Class 562/448 - Plural nitrogens

Subclass of Class 562 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid contains more than one covalently
No. of patents: 171
Last issue date: 04/13/2010

«First «Previous1 2 3 4 5 Next»Last»

Number	Title	Issue Date
7696377	Stabilizer and method for stabilizing hydroxylamine, and stabilized hydroxylamine solution It is the objective to provide a method of stabilizing hydroxylamine at a high temperature and a high concentration or in a case that metal impurities such as Fe got mixed therewith, and a stabilized hydroxylamine solution. A method for stabilizing hydroxylamine rel...	04/13/2010
7692038	Crystalline forms The present invention relates to crystalline forms of (3S)-3-[N—(N′-(2-tert-butylphenyl)oxamyl)alaninyl]amino-5-(2′,3′,5′,6′-tetrafluorophenoxy)-4-oxopentanoic acid (see formula I). The invention further relates to pharmaceutical compositions comprising ...	04/06/2010
7662994	Method for the preparation of crystalline dexloxiglumide and products obtained The present invention describes a novel method for the purification of dexloxiglumide by crystallization from isopropyl ether which permits the production, in a reproducible manner, of a product with morphological and particle-size characteristics such as to favor i...	02/16/2010
7592482	Process for the preparation of contrast agents The present invention refers to a process for preparing a compound of formula (I) through a carboxymethylation reaction occurring in the presence of a suitable alkylating agent and of a base, without the need of monitoring the pH of the reaction environment. The com...	09/22/2009
7351864	Process for preparation of Mannich condensation products useful as sequestering agents The present invention is directed to a process for preparing Mannich condensation product sequestering agents or mixtures of Mannich condensation product sequestering agents for use in fuels and lubricating oils. ...	04/01/2008
7205435	Type B botulism toxin inhibitors Novel compounds of general formula (I), are provided with inhibitory properties for the type B botulism toxin activity, along with methods for preparation thereof and corresponding pharmaceutical compositions. ...	04/17/2007
7205336	β-secretase inhibitors The present invention provides compounds that are inhibitors of the proteolytic activity of the enzyme β-secretase, pharmaceutically acceptable salts of the compounds, pharmaceutical compositions comprising the compounds, processes for making the compounds, and met...	04/17/2007
7202381	Compounds as opioid receptor modulators This invention is directed towards novel compounds as opioid receptor modulators, antagonists, and agonists useful for the treatment of opioid modulated disorders such as pain and gastrointestinal disorders. ...	04/10/2007
7199265	Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of m...	04/03/2007
7183430	Compounds which can block the response to chemical substances or thermal stimuli or mediators of inflammation of nociceptors, production method thereof and compositions containing same The invention relates to compounds having formula (I), which can block the response to chemical substances or thermal stimuli or mediators of inflammation of nociceptors, a production method thereof and compositions containing same. According to the invention, Ar is...	02/27/2007
7153869	Substituted amino acids as erythropoietin mimetics This invention relates to a series of substitituted amino acids of Formula I pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molec...	12/26/2006
7145040	Process for the preparation of amino acids useful in the preparation of peptide receptor modulators The present invention provides process useful for the preparation of intermediates which are useful in the preparation of amino acids useful in preparing peptide receptor modulators, for example agonists or partial agonists of such peptide receptors. Such peptide re...	12/05/2006
6855706	Phenylalanine derivatives Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents for various diseases concerning α 4 integrin. ...	02/15/2005
6835851	Process for synthesizing N-(mercaptoacyl) amino acid derivatives from alpha-substituted acrylic acids The instant invention relates to a process for preparing a compound of formula (I): said process comprising a step (B) which consists in performing a Michael addition of a thioacid RS4H on to an α-substituted acrylami...	12/28/2004
6806365	N-alkanoylphenylalamine derivatives Compounds of the formula: are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related t...	10/19/2004
6777440	HIV integrase inhibitors The present invention relates to the inhibition of HIV integrase, and to the treatment of AIDS or ARC by administering compounds of the following formula, or a tautomer of said compound, or a pharmaceutically acceptable salt, solvate or prodrug thereof: ...	08/17/2004
6743929	Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors Sulfonamide-containing hydroxyethylamine compounds are effecive as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. ...	06/01/2004
6610710	Phenylalanine derivatives Phenylalanine derivatives of the following formula and analogues thereof have an antagonistic activity to 댔댧 integrin and a selectivity toward 댔댡 integrin. They are used as therapeutic agents for various diseases to which ...	08/26/2003
6586403	Treating allergic reactions and inflammatory responses with tri-and dipeptides This invention relates to methods and compositions of tripeptides and dipeptides having anti-inflammatory activities that can be used for the treatment of allergic and inflammatory reactions. A peptide of the formula: X-R.sub. 1 -R2 -R3	07/01/2003
6528655	Aromatic derivatives with HIV integrase inhibitory properties A compound of formula I' ##STR1## and pharmaceutically acceptable derivatives thereof including, for example, where applicable or appropriate pharmaceutically acceptable salts thereof. Ar and Ar' are aromatic or aryl type groups. The compounds have HIV ...	03/04/2003
6362165	Hydroxyphenyl derivatives with HIV integrase inhibitory properties An hydroxyphenyl derivative selected from the group consisting of a compound of formula ##STR1## and when a compound of formula I comprises a carboxylic acid group pharmaceutically acceptable salts thereof and when a compound of formula I comprises a...	03/26/2002
6350907	Matrix metalloprotease inhibitors Compounds of formula (I): ##STR1## or pharmaceutically acceptable salts thereof, or solvates of either entity, wherein the substituents have the values described herein, are useful as matrix metalloprotease (MMP) inhibitors...	02/26/2002
6310078	Substituted amino acids as erythropoietin mimetics This invention relates to a series of substituted amino acids of Formula I ##STR1## pharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules which bind to the erythropoieti...	10/30/2001
6284914	Highly water-soluble metalloproteinase inhibitors New compounds of general formulae (III), (IV) and (V). ##STR1##...	09/04/2001
6274733	Process and intermediates in the synthesis of 5-(3-[exo-bicyclo[2.2. 1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydro-pyrimidin-2(1H)-one This invention relates to novel processes for preparing the pharmaceutically active compound 5-(3-[(2S)-exo-bicyclo[2.2. 1]hept-2-yloxy]-4-methoxyphenyl)-3,4,5,6-tetrahydropyrimidin-2(1H)-one and its corresponding 2R enantiomer and for preparing cert...	08/14/2001
6255285	Phenethylamine derivatives The present invention has as its object providing phenethylamine derivatives that typically function as a motilin receptor antagonist and which are useful as medicines. The invention provides compounds represented by the general formula (1): ##STR1##...	07/03/2001
6242607	Disubstituted glutarimide method for preparing same, and use thereof The invention relates to glutarimides of formula (I): ##STR1## in which Ar represents a phenyl non substituted or substituted one or more times with one of the substituents selected from a halogen atom, a hydroxyl, a (C1 -C4)alkoxy, ...	06/05/2001
6229011	N-aroylphenylalanine derivative VCAM-1 inhibitors Compounds of the formula: ##STR1## are disclosed which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 ...	05/08/2001
6197750	C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases This invention is directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as to the use of such compositions in the treatment of patients su...	03/06/2001
6162947	Process for the preparation of 4-carboxy-5, 8,11-tris (carboxymethyl)-phenyl-2-oxa-5, 8 11-triazatridecan A novel a process for the preparation of the chelating agent of formula (I) ##STR1## 4-carboxy-5,8,11-tris(carboxymethyl)-1-phenyl-2-oxa-5,8,11-triazatridecan- 13-oic acid, commonly named BOPTA....	12/19/2000
6153591	Dipeptide caspase inhibitors and the use thereof The present invention is directed to novel dipeptides represented by the general Formula I: ##STR1## where R1 -R2 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are pote...	11/28/2000
6127341	Compounds with growth hormone releasing properties Compounds of the general formula I ##STR1## compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are described....	10/03/2000
6100423	Amino benzenepropanoic acid compounds and derivatives thereof The present invention is directed to compounds of the formula ##STR1## where R1 is BOC or H, R is H or lower alkyl; X and Y are the same or different halo atoms selected from the group consisting of Cl, Br or I and pharmaceutically accepta...	08/08/2000
6010733	Aspartylamide derivatives and sweeteners Novel aspartylamide derivatives such as N-(଱-L-aspartyl-(1R,2S,4S)-1-methyl-2-hydroxy-4-phenylhexylamide, N-଱-7(N'-3,3-dimethylbutylaspartyl)-(1R,2S,4S)-1-methyl-2-hydroxy-4- phenylhexylamide) and the like, and a sweetener containing the a...	01/04/2000
5965588	Sulfonylalkanoylamino hydroxyethylamimo sulfonamides useful as retroviral protease inhibitors Sulfonamide-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease....	10/12/1999
5929112	Derivatives of N,N'-di (carboxyalkyl) alkylene di-or triamine The derivatives of N,N'-di(aralkyl)-N,N'-di(carboxyalkyl) alkylene di- or triamine and N-(aralkyl)-N'-(carboxyalkyl)-N'N'-di(carboxyalkyl) alkylene di- or triamine of the formula: ##STR1## and the salts and metallic complexes thereof are disclosed. U...	07/27/1999
5840974	Metalloproteinase inhibitors Compound of formula (I) ##STR1## wherein Ar represents an optionally substituted phenyl or heteroaryl group, m is 1 or 2, n is 0, 1, 2, 3 or 4, X represents --COOH or --CONHOH and R1, R3 and Y are as defined in the specification...	11/24/1998
5770620	Aryl acrylic acid derivatives useful as protein tyrosine phosphatase inhibitors The present invention provides novel protein tyrosine phosphatase modulating compounds having an aryl acrylic acid structure, compositions comprising the compounds, and methods of making and using the same....	06/23/1998
5767085	Compounds with growth hormone releasing properties Compounds of the formula A--B--C--D(--E)p are used to stimulate the release of growth hormone from the pituitary....	06/16/1998
5756825	Hydroxamic acid-based bifunctional chelating compounds The present disclosure details the preparation of hydroxamic-acid based bifunctional chelators and their use in conjugating metal ions to proteins and nucleic acids for tumor or tissue imaging or therapy purposes. Some preferred aspects of the disclosure ...	05/26/1998

«First «Previous1 2 3 4 5 Next»Last»

PatentStorm

Bizarre Patents

PatentStorm News

Class 562/448 - Plural nitrogens