Bizarre Patents
Behavior Modification Wristwatch
A wristwatch including a watch band and a watch body having an octagon shaped perimeter and being red in color and having the word STOP thereon to resemble a stop sign.
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| Number | Title | Issue Date |
| 8106235 | Biphenyl compound selective agonists of gamma RAR receptors Biphenyl compounds having the formula (I): are useful for preventing/treating pathologies linked to a deficiency of the activation of the RAR gamma receptor, e.g., for treating a pathology linked to a cell differentiation a... | 01/31/2012 |
| 8049034 | Biphenyl compound selective agonists of gamma RAR receptors Biphenyl compounds having the formula (I): are useful for preventing/treating pathologies linked to a deficiency of the activation of the RAR gamma receptor, e.g., for treating a pathology linked to a cell differentiation a... | 11/01/2011 |
| 8044236 | Carboxilic acid derivatives A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 r... | 10/25/2011 |
| 7446222 | Phenyl compounds Compounds of formula (I) or derivatives thereof: wherein A, B, Z, R1, R2a, R2b, Rx, R8, and R9 are as defined in the specification, a process for the prepara... | 11/04/2008 |
| 7304174 | CaSR antagonist A compound represented by the following formula (1), a pharmaceutically acceptable salt thereof or an optically active form thereof: wherein each symbol is as defined in the specification. A compound having a cal... | 12/04/2007 |
| 7265245 | Compounds useful for the treatment of diseases associated with the formation of amyloid fibrils The present invention provides new amyloidogenesis inhibiting compounds of formula (I): in which R1 is a —NRaRb group, where Ra and... | 09/04/2007 |
| 7232821 | (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, R1, R2, Rx, R8, R9 and n are as defined in the specification, a proc... | 06/19/2007 |
| 7217832 | 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is a hydrogen atom or an optionally substituted lower alkyl group; | 05/15/2007 |
| 7208524 | 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is a hydrogen atom or an optionally substituted lower alkyl group; | 04/24/2007 |
| 7169774 | Cephalotaxane derivatives and their processes of preparation and purification The present invention concerns a new general process for asymmetric hemisynthesis of harringtonines and their analogs, that are alkaloids used in chemotherapy. This process comprises direct esterification of a natural cephalotaxine with an acylating compound constit... | 01/30/2007 |
| 7151196 | Estrogen receptor modulators The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen receptors and as such may be useful for treatment or prevention of a v... | 12/19/2006 |
| 7037914 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I) (wherein all symbols are as defined in the specification), a non-toxic acid thereof or a hydrate thereof as ... | 05/02/2006 |
| 6936719 | Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating agents. ... | 08/30/2005 |
| 6869967 | Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in th... | 03/22/2005 |
| 6762315 | Method for producing (1,1′,4, 11″)-terphenyl compounds The invention relates to a method for producing [1,1′:4′,1″]-terphenyl compounds of the formula which comprises reacting a metal aryl of the formula with a boric ester ... | 07/13/2004 |
| 6699994 | Biaryl compounds as serine protease inhibitors Compounds of formula (I) are useful as inhibitors of trypsin like serine protease enzymes such as thrombin, factor VIIa, factor Xa, TF/FVIIa, and trypsin. These compounds could be useful to treat and/or prevent clotting disorders, and as anticoagulating a... | 03/02/2004 |
| 6586463 | C16 unsaturated FP-selective prostaglandins analogs Compounds having the general structure: ##STR1## which are useful for the treatment of a variety of diseases and conditions, such as bone disorders.... | 07/01/2003 |
| 6403638 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds having the formulas below, where R is H, lower alkyl, or a pharmaceutically acceptable salt, and where R1 represents i-propyl, t-butyl or n-butyl groups, have selective RXR retionoid agonist activity. ##STR1##... | 06/11/2002 |
| 6380430 | Biphenyl derivatives Novel compounds of the formula I ##STR1## in which X, R1, R2, R3, R4 and R5 have the meaning indicated in Patent Claim 1, are inhibitors of the coagulation factor Xa and can be employed for the prophy... | 04/30/2002 |
| 6376546 | Biphenyl-5-alkanoic acid derivatives and use thereof ##STR1## Compounds represented by general formula I or salts thereof, wherein n is an integer of 2 or 3; R represents a straight-chain or branched saturated alkyl group having 4 or 4 carbon atoms, a cyclopentyl group, a cyclohexyl group or the like, Y rep... | 04/23/2002 |
| 6369271 | Process for preparing derivatives of biphenyl-2-carboxylic acid The invention relates to a process for large-scale industrial production of biphenyl-2-carboxylic acid derivatives (I) ##STR1## wherein R1 and R2 may have the meanings given in the specification and claims.... | 04/09/2002 |
| 6369261 | Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 2 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##... | 04/09/2002 |
| 6326397 | Retinoid antagonists and use thereof The present invention relates to novel retinoid antagonists of the formula I ##STR1## wherein the dotted bond can be either hydrogenated or form a double bond; and, when the dotted bond forms a double bond, R1 is lower alkyl and R2 | 12/04/2001 |
| 6172239 | Substituted 1-phenyl-3-pyrazolecarboxamides active on neurotensin receptors, their preparation and pharamaceutical compositions containing them The invention relates to compounds of the formula ##STR1## The compounds have agreat affinity for the neurotensin receptors.... | 01/09/2001 |
| 6172112 | Retinoids and use thereof The present invention provides new retinoid compounds and uses of the compounds in humans and animals for chemoprevention of skin and/or breast cancer and for therapy of leukemia.... | 01/09/2001 |
| 6168776 | Alkyl, alkenyl and alkynyl Chrysamine G derivatives for the antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition Amyloid binding compounds which are non-azo derivatives of Chrysamine G, pharmaceutical compositions containing, and methods using such compounds to identify Alzheimer's brain in vivo and to diagnose other pathological conditions characterized by amyloido... | 01/02/2001 |
| 6162829 | (3R,4R)-Ɗ8 -tetrahydrocannabinol-11-oic acids useful as antiinflammatory agents and analgesics The present invention relates to non-psychoactive derivatives of tetrahydro-cannabinol, which exhibit anti-inflammatory, analgesic and leukocyte antiadhesion activities. The invention includes novel derivatives of (3R,4R)-Ɗ8 -tetrahydrocannabi... | 12/19/2000 |
| 6147224 | 2,4-pentadienoic acid derivatives having selective activity for retinoid X (RXR) receptors Compounds of Formula 1, Formula 2 or Formula 3 where X is O, S, or (CR1 R1)n where n is 0, 1 or 2; Y is a bivalent radical having Formula 4 or Formula 5 where o is an integer from 1 to 4 ##STR1## or Y is a bivalent ar... | 11/14/2000 |
| 6013827 | Compounds This invention relates to componds of formula I ##STR1## which are useful as PDE IV inhibitors and for treating diseases related thereto.... | 01/11/2000 |
| 5994379 | Bisaryl COX-2 inhibiting compounds, compositions and methods of use The present invention relates to inhibitors of COX-2, compositions which contain such compounds and methods of use. The compounds are represented by formula I: ##STR1## and include pharmaceutically acceptable salts and esters thereof.... | 11/30/1999 |
| 5952382 | Adamantyl-substituted retinoids and pharmaceutical/cosmetic compositions comprised thereof Pharmaceutically/cosmetically-active adamantyl-substituted retinoid compounds have the structural formula (I): ##STR1## wherein Ar is a radical having one of the formula (a) - (d): ##STR2## and are useful for the treatment of disorders and/or ai... | 09/14/1999 |
| 5939583 | Substituted 4-biphenyl-4-hydroxybutyric acid derivatives as matrix metalloprotease inhibitors Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula ##STR1## in which T is ... | 08/17/1999 |
| 5863926 | 4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds The present invention relates to novel 4,4-(disubstituted)cyclohexan-1-carboxylate monomers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammatory diseases and for inhibiting... | 01/26/1999 |
| 5827805 | Condensates of alkyl phenols and glyoxal and products derived therefrom Compositions represented by the structures ##STR1## where Ar represents an aromatic group, each R is independently a hydrocarbyl group, at least one R having more than 12 carbon atoms, a is 1 to 4, and R' is hydrogen or alkyl, are useful as lubricant... | 10/27/1998 |
| 5767310 | Phenoxyphenylacetic acid derivatives Phenoxyphenylacetic acids and derivatives of general structural formula (I) have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia... | 06/16/1998 |
| 5719184 | 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds The present invention relates to novel 3,3-(disubstituted)cyclohexan-1-carboxylate dimers and related compounds, pharmaceutical compositions containing these compounds, and their use in treating allergic and inflammatory diseases and for inhibiting the ... | 02/17/1998 |
| 5663413 | Biphenyl iodinated derivatives and their diagnostic use The invention relates to novel contrast media particularly useful for X-ray diagnostic investigations of human and animal body.... | 09/02/1997 |
| 5631293 | Preparation of amino acid-substituted benzoylguanidines as diagnostic agents Amino acid-substituted benzoylguanidines, a process for their preparation, their use as a medicament or diagnostic agent and a medicament containing them Benzoylguanidines of the formula I ##STR1## in which the radicals R(1) to R(5) have the meanings... | 05/20/1997 |
| 5475132 | Antifungal agents based on amides containing a phenyl group R3, R4 and R5, each represents a hydrogen or halogen atom (at least one of R3, R4 and R5 being other than hydrogen or halogen); optionally substituted amino; optionally halogenated or hydro... | 12/12/1995 |
| 5462954 | Substituted phenyl phenol leukotriene antagonists Antagonists having a substituted phenyl phenol or a substituted phenolic biphenyl structure, and various derivatives thereof, are specific leukotriene antagonists. Their structures, use and synthesis are disclosed. Also, pharmaceutical formulations are di... | 10/31/1995 |
