Famous Patents
British merchant Peter Durand invented the tin can in 1810.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8153841 | Compounds and their salts specific to the PPAR receptors and the EGF receptors and their use in the medical field The present invention relates to compounds comprising the general formula (I), in which R1 and R2, which may be identical or different, are selected from the group comprising —H or a linear or branched alkyl group having from 1 to 6 carbon at... | 04/10/2012 |
| 8058471 | Method for producing optically active hydroxycarboxylic acid derivatives or salts thereof The present invention has its object to provide a method for producing an optically active hydroxycarboxylic acid derivative which is an intermediate important for production of medicines, agrochemicals, chemical products, and so on. The production method of the pre... | 11/15/2011 |
| 7960582 | Process for the preparation and resolution of mandelic acid derivatives The present invention relates to a new process for the resolution of mandelic acid derivatives from racemic mandelic acid derivative mixtures by salt formation with chiral base cyclic amides; to the resolved mandelic acid cyclic amide salts (see, for example, formul... | 06/14/2011 |
| 7875744 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 01/25/2011 |
| 7598416 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 10/06/2009 |
| 7429676 | Process for preparing enantiomerically enriched 2-alkoxy-3-phenylpropionic acids The present invention relates to a process for preparing enantiomerically enriched, optionally substituted 2-alkoxy-3-phenylpropionic acids by asymmetrically hydrogenating alkoxycinnamic acids. ... | 09/30/2008 |
| 7427691 | Resolution of p-hydroxyphenyl-2-alkoxypropionic acids The present invention is aimed at a process for the preparation of enantiomerically enriched compounds of general formula (I). These are obtained by classical resolution of the corresponding acid using a chiral amino base in organic solvents. | 09/23/2008 |
| 7425649 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 09/16/2008 |
| 7368566 | Process and intermediates for preparing benzazepines Disclosed is a new process and intermediates for preparing benzazepines of Formula (I): wherein R1 and R2 are as defined herein. ... | 05/06/2008 |
| 7271197 | Phenethanolamine derivatives The present invention relates to novel compounds of formula (I), or a salt, solvate, or physiologically functional derivative thereof, to a process for their manufacture, to pharmaceutical compositions containing... | 09/18/2007 |
| 7217409 | Alkanoic acid derivatives A method for treating respiratory disorders comprises administering to a patient a pharmaceutical aerosol formulation comprising: (i) a compound of formula (I) or a salt or solvate thereo... | 05/15/2007 |
| 7144866 | Avermectin derivatives Provided is a compound represented by the general formula (I) or a salt thereof: wherein, —XY— represents —CH═CH— and the like, between R2 and the carbon atom at 5-posi... | 12/05/2006 |
| 7084177 | Comminuted form of(S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl] propanoic acid The present invention relates to a reduced particle size form of the compound (S)-2-ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl}ethoxy)phenyl]propanoic acid, as shown in formula (I), or a pharmaceutically acceptable salt thereof or a solvate of either thereof. The in... | 08/01/2006 |
| 7057038 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 06/06/2006 |
| 7022876 | Preparation of mandelic acid derivatives A process is provided for the preparation of mandelic acid derivatives. The process comprises the steps of: (a) stereoselectively cyanating a compound of Formula (2) to yield the corresponding cyanohydrin; | 04/04/2006 |
| 7002037 | Process for the preparation on enantiomerically enriched compounds The present invention relates to novel resolution methods, which are useful in the preparation of enantiomerically enriched intermediates which in their turn are useful in the prepartion of compounds with a pharmacological effect on the insulin resistance syndrome (... | 02/21/2006 |
| 6939988 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them Novel β-aryl-α-oxysubstituted alkylcarboxylic acids of the formula (I) and compositions containing them. The compounds have hypolipidemic, antihyperglycemic uses. ... | 09/06/2005 |
| 6867321 | Production method of hexahydrofurofuranol derivative, intermediate therefor and production method thereof The present invention provides a method for producing compound (XIV) useful as an intermediate for pharmaceutical agents efficiently and economically on an industrial scale without using ozone oxidation and highly toxic reagent, and an intermediate used for this met... | 03/15/2005 |
| 6864389 | Method for producing α-hydroxycarboxylic acid The present invention relates to: a method for producing α-hydroxycarboxylic acid, which comprises hydrolyzing cyanohydrin in the presence of a hydrocarbon solvent; a method for producing optically active α-hydroxycarboxylic acid, which c... | 03/08/2005 |
| 6844467 | Method for the production of glyceric acid Glyceric acid compounds of the formula (I) R1R2C(OH)—CR3(OH)—COOX (I) where R1, R2 and R3 are independently hydrogen, C1-12-alkyl, C6-12-aryl, C... | 01/18/2005 |
| 6825378 | Process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid The present invention provides a process for the synthesis of enantiomerically pure cyclohexylphenyl glycolic acid of formula (1). The present invention more particularly relates to a process using cyclohexylphenyl ketone for the synthesis of enantiomerically... | 11/30/2004 |
| 6781012 | Process for the preparation of optically and chemically highly pure (R)- or (S)-α-hydroxycarboxylic acids Process for the preparation of optically highly pure (R)- and (S)-α-hydroxycarboxylic acids, in which either isolated, impure (R)- and (S)-α-hydroxycarboxylic acids prepared by acidic hydrolysis of the (R)- and (S)- cyanohydrins obtained by enzyme-catalyzed additi... | 08/24/2004 |
| 6743944 | Process for producing optically active aminoalcohol An industrially advantageous process for producing optically active 4-amino-2-methylbutane-1-ol which is useful as an intermediate in synthesizing optically active medicines and pesticides. Racemic 4-amino-2-methylbutane-1-ol is treated with an optically active orga... | 06/01/2004 |
| 6743914 | Kinetic resolutions of chiral 2-and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomer... | 06/01/2004 |
| 6683207 | Production method of (R)-3 hydroxy-3-(2-phenylethyl) hexanoic acid and intermediate thereof The present invention relates to a production method of (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid which comprises optical resolution of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid with an optically active amine of the formula (VIII) ##STR1## ... | 01/27/2004 |
| 6660879 | 3-aryl-2-hydroxypropionic acid derivative I A novel 3-aryl-2-hydroxypropionic acid derivative, a process and intermediate for its manufacture, pharmaceutical preparations containing it and the use of the compound in clinical conditions associated with insulin resistance.... | 12/09/2003 |
| 6586463 | C16 unsaturated FP-selective prostaglandins analogs Compounds having the general structure: ##STR1## which are useful for the treatment of a variety of diseases and conditions, such as bone disorders.... | 07/01/2003 |
| 6586468 | ω-substituted phenyl-prostaglandin E derivatives and drugs containing the same as the active ingredient A ω-substituted phenyl-prostaglandin of formula (I), a process for the preparation thereof, a mediciament comprising it as active ingredient (all symbols have the same meaning as described in the specification). ##STR1## The compounds of the formula (I) ... | 07/01/2003 |
| 6576663 | 6-Keto prostaglandin F1 and analogs for treating dry eye Compositions and methods for the treatment of dry eye and related diseases utilizing 6-keto-PGF1 and its analogs are disclosed.... | 06/10/2003 |
| 6569901 | Alkynyl-substituted propionic acid derivatives, their preparation and use The present invention relates to compounds of formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 05/27/2003 |
| 6566547 | Fungicides This invention relates to derivatives of acrylic acid useful as fungicides, to processes for preparing them, to fungicidal compositions containing them, and to methods of combating fungi, especially fungal infections in plants, using them.... | 05/20/2003 |
| 6562966 | Kinetic resolutions of chiral 2- and 3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or d... | 05/13/2003 |
| 6562967 | Kinetic resolutions of chiral 2-and-3-substituted carboxylic acids One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or d... | 05/13/2003 |
| 6555577 | Compounds, their preparation and use The present invention relates to compounds of the general formula (I) ##STR1## The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).... | 04/29/2003 |
| 6492412 | Prevention of loss and restoration of bone mass by certain prostaglandin agonists Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disor... | 12/10/2002 |
| 6489504 | Malic acid and oxalacetic acid derivatives A malic acid or oxalacetic acid derivative is represented by the following formula (1): ##STR1## wherein ring Z is an alicyclic carbon ring; each of Ra and Rb is independently a hydrogen atom, a metal atom, or an organic group; and Y... | 12/03/2002 |
| 6451859 | C16 unsaturated FP-selective prostaglandins analogs Compounds having a structure according to the following formula: ##STR1## are effective in treating disorders such as bone disorders and glaucoma in a subject in need thereof.... | 09/17/2002 |
| 6437177 | -hydroxy, -amino, and halo derivatives of ଲ-sulfonyl hydroxamic acids as matrix metallopropteinases inhibitors The present invention provides a compound of formula I ##STR1## or pharmaceutical acceptable salts thereof wherein R1 is C4-12 alkyl, C4-12 alkenyl, C4-12 alkynyl, --(CH2)h --C3-8 | 08/20/2002 |
| 6376684 | Stereoselective process for alkyl phenylglycolic acids A process for preparing an alkyl phenylglycolic acid is disclosed. It follows the sequence of condensing a substituted acetaldehyde with mandelic acid to provide a 5-phenyl-1,3-dioxolan-4-one, which is condensed with an alkyl ketone or aldehyde to provide... | 04/23/2002 |
| 6362360 | 3-aryl-2-hydroxypropionic acid derivative III A novel 3-aryl-2-hydroxypropionic acid derivative, a process and intermediate for its manufacture, pharmaceutical prepartions containing it and the use of the compound in clinical conditions associated with insulin resistance.... | 03/26/2002 |
