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| Number | Title | Issue Date |
| 7473803 | Process for production of optically active 2-halogeno-carboxylic acids The invention provides processes for producing efficiently optically active 2-halogenocarboxylic acids useful in the preparation of drugs or the like and salts thereof with amines. Specifically, an optically active 2-halogenocarboxylic acid is produced by halogenati... | 01/06/2009 |
| 7253315 | Process for preparing fluorocarboxylic acids A fluorocarboxylic acid preparation process which includes hydrolyzing fluorocarboxylic acid fluoride in the presence of an aqueous sulfuric acid solution to form a reaction product containing a fluorocarboxylic acid and hydrogen fluoride (present as hydrofluoric ac... | 08/07/2007 |
| 7217409 | Alkanoic acid derivatives A method for treating respiratory disorders comprises administering to a patient a pharmaceutical aerosol formulation comprising: (i) a compound of formula (I) or a salt or solvate thereo... | 05/15/2007 |
| 7094926 | Process for producing optically active carboxylic acid substituted in 2-position A nitrous acid salt is added at a temperature of 10 to 80° C. to an aqueous solution which contains an optically active 2-aminocarboxylic acid (4) and a protonic acid, the amount of the latter acid being 1 to 3 equivalents to the former, and which has a proton conc... | 08/22/2006 |
| 7015349 | Reduction of hair growth Compositions including a conjugate of α-difluoromethylornithine can be applied topically to reduce hair growth. ... | 03/21/2006 |
| 6969576 | Photosensitive dissolution inhibitors and resists based on onium salt carboxylates A photoresist composition that employs onium salt carboxylates as thermally stable dissolution inhibitors. The photoresist composition can be either an onium carboxylate salt with a phenolic photoresist, such as novolac, or an onium cation protected carboxylate-cont... | 11/29/2005 |
| 6846952 | Process for manufacture of a 4-bromo-2-oxyimino butyric acid and its derivatives A process for producing 4-bromo-2-oxyimino butyric acid, predominantly as the (Z)-isomer of formula (I), wherein R is hydrogen; a linear or branched C1-4 alkyl group; a linear or branched C1-4 alk... | 01/25/2005 |
| 6743929 | Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors Sulfonamide-containing hydroxyethylamine compounds are effecive as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. ... | 06/01/2004 |
| 6642415 | Method for recovering fluorinated emulsifiers Fluorinated emulsifiers, in particular, perfluorooctanoic acid are bound to anionic exchange resins for the purification of aqueous effluent from the production of fluoropolymers. Said emulsifiers may be quantitatively eluted from the exchanger with a wat... | 11/04/2003 |
| 6465686 | Halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors The present invention discloses halogenated 2-amino-5,6 heptenoic acid derivatives useful as nitric oxide synthase inhibitors.... | 10/15/2002 |
| 6288291 | Fluorination A process for fluorinating a hydrocarbon substrate by mixing it with an inert diluent and mixing the diluted substrate with a gaseous fluorinating reagent to form a foam reaction mixture. The fluorinating reagent reacts with the substrate in the form to f... | 09/11/2001 |
| 6184415 | Production of chiral non-racemic 2-halopropionic acid or salt thereof It has been discovered that it is possible to produce enantioselectively, a chiral 2-haloalkanoic acid or salt thereof, by subjecting a 2-halo-,ଲ-alkenoic acid or salt, e.g., a 2-haloacrylic acid or salt, to asymmetric hydrogenation in the pr... | 02/06/2001 |
| 6175024 | Synthesis of functionalized esters A method of preparing an ester of a carboxylic acid functionalized with a moiety selected from the group consisting of halides, sulfonates, ethers, hydroxyl, amines, and aldehydes, said method comprising: (a) providing either a carboxylic acid having a vi... | 01/16/2001 |
| 6046292 | Polymerizable mesophases based on substituted unsaturated carboxylic acids Mesogens are provided based on substituted unsaturated carboxylic acids such as acrylic and methacrylic acid. Substitution of a variety of hydrophobic tails onto the carboxylic acid or acid derivative via the vinyl carbon proximal to the carbonyl of the c... | 04/04/2000 |
| 5958979 | Stabilized medicaments containing thyroid hormones The present invention relates to stabilized medicaments containing thyroid hormone the stabilizing component of which is sodium thiosulfate in a mass ratio of thyroid hormone to sodium thiosulfate of 1:0.1 to 1:50 and processes for preparing such medicame... | 09/28/1999 |
| 5905127 | Polymerizable mesophases based on substituted unsaturated carboxylic acids Mesogens are provided based on substituted unsaturated carboxylic acids such as acrylic and methacrylic acid. Substitution of a variety of hydrophobic tails onto the carboxylic acid or acid derivative via the vinyl carbon proximal to the carbonyl of the c... | 05/18/1999 |
| 5852212 | Process for preparation of optically active -bromo and -chlorocarboxylic compounds Optically active -bromo- or -chlorocarboxylic compounds of the formula ##STR1## wherein X is bromine or chlorine; M is hydrogen, NR4+1 or a cation of an alkali or alkaline earth metal; R1 is hydrogen or ... | 12/22/1998 |
| 5763659 | Preparation of optically active 2-halopropionic acids The present invention relates to a process for the preparation of optically active 2--halopropionic acids, in which the corresponding optically active alkyl 2--halopropionates are caused to react with a carboxylic acid at elevated temperature in a transac... | 06/09/1998 |
| 5576459 | Quaternary nitrogen or phosphorus chirates An optically-active or chiral compound is described which comprises (A) at least one quaternary nitrogen or phosphorus cation provided that if the cation is a quaternary nitrogen cation containing a hydroxyalkyl group, the hydroxyalkyl group is free of chlorin... | 11/19/1996 |
| 5545298 | Process for preparing polyfluorocarboxylic acid chlorides and perfluorocarboxylic acid chlorides A process for preparing compounds corresponding to the formula RCFXC(O)Cl, in which X is fluorine or chlorine and R is fluorine or a perfluorinated C1- C10-alkyl group, preferably chlorodifluoroacetyl chloride, by photochemical oxidation of R122 (CF2... | 08/13/1996 |
| 5527951 | Polymerization catalyst and process Tert-alkylmethoxy-substituted vanadium compounds, several of which are novel, are useful as catalysts for the polymerization of ethylene or the copolymerization of ethylene with alphaolefins and (optionally) nonconjugated polyenes. Also disclosed is a nov... | 06/18/1996 |
| 5527954 | Process for the production of 2-fluoroisobutyric acid or its ester Provided is a process for the production of 2-fluoroisobutyric acid or its ester, which comprises reacting 2-hydroxyisobutyric acid or its ester with thionyl chloride and a hydrogen fluoride source.... | 06/18/1996 |
| 5475135 | Catalyst for the dehalogenation of -halogenated carboxylic acids The invention relates to a catalyst comprising a rare metal of Group VIII of the Periodic Table of Elements which has been deposited on an inert support and which has been used to dehalogenate -halogenated carboxylic acids in the presence of hydrog... | 12/12/1995 |
| 5442106 | Process for hydrolyzing esters using 4-aminopyridyl siloxane catalysts Described are preferred processes for hydrolyzing activated esters using, as catalysts, siloxanes having 4-dialkylaminopyridyl groups incorporated into their polymer backbones. The preferred siloxane catalyst materials demonstrate unexpected catalytic eff... | 08/15/1995 |
| 5426222 | Method for the preparation of iodonium salts The present invention relates to an improved method for the preparation of iodonium salts. More specifically, the present invention relates to an improved method for the production of symmetric or asymmetric diaryliodonium triflate (trifluoromethane sulfo... | 06/20/1995 |
| 5302757 | Ultraviolet light sensitive onium salts A composition of matter including an onium salt and a method of forming images. The onium salt has a chromophore which absorbs ultraviolet radiation, an S, Se, As, N or P atom which is free of substituents exhibiting a higher energy occupied molecular orb... | 04/12/1994 |
| 5292928 | Process for the reaction of a low-molecular hydroxyl compound with a carboxylic acid halide In a process for reacting a low molecular weight hydroxy compound with a carboxylic acid halide, a small amount of the acid halide is introduced into the reaction vessel and the remainder of the acid halide and the hydroxy compound are added gradually in ... | 03/08/1994 |
| 5258547 | Process for preparing halogenated compounds A process for preparing halogenated compounds of formula RCY(Z)CH2 CH(X)C(CH3)CH2 COR1 where X, Y and Z are halo, R is alkyl, halo, haloalkyl or aryl, and R1 is hydroxy, halo, alkoxy, alkyl or haloalk... | 11/02/1993 |
| 5215671 | Purification method of 2-chloropropionic acid The present invention is directed to a method for recovering 2-chloropropionic acid so that this compound can be separated in a high-purity form. According to the method, crude 2-chloropropionic acid is heat-treated in the presence of a metal compound at ... | 06/01/1993 |
| 5175345 | Process for producing 2-fluoroisobutyric acid ester A 2-fluoroisobutyric acid ester can be obtained at a high yield in one pot by reacting a 2-hydroxyisobutyric acid ester with fluorosulfuric acid in the absence or presence of a hydrogen fluoride source, or by reacting a 2-hydroxyisobutyric acid ester with... | 12/29/1992 |
| 5144067 | Process for the coproduction of alkyl iodides and alpha-iodocarboxylic acids and/or anhydrides thereof Disclosed is a process for the coproduction of (1) an alkyl iodide and (2) an -iodocarboxylic acid, a mono--iodocarboxylic anhydride or a mixture thereof which comprises contacting a mixture of an iodine compound and a carboxylic anhydride w... | 09/01/1992 |
| 5068405 | Famotidine intermediates and their preparation Halogenated N-sulfamyl propionamidine addition salts corresponding to the formula ##STR1## are provided, in which X represents halogen and A represents an acid selected from sulfuric acid, nitric acid, benzenesulfonic acid; toluenesulfonic acid;... | 11/26/1991 |
| 4888443 | Process for the production of pimelic acid A process for the production of pimelic acid comprising reacting &3xb5;-caprolactone with carbon monoxide and water in the presence of a carbonylation catalyst, such as a Group VIII metal and hydrogen halide.... | 12/19/1989 |
| 4845271 | Process for the preparation of omega-unsaturated carboxylic acids An improved method for the synthesis of omega-unsaturated carboxylic acids is disclosed which precludes double bond migration or hydrogenation in order to prepare a high purity product necessary for high resolution in forming a resist by electron beam mic... | 07/04/1989 |
| 4734511 | Method for producing ,-dimethyl-Ɗ-valerolactone A method for producing ,-dimethyl-δ-valerolactone which comprises carrying out the addition reaction of hydrogen bromide and 2,2-dimethyl-4-pentenoic acid in the presence or absence of a catalyst to synthesize 2,2-dimethyl-5-bromovaleric ac... | 03/29/1988 |
| 4670593 | Haloacetamidines and the herbicidal use thereof Dichloroacetamidines having the formula ##STR1## in which A and B are independently selected from hydrogen, fluorine, chlorine, bromine and methyl, provided that at least one of A or B is other than hydrogen; M is hydrogen or methyl; X is selected fr... | 06/02/1987 |
| 4628118 | 5,5-dichloro-3,3-dimethylpentanoic acid The following process steps are shown: ##STR1## Intermediates I, II and IV are new. End product III is known, useful as an intermediate in the manufacture of pesticides, pharmaceuticals and dyestuffs.... | 12/09/1986 |
| 4613690 | Racemization of optically active compounds having a bromine substituted chiral carbon atom Optically active compounds having a chlorine atom attached to the chiral carbon atom such as 2-bromoaliphatic acids can be racemized without by-product formation by heating an acidified solution of the organic acid at a temperature sufficient to accomplis... | 09/23/1986 |
| 4613689 | Racemization of optically active compounds having a chlorine substituted chiral carbon atom Optically active compounds having a chlorine atom attached to the chiral carbon atom such as 2-chloroaliphatic acids can be racemized without by-product formation by heating an acidified solution of the compound in the presence of chloride ion at sufficie... | 09/23/1986 |
| 4590292 | Process for the manufacture of cyclopropylamine A modified novel process for preparing cyclopropylamine from γ-butyrolactone is described. The γ-butyrolactone ring is cleaved with a hydrohalide in the presence of a novel catalyst comprising an aqueous sulfuric acid solution. The 4-chlorobutyric acid,... | 05/20/1986 |