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| Number | Title | Issue Date |
| 7358384 | Processes for the recovery of optically active diacyltartaric acids When a salt of an amine and an optically active diacyltartaric acid, or a diastereomer salt of an optically active amine and an optically active diacyltartaric acid, obtained by optically resolving a racemic amine using the optically active diacyltartaric acid, is s... | 04/15/2008 |
| 7311837 | Process for the continuous recovery of free tartaric acid from raw materials containing potassium hydrogentartrate In a process for the continuous recovery of free tartaric acid from raw materials containing potassium hydrogentartrate, the same are mixed with water and the potassium hydrogentartrate is dissolved. The process is improved in that the suspension is decanted, the cl... | 12/25/2007 |
| 7052875 | Stable gene preparations The invention is directed to the retention of the stability of formulations useful for a gene therapy during the preparation and preservation. In the invention, at least one saccharide and/or at least one non-hydrophobic amino acid and/or at least one organic acid h... | 05/30/2006 |
| 6995286 | Process for preparing isomers of salbutamol A process for making optically pure (R) and (S) salbutamol comprises obtaining the (R) or (S) isomer of either salbutamol or a salbutamol precursor in substantially optically pure form by resolving a racemic or optically impure mixture of enantiomers of salbutamol o... | 02/07/2006 |
| 6849760 | Method of preparing retroviral protease inhibitor intermediates Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective method of obtai... | 02/01/2005 |
| 6670505 | Process for the recovery of organic acids from aqueous solutions A process for recovering a desired organic acid from a solution includes the steps of: providing an aqueous solution including at least one desired organic acid or its acid anion; adjusting the proton concentration in the aqueous solution to a desired lev... | 12/30/2003 |
| 6652820 | Methods of making cesium salts and other alkali metal salts A method of making a cesium salt is described and involves reacting a cesium sulfate containing solution with lime to form 1) a solution containing at least cesium hydroxide and 2) a residue comprising calcium sulfate. The method further involves removing... | 11/25/2003 |
| 6534678 | Process for producing tartaric acid from a raw material containing potassium hydrogentartrate Process for producing tartaric acid from a raw material whose dry matter comprises at least 5 wt% potassium hydrogentartrate wherein the raw material containing potassium hydrogen tartrate (KHT) is mixed with aqueous potassium hydroxide solution in a firs... | 03/18/2003 |
| 6495711 | Process for preparing (-)-(1S, 4R) N-protected 4-amino-2-cyclopentene-1-carboxylate esters The invention relates to a process for preparing (-)-(1S,4R) N protected 4-amino-2-cylcopentene-1-carboxylate esters represented by the formula (I) ##STR1## wherein R1 and R2 are as described within the specification.... | 12/17/2002 |
| 6376223 | Process for purifying polycarboxylic acids Polycarboxylic acids are purified by contacting a crude polycarboxylic acid with a solvent to produce a substantially pure polycarboxylic acid. The solvent is chosen so that the impurities are soluble in the solvent and the polycarboxylic acid is insolubl... | 04/23/2002 |
| 6346649 | Process for the recovery and recycle of D-tartaric acid There is provided a process for the recovery of essentially enantiomerically pure D-tartaric acid from aqueous and organic waste streams generated in the resolution of racemic 2-amino-2,3-dimethylbutyronitrile via the formation and isolation of a cry... | 02/12/2002 |
| 6320069 | Production of optically active ketone Process for producing an optically active ester by reaction of a racemic alcohol with an optically active amino or tartaric acid derivative, a process for producing an optically active alcohol by hydrolysis of the optically active ester, a process for con... | 11/20/2001 |
| 6040344 | Formoterol process A method is disclosed for the preparation of optically pure isomers of formoterol by the reaction of an optically pure 4-benzyloxy-3-formamidostyrene oxide with an optically pure 4-methoxy--methyl-N-(phenylmethyl)benzeneethanamine followed by ... | 03/21/2000 |
| 5831117 | Method of preparing retroviral protease inhibitor intermediates Chiral hydroxyethylamine, hydroxyethylurea or hydroxyethylsulfonamide isostere containing retroviral protease and renin inhibitors can be prepared by multi-step syntheses that utilize key chiral amine intermediates. This invention is a cost effective meth... | 11/03/1998 |
| 5762951 | Effervescent composition and tablet made there from The present invention relates to an acidic effervescent component for direct tableting of effervescent tablets and a process for its preparation.... | 06/09/1998 |
| 5763656 | Method of preparing tartaric acid A method of preparing tartaric acid in which 5-ketogluconate is oxidized in a carbonate buffer at an alkaline pH preferably in the range of 8 to 10 using vanadate.... | 06/09/1998 |
| 5576459 | Quaternary nitrogen or phosphorus chirates An optically-active or chiral compound is described which comprises (A) at least one quaternary nitrogen or phosphorus cation provided that if the cation is a quaternary nitrogen cation containing a hydroxyalkyl group, the hydroxyalkyl group is free of chlorin... | 11/19/1996 |
| 5451687 | Process for producing O,O'-diacyltartaric anhydride and process for producing O,O'-diacyltartaric acid An industrial process for producing O,O'-diacyltartaric anhydride with high purity and high efficiency is disclosed. According to the process of the invention, a carboxylic acid of the formula (I): R1 COOH ... | 09/19/1995 |
| 5412126 | Carboxylic acid sorption regeneration process Carboxylic acids are sorbed from aqueous feedstocks into an organic liquid phase or onto a solid adsorbent. The acids are freed from the sorbent phase by treating it with aqueous alkylamine thus forming an alkylammonium carboxylate which is dewatered and ... | 05/02/1995 |
| 5349084 | Process for recovering high-purity organic acid The present invention relates to a process for inexpensively and effectively recovering a high-purity organic acid, according to which a crude organic acid is subjected to extraction treatment with an organic solvent to obtain an organic solvent extract c... | 09/20/1994 |
| 5278256 | Rapidly degradable poly (hydroxyacid) compositions The depolymerization of poly(hydroxyacids) in a liquid medium is enhanced by the presence of a quaternary ammonium compound. Poly(hydroxyacid) polymers containing a quaternary ammonium salt are more readily depolymerized.... | 01/11/1994 |
| 5245078 | Process for separating an organic acid or acids from an organic acid-containing solution A process for separating an organic acid or acids from an organic acid-containing solution obtained by a fermentation method in which glucose is used as starting material, which comprises contacting said organic acid-containing solution to a cation exchan... | 09/14/1993 |
| 5135947 | 1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors The present invention provides 1-phenyl-3-naphthalenyloxypropanamines which are selective inhibitors of serotonin uptake.... | 08/04/1992 |
| 5087746 | Process for the production of high purity tartaric acid Disodium tartrate which can be easily converted to tartaric acid is produced by hydrolysis of an epoxysuccinate. Formation of impurities is minimized and the reaction time shortened by performing the hydrolysis under superatmospheric pressure and elevated... | 02/11/1992 |
| 5017723 | Substituted ethylamines, their preparation process, their use as medicine and their synthesising agents Substituted ethylamines of the formula ##STR1## wherein R1 is phenyl optionally mono-, di- or trisubstituted by halogen, lower alkyl, lower haloalkyl or lower alkoxy, or is an aromatic heterocycle having 5 to 7 chains wherein the heteroato... | 05/21/1991 |
| 5001245 | Process for producing metallic salt of ethercarboxylic acid A preparation of metallic salt of ethercarboxylic acid in a pure form by restraining the formation of fumaric acid likely to occur when maleic acid and/or maleic anhydride react with oxycarboxylic acid. The ethercarboxylic product is a useful chelating ag... | 03/19/1991 |
| 4950783 | Treatment of hypertension Compositions containing (-)-5-{(R)-1-Hydroxy-2[(R)-1-methyl-3-phenylpropyl)amino]ethyl}salicylamid e exhibit potent vasodilating ଲ-adrenergic blocking properties and are useful for the treatment of hypertension.... | 08/21/1990 |
| 4923983 | Method of resolving cis 3-amino-4-[2-(2-furyl)eth-1-yl]-1-methoxycarbonylmethyl-azetidin-2-one Cis /ଲଲ-3-amino-[2-(2-furyl)eth-1-yl]-1-methoxycarbony lmethyl-azetidin-2-one is resolved via optically active tartaric acid.... | 05/08/1990 |
| 4820820 | Cationic surface-active compounds Cationic surface-active products of the formula: in which R1 =C4 -C20 aliphatic radical, R2 =C4 -C20 alkyl, alkoxymethyl or alkenyloxy radical, p=1-2.5, n=2-20 and G denotes an amine or amine ox... | 04/11/1989 |
| 4732709 | Preparation of optically-active di-(3-chloro-2-oxy-propyltrimethylammonium)-tartrate Process for the production of optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate. Racemic 3-chloro-2-oxy-propyltrimethylammonium-chloride is converted by racemate resolution with optically-active tartaric acid into the optically-active ... | 03/22/1988 |
| 4705894 | Process for recovery of organic acids from aqueous solutions A mixture of trialkyl phosphine oxides (HTRPO) was prepared having the formula: ##STR1## wherein R1, R2 and R3 are same or different alkyl groups of 5 to 9 carbon atoms and the total number of carbon atoms and the tot... | 11/10/1987 |
| 4704407 | Soluble dobutamine salts Hydroxyalkanoic or alkandioic acid salts of dobutamine having desirable water solubility, useful in preparing intravenous solution for treatment of cardiogenic shock.... | 11/03/1987 |
| 4692543 | Optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate Process for the production of optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate. Racemic 3-chloro-2-oxy-propyltrimethylammonium-chloride is converted by racemate resolution with CaCl2, for example, into the optically-active ... | 09/08/1987 |
| 4670192 | Optically-active di-[3-chloro-2-oxy-propyltrimethylammonium]-tartrate Process for the production of optically-active di-[3-chloro-2-hydroxy-propyltrimethylammonium]-tartrate. Racemic 3-chloro-2-hydroxy-propyltrimethylammonium-chloride is converted by racemate resolution with optically-active tartaric acid into the opti... | 06/02/1987 |
| 4656303 | Novel resolution method of racemic mixture A novel resolution method of a racemic mixture, wherein four kinds of salts are dissolved in a resolving solvent to fractionally crystallize a desired optically active isomer through an exchange reaction between counter ions.... | 04/07/1987 |
| 4652584 | Acetylenic phenoxypropanol derivatives and pharmaceutical compositions for the treatment of hypertension Phenoxypropanol derivatives having a 2-acetylenic moiety on the phenyl group thereof of the following formula (I): ##STR1## and their use as anti-hypertensives, e.g. in man. Also part of the invention are pharmaceutical compositions and intermediates... | 03/24/1987 |
| 4597902 | N-(arylthioalkyl)-N'-(aminoalkyl)ureas N-(arylthioalkyl)-N'-(aminoalkyl)ureas and thioureas and oxidation derivatives having the formula ##STR1## wherein B is thio, sulfinyl or sulfonyl; R1 and R2 are hydrogen, loweralkyl, cycloalkyl, 2-furanyl, phenyl, substituted p... | 07/01/1986 |
| 4411913 | 8'-[(3-Amino-2-hydroxy-propoxy)]-spiro-[cyclopentane-1,2'(1 'H)-(3'H)naphtalen]-4'(3'H)-ones Compounds of formula I ##STR1## wherein (i) m is O, n is 2 and p is 1 or (ii) m is 0 or 1, n is 1, and p is 1 or (iii) m is 1, n is 1 or 2 and p is 0, R1 is (i) alkyl of 3 to 7 carbon atoms or (ii) phenylalkyl, phenoxyalkyl or phenylthioalkyl o... | 10/25/1983 |
| 4399077 | Certain polyoxy perfluorinated surface active oligomers Perfluorinated surface-active block or random oligomers of the formula ##STR1## where R denotes a C2 -C18 -hydrocarbon or- hydrofluorocarbon radical, Y denotes a C6 -C13 -fluorocarbon or- hydrofluorocarbon radic... | 08/16/1983 |
| 4322437 | Spiro substituted indanones and tetralones The present invention relates to a compound of formula I, ##STR1## wherein A is straight chain alkylene of 2 to 4 carbon atoms, or straight chain alkenylene of 2 to 4 carbon atoms, n is 1, 2 or 3, R is hydrogen or halogen of atomic number from 9 to 35, an... | 03/30/1982 |