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Class 562/573 - Glutamic acid per se or salt thereof


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: The compound which is glutamic acid or its salts and processes
No. of patents: 52
Last issue date: 04/17/2007


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NumberTitleIssue Date
7205273Fusogenic liposomes
The present invention relates to liposomes and virosomes and, more particularly, to liposomal and virosomal delivery systems for transporting materials such as drugs, nucleic acids and proteins. ...
04/17/2007
7157449Medicament for the treatment of diseases caused by parasitic protozoa
The present invention relates to the use of an inhibitor of CTP synthetase, such as a glutamine analogue, and a substance capable of suppressing toxic effects thereof in vivo, in the manufacture of a medicament for the treatment of a disease caused by a parasitic pr...
01/02/2007
7129375Metal complexes of α amino dicarboxylic acids
Neutral alpha amino diacid complexes of trace minerals and their use for animal nutrition. ...
10/31/2006
7101855Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4
Disclosed are pyroglutamic acid derivatives and related compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseas...
09/05/2006
6992067Diphenylazetidinones, process for their preparation, medicaments comprising these compounds and their use
Compounds of the formula I, in which R1, R2, R3, R4, R5, and R6 have the meanings given in the description, and their physiologically acceptable salts. The compounds are suitable for use, for example, as hypolipidemics....
01/31/2006
6977311Process for synthesizing L-γ-methylene glutamic acid and analogs
A process for synthesizing substantially enantiomerically pure L-amino acids, particularly L-γ-methylene glutamic acid, and esters and salts thereof. The process includes the derivatization of (2S)-pyroglutamic acid, and the decyclization of the resulting derivativ...
12/20/2005
6942803Process for purifying an organic acid
A process is disclosed for purifying an aqueous feed stream comprising a product organic acid, such as lactic acid, and a strong contaminant, such as pyruvic acid or oxalic acid. The molar concentration of the product organic acid in the feed stream typically is at ...
09/13/2005
6911431Pharmaceutical angiostatic dipeptide compositions and methods of use thereof
Disclosed are methods of inhibiting neovascularization in a subject by administering to the subject a pharmaceutical preparation of R′-Glu-Trp-R″. ...
06/28/2005
6881861Method of purifying glutamic acid by transition recrystallization
Disclosed herein is a method of purifying L-glutamic acid by transformation recrystallization which method comprises maintaining crude crystals of L-glutamic acid containing α crystals of L-glutamic acid in an aqueous solvent at a temperature of from 50° C. to the...
04/19/2005
6777396Feed for livestock
A composition for livestock feed, comprising a feed for livestock and at least two additives selected from the group consisting of nucleic acid, glutamine and glutamic acid; and a method for increasing body weight gain efficiency and feed efficiency in livestock, co...
08/17/2004
6696611Chemical methods
The present invention provides a method for enantioselectively reducing a prochiral carbon centered radical having one or more electron donator groups attached directly to the central prochiral carbon atom of the radical, and/or attached to a carbon atom ...
02/24/2004
6673942Resolution of DL-racemic mixtures
The present invention relates to a process for the resolution of DL-racemic mixtures of compounds which crystalize in the form of a conglumerate. Both, the D and L-enantiomers are obtained according to the invention in a industrially feasable process by a...
01/06/2004
6627732Glutathione derivatives and their dosage forms
The present invention provides a glutathione derivative having a dramatically enhanced hematopoiesis promoting effect in the living body represented by the formula (I): ##STR1## where A represents H or a C1-C20 acyl group; R1 represents a C...
09/30/2003
6600069Benzene tricarboxylic acid derivatives as insulin receptor activators
Compounds of Formula I, and pharmaceutical compositions containing these compounds, activate the insulin receptor kinase, which leads to an increased sensitivity to insulin and an increase in glucose uptake, and are therefore useful for the treatment of a...
07/29/2003
6599940Synthesis of 2-hydroxymethylglutamic acid and congeners thereof
One aspect of the present invention relates to 2-hydroxymethylglutamic acid and congeners thereof. A second aspect of the invention relates to a method of synthesizing 2-hydroxymethylglutamic acid and congeners thereof....
07/29/2003
6414029Vanadium complexes of monohydroxamates and pharmaceutical compositions comprising them
Monohydroxamate vanadium complexes of the formula (1): R--CO--NHOH.X, wherein R is a residue selected from: (i) H2 N--CH(COY)--(CH2)n --, wherein n is 1, 2 or 3, and Y is OH or NH2 ; (ii) H2 N--CH
07/02/2002
6392094Method for recovering amino acids
A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer comprising an Na type or K type strongly acidic ion exchange ...
05/21/2002
6306840Cell adhesion inhibitors
The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of us...
10/23/2001
6201132Inhibitors of DP-mediated processes, compositions, and therapeutic methods thereof
Compounds selected from those of general formula ##STR1## and A is selected from specified aminoacyl compounds are inhibitors of DP-IV mediated processes....
03/13/2001
6147259Process for producing glutamic acid
An indirect acidulation process for producing glutamic acid from an aqueous feed containing a glutamate resulting from fermentation includes: a) contacting an aqueous feed stream at an elevated temperature with a weak acid cation exchanger (WACE) which is...
11/14/2000
6051734Process for the optical resolution of 3-(p-chlorophenyl)-glutaramide
A process for the optical resolution of racemic 3-(p-chlorophenyl)glutaramide (GAM) into its R isomer R--COOH and its S isomer S--COOH, which process includes the steps of either: (1) reacting racemic 3-(p-chlorophenyl)-glutaramide dissolved in a suitable ...
04/18/2000
5998594Self-assembling, chromogenic receptors for the recognition of medically important substrates and their method of use
A chromogenic receptor comprises a self-assembled chromogenic compound having at least one intrinsic binding site. The chromogenic compound is characterized by the property of producing a reversible color change responsive to binding a target substrate to...
12/07/1999
5994560Resolution of racemic mixtures using polymers containing chiral units
Described herein is a novel process to resolve a racemic compound into its optically active isomers without need for chemical transformation such as salt formation. The process advantageously utilizes polymers containing chiral moieties in their repeat un...
11/30/1999
5990165Pharmaceutical compounds
A pharmaceutical compound of the formula: ##STR1## in which n is 1 or 2, R1 is --CO2 H, R2 is hydrogen or C1-4 alkyl and R3 is hydrogen, C1-10 alkyl, C2-10 alkenyl, optionally ...
11/23/1999
5981564Water-soluble derivatives of paclitaxel, method for producing same and uses thereof
The invention relates to new paclitaxel derivatives showing an increased solubility in water. More particularly, the invention relates to glutarylpaclitaxel, glutarylpaclitaxel 6-aminohexanol glucuronide and to different amino acid derivatives of the glut...
11/09/1999
5907059Process for the preparation of monosodium glutamate
The invention provides a process for the preparation of monosodium glutamate from a fermentatively prepared solution containing monoammonium glutamate, the process comprising: a) contacting the solution containing monoammonium glutamate salt with a basic ...
05/25/1999
5837872Process for preparation of N-acyl-aminodiacids
This invention relates to an improved process for preparing selected N-acyl-aminodiacids such as lauroyl glutamic acid....
11/17/1998
5770625Butyryl-tyrosinyl spermine, analogs thereof and methods of preparing and using same
The present invention provides a compound having the structure: ##STR1## wherein R1 is hydrogen or a branched or unbranched, substituted or unsubstituted aminoalkyl having from two to twenty atoms in the chain, R2 is hydrogen, m...
06/23/1998
5559092Cosmetic composition
A composition suitable for topical application to mammalian skin and hair for inducing, maintaining or increasing hair growth comprises a hair growth promoter chosen from glutamine derivatives and salts thereof. The composition preferably also comprises a...
09/24/1996
5536815Cyclopropyl based O- and N- and S-protecting groups
The present invention is directed to the use of a cyclopropylmethyl derivative as a protecting group for compounds containing an amino group, carboxy group, amido group, mercapto group or hydroxy group and to the compounds formed having the cyclopropylmet...
07/16/1996
5492895Inhibitors of thrombosis
This invention relates to peptide aldehyde analogs that inhibit the thrombin or Factor Xa. The compounds are thought useful for preventing or treating conditions in mammal characterized by abnormal thrombosis....
02/20/1996
5428063Use of betaine as a hepatic generator of S-adenosylmethionine and as a protective agent against hepatotoxicity
This invention encompasses pharmaceutical compositions in the dietary supplement for treating or preventing fatty infiltration, the first stage of cirrhosis of the liver comprising and administering of not less than 1500 mg of betaine per kg of body weigh...
06/27/1995
5279744Method for purification of an amino acid using ion exchange resin
A method for purification of an amino acid which comprises contacting an amino acid solution containing impurities with an ion exchange resin to selectively adsorb the amino acid onto the resin, eluting and recovering the adsorbed amino acid whereby the r...
01/18/1994
5187270Racemization free attachment of amino acids to a solid phase
This invention pertains to amino acids attached to a solid support in a racemization free manner and to a method of covalently linking amino acids to solid supports for use in solid phase peptide syntheses....
02/16/1993
5091559Process for the preparation of alkyl 4-oxobutyrate and its acetals
A process is disclosed for forming alkyl 4-oxobutyrates and its acetals which comprises reacting under anhydrous conditions acrolein or its acetals with carbon monoxide and an alcohol of the formula R OH wherein R is lower alkyl in the presence of a catal...
02/25/1992
5066828Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
This invention relates to certain conjugates of folates and antifolates with difluoroglutamic acid which are useful in the treatment of patients suffering from certain neoplastic diseases including leukemia, melanomas, carcinomas, sarcomas and mixed neopl...
11/19/1991
4942248Tertiary-alkyl esters of 1H-benzotriazole-1-carboxylic acids
Tertiary-butyl and tertiary-amyl esters of 1H-benzotriazole-1-carboxylic acids are useful blocking agents for blocking the amino or imino groups of amino acids. The six-membered ring of the blocking agent may be unsubstituted or substituted with one or mo...
07/17/1990
4929755Process for making an optically active mixture of an N-acyl-amino acid or ester containing at least two chiral centers
In the process of hydrocarboxylating an ଱-enamide with CO and H2 O or an organic hydroxyl compound to produce an N-acyl-଱-amino acid or ester, respectively, the improvement comprising using as the ଱-enamide reactant, an ³...
05/29/1990
4912228Process of extraction of amino acids from aqueous solutions thereof
An improvement in the process of extraction of amino acids from aqueous solutions in which the amino acids are extracted with quaternary ammonium extractants. A pretreatment of the amino acid containing aqueous solution with a tertiary amine prior to extr...
03/27/1990
4721803Method of making a diastereomeric mixture containing two diastereomeric N-acyl-amino acid esters
In the process of hydrocarboxylating an ଱-enamide with CO and an organic hydroxyl compound to produce a N-acyl-଱-amino acid ester, the improvement comprising using as the organic hydroxyl compound reactant, an organic hydroxyl compound which h...
01/26/1988
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