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| Number | Title | Issue Date |
| 8278483 | Process for synthesis of glycomimicking cationic amphiphiles The present invention provides processes for the synthesis of novel Shikimic acid head-group containing non-toxic cationic amphiphiles capable of facilitating transport of biological macromolecules into cells. ... | 10/02/2012 |
| 8183413 | Process for production of β-amino-α-hydroxy carboxamide derivative Provided is a process for production of a β-amino-α-hydroxy carboxamide derivative that is important in production of drugs or the like. In the presence of a predetermined solvent, a β-(N-protected)amino-α-hydroxycarboxylic acid is reacted with an amine to conve... | 05/22/2012 |
| 8158826 | Continuous process for the production of mono- or dicarboxylic acid alkyl amides A continuous process for the production of mono- or dicarboxylic acid alkyl amides is described, which is characterized in that: fresh mono- or dicarboxylic acid is placed into a first reactor (R1) connected with a distillation column (C1) and subjecte... | 04/17/2012 |
| 7745661 | Process for producing tricarboxylic acid tris (alkyl-substituted cyclohexylamide) Disclosed are, for example, a process for producing a tricarboxylic acid tris(alkyl-substituted cyclohexylamide), the process comprising subjecting a tricarboxylic acid and an alkyl-substituted cyclohexylamine to an amidation reaction, either (a) in the presence of ... | 06/29/2010 |
| 7696379 | Acetylene derivatives The invention provides compounds of formula (I) wherein R1 represents hydrogen or alkyl; R2 represents an unsubstituted or substituted heterocycle or R2 | 04/13/2010 |
| 7667076 | Amide forming chemical ligation An amide is formed by reacting an α-ketoacid or salt thereof in a decarboxylative condensation reaction with an amine or salt thereof comprising a nitrogen covalently bound to an atom selected from oxygen, nitrogen, and sulfur. The amide bond is formed between the ... | 02/23/2010 |
| 7439394 | Cyclohexyl-1,4-diamine compounds Novel cyclohexyl-1,4-diamine compounds corresponding to formula I, processes for the production thereof, pharmaceutical compositions containing these compounds, methods of producing pharmaceutical compositions including the... | 10/21/2008 |
| 7390923 | Propionamide derivatives useful as androgen receptor modulators Compounds of formula (I) wherein R1 to R4, X and A are as defined in the claims and pharmaceutically acceptable salts and esters thereof, are disclosed. The compounds of formula (I) possess utility as tissue-selective andro... | 06/24/2008 |
| 7329780 | Method of preparing optically pure phenethylamine derivatives Provided is a method of preparing an optically pure compound having formula 1 or its salts. The method includes: reacting (R)-2-(4-methoxy-3-aminosulfonyl-phenyl)-1 -methylethylamine or its salts with a compound selected from the group consisting of chloroacetic aci... | 02/12/2008 |
| 7288619 | Fluorinated polyether polyamine and method of making the same A composition comprises a condensation product of an amine-reactive fluorinated polyether and a polyamine. The compositions may be in dispersed in water. ... | 10/30/2007 |
| 7273942 | Water-soluble group III polyether acid salt complexes and thin films from same A water-stable and water-soluble ceramic precursor is provided, containing at least one Group III element. Also, a metal acid salt complex is provided comprising (1) bismuth, lanthanum, and titanium, and (2) a polyether acid. In addition, methods are provided for pr... | 09/25/2007 |
| 7208540 | Process for curing aminoplast resins Aminoplast resins are cured using inorganic particles as curing agents. The inorganic particles have a laminated structure and include interlamellarly exchangeable cations such as alkali cations, alkaline-earth cations, aluminum cations, iron cations and/or manganes... | 04/24/2007 |
| 7189873 | Propargylether derivatives, a process for their preparation and their use for controlling phytopathogenic microorganisms The invention relates to 4-propargyloxy-benzyl dervatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl or optionally ... | 03/13/2007 |
| 7019149 | Thromboxane ligands without blood clotting side effects A method of treating ocular hypotension, hypertension, hemorrhage, myocardial ischemia, angina pectoris, coronary contraction, cerebrovascular contraction after subarachnoidal hemorrhage, cerebral hemorrhage and asthma which comprises administering to a mammal suffe... | 03/28/2006 |
| 6995284 | Synthesis of selective androgen receptor modulators The present invention relates to a synthetic process for the preparation of a novel class of androgen receptor targeting agents (ARTA) which demonstrate androgenic and anabolic activity of a nonsteroidal ligand for the androgen receptor. The agents define a new subc... | 02/07/2006 |
| 6965048 | Hydroxyalkylamide derivatives The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, X, W, m and n are as defined hereinabove. The compounds are useful for the treatment and/or ... | 11/15/2005 |
| 6960688 | Use of compounds for the elevation of pyruvate dehydrogenase activity The use of compounds of formula (I), and salts thereof; and pharmaceutically acceptable in vivo cleavable prodrugs of said compound of formula (I); and pharmaceutically acceptable salts of said compound or said prodrugs; in formula (I), Ring C is phenyl or a carbon ... | 11/01/2005 |
| 6946025 | Process for preparing tetra-amide compounds Disclosed is a process for preparing a tetra-amide which comprises carrying out a condensation reaction between a diacid, a monoacid, and a diisocyanate, thereby forming a tetra-amide. Also disclosed is a process for preparing a phase change ink composition which co... | 09/20/2005 |
| 6918958 | Acid pigment dispersants and pigment preparations The invention relates to pigment dispersants of the formula (I), and to pigment preparations including at least one organic pigment and at least one pigment disperant of the formula (I): wherein Q1, R1 | 07/19/2005 |
| 6900354 | 3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives The invention relates to 3-phenyl-propionamido, 3-phenyl-acrylamido and 3-phenyl-propynamido derivatives, for example, deriviatives of the formula wherein A is selected from | 05/31/2005 |
| 6864392 | α-Sulfin and α-Sulfonamino amide derivatives The invention relates to novel pesticidally active α-sulfin- and α-sulfonamino acid amides of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein n is a number zero or one, R1-R7 have the meanin... | 03/08/2005 |
| 6515153 | Process for forming amido esters utilizing a spinning disc reactor The present invention relates to the formation of an amido ester having the formula: R1 --CO--NR3 --R2 --COL or R1 --NR3 --CO--R2 --COL wherein R1 is C1 -C12 linear o... | 02/04/2003 |
| 6515175 | Mono-and polyamides of perfluoroalkyl-substituted unsaturated acids Novel perfluoroalkyl-substituted mono-, di- and poly-amide compounds which are reaction products of a mono-, di- or polyamine of 60 to 2000 molecular weight with a perfluoroalkyl substituted unsaturated acid or its corresponding lower alkyl ester and opti... | 02/04/2003 |
| 6504057 | Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them This invention relates to fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them. An embodiment of the invention embraces compounds of the formula ... | 01/07/2003 |
| 6498275 | Use of compounds for the elevation of pyruvate dehydrogenase activity The use of compounds of the formula (I), and salts thereof; and pharmaceutically acceptable in vivo cleavable prodrugs of said compound of formula (I); and pharmaceutically acceptable salts of said compound or said prodrugs: ##STR1## wherein: Ring C ... | 12/24/2002 |
| 6498274 | Amide derivatives for the treatment of diseases mediated by cytokines The invention concerns the use of amide derivatives of formula (I) wherein: R1 and R2 are substituents such as hydroxy, C1-6 alkoxy, mercapto, C1-6 alkylthio, amino, C1-6 alkylamino and di-(C1-6 | 12/24/2002 |
| 6458948 | Process for producing carboxylic acid derivative and condensing agent comprising quaternary ammonium salt A method of preparing carboxylic acid derivatives comprising mixing a quaternary ammonium salt having a particular triazine ring in the molecules thereof, a carboxylic acid compound and a compound having a nucleophilic functional group, to condense the ca... | 10/01/2002 |
| 6452051 | Process for the production of a condensation products of a carboxylic acid The invention provides a process for the production of a condensation product selected from the group consisting of an amide and an ester of a carboxylic acid from an organic compound selected from the group consisting of organic compounds carrying a hydr... | 09/17/2002 |
| 6441043 | Glyoxylic acid amides The invention relates to novel glyoxylic acid amides, to a plurality of processes for their preparation and to their use for controlliing pests.... | 08/27/2002 |
| 6399825 | Process for manufacture of dimethyl acetamide A process for the increasing the conversion of raw materials into DMAc by increasing the temperature at which the reaction occurs. The higher temperature is achieved by installing a pressure control valve in the dimethyl amine recycle line returning to th... | 06/04/2002 |
| 6384278 | Boron-mediated amidation of carboxylic acids The present invention provides an inexpensive one-step method for preparing an aromatic carboxamide, such as a phenyl substituted carboxamide) by reacting an aromatic amine (e.g. a phenylamine) and a carboxylic acid (e.g. an alkanoic acid or ester thereof... | 05/07/2002 |
| 6369273 | Chemical compounds and their use to elevate pyruvate dehydrogenase activity The use of a compound of the formula (I): ##STR1## wherein: ring C is phenyl or carbon-linked heteroaryl selected from pyridyl, pyrazinyl, pyrimidinyl and pyridazinyl; and wherein said phenyl or heteroaryl is substituted as defined herein; A--B is selecte... | 04/09/2002 |
| 6335468 | Process for production N-acyl amino acid amide There is provided a process for producing an N-acyl amino acid amide, comprising a condensation reaction of an N-acyl amino acid with an amine and/or an ammonia, preferably a primary amine, a secondary amine and/or an ammonia under dehydration in the pres... | 01/01/2002 |
| 6291712 | Process for producing saturated aliphatic carboxylic acid amide A process for producing a saturated aliphatic carboxylic acid amide, comprising reacting a saturated aliphatic carboxylic acid with ammonia to thereby obtain a saturated aliphatic ammonium carboxylate and subjecting the saturated aliphatic ammonium carbox... | 09/18/2001 |
| 6235789 | Benzocycloalkene compounds, their production and use A compound of the formula ##STR1## wherein R1 and R2 are H, a hydrocarbon group or a heterocyclic group, or R1 and R2 are combinedly a spiro ring; R3 is a hydrocarbon group, a substituted amino group,... | 05/22/2001 |
| 6215024 | Process for the production of amides from amines The present invention provides a novel single step process for the production of amides from amines comprising reaction of amines with an acylating agent comprising of a carboxylic acid in a molar ratio of 1:3 to 1:10 in the presence of reusable natural m... | 04/10/2001 |
| 6211409 | Process for preparing mono-, Di- or oligoamide alkoxylates A process is disclosed for preparing di- or oligoamide alkoxylates. Diamides are prepared from carboxylic acids or carboxylic acid alkyl esters and di-, oligo-, or polyamines and are alkoxylated as a melt directly after their preparation, without any furt... | 04/03/2001 |
| 6207861 | Method for producing and screening mass coded combinatorial libraries for drug discovery and target validation The present invention provides a method for producing a mass-coded combinatorial library comprising a set of compounds having the general formula X(Y)n, where X is a scaffold, each Y is, independently, a peripheral moiety, and n is an integer g... | 03/27/2001 |
| 6177594 | 4-(4-oxocyclohexyl) benzamides as intermediate products for medicaments Benzamides of the formula I: ##STR1## wherein R1 and R2 independently of one another are each alkyl having 1-6 C atoms, or R1 and R2 together are alkylene, and their salts, are suitable as intermediates in the synthe... | 01/23/2001 |
| 6130315 | Peptidase inhibitors This invention relates to analogs of peptidase substrates in which the amide group containing the scissile amide bond of the substrate peptide has been replaced by an activated electrophilic ketone moiety. These analogs of the peptidase substrates provide... | 10/10/2000 |
