | 06/04/1996 |
| 5480871 | Peptoid -1 adrenergic receptor ligands Compounds of the formula: ##STR1## are useful for treating conditions modulated by 댑 -adrenergic receptors.... | 01/02/1996 |
| 5451607 | Hydrazone derivatives, process for producing same, insecticides and/or acaricides containing same as active ingredient and intermediate compounds thereof There are disclosed hydrazone derivatives of the general formula [I]: ##STR1## wherein R1 is halogen, etc.; R2 is hydrogen or C1 -C6 alkyl, etc.; R3 is hydrogen or C1 -C6 alkyl, ... | 09/19/1995 |
| 5447916 | Peptoid alpha-1 adrenergic receptor ligands Compounds of the formula: ##STR1## are useful for treating conditions modulated by 댑 -adrenergic receptors.... | 09/05/1995 |
| 5445888 | Hydrazine compound, process for the preparation of the same, and nonlinear optical organic material A novel hydrazine compound represented by the formula (I) is disclosed. ##STR1## Also disclosed are a process for preparing the novel hydrazine compound comprising reacting a specific hydrazine compound and a specific acid halide, a nonlinear optical... | 08/29/1995 |
| 5426223 | Preparation of optically active hydrazines and amines A process for the asymmetric hydrogenation of N-acylhydrazones to optically active N-acylhydrazines in the presence of a chiral phospholane catalyst complex, a process for the reductive N--N bond cleavage of N-acylhydrazine to amines with samarium diiodid... | 06/20/1995 |
| 5399758 | Diacylhydrazine photo-reactive compounds Disclosed are a novel azide compound represented, for example, by the formula, ##STR1## wherein Rf represents a fluoroalkyl or fluoroalkylpolyether group, ##STR2## wherein R represents a divalent organic group having an ester bond, an... | 03/21/1995 |
| 5358965 | Hydrazone derivatives, processes for production thereof, and uses thereof The present invention relates to a hydrazone derivative represented by the general formula (I) shown below: ##STR1## wherein the substituents are as defined in the specification, processes for preparing the derivative, and uses of the derivative as a... | 10/25/1994 |
| 5302744 | Phenolic-hydrazide compounds and polyolefin compositions stabilized therewith Disclosed are a class of phenolic-hydrazide compounds of diverse structure which are useful as stabilizers for polyolefins. The phenolic-hydrazide compounds inhibit oxidative degradation of polyolefins which is attributable to heat and/or ultraviolet ligh... | 04/12/1994 |
| 5300676 | Herbicidal fluorine-substituted alpha-(5-aryloxynaphthalen-1-yl-oxy)-propionic acid derivatives Fluorine-substituted -(5-aryloxy-naphthalen-1-yl-oxy)-propionic derivatives of the formula ##STR1## wherein R1, R2, R3, R4 and R5, as defined herein, are useful as herbicides. Processes an... | 04/05/1994 |
| 5294643 | Cinnamamide derivative Novel cinnamamide derivatives and the salts thereof are provided. An antihyperlipidemic composition is also provided. The composition comprises an active ingredient which is at least one selected from the group consisting of the above-mentioned cinnamamid... | 03/15/1994 |
| 5250731 | Preparation of optically active hydrazines and amines A process for the asymmetric hydrogenation of N-acylhydrazones to optically active N-acylhydrazines in the presence of a chiral phospholane catalyst complex, a process for the reductive N--N bond cleavage of N-acylhydrazine to amines with samarium diiodid... | 10/05/1993 |
