Bizarre Patents
An aircraft having vertical takeoff and landing capability provided with at least first and second laterally extending paddle wheels rotatable on a central axis perpendicular to the longitudinal axis of the aircraft fuselage and between its nose and tail.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7432388 | Disubstituted chalcone oximes having RARγ retinoid receptor antagonist activity Compounds of the formula where the variables have the values described in the specification are antagonists of RARγretinoid receptors. ... | 10/07/2008 |
| 7427690 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex ... | 09/23/2008 |
| 7420083 | Substituted aryloximes The present invention relates to substituted aryl oximes and methods of using them. ... | 09/02/2008 |
| 7399577 | Halogenated oxime derivatives and the use thereof Compounds of the formula (I) or (II) wherein R1 is C1-C10haloalkylsulfonyl, halobenzenesulfonyl, C2- C10haloalkanoyl, halobenzoyl; R2 is halogen or C1-C10 haloalkyl; Arl is pheny... | 07/15/2008 |
| 7371896 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 05/13/2008 |
| 7319160 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 01/15/2008 |
| 7312031 | Alpha-complementation viral fusion assay The present invention relates to the use of an alpha complementation assay as a quick, effective, and safe method for the detection of cell fusion mediated by viral proteins. Additionally, the method disclosed herein permits the identification of inhibitors of cell ... | 12/25/2007 |
| 7265220 | Amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative Compound of formula (I): wherein: R1 represents aryl, heteroaryl or alkyl which is optionally substituted, or a group of formula —(CO)—CR6R7NR8R9 ... | 09/04/2007 |
| 7265136 | Substituted stilbene compounds with vascular damaging activity A compound for use in inducing necrosis in vascular tissue of a tumor in an animal. The compound contains a first moiety which is a cis-stilbene moiety and a second moiety which is an inhibitor of the formation or action of nitric acid. Also, a method for inducing n... | 09/04/2007 |
| 7220781 | Meta-benzamidine derivatives as serine protease inhibitors Compounds of formula I in which R1, R2, R3, each X, L, Y, Cy, Lp, D and n have the meanings as set out in the specification, and corresponding compounds in which the unsubstituted... | 05/22/2007 |
| 7189878 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 03/13/2007 |
| 7186749 | Pyrrolo-naphthyl acids and methods for using them The present invention relates to pyrrolo-naphthyl compounds of the formula and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders. ... | 03/06/2007 |
| 7030133 | Inhibitors of formation of advanced glycation endproducts (AGEs) The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood an... | 04/18/2006 |
| 7015352 | Pro drugs for selective drug delivery Prodrug compounds capable of permeating a desired biological compartment and releasing a biologically active molecule in active form to effect a therapeutic functional change in the compartment to which it is introduced. ... | 03/21/2006 |
| 6964982 | Compounds, compositions and methods for preventing neurodegeneration in acute and chronic injuries in the central nervous system The present invention provides compositions and methods for prevention and prophylaxis of neurological diseases accompanied by neuronal death. The invention includes synthesis of 5-benzylamino salicylic acid (BAS) and its derivatives. BAS and its derivatives protect... | 11/15/2005 |
| 6949534 | Cell adhesion inhibitors The present invention relates to novel compounds that are useful for inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies. This invention also relates to pharmaceutical formulations comprising these compounds and methods of using them fo... | 09/27/2005 |
| 6908934 | Therapeutic compounds for treating dyslipidemic conditions Compounds of Formula I and the pharmaceutically acceptable salts and esters thereof, wherein Z is selected from the group consisting of: (a) Formula Ia | 06/21/2005 |
| 6787668 | 2-amino-4,5 heptenoic acid derivatives useful as nitric oxide synthase inhibitors The present invention is directed to a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is selected from the group consisting of H and methyl; and R2 i... | 09/07/2004 |
| 6740682 | Meta-benzamidine derivatives as serine protease inhibitors The novel compound 3-amidinobenzoyl-D-phenylglycine-3-phenylanilide is useful as a serine protease inhibitor. ... | 05/25/2004 |
| 6730807 | Carbodiimides with carboxyl or carboxylate groups Compounds containing carbodiimide units and carboxyl or carboxylate groups (compounds V), derived from a) aliphatic or araliphatic C4 to C20 polyisocyanates (component a) b) amino carboxylic acids or amino carboxylic salts (compon... | 05/04/2004 |
| 6710056 | Amidinophenylpyruvic acid derivatives An amidinophenylpyruvic acid derivative of the following formula, analogs thereof and pharmaceutically acceptable salts thereof have an excellent antagonistic effect against activated blood coagulation factor VII. ... | 03/23/2004 |
| 6627769 | RGD-analog non-peptidic molecules having anti-adhesive, anti-migration and anti-proliferative effects Novel molecules without intramolecular peptidic bonds, able to mimic the RGD peptide, containing ARG-GLY-ASP motif "arginine-glycine-aspartic acid" (that is a potent inhibitor, in vivo and in vitro, of cellular adhesion) In vitro experimentation demonstra... | 09/30/2003 |
| 6627580 | Chelating agents and their manganic chelates Chelating agents (chelants) of the general structure: ##STR1## wherein: n=2-4 ##STR2## whereby at least two of X are of formula III Y=COOH, --PO3 H2 or o-hydroxyphenyl R1, R2 and R3 are independent... | 09/30/2003 |
| 6608196 | Process for solid supported synthesis of pyruvate-derived compounds Provided are processes for synthesizing structurally diverse pyruvate-derived compounds using a parallel approach on a solid phase support. Examples of such a solid phase support include resins which have also been used in solid phase peptide synthesis.... | 08/19/2003 |
| 6605740 | Fluorescent dyes for the labeling of biological substrates This invention provides a new class of squaraine dyes having moieties which serve for the covalent attachment to biological substrates and resulting in the fluorescent labeling of the substrates. The labeled substrates are intended for use in analytical t... | 08/12/2003 |
| 6603041 | Bicyclic enamide derivatives Enamide derivatives of formula (1) are described: ##STR1## wherein R1 is a group Ar1 L2 Ar2 Alk- in which Ar1 is an optionally substituted aromatic or heteroaromatic group, L2 is a covalent... | 08/05/2003 |
| 6599938 | Compounds having MIF antagonist activity There is disclosed a genus of optionally substituted Schiff base condensation products (and the carba analogs thereof) comprising an amino acid component and a benzaldehyde component, that have MIF (macrophage migration inhibitory factor) antagonist activ... | 07/29/2003 |
| 6548694 | N-(4-carbamimidoyl-phenyl)-glycine derivatives N-(4-carbamimidoyl-phenyl)-glycine derivatives have the formula: ##STR1## wherein X and R1 to R5 are as defined herein, and includes hydrates or solvates and/or physiologically acceptable salts thereof and/or physiologically acceptab... | 04/15/2003 |
| 6518435 | Process for the preparation of oxyiminoalkanoic acid derivatives The present invention provides, as an industrially advantageous production method, a method of producing a compound represented by the formula (III) ##STR1##... | 02/11/2003 |
| 6500951 | Process for preparing pyridazin-3-on derivatives A pyridazin-3-on derivative of the formula (1): ##STR1## in which R2 is a hydrogen atom or a C1 -C3 alkyl group, R3 is a hydrogen atom or a C1 -C3 alkyl group, and Q is an optionally substi... | 12/31/2002 |
| 6479524 | Substituted aryl and heteroaryl derivatives, their production and their use as medicines Compounds that prolong thrombin time. Exemplary are: (a) rac-4-{3-[5-ethoxycarbonylmethyl-2-methyl-4-(2-methyl-pyrrolidinocarbonyl) -phenyl]-propargylamino}benzamidine, (b) rac-4-{3-[2,5-dimethyl-4-(2-methyl-pyrrolidinocarbonyl)-phenyl]-propargyla mino... | 11/12/2002 |
| 6451859 | C16 unsaturated FP-selective prostaglandins analogs Compounds having a structure according to the following formula: ##STR1## are effective in treating disorders such as bone disorders and glaucoma in a subject in need thereof.... | 09/17/2002 |
| 6395737 | Malonic acid derivatives, processes for their preparation, for their use and pharmaceutical compositions containing them New compounds for the inhibition of blood clotting proteins, and more particularly, to malonic acid derivatives of the formula I, ##STR1## wherein R(1), R(2), R(3), R(4), R(5), and R(6) have the meanings indicated in the claims. The compounds of formula I... | 05/28/2002 |
| 6348593 | Process for preparing folic acid A process for preparing folic acid, which comprises reacting a tetraalkoxypropanol of the general formula I, ##STR1## in which the substituents R are C1 -C4 -alkyl, with triaminopyrimidone of the formula II and p-aminobenzoyl-L-gluta... | 02/19/2002 |
| 6348627 | Aryl and heteroarylcyclopropyl oxime ethers and their use as fungicides Compounds with fungicidal and insecticidal properties having formula ##STR1## wherein X is N or CH; Z is O, S or NR8 ; A is hydrogen, halo, cyano, (C1 -C12)alkyl, or (C1 -C12)alkoxy; R1 and ... | 02/19/2002 |
| 6344483 | Halogenated amidino amino acid deviratives useful as nitric oxide synthase inhibitors The current invention discloses halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors, and pharmaceutically acceptable salts thereof.... | 02/05/2002 |
| 6340420 | Methods of treating the oxidation mixture of hydrocarbons to respective dibasic acids This invention relates to methods of controlling the oxidation of hydrocarbons to respective dibasic acids, such as adipic acid for example, by removing the catalyst from the reaction mixture, outside the reaction zone, after the oxidation has taken place... | 01/22/2002 |
| 6337306 | Phenoxyacetic acid derivatives and their use as herbicides Phenoxyacetic acid derivatives of the formula: ##STR1## wherein R1, R2, Xn and A are as defined herein, and a process for preparing the derivatives. The derivatives are used as herbicides.... | 01/08/2002 |
| 6337350 | Inhibitors of formation of advanced glycation endproducts (AGEs) Derivatives of aryl and heterocyclic ureido and aryl and heterocyclic carboxamido phenoxy isobutyric acids have been found to inhibit the nonenzymatic glycation of proteins which often results in formation of advanced glycation endproducts and crosslinks.... | 01/08/2002 |
| 6323227 | Substituted N-[(aminoiminomethyl or aminomethyl)phenyl]propyl amides This invention relates to compounds of formula ##STR1## which inhibit Factor Xa, to pharmaceutical compositions containing the compounds, and to the use of the compounds for the treatment of patients suffering from conditions which can be ameliorated by t... | 11/27/2001 |
