Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7435845 | Corrosion and gas hydrate inhibitors having improved water solubility and increased biodegradability Corrosion and gas hydrate inhibitors having improved water solubility and increased biodegradability The invention thus provides the use of compounds of the formula (1) where R... | 10/14/2008 |
| 7348451 | Additives for inhibiting gas hydrate formation The invention provides the use of compounds of the formula (1) where R1, R2 are each independently C1- to C22-alkyl, C2- to C22-alkenyl, C6... | 03/25/2008 |
| 7294742 | Ring-opened azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 11/13/2007 |
| 7282475 | Compositions and methods employing zwitterionic detergent combinations The present invention provides lysis reagents, containers, methods and kits relating to the extraction or the extraction and isolation of a cellular component from a host cell. More specifically, the invention provides combinations of zwitterionic compounds that may... | 10/16/2007 |
| 7214814 | Additives for inhibiting gas hydrate formation The invention provides the use of compounds of the formula (1) where R1, R2 are each independently C1- to C22-alkyl, C2- to C22-alken... | 05/08/2007 |
| 7002232 | Semiconductor integrated circuit device and method of testing the same A semiconductor integrated circuit device includes a semiconductor substrate of a first conductive type, a first well of a second conductive type provided in the semiconductor substrate, a second well of the first conductive type provided in the first well, a third ... | 02/21/2006 |
| 6992217 | Ring-opened azlactone initiators for atom transfer radical polymerization Initiators for atom transfer radical polymerizations are described. The initiators have an azlactone or ring-opened azlactone moiety to provide telechelic (co)polymers. ... | 01/31/2006 |
| 6974879 | Process for preparing single enantiomers of 5,5,5,5′,5′,5′-hexafluoroleucine and protected analogs A process for synthesizing L and D-5,5,5,5′,5′,5′-hexafluoroleucine and protected analogs is disclosed. These compounds have utility in the preparation of fluorous peptides and proteins, which display interesting and unusual properties including strong self-as... | 12/13/2005 |
| 6846952 | Process for manufacture of a 4-bromo-2-oxyimino butyric acid and its derivatives A process for producing 4-bromo-2-oxyimino butyric acid, predominantly as the (Z)-isomer of formula (I), wherein R is hydrogen; a linear or branched C1-4 alkyl group; a linear or branched C1-4 alk... | 01/25/2005 |
| 6838567 | Process for producing optically active azetidine-2-carboxylic acids An optically active N-protected azetidine-2-carboxylic acid (5) can be produced by preparing an optically active 4-amino-2-halobutyric acid (3) by halogenating an optically active 3-hydroxy-2-pyrrolidinone (1) with inversion of con... | 01/04/2005 |
| 6743940 | 4-aminobut-2-ynecarboxylic acid derivatives There are described 4-aminobut-2-ynecarboxylic acid derivatives of formula wherein R1 and R2 are each independently of the other hydrogen, C1-C20alkyl; C3-C | 06/01/2004 |
| 6706923 | Perfluoroalkyl-substituted amines, acids, amino acids and thioether acids Perfluoroalkyl-substituted amines, acids, amino acids and thioether acid compounds containing a perfluoroalkyl-iodoalkyl or perfluoroalkyl-alkene group as well as derivatives thereof, are described. They are useful as surfactants in a variety of applications where l... | 03/16/2004 |
| 6638349 | Surface treatments for pigments providing improved dispersibility and exhibiting biocidal activity A composition consisting of the reaction product of a halogenated carboxylic acid, an amine, and optionally a fatty acid. The composition has biocidal properties and enhances pigment dispersibility.... | 10/28/2003 |
| 6515179 | Process for the removal of nitrobenzenesulfonyl A 2- or 4-nitrobenzenesulfonamide is allowed to react with an alkali metal alkoxide to remove a nitrobenzenesulfonyl group to thereby obtain an amine corresponding to the amide. Furthermore, a method for producing an amine derivative by allowing the resul... | 02/04/2003 |
| 6372941 | Processes for producing ଲ-halogeno--amino-carboxylic acids and phenylcysteine derivatives and intermediates thereof An industrially advantageous method of producing ଲ-halogeno--aminocarboxylic acids is provided. Methods are also provided of producing optically active N-protected-S-phenylcysteines having high optical purity and of intermediates thereof, res... | 04/16/2002 |
| 6348092 | Surface treatments for pigments providing improved dispersibility and exhibiting biocidal activity A composition consisting of the reaction product of a halogenated carboxylic acid, an amine, and optionally a fatty acid. The composition has biocidal properties and enhances pigment dispersibility.... | 02/19/2002 |
| 6307103 | Process for the preparation of 1,1,1-trifluoro-2-aminoalkanes An improved process for the preparation of a 1,1,1-trifluoro-2-aminoalkane of formula I ##STR1## wherein R1 represents an optionally substituted alkyl group; which comprises hydrogenating the corresponding oxime of formula II ##STR2## wherein R... | 10/23/2001 |
| 6306344 | Method for retaining or enriching γ-aminobutyric acid in green grass leaves The present invention provides a method for retaining or enriching γ-aminobutyric acid in green grass leaves, which comprises the step of subjecting green grass leaves or processed products thereof to at least one treatment selected from the group consis... | 10/23/2001 |
| 6180826 | Oil and alcohol repellent fluorinated surfactants and intermediates, derivatives and uses thereof New water-soluble polyperfluoroalkyl surfactants derived from functional polycarboxylic polymers, characterized by the fact they have alco-oleophobic properties, to be used in the make-up of protein or synthetic foam for extinguishing fires caused not onl... | 01/30/2001 |
| 6166259 | Process for preparing a 1,1,1-trifluoro-2-aminoalkane The invention relates to a process for the preparation of a 1,1,1-trifluoro-2-aminoalkane of formula I ##STR1## wherein R1 represents an optionally substituted alkyl group; which comprises heating a mixture consisting essentially of a comp... | 12/26/2000 |
| 6156222 | Poly-perfluoroalkyl substituted polyamines as grease proofing agents for paper and foam stabilizers in aqueous fire-fighting foams Perfluoroalkyl-allyloxy- and perfluoroalkyl-iodopropyloxy-substituted polyaminoacids or poly-RF -fluoroallyl-substituted polyaminoacids which contain, in random distribution, q units of A-1, r units of A-2, s units of A-3 and t units of A-4 in ... | 12/05/2000 |
| 6069272 | Simplified method for the production of vinyl glycine (2-aminobut-3-enoic acid) and a convenient resolution of a derivative The invention relates to a three-step synthesis of vinyl glycine (1) using a cheap, commercially available starting material (3-butenenitrile (2)) and using cheap, simple reagents. Also disclosed is a convenient optical resolution of the N-tert.butyloxyca... | 05/30/2000 |
| 6018050 | Method of preparing optically active -amino acids and -amino acid derivatives The invention relates to a new process for the preparation of optically active amino acids and amino acid derivatives of the general formula (I), wherein *, X and R1 to R4 have the meaning given in the description. Starting from comm... | 01/25/2000 |
| 5905127 | Polymerizable mesophases based on substituted unsaturated carboxylic acids Mesogens are provided based on substituted unsaturated carboxylic acids such as acrylic and methacrylic acid. Substitution of a variety of hydrophobic tails onto the carboxylic acid or acid derivative via the vinyl carbon proximal to the carbonyl of the c... | 05/18/1999 |
| 5872287 | Amphipathic compound having succinic acid skeleton Provided are an amphipathic compound represented by any of the following Formulas: ##STR1## (R1 is a linear or branched, saturated hydrocarbon group having 6 to 48 carbon atoms, or a linear or branched, unsaturated hydrocarbon group c... | 02/16/1999 |
| 5856538 | Preparation of N-acylamino carboxylic acids and N-acylamino sulfonic acids and their alkali metal salts N-acylamino carboxylic acids and N-acylamino sulfonic acids and their alkali metal salts from the technical alkali metal salts of amino carboxylic acids and amino sulfonic acids, respectively, with an active content of 50-95% by weight, based on the solid... | 01/05/1999 |
| 5808146 | Amino acid analogs for tumor imaging The invention provides novel amino acid compounds of use in detecting and evaluating brain and body tumors. These compounds combine the advantageous properties of 1-amino-cycloalkyl-1-carboxylic acids, namely, their rapid uptake and prolonged retention in... | 09/15/1998 |
| 5700840 | Fluoroalkenyl compounds and their use as pest control agents Fluorinated alkene compounds useful for controlling nematodes, insects, and acarids that prey on agricultural crops, these compounds having the formula BrCF2 CFClCH2 CO--R where R is R1 or R2. R1 is -... | 12/23/1997 |
| 5672583 | Carboxy-peptidyl derivatives as antidegenerative active agents Novel Carboxy-peptidyl compounds of Formula I are found to be useful inhibitors of matrix metalloendoproteinase-mediated diseases including osteoarthritis, rheumatoid arthritis, septic arthritis, tumor invasion in certain cancers, periodontal disease, cor... | 09/30/1997 |
| 5654477 | Processes for preparing (S)-4-amino-hepta-5,6-dienoic acid and intemediates thereof The present invention relates to a novel enantiospecific processes for preparing (S)-4-amino-hepta-5,6-dienoic acid and pharmaceutically acceptable salts thereof, which is useful as an irreversible inhibitor of GABA-T, to novel intermediates thereof, and ... | 08/05/1997 |
| 5648528 | Saturated fluoroalkylamines and their derivatives, and mixtures thereof New saturated fluoroalkylamines and carboxyalkylbetaines and alkylsulfobetaines derived therefrom, and mixtures containing the new fluoroalkylamines and mixtures containing the new fluorobetaines are described. The saturated fluoroalkylamines conform to t... | 07/15/1997 |
| 5455234 | Inhibition of hair growth Mammalian hair growth is reduced by applying to the skin an inhibitor of a cysteine synthetic pathway enzyme.... | 10/03/1995 |
| 5442088 | Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process Process for the preparation of phosphorus-containing L-amino acids, their derivatives and intermediates for this process L-amino acids of the formula I and salts thereof, ##STR1## in which R1 to R5 are defined as in claim 1 and n is ... | 08/15/1995 |
| 5436372 | Solid state displacement elements The invention is intended to provide novel solid state displacement elements that have an extent of displacement. The solid state displacement element has an intercalation compound in which a polar compound (B) is mixed with an inorganic layered compound ... | 07/25/1995 |
| 5399590 | Quaternary ammonium salts and pharmaceutical compositions containing them The invention relates to the field of organic chemistry and more particularly to that of therapeutic chemistry. More particularly it relates to new quaternary ammonium salts of general formula (I): ##STR1## in which Hal is a halogen atom other than f... | 03/21/1995 |
| 5380936 | Process for preparing 4-amino-5-hexenoic acid This invention relates to a novel synthesis of 4-amino-5-hexenoic acid by thermal rearrangements, and to the novel intermediates produced thereby.... | 01/10/1995 |
| 5324504 | Perfluoro-t-butyl-containing compounds for use in fluorine-19 NMR and/or MRI Accordingly, the present invention is directed to biological compounds derivatized so as to contain at least one perfluoro-t-butyl moiety for use in fluorine-19 NMR and/or MRI studies. The perfluoro-t-butyl (PFTB) moiety, ##STR1## is an excellen... | 06/28/1994 |
| 5256394 | Radiological imaging method, and contrast media reagents therefor A method of imaging a corporeal situs by radiological techniques, comprising delivery to the corporeal situs of an imagingly effectively amount of a physiologically acceptable composition comprising a boron reagent. A variety of illustrative boron reagent... | 10/26/1993 |
| 5153358 | Process for the preparation of alpha-alkylated alpha-amino acids and alpha-halogenated alpha-amino acids A novel process for the preparation of -alkylated -amino acids and -halogenated -amino acids is disclosed. These -alkylated -amino acids and -halogenated -amino acids are useful as intermediates for ... | 10/06/1992 |
| 5096700 | Halogenated aminohexanoates and aminobutyrates antimicrobial agents The subject invention involves halogenated amino acid derivatives useful as antimicrobial agents having the structure: ##STR1## wherein --R is hydrogen or 2-aminoethyl; --R' is hydroxy, alkoxy, aryloxy, or an amino acid residue bonded at the amino ni... | 03/17/1992 |
