Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 8101795 | Process for preparing high purity corosolic acid and high purity ursolic acid According to the present invention, there is provided a process for preparing corosolic acid comprising the steps of (1) dissolving crude extract of Japanese loquat leaves in alkali and aqueous alcohol and (2) applying the solution to a nonpolar adsorption resin to ... | 01/24/2012 |
| 7795468 | Functionalized higher diamondoids This invention is directed to functionalized higher diamondoids having at least one functional group. Preferably these derivatives have the following Formula I: wherein D is a higher diamondoid nucleus and wherein R1 | 09/14/2010 |
| 7435848 | Method for preparing alicyclic carboxylic acids and their esters A method for the continuous preparation of an alicyclic carboxylic acid or an ester of the alicyclic carboxylic acid. A plastic which incorporates the alicyclic carboxylic acid or an ester of the alicyclic carboxylic acid. An article made of a plastic which incorpor... | 10/14/2008 |
| 7432390 | Production of carboxylic acids or carboxylic acid esters In the production of carboxylic acid or carboxylic acid ester, a reaction product containing the carboxylic acid or carboxylic acid ester which has been produced by the reaction of an olefin, carbon monoxide, and water or an alcohol in the presence of HF is heat-tre... | 10/07/2008 |
| 7402712 | Adamantyl vinyl ether compound and production process for the same Provided by the present invention are an adamantyl vinyl ether compound which is useful as a monomer for functional resins in the photolithography field or a raw material therefor and medical and agricultural intermediates and a production process for the same. ... | 07/22/2008 |
| 7371889 | Chemical entities with multiple modes of anti-inflammatory action The invention relates to new chemical compounds that inhibit the various enzymes in the arachidonic acid pathway implicated in inflammatory disease conditions. ... | 05/13/2008 |
| 7288671 | Interleukin-1 and tumor necrosis factor-α modulators, synthesis of said modulators and their enantiomers and methods of using said modulators Novel compounds are disclosed that have the following chemical structures, and prodrug esters and acid-addition salts thereof, that are useful as Interleukin-1 and Tumor Necrosis Factor-α modulators, and thus are useful in the treatment of various diseases. ... | 10/30/2007 |
| 7223882 | Process for producing triterpene derivative A process for a preparation of Compound (V), a pharmaceutically acceptable salt or a solvate thereof, said process comprising the steps represented by the following formula: wherein R1 and R2 | 05/29/2007 |
| 7195790 | Modification of cyclooxygenase and lipoxygenase activity with asteridae extracts and optionally boswellic acid Extracts from plants in the Asteridae subfamily, such as Carthamus tinctorious, are effective to selectively inhibit COX-2 activity and/or enhance COX-1 activity. When Asteridae extracts are combined with boswellic acid, the combination exhibits a synergistic... | 03/27/2007 |
| 7173151 | Cycloalkyl-substituted alkanoic acid derivatives, processes for their preparation and their use as pharmaceuticals The invention relates to arylcycloalkyl-substituted derivatives and to their physiologically acceptable salts and physiologically functional derivatives. What is described are compounds of the formula I, i... | 02/06/2007 |
| 7119223 | Interleukin-1 and tumor necrosis factor-α modulators, synthesis of said modulators and their enantiomers and methods of using said modulators Novel compounds are disclosed that have the following chemical structures, and prodrug esters and acid-addition salts thereof, that are useful as Interleukin-1 and Tumor Necrosis Factor-α modulators, and thus are useful in the treatment of various diseases. ... | 10/10/2006 |
| 7071229 | Process for producing corosolic acid This invention provides an improved process for producing corosolic acid starts from ursolic acid, which occurs in plants in relatively large amounts, the method comprising the steps of oxidizing the hydroxyl group at 3-position and utilizing the carbonyl group at 3... | 07/04/2006 |
| 7033728 | Photoresist composition The present invention relates to a photosensitive composition useful at wavelengths between 300 nm and 10 nm which comprises a polymer containing a substituted or unsubstituted higher adamantane. ... | 04/25/2006 |
| 6930128 | Estrogenic compounds as anti-mitotic agents The application discloses methods of treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of the general formulae found below in a dosa... | 08/16/2005 |
| 6891063 | Salts of asiatic and madecassic acid suitable for the preparation of pharmaceutical and cosmetic compositions Salts of asiatic and madecassic acid with pharmaceutically acceptable organic bases, suitable for the preparation of pharmaceutical and cosmetic compositions for the topical and systemic treatment of erithema, varicose ulcers, venous insufficiency, bedsores, delayed... | 05/10/2005 |
| 6884908 | Process for isolation of hepatoprotective agent “oleanolic acid” from Lantana camera Accordingly the present invention provides an improved and economical process for the isolation of oleanolic acid from the roots of Lantana camara, which comprises of drying, grinding and defattening of Lantana camara roots with light petroleum followe... | 04/26/2005 |
| 6881857 | Tricyclic diterpene derivatives Disclosed herein are novel tricyclic diterpene compounds. These compounds, including their prodrug esters and acid-addition salts, are useful as Interleukin-1 and Tumor Necrosis Factor-α modulators, and thus are useful in the treatment of various diseases. A... | 04/19/2005 |
| 6878723 | LTA4 hydrolase inhibitors The invention concerns compounds inhibiting LTA4 hydrolase of formula (I). The invention also concerns their therapeutic, in particular anti-inflammatory, applications. ... | 04/12/2005 |
| 6864278 | Antifungal agents of sordarin derivatives Sordarin derivatives prepared from C-11-hydroxysordarin are antifungal agents useful in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops. ... | 03/08/2005 |
| 6846941 | Process for separating unsaponifiable valuable products from raw materials Disclosed are processes for separating valuable products, including unsaponifiable materials, from any given matrix of raw materials that is mainly composed of saponifiable components and unsaponifiable components. Preferred methods include converting sodium or pota... | 01/25/2005 |
| 6794111 | Polymers, resist compositions and patterning process, novel tetrahydrofuran compounds and their preparation A polymer comprising recurring units of formula (1-1) or (1-2) wherein R1, R2, R3 and R4 are H or alkyl, or R1 and R2, and R3 and R4 taken together may form a ring with each pair... | 09/21/2004 |
| 6740778 | Method for the preparation of oleanolic acid and/or maslinic acid The present invention relates to a method for preparing oleanolic acid and/or maslinic acid and physiologically acceptable salts thereof, which comprises the steps of extracting olive plant and/or products obtained in the olive oil-manufacturing processes with water... | 05/25/2004 |
| 6700014 | Process for extracting oleanolic acid from plant material A process for extracting oleanolic acid from plant material is disclosed. Dried plant material is provided and an extraction process is carried out with a non-halogenated polar to medium polar solvent. The resulting solution that contains oleanolic acid i... | 03/02/2004 |
| 6603041 | Bicyclic enamide derivatives Enamide derivatives of formula (1) are described: ##STR1## wherein R1 is a group Ar1 L2 Ar2 Alk- in which Ar1 is an optionally substituted aromatic or heteroaromatic group, L2 is a covalent... | 08/05/2003 |
| 6586619 | Photoresist monomer having hydroxy group and carboxy group, copolymer thereof and photoresist composition using the same The present invention relates to novel monomers which can be used to form polymers which are useful in a photolithography employing a light source in the far ultraviolet region of the light spectrum, copolymers thereof, and photoresist compositions prepar... | 07/01/2003 |
| 6576786 | Process for preparing substituted cyclopentane derivatives and novel crystalline structures thereof The invention relates to a process for preparing substituted cyclopentane derivatives represented by the formula (I) ##STR1## wherein R1, R2, R3, R4, X and Y are as described in the specification, and pharmaceut... | 06/10/2003 |
| 6559337 | (Meth)acrylate, polymer, photoresist composition, and pattern forming process making use of the composition A photoresist composition contains a photoacid generator and a polymer represented by the following formula: ##STR1## wherein R4, R6 and R9 each represents a hydrogen atom or a methyl group, R5 and R7... | 05/06/2003 |
| 6455225 | Photoresist monomers having stability to post exposure delay, polymers thereof and photoresist compositions containing the same The present invention provides novel photoresist monomers, and photoresist polymers derived from monomers comprising the same. The photoresist monomers of the present invention are represented by the following formula: ##STR1## where Z1, Z... | 09/24/2002 |
| 6392104 | Adamantane derivatives and process for producing them In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): ##STR1## wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group, a cycloalkyl group; or ... | 05/21/2002 |
| 6392086 | Intermediates and process for producing fluorine-containing amino acid compound by using the same The present inventions relate to a (1S,5R,6S)- or (1SR, 5RS, 6SR)-3-fluoro-2-oxobicyclo[3.1.0]hex-3-ene-6-carboxylic acid derivative represented by Formula (1): ##STR1## [in the formula, R represents OR1 or NR1 R2, wherein... | 05/21/2002 |
| 6365768 | Interleukin-1 and tumor necrosis factors- modulators, syntheses of said modulators and methods of using modulators Novel compounds are disclosed that have the chemical structure of Formula (IIB), and its prodrug esters and acid-addition salts, and that are useful as Interleukin-1 and Tumor Necrosis Factor- modulators, and thus are useful in the treatment of var... | 04/02/2002 |
| 6265131 | Alicyclic dissolution inhibitors and positive potoresist composition containing the same A positive photoresist composition comprising a polymer, a photoactived agent and an dissolution inhibitor represented by the following formula (1): ##STR1## wherein R1 and R2 each independently is a hydroxyl group, a C1-8 | 07/24/2001 |
| 6258508 | Polymer using norbornene monomers with derivatives of cholic acid, deoxycholic acid or lithocholic acid and use thereof The present invention relates to a polymer prepared by synthesizing monomer having a derivative of cholic acid, deoxycholic acid or lithocholic acid bonded to norbornene, and then homopolymerizing these monomer, copolymerizing these monomer with maleic an... | 07/10/2001 |
| 6235447 | Photoresist monomers, polymers thereof, and photoresist compositions containing the same The present invention relates to novel monomers which can be used to form photoresist polymers and photoresist compositions using the same which are suitable for photolithography processes employing a far ultraviolet light source, copolymers thereof. Pref... | 05/22/2001 |
| 6222068 | Nitrocubanes An efficient direct functionalization of nitrocubanes has been achieved by irradiation of a solution in an oxalyl halide to yield halogenated and halocarbonylated derivatives of nitrocubanes.... | 04/24/2001 |
| 6084125 | Process for producing aliphatic acids using a reactor system having a shell and a tube reactor configuration to force circulation of reaction liquid A shell and tube heat exchanger reactor with forced circulation is used to improve heat and mass transfer for exothermic liquid--liquid, gas-liquid and gas-liquid-solid reactions. Enhanced productivity and selectivity are obtained.... | 07/04/2000 |
| 6051590 | Immunosuppressant tricyclic compounds The compounds of Formula I are useful as immunosuppressive agents.... | 04/18/2000 |
| 6037492 | Process for the industrial recovery of oleanolic and maslinic acids contained in the olive milling subproducts Process for the recovery of oleanolic and maslinic acids contained in the subproducts resulting from the milling and processing of olives or parts thereof, either proceeding from three-phase or two-phase presses. This process enables to obtain, by separat... | 03/14/2000 |
| 6010721 | Glycyrrhetinic-acid-like factor A human glycyrrhetinic-acid-like factor which inhibits certain enzymes in pathways of steroid hormone degradation is disclosed.... | 01/04/2000 |
| 5955501 | Protein kinase C modulators O Compounds having anti-inflammatory and other activities are disclosed. The compounds are derived from phorboids of the diterpene- and benzolactam-classes.... | 09/21/1999 |
