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Class 564/15 - Phosphorus attached indirectly to amino nitrogen by nonionic bonding


Subclass of Class 564 - Organic compounds -- part of the class 532-570 series
Definition: Compounds which contain phosphorus indirectly attached to
No. of patents: 144
Last issue date: 05/25/2010


1        
NumberTitleIssue Date
7723542Process for the preparation of alkyl- and aryl-diphosphonic acids and salts thereof
The invention relates to a process for the preparation of diphosphonic acids by reaction of a carboxylic acid with a mixture of phosphorous acid and phosphorus oxychloride in defined molar ratios and in the absence of solvents. The invention further relates to iband...
05/25/2010
7511174Solid and crystalline ibandronic acid
Provided are novel crystalline and amorphous forms of ibandronic acid, methods for their preparation, and pharmaceutical compositions containing them. Also provided are methods for purifying and assaying ibandronic acid in any crystalline form (or amorphous). ...
03/31/2009
7462739Ceramide derivatives, method for preparing the same, and therapeutic agent for treating atopic dermatitis comprising the ceramide derivatives
Disclosed are ceramide derivatives represented by the following formula 1 or 2, a method for preparing the same, and a therapeutic agent for treating atopic dermatitis including the ceramide derivatives as active ingredients: ...
12/09/2008
7417164Fluorescent dyes for use in glucose sensing
A novel class of compounds that includes HPTS-Cys-MA, and methods of making them are disclosed herein. The class of compounds including HPTS-Cys-MA are useful as fluorescent dyes for analyte detection. ...
08/26/2008
7414151Process for manufacture of 4-amino-hydroxybutylidene-1, 1-bisphosphonic acid and its salts
The preset invention relates to a cost effective, high yielding, reproducible method for the manufacture of alendronic acid or its salt, such as sodium alendronate, from inexpensive and readily available pyrrolidone using phosphonating agents such as PCl3
08/19/2008
7381745Ligands for metabotropic glutamate receptors and inhibitors of NAALADase
The present invention relates to novel compounds and formulations thereof which compounds are ligands, e.g., agonists or antagonists, for a metabotropic glutamate receptor or a NAALADase enzyme or both. The present invention also relates to methods of modulating the...
06/03/2008
7250535Process for producing tertiary phosphine
A production process by which tertiary phosphine with an attached sterically bulky hydrocarbon group is produced in a high yield and with high purity on an industrial scale through simple and safe operations by allowing a dialkylphosphinous halide to react with a Gr...
07/31/2007
7247731Ligands for metals and improved metal-catalyzed processes based thereon
One aspect of the present invention relates to novel ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom and carbon-carbon bond-forming react...
07/24/2007
7169817Bis-aromatic alkanols
The present invention relates to biphenylyl derivatives, processes for their production, their uses and pharmaceutical compositions containing them. Compounds according to the present invention are based upon the chemical formula:
01/30/2007
7148176Production of novel phosphane ligands and use in catalytical reactions
The present invention is directed to phosphine ligands and the use of such ligands in catalytic complexes with transition metals. The catalysts may be used in a variety of reactions and are especially useful for refining halogenoaromatics. ...
12/12/2006
7148382Bathochromic mono- and bis-acylphosphine oxides and sulfides and their use as photoinitiators
Compounds of formula (I), wherein A is S or O; x is 0 or 1; a is SR10 or N(R11)(R12); R1 and R2 are C1–C24alkyl, OR10, CF3 or halogen; R3, R4 a...
12/12/2006
7067701Preparation of phosphorus-containing compounds useful in the preparation of biphosphine ligands
This invention relates to processes for making phosphorus compounds R2P—X—PR2, R2P-M, R2P-L and R3P, and the novel cation R2P+(L)-X—P+(L)R2, where R represents a...
06/27/2006
7064231Optically active diamines and their use in catalytic processes
The invention relates to stereoisomerically enriched diamines, to metal complexes comprising these diamines and also to their use in a process for asymmetrically reducing ketones using silanes, in particular polymethylhydrosiloxane, as reducing agents. ...
06/20/2006
7038083Process for making bisphosphonic acids using diluents other than halogenated hydrocarbons
Provided is a novel method of making bisphosphonic acids, e.g. risedronic acid, including the step of combining a carboxylic acid, phoshorous acid, and a halophosphorous compound in the presence of a diluent that is an aromatic hydrocarbon or a silicone fluid. When ...
05/02/2006
7034015Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ...
04/25/2006
7012148Compositions and methods for thionation during chemical synthesis reactions
Compositions and methods for using these compositions to produce high yields of thionated compounds are provided. ...
03/14/2006
7001922Peptide deformylase activated prodrugs
The invention provides compounds and methods for using them to inhibit the growth of microorganism that expresses Peptide Deformylase, the compounds having the general formula: ...
02/21/2006
6967256Formation of enediynes by reductive coupling followed by alkyne metathesis
One aspect of the present invention relates to methods of preparing enedialkylidyne complexes, enediynes, and alkyne metathesis catalysts, as well as methods of catalyzing alkyne metathesis reactions. The present invention also relates to methods of activating enedi...
11/22/2005
6963008Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof
New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturing them, ar...
11/08/2005
6936700Bridged aromatic substituted amine ligands with donor atoms
The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hyd...
08/30/2005
6924389Method for producing diphosphines and the use thereof
Diphosphine of formula I R1R2P—H2C—Ar—CH2PR1R2  (I) are prepared by a process that comprises a) reacting a dimethyl compound of formula II H3C—Arâ€...
08/02/2005
6906212Phosphine-phosphoramidite compounds
Disclosed are novel phosphine-phosphoramidite compounds which may be employed in combination with a catalytically-active metal to effect a wide variety of reactions such as asymmetric hydrogenations, asymmetric reductions, asymmetric hydroborations, asymmetric olefi...
06/14/2005
6855849Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation
Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed comp...
02/15/2005
6699851Cytotoxic compounds and their use
Novel amides of polyunsaturated fatty acids with cysteamine-S-phosphate have been synthesized. Combinations of the all-trans-retinoic acid and/or amides of the 13-cis-retinoic acid with O-phospho-L-tyrosine, and N-docosahexaenoyl-cysteamine-S-phosphate, ...
03/02/2004
6693210Triphenylphosphine derivative, production process therefor, palladium complex thereof, and process for producing biaryl derivative
Provided are a novel triphenyl phosphine derivative synthesized from a triphenylphosphine and a hydroxy-containing lactone; a palladium and a nickel complexes comprising the derivative as a ligand; and a process for preparing a biaryl derivative using the...
02/17/2004
6657081Calixarene derivatives
The invention relates to new calixarenes according to the formula: ##STR1## wherein: R1 is an alkyl or aryl group, or a hydrogen atom, R2 and R3, which may be identical or different, are alkyl or aryl groups, n is a...
12/02/2003
6646079Multimodal polymers by controlled radical polymerization in the presence of alkoxyamines
For the preparation of a multimodal polymer at least one monomer is subjected to free radical polymerization in the presence of several alkoxyamines comprising the sequence of formula: ##STR1## in which RL is a monovalent radical exhibiting a m...
11/11/2003
6630501Phosphinic pseudo-peptides that may be used as matrix zinc metalloprotease inhibitors
The invention relates to pseudo-peptides according to the formula: ##STR1## wherein R1 is a group inhibiting an amine function, or an amino acid residue or peptide with an inhibited terminal amino function, R2 represents the later...
10/07/2003
6613848Phosphorus-containing phenolic, thiophenolic or aminophenyl flame-retardant hardener, and epoxy resins cured thereby
A hardener for an epoxy resin comprises a phenolic, thiophenolic, aminophenyl, tris-phenolic, tris-thiophenolic, tris-aminophenyl, tetrakis-phenolic, tetrakis-thiophenolic, or tetrakis-aminophenyl compounds; or phenol-formaldehyde or phenol-formaldeh...
09/02/2003
6569967Alkoxyamines derived from ଲ-phosphorous nitroxides
The invention concerns alkoxyamines derived from ଲ-phosphorous nitroxides corresponding to formula (I). Said compounds can be used as (co)polymerization initiators of at least a monomer polymerizable by radical polymerization. ##STR1##...
05/27/2003
6555227Latent combination compounds and latent ammonium salts comprising epoxide resin curing agents and flame-protection agents as well as epoxide resin systems and products prepared from them
Combination compounds from curing agents/accelerators and flame-protection agents for the latent curing/acceleration of epoxide resin systems and their endowment with flame-retarding properties, the epoxide resin systems being able to be thermally cured, ...
04/29/2003
6548567Ionic compounds with delocalized anionic charge, and their use as ion conducting components or as catalysts
The invention relates to an ionic compound corresponding to the formula [R1 X1 (Z1)--Q- --X2 (Z2)--R2 ]m Mm+ in which Mm+ is a cation of valency m, ea...
04/15/2003
6538141Method for preparing nitroxides
The invention concerns a method for preparing nitroxides, which consists in oxidising, in a two-phase medium, using an aliphatic peroxide, secondary amines with steric hindrance or having a --CH in the nitrogen atom ଱....
03/25/2003
6509100Fluorinated hydrogn bond stabilized surface modifying agents, articles made therefrom, methods for making and using the same
The present invention discloses hydrogen bond stabilized surface modifying agents having a fluorinated or semi-fluorinated carbon-containing tail group, an internal moiety capable of intermolecular hydrogen bonding or related acid-base interactions and a ...
01/21/2003
6506934Water soluble halogen-containing compounds
This invention relates to a compound that is represented by the following Structure I: R1 --SO2 --C(R2)R3 --(CO)m --(L)n --SG I wherein R1 is an aliphatic or cyclic group, R2 a...
01/14/2003
6486347Preparation of phosphine ligands
A process for the preparation of a compound having the formula R3 R4 P--Ar--CO--X wherein Ar is an aryl group bearing the PR3 R4 and COX groups in a 1,2-relationship, and optionally bearing also one or more non-inter...
11/26/2002
6413947Anilide derivative, production and use thereof
This invention is to provide a compound of the formula: ##STR1## wherein R1 is an optionally substituted 5- to 6-membered ring; W is a divalent group of the formula: ##STR2## wherein the ring A is an optionally substituted 5- to 6-membered arom...
07/02/2002
6395916Ligands for metals and improved metal-catalyzed processes based thereon
One aspect of the present invention relates to novel, electron-rich bidentate ligands for transition metals. A second aspect of the present invention relates to the use of catalysts comprising these ligands in transition metal-catalyzed carbon-heteroatom ...
05/28/2002
6388130Method for producing axial asymmetric compounds, and intermediates for producing the same
The invention provides a metal complex comprising a ligand and a metal. The ligand is an aminophosphine compound represented by the following formula (1) ##STR1## The metal is rhodium, ruthenium, iridium or nickel....
05/14/2002
6307098Water soluble phosphines
This invention relates to water soluble phosphines of the following structural formula and method of preparing these phosphines: ##STR1## Wherein A is a moiety which is stable to the reaction conditions and does not interfere with solubility of the compou...
10/23/2001
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