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Patent No. 5678617

Method and apparatus for making a drink hop along a bar or counter

A method for generating a drink which appears to hop from a remote spot on the bar or counter and take one or more leaps, before landing in a patron's glass.

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Class 562/460 - Two rings bonded directly to the same carbonyl


Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains two carbocyclic nuclei
No. of patents: 169
Last issue date: 10/28/2008


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NumberTitleIssue Date
7442832Painless injectable compositions containing salts of 2-arylpropionic acids
The invention relates to pharmaceutical compositions of alkylammonium salts of 2-aryipropionic acids, including ketoprofen, ibuprofen, naproxen and tiaprofenic acid. The compositions are suitable for parenteral administration arid, due to buffering at pH 8 to 9, cau...
10/28/2008
74230301-amino-phthalazine derivatives, the preparation and the therapeutic use thereof
A 1-amino-phthalazine derivative of general formula (I) wherein the substituents are as defined herein. Also disclosed are a method for preparing such compounds, intermediates for use in such method and medical treatments u...
09/09/2008
7381849Synthesis of asymmetric tetracarboxylic acids and dianhydrides
This invention relates to the compositions and processes for preparing 2,3,3′,4′-tetramethylbenzophenone and asymmetrical dianhydrides such as 2,3,3′,4′ benzophenone dianhydride (a-BTDA), and 3,4′-(hexafluoroisopropylidene)diphthalic anhydride (a-6FDA). a-...
06/03/2008
7348449Ligand antagonists of RAR receptors and pharmaceutical/cosmetic applications thereof
Novel ligand antagonists of the RAR receptors have the following structural formula (I): in which A is a CH2, CHOH, C═O or C═N—OH radical or a sulfur or selenium atom; B is a radical selected from among tho...
03/25/2008
7259188Methods and pharmaceutical compositions for treatment of anti-estrogen resistant breast cancer using RXR modulators
Methods and compositions for the treatment of anti-estrogen resistant breast cancer using retinoid compounds which are modulators of Retinoid X Receptors. ...
08/21/2007
7259186Salts of fenofibric acid and pharmaceutical formulations thereof
In one aspect, the present invention relates to a formulation in the form of molecular dispersion comprising i) fenofibric acid, a physiologically acceptable salt or derivative thereof and optionally other active substances, ii) a binder component comprising at leas...
08/21/2007
7238834Piperidine derivatives and process for their production
The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R1 is hydrogen or hydroxy; R2
07/03/2007
7098025Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor
This invention relates to the isolation and cloning of the promoter and other control regions of human PPARγ gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the level o...
08/29/2006
6998503Crystalline solid form of (2S,5Z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid
(2S,5Z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid is crystallized as an anhydrous, stoichiometric 1.5 HCl salt and a scaleable crystallization method is disclosed. The salt form was characterized and the absolute configuration of the chiral center was ...
02/14/2006
6977313Production process of 2,7-dibromofluorenone
A process is provided for the production of 2,7-dibromofluorenone. According to the process, a 2,7-dibromofluorene-contianing raw material is oxidized with molecular oxygen in the presence of a phase transfer catalyst such as a quaternary ammonium salt in a heteroge...
12/20/2005
6974872Process for production of piperidine derivatives
The present invention discloses processes for preparing piperidine derivative compounds of the formulae: wherein n is 0 or 1; R1 is hydrogen or hydroxy;
12/13/2005
6943275Process of preparing a disubstituted 9-alkylidenefluorene or a derivative thereof
The invention relates to a process of preparing disubstituted 9-alkylidenefluorenes and structure analogous compounds, to novel compounds and intermediates prepared by this process, their use for the preparation of conjugated polymers and copolymers thereof, and to ...
09/13/2005
6919458Process for production of piperidine derivatives
The present invention relates to a process for preparing piperidine derivative compounds of the formulae: wherein n is 0 or 1; R1 is hydrogen or hydroxy; ...
07/19/2005
6875885Process for the preparation of enantiomerically pure pyrethroid insecticides
A process for producing compounds of formula (VIIa) and (VIIb) wherein X is a leaving group; Y and Y1 are idependently Cl or Br; and Z is Cl, Br or a haloalkyl group which process comprises a) reacting a compound of formula (VII) wherein X, Y, Y1
04/05/2005
6855845Process for the preparing bromoisophithalic acid compound
The present invention relates to a process for preparing bromoisophthalic acid compounds, particularly 5-bromoisophthalic acid compounds and 4,5-dibromoisophthalic acid compounds comprising brominating an isophthalic acid compound of the general formula (1)
02/15/2005
6777442Diphenyl derivatives
The present invention relates to compounds of the general formula (I) in which X represents O, S, SO, SO2, CH2, CHF, CF2 or NR8, and Z represents a group of the formula
08/17/2004
6683205Synthesis of 2-aryl propenoic acid esters for the production of non-steroidal anti-inflammatory drugs
A method of producing a compound of the formula: ##STR1## and its pharmaceutically acceptable salts, wherein Ar is a substituted or unsubstituted aromatic or heteroaromatic group; comprising: (1) reacting a compound of the formula: ##STR2## wherein Ar...
01/27/2004
6677473Plasminogen activator inhibitor antagonists
Compounds and pharmaceutical compositions useful as plasminogen activator inhibitor (PAI) antagonists are provided. In particular, methods of antagonizing PAI with substituted and unsubstituted aryl and heteroaryl ethers and thioethers, benzils, benzyl et...
01/13/2004
6492424Glucocorticoid and thyroid hormone receptor ligands for the treatment of metabolic disorders
Novel glucocorticoid and thyroid receptor ligands as provided which have the general formula (I): ##STR1## in which R1 is an aliphatic hydrocarbon, an aromatic hydrocarbon, carboxylic acid or ester thereof, alkenyl carboxylic acid or ester ...
12/10/2002
6433196Production method of citalopram, intermediate therefor and production method of the intermediate
Citalopram can be industrially and economically produced and at a high yield by reacting a compound of the following formula [VI] with 3-(dimethylamino)propyl chloride in the presence of at least one of N,N,N',N'-tetramethylethylenediamine and 1,3-dimethy...
08/13/2002
6346546Biaromatic compounds and pharmaceutical and cosmetic compositions comprising them
Biaromatic compounds connected by a propynylene or ailenylene bond, corresponding to the formula (I). ##STR1##...
02/12/2002
6344585Preparation process of fluorenes
A tetrahydrofluorene, which is represented by the following formula (I) ##STR1## wherein R1 to R6 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms, or R1 and R2 are combi...
02/05/2002
6288265Phloroglucidic acid and derivatives as antibacterial agents
A series of phloroglucide derivatives are synthesized, which possess potent antibacterial activities. They include unsymmetrical phloroglucide analogs, phloroglucides attached to cephalosporins at the C-3' position, and 7-(phloroglucidamido)cephalosporins...
09/11/2001
6274608Compounds, their preparation and use
Disclosed are novel compounds of formula I ##STR1## wherein R1, R2, R3, L, X and Y are as defined in the specification. These compounds are useful in the treatment of conditions mediated by nuclear receptors, in particular...
08/14/2001
6235923Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity....
05/22/2001
6225494Trisubstituted phenyl derivatives having retinoid agonist or inverse agonist type biological activity
Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity....
05/01/2001
6121255Phloroglucide derivatives and their pharmceutical use
A phloroglucide derivative having the following formula: ##STR1## wherein Q is halogen; X is CH2 or C.dbd.O; Y is cephalosporin having a formula of ##STR2## wherein Ph is phenyl, Ac is acetoxy, or pharmaceutically acceptable salts ...
09/19/2000
6096920Preparation of carboxylic compounds and their derivatives
Palladium-catalyzed arylation of an olefin (e.g., ethylene) with an aromatic halide (e.g., 2-bromo-6-methoxynaphthalene, m-bromobenzophenone, or 4-isobutyl-1-bromobenzene) is conducted in specified media. After a special acid or base phase separation proc...
08/01/2000
6043279Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass...
03/28/2000
6037488Trisubstituted phenyl derivatives having retinoid agonist, antagonist or inverse agonist type biological activity
Compounds of the formula ##STR1## where the symbols have the meaning defined in the specification, have retinoid, retinois antagonist or retinoid inverse agonist type biological activity....
03/14/2000
6001877Phenylalkan(en)oic acid
The phenylalkan(en)oic acids of the formula: ##STR1## as defined herein, posses an antagonistic activity on leukotriene B4....
12/14/1999
5962731Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass...
10/05/1999
5932763Inhibition of matrix metalloproteases by 2-(ω-arolalkyl)-4-biaryl-4-oxobutyric acids
The present invention provides pharmaceutical compositions and methods for treating certain conditions comprising administering an amount of a compound or composition of the invention which is effective to inhibit the activity of at least one matrix metal...
08/03/1999
5922904Bulk dyeing using quinophthalone dyestuffs
Benzoyl phthalic acids of the formula ##STR1## useful as intermediates in the preparation of quinophthalone dyestuffs....
07/13/1999
5886022Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula ##STR1## wherein each T...
03/23/1999
5883294Selective thyroid hormone analogs
Selective thyroid hormone agonists are disclosed that are highly selective for the TRଲ subtype with high binding affinity. Methods of using such agonists and pharmaceutical compositions containing them are also disclosed, as are novel procedures for...
03/16/1999
5808124O- or S-substituted dihydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity
Compounds of the formula ##STR1## where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity....
09/15/1998
5739352Process for preparing carboxylic acids
This invention relates to a process for preparing carboxylic acids by oxidizing an aldehyde with a peracid in the presence of an amine and/or amine N-oxide catalyst selected from the group consisting of a substituted or unsubstituted alkyl amine, alkyl am...
04/14/1998
5677469Process for resolving chiral acids with 1-aminoindan-2-ols
A process for the full or partial resolution of a mixture of enantiomers of a genus of chiral carboxylic acids is disclosed. The process uses a pure enantiomer of 1-aminoindan-2-ol as the resolving agent and achieves separation of the diastereomeric salts...
10/14/1997
5583221Substituted fused and bridged bicyclic compounds as therapeutic agents
Compounds having the formula ##STR1## methods for using such compounds to inhibit protein kinase C in animals, including man are useful as inhibitors of protein kinase C. Also disclosed are pharmaceutical compositions including such compounds and com...
12/10/1996
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