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| Number | Title | Issue Date |
| 7411031 | Synthesis of polyanhydrides The present invention provides a method for forming compounds of Formula HO—C(═O)R1—X—R2—X—R1—C(═O)—O—H wherein compound (I) can be polymerized to provide a polymer that contains therapeuticall... | 08/12/2008 |
| 7247722 | Polysaccharide aldehydes prepared by oxidation method and used as strength additives in papermaking Polysaccharide aldehydes are prepared using selective oxidation involving the use of nitroxyl radical mediated aqueous oxidation with a limited amount of oxidant and defined reaction conditions. These polysaccharide aldehyde derivatives having maximum effective alde... | 07/24/2007 |
| 7211682 | Aqueous solution of a sodium salt of HEDTA The invention pertains to an aqueous solution of a sodium salt xNa+ yH+ of the chelating compound of formula I: wherein x=2.1–2.7, y=0.9–0.3, and x+y=3. The invention further pertains to... | 05/01/2007 |
| 7157092 | Acyl pseudodipeptides, preparation method and pharmaceutical compositions containing same Compounds of the formula wherein the substitutents are defined as in the specification useful for modulating immune responses in warm-blooded animals. ... | 01/02/2007 |
| 7141689 | Metal complexes of alpha amino dicarboxylic acids Neutral alpha amino diacid complexes of trace minerals and their use for animal nutrition. ... | 11/28/2006 |
| 7014699 | Oxalkylation products produced from epoxides and amines and their use in pigment preparations The invention relates to addition compounds of formula (1): in which: n is a number from 1 to 10; R1 and R2 are identical or different and are each a hydrogen atom or a saturated or unsaturated ali... | 03/21/2006 |
| 6900351 | Aminopolycarboxylates, process for producing the same and use thereof An aminopolycarboxylate is described, which is represented by the following formula (1): wherein M1, M2, M3 and M4 independently represent each an alkali metal ion. A process... | 05/31/2005 |
| 6855711 | Pharmaceutical compositions comprising iron chelators for the treatment of neurodegenerative disorders and some novel iron chelators Use of a compound of formula (I), wherein R1 is H or hydrocarbyl; R2 is a hydrophobic radical; R3 is 3-(C2-C6)acyl-4-hydroxyphenyl, 3-hydroxyimino (C2-C6)-alkyl-4-hydroxyphenyl, or COOZ, wh... | 02/15/2005 |
| 6852755 | Nitrogen mustard compounds and prodrugs therefor This invention pertains to nitrogen mustard compounds (Formula (II)) and prodrugs therefor (Formula (I)), methods for their preparation, pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo,... | 02/08/2005 |
| 6759549 | Method of preparing amino carboxylic acids Novel compounds, N,N′-bis(phosphonomethyl)-N,N′-bis(hydroxycarbonylmethyl)urea and N,N,N′,N′-tetrakis(hydroxycarbonylmethyl)urea, suitable for use in preparing N-acyl aminocarboxylic acids that can be readily converted to N-(phosphonomethyl)glycine are provi... | 07/06/2004 |
| 6740756 | Fluorescent lanthanide chelates The present invention provides complexing agents of Formula I which contain novel photosensitizers and produce long-lived fluorescence for use in bioaffinity assays, especially HTRF (homogeneous time-resolved fluorescenc... | 05/25/2004 |
| 6677483 | Process for the production of monoamides of DTPA A new process for the preparation of diethylenetriaminepentaacetic-monoamides in which amines can be reacted with sensitive groups, a higher mono/diamide selectivity is achieved, a higher yield of monoamide is achieved and has a simple reaction scheme and... | 01/13/2004 |
| 6652834 | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents Substituted polycarboxylic ligand molecules and corresponding metal complexes of said ligands, preferably paramagnetic metals complexes for generating responses in the field of magnetic resonance imaging (MRI) The paramagnetic complexes of the polycarboxy... | 11/25/2003 |
| 6649793 | Process for the preparation of a N,N-diamino amino acid-ଲ-hydroxy disuccinic acid A process of the preparation of a N,N-diamino amino acid-ଲ-hydroxy-succinic acid as a N,N-diacid salt (I) is described. The process involves reacting epoxy succinic acid with an amino acid having two amino groups as an N-acid salt. The compounds are... | 11/18/2003 |
| 6518419 | Process for selective oxidation of primary alcohols Primary alcohols, especially in carbohydrates, can be selectively oxidized to aldehydes and carboxylic acids in a low-halogen process by using a peracid in the presence of a catalytic amount of a di-tertiary-alkyl nitroxyl (TEMPO) and a catalytic amount o... | 02/11/2003 |
| 6515175 | Mono-and polyamides of perfluoroalkyl-substituted unsaturated acids Novel perfluoroalkyl-substituted mono-, di- and poly-amide compounds which are reaction products of a mono-, di- or polyamine of 60 to 2000 molecular weight with a perfluoroalkyl substituted unsaturated acid or its corresponding lower alkyl ester and opti... | 02/04/2003 |
| 6515174 | Preformed multi-acid adducts useful for grafting polyolefin polymers The present invention relates to reaction products formed from maleic anhydride and amino carboxylic acids. The reaction products are particularly useful for grafting polyolefins to increase their polarity and therefore enhance their physical properties.... | 02/04/2003 |
| 6503739 | Processes for producing S,S-2-hydroxypropylenediamine-N-N'-disuccinic acid Provided is an industrially advantageous process for producing S,S-2-hydroxypropylenediamine-N,N'-disuccinic acid which does not use expensive optically active substances. S,S-2-hydroxypropylenediamine-N,N'-disuccinic acid is stereospecifically produ... | 01/07/2003 |
| 6492549 | Process for preparing alkylene diamine triacetic acid A process for the preparation of alkylene diamine triacetic acid (derivatives) which comprises the conversion of an alkylene diamine (derivative) to a metal salt of an alkylene diamine triacetic acid (derivative). The reaction is carried out in the presen... | 12/10/2002 |
| 6455726 | Manufacturing method A compound of the following formula (II) and a process for preparing of the compound of the following formula (I) its preparation ##STR1## wherein R1 is carboxy or protected carboxy; R2 is lower alkoxy or higher alkoxy; A1 is a... | 09/24/2002 |
| 6455715 | Method of producing dicarboxylic acids suitable for synthesis of polymers or polyamides A method is described for producing saturated dicarboxylic acids with a chain length of C6 to C21 or the corresponding diamidic dicarboxylic acids from fatty acid cleavage of unsaturated fatty acids or the bis-fatty acid diamides of these unsaturated fatt... | 09/24/2002 |
| 6437181 | Method for producing (S,S)-N,N'-ethylenediaminedisuccinic acid, analogous compounds or salts thereof The invention describes a process for the preparation of (S,S)-N,N'-ethylenediaminedisuccinic acid or analogous compounds or their salts by reaction of L-aspartic acid, L-glutamic acid or L-cysteic acid with 1,2-bissulfooxyethane, 1,3,2-dioxathiolane 2,2-... | 08/20/2002 |
| 6395930 | Quenching reagents for solution phase synthesis A method for enhancing the purity of a desired compound comprising: Step (a) treating a crude reaction product which contains at least one desired compound, unreacted starting materials and/or byproducts with at least one bifunctional quenching agent that is c... | 05/28/2002 |
| 6384279 | Synthesis of a tetraamido macrocycle ligand from a novel diamidodiol A new composition of matter for a diamidodiol and a method for preparing the diamidodiol. The exemplary diamidodiol has the formula C15 H30 N2 O4 and is prepared by reacting a first quantity of 2-amino-2-methyl-... | 05/07/2002 |
| 6340560 | Aminopolycarboxylic acid chelating agent, heavy metal chelate compound thereof, photographic additive and processing method An aminopolycarboxylic acid compound represented by the following formula or analogous thereof: ##STR1## The aminopolycarboxylic acid compound of the present invention can be used as a chelating agent for various metals, which is excellent in the bio... | 01/22/2002 |
| 6303761 | Triaminepentaacetic acid compound and paramagnetic metal complex prepared from using the compound as ligand The present invention provides a triaminepentaacetic acid compound which can be used as a ligand to coordinate to a metal ion to form a paramagnetic metal complex. The paramagnetic metal complex of the present invention can be used as a contrast agent for... | 10/16/2001 |
| 6297397 | Method for producing highly pure tetrasodium salt of ethylenediaminetetraacetic acid A method for producing highly purified crystals of tetrasodium. Salt of ethylenediaminetetraacetic acid including reacting ethylene diamine, NaCN and formalin in the presence of an alkali to yield a solution containing EDTA4Na and impurities. This solutio... | 10/02/2001 |
| 6278020 | Alkylation of amino acids This invention provides improvements in certain processes for alkylating amino acids whereby yields based on amino acid are improved. More specifically, the invention provides a process for the preparation of amino acid derivatives in free acid or salt fo... | 08/21/2001 |
| 6254850 | Metal complexes, suitable for use in diagnosis and therapy The invention relates to diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, containing an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents containing these compounds, their use as contrast media and an... | 07/03/2001 |
| 6245941 | Reductive alkylation process for the preparation of compounds containing at least two amino groups An alkylation process is described. The process comprises reacting at least a first nitrogen compound and a second nitrogen compound with a carbonyl compound in the presence of a reducing agent to form a product comprising at least two nitrogen groups; wh... | 06/12/2001 |
| 6232496 | Process for the preparation of amphoacetate surfactants Amphoacetate surfactants are made by reacting a compound of formula RCONHCH2 CH2 NHCH2 CH2 OH where R is an aliphatic radical, with formaldehyde and a cyanide of formula: R1 CN, wherein R1 represents... | 05/15/2001 |
| 6180826 | Oil and alcohol repellent fluorinated surfactants and intermediates, derivatives and uses thereof New water-soluble polyperfluoroalkyl surfactants derived from functional polycarboxylic polymers, characterized by the fact they have alco-oleophobic properties, to be used in the make-up of protein or synthetic foam for extinguishing fires caused not onl... | 01/30/2001 |
| 6153775 | Polydentate imines and their metal complexes Tripodal chelating agents incorporating imine C.dbd.N bonds are disclosed for the formation of lanthanide and other metal complexes which are relatively stable in the presence of water at neutral pH.... | 11/28/2000 |
| 6140367 | Use of ethylene diamine disuccinate for preparing a medicament with antiviral properties Use of (S,S)-N,N'-ethylenediamine disuccinate (EDDS) of formula I wherein M.dbd.H+ and/or any pharmaceutically acceptable cation, for the preparation of a medicament for the treatment of cytomegaloviral infections which has immunosuppressive p... | 10/31/2000 |
| 6075164 | Alkylation of amino acids This invention provides improvements in certain processes for alkylating amino acids whereby yields based on amino acid are improved. More specifically, the invention provides a process for the preparation of amino acid derivatives in free acid or salt fo... | 06/13/2000 |
| 6040432 | Metal complexes, of DTPA derivatives suitable for use in diagnosis and therapy The invention relates to diethylenetriaminepentaacetic acid derivatives, their complexes and complex salts, containing an element of atomic numbers 20-32, 39-51 or 57-83, pharmaceutical agents containing these compounds, their use as contrast media and an... | 03/21/2000 |
| 6034271 | Betaine gemini surfactants made from amines Amphiphilic amphoteric compounds of formula (I) ##STR1## wherein R1, R2, R3, R4, R5, and n are as defined in the disclosure.... | 03/07/2000 |
| 6031132 | Amide-group-containing polyacetal and its production process and use An amide-group-containing polyacetal, having acetal structure unit (1) of general formula (1) below in its molecule. This amide-group-containing polyacetal is usable as a detergent builder for detergent compositions. ##STR1## A production process of ... | 02/29/2000 |
| 6011152 | Synthesis of macrocyclic tetraamido-N ligands New synthetic methods for the preparation of macrocyclic amido-N donor ligands are provided. The primary method of the present invention involves in general only two synthetic steps. In the first step, an or ଲ amino carboxylic acid is allowe... | 01/04/2000 |
| 6005141 | Use of glycine-N,N-diacetic acid derivatives as biodegradable complexing agents for alkaline earth metal ions and heavy metal ions and process for the preparation thereof Glycine-N,N-diacetic acid derivatives and their alkali metal, alkaline earth metal, ammonium and substituted ammonium salts are used as complexing agents for alkaline earth metal and heavy metal ions with the exception of -alanine-N,N-diacetic acid... | 12/21/1999 |
