"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
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| Number | Title | Issue Date |
| 8034976 | Nitrogen-containing carbon material and method of producing the same The present invention provides a nitrogen-containing carbon material characterized in that it satisfies a specific relational expression between the number ratio of nitrogen atoms to carbon atoms and the number ratio of hydrogen atoms to carbon atoms and has peaks i... | 10/11/2011 |
| 7816560 | Long chain n-alkyl compounds and oxa-derivatives thereof Long chain N-alkyl amino and imino compounds, oxa-substituted derivatives thereof, and pharmaceutical compositions including such compounds are described. The long chain N-alkyl group is a C8-C16 alkyl group. The long chain N-alkyl compounds an... | 10/19/2010 |
| 7329427 | Process for producing γ-hydroxyamino acid derivatives and monatins Dihydroisoxazole derivatives are conveniently converted to γ-hydroxyamino acid derivatives which are important as various synthetic intermediates by a catalytic hydrogenation reaction. High-purity monatins which may be used as sweeteners or ingredients thereof can ... | 02/12/2008 |
| 7301018 | Probe for mass spectrometry of liquid sample Disclosed is a probe for mass spectrometry of liquid samples, which may effectively ionize the sample without adding a protic solvent to the mobile phase in the ionization method in mass spectrometry of liquid samples. The probe according to the present invention ha... | 11/27/2007 |
| 7232927 | Preparation of mono-N-sulphonylated diamines The present invention relates to a process for preparing mono-N-sulphonylated diamines by reacting diamines with sulphonyl halides in the presence of water, base and organic solvents. ... | 06/19/2007 |
| 7229981 | Process for the preparation of aminoalcohol derivatives and their further conversion to (1R,4S)-4-(2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl-1-methanol The invention relates to a novel process for the preparation of an aminoalcohol of the formula racemically or optically active, starting from 2-azabi-cyclo[2.2.1]hept-5-en-3-one, its further conversion to give th... | 06/12/2007 |
| 7205440 | Method of producing amines The invention relates to a special two-step method for producing amines on the basis of amides by reacting them with halides or hypohalites in an aqueous solution in a Hofmann degradation reaction. The amide is reacted in an alkaline solution and/or suspension with ... | 04/17/2007 |
| 7157399 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or mo... | 01/02/2007 |
| 7018840 | Fluorescent metal sensors, and methods of making and using the same The present invention is directed, in part, to fluorescent metal sensors for detecting metal ions, and methods of making and using the same. ... | 03/28/2006 |
| 7002053 | Method for preparing high-purity diisobutene The invention relates to a process for preparing high-purity diisobutene by reaction of isobutene or isobutene-containing hydrocarbon mixtures over a solid acidic ion-exchange resin containing sulfonic acid groups whose protons have been partly replaced by metal ion... | 02/21/2006 |
| 6963008 | Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturing them, ar... | 11/08/2005 |
| 6960691 | Production process for halogenated aromatic methylamine The invention intends to provide means for producing halogenated aromatic methylamine useful as an intermediate in the production of agrochemical or medical preparations, by an industrially advantageous method. The process according to the present invention f... | 11/01/2005 |
| 6949681 | Intermediate for preparing glycopeptide derivatives This invention provides compounds of the formula: wherein A and B are as defined; and Fmoc is 9-fluorenylmethoxycarbonyl. Such compounds are useful as intermediates for preparing glycopeptide d... | 09/27/2005 |
| 6924315 | Gemini glycidyl ether adducts of polyhydroxyalkyl alkylenediamines The present invention provides compounds useful as surfactants having formula (1), including isomers thereof: wherein a and b are integers independently selected from about 3 to about 6; x is an integer from about 1 to... | 08/02/2005 |
| 6919481 | Alkoxyamines containing a vinyl group, their applications and methods of their production Alkoxyamines containing a vinyl group as represented by the following general formula (1) are produced in a method which comprises a process of heating divinyl benzene, nitroxide compound and organic peroxide up to a temperature at which the organic peroxide decompo... | 07/19/2005 |
| 6777512 | Amine organoborane complex initiated polymerizable compositions containing siloxane polymerizable components In one embodiment the invention is a polymerizable composition comprising a) an organoborane amine complex; b) one or more of monomers, oligomers or polymers having olefinic unsaturation which is capable of polymerization by free radical polymerization; c) one or mo... | 08/17/2004 |
| 6730759 | Amine organoborane complex polymerization initiators and polymerizable compositions The invention is polymerizable composition comprising a) an organoborane/amine complex wherein the organoborane is a trialkyl borane or an alkyl cycloalkyl borane and the amine is selected from the group of amines having an amidine structural component; aliph... | 05/04/2004 |
| 6713579 | Amine organoborane complex polymerization initiators and polymerizable compositions A method of modifying the surface of a low surface energy polymer by contacting the surface with a composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic hetero... | 03/30/2004 |
| 6713578 | Amine organoborane complex polymerization initiators and polymerizable compositions A method of bonding two or more substrates together which comprises I. contacting the components of the composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural componen... | 03/30/2004 |
| 6710145 | Amine organoborane complex polymerization initiators and polymerizable compositions A method of coating a substrate which comprises coating a substrate with the composition comprising a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic heterocycles having a... | 03/23/2004 |
| 6706831 | Amine organoborane complex polymerization initiators and polymerizable compositions The invention is a method of polymerization comprising contacting the components of the polymerizable composition of a) an organoborane/amine complex wherein the amine is selected from the group of amines having an amidine structural component; aliphatic hete... | 03/16/2004 |
| 6632895 | Functionalized alkoxyamine initiators The invention relates to a new process for the preparation of functionalized alkoxyamine initiators, new alkoxyamine initiators based on (meth)acrylate which are prepared by this process, and their use for the preparation of polymers.... | 10/14/2003 |
| 6566468 | Nitroxyl derivatives with glycidyl or alkylcarbonyl groups as initiators for radical polymerization Glycidyl and alkylcarbonyl functional nitroxide radical polymerization initiator compounds of formula (Ia) or (Ib), ##STR1## where R1, R2 and A are as defined within, R3 is a radical of formula (II) ##STR2## where X is ph... | 05/20/2003 |
| 6555140 | Composition and method for enhancing male fertility and libido A composition for enhancing the fertility and/or libido of a male mammal is described as well as methods of enhancing fertility and libido. The composition described includes the polyamines spermine, spermidine and according to one embodiment also include... | 04/29/2003 |
| 6521780 | Cycloalkyl derivatives and the solid-phase synthesis of such derivatives The invention relates to cycloalkyl derivatives, a process for their preparation and their use.... | 02/18/2003 |
| 6518245 | Treatment of arrhythmias via inhibition of a multifunctional calcium/calmodulin-dependent protein kinase This invention provides a method for treating or preventing arrhythmias in a human subject comprising the administration of an effective amount of a calcium/calmodulin-dependent protein kinase inhibitor. Also provided are pharmaceutical compositions compr... | 02/11/2003 |
| 6448402 | Process for the preparation of aminoalcohol derivatives and their further conversion to (1R, 4S)-4-((2-amino-6-chloro-5-formamido-4-pyrimidinyl)-amino)-2-cyclopentenyl -1-methanol The invention relates to a novel process for the preparation of an aminoalcohol of the formula ##STR1## racemically or optically active, starting from 2-azabicyclo[2.2.1]hept-5-en-3-one, its further conversion to give the corresponding acyl derivativ... | 09/10/2002 |
| 6384165 | Organoborane amine complex initiator systems and polymerizable compositions made therewith A composition comprises organoborane amine complex and 1,4-dioxo-2-butene-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The s... | 05/07/2002 |
| 6359061 | Amide compound libraries Amide compounds of formula (I), combinatorial libraries of amide compounds and methods of preparing the same are provided. Libraries of the invention are useful for screening in biological assays in order to identify pharmaceutically useful compounds. ... | 03/19/2002 |
| 6340772 | Process for preparing (hetero) aromatic substituted benzene derivatives Three processes are described for preparing (hetero)aromatic substituted benzene derivatives which comprise aromatization of cyclohexenone derivatives via (chloro)cyclohexadiene derivatives.... | 01/22/2002 |
| 6291702 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 09/18/2001 |
| 6271418 | Process for preparing (hetero) aromatic substituted benzene derivatives Three processes are described for preparing (hetero)aromatic substituted benzene derivatives which comprise aromatization of cyclohexenone derivatives via (chloro)cyclohexadiene derivatives.... | 08/07/2001 |
| 6252023 | Organoborane amine complex inatator systems and polymerizable compositions made therewith A composition comprises organoborane amine complex and 1,4-dioxo-2-butene-functional material. The composition can form a part of a polymerization initiator system that also includes a compound that is reactive with the amine portion of the complex. The s... | 06/26/2001 |
| 6197825 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 03/06/2001 |
| 6132985 | Methods for the detoxification of nitrile and/or amide compounds The present invention describes methods for the detoxification of a mixture of nitrile compounds, or a mixture of nitrile and amide compounds by conversion of the nitrile compound(s) to the corresponding amide or acid compounds using a pure culture of an ... | 10/17/2000 |
| 5929232 | Stereoselective ring opening reactions The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic chiral catalyst to produce a s... | 07/27/1999 |
| 5866354 | Method for measuring mobility of sperm A method of identifying highly fecund males in which an isotonic, buffered liquid test specimen of semen is layered on top of a barrier medium that inhibits net movement (migration) of less mobile sperm into the barrier medium. Differences in mobility of ... | 02/02/1999 |
| 5863750 | Methods for the detoxification of nitrile and/or amide compounds The present invention describes methods for the detoxification of a mixture of nitrile compounds, or a mixture of nitrile and amide compounds by conversion of the nitrile compound(s) to the corresponding amide or acid compounds using a pure culture of an ... | 01/26/1999 |
| 5854409 | Pro-thiol aryl azide labelling of nucleic acids Reagents and methods for multi-step labeling of nucleic acids allow the addition of relatively insoluble or unstable labels to nucleic acid in the final step. Nucleic acids can be stored as a stable intermediate capable of reacting with a label conjugated... | 12/29/1998 |
| 5814664 | 3-alkylamino-2-hydroxy-4-hydroxymethyl-2-cyclopenten-1-one advanced glycosylation endproducts and methods of use therefor The present invention relates to advanced glycosylation endproducts, and particularly to the use of novel cyclopentenone aminoreductones, 3-alkylamino-2 -hydroxy-4-hydroxymethyl-2-cyclopenten-1-ones. Such AGEs can be used in various diagnostic and therape... | 09/29/1998 |