Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 6702890 | Process for the production of fly ash slurry The present invention describes an improved method for forming fly ash slurry by mixing fly ash and water with an additive containing 0.5-2 wt % ammonium salt of humic acid and 0.03 to 0.05 wt % tannin extract. The product slurry does not require large am... | 03/09/2004 |
| 5162577 | Process for lithiation of 1,3-bis(trifluoromethyl)benzene A novel process for the lithiation of 1,3-bis(trifluoro-methyl)benzene in a solvent is described, said process comprising carrying out the lithiation with the lithium salt of an amine of the general formula R1 R2 NH ... | 11/10/1992 |
| 4695648 | Novel arylacetic acid derivatives A compound having a potentially inhibitory effect on 15-hydroxy-prostaglandin dehydrognase (PGDH) and having the formula ##STR1## in which R1 and R2 are hydrogen or lower alkyl; R3 is hydrogen, lower alkyl or substituted o... | 09/22/1987 |
| 4683325 | Leukotriene antagonists Compounds having the formula: ##STR1## are antagonists of leukotrienes of C4, D4 and E4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory and c... | 07/28/1987 |
| 4603209 | Fluorescent indicator dyes for calcium ions The present invention discloses a new class of highly fluorescent indicator dyes that are specific for calcium ions. The new fluorescent indicator dyes combine a stilbene-type fluorophore with a tetracarboxylate parent Ca2+ chelating compound h... | 07/29/1986 |
| 4568695 | 2-Amino-3-benzoyl-phenethylalcohols and intermediates therefor Novel 2-amino-3-benzoylphenethylalcohols are provided having the formula: ##STR1## wherein; X is hydrogen, loweralkyl, loweralkoxy, halogen or trifluoromethyl, and Y is hydrogen, loweralkyl, loweralkoxy, halogen, trifluoromethyl, --S--loweralkyl, ... | 02/04/1986 |
| 4446078 | Process for the preparation of ,-difluoroalkyl-thiophenyl ketones A process for the preparation of ,-difluoroalkoxy or ,-difluoroalkylthiophenyl ketones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a carboxylic acid, a precursor or a derivative of this acid ... | 05/01/1984 |
| 4407823 | Novel phenylacetic acid derivatives Phenylacetic acid derivatives of the formula ##STR1## wherein n is an integer of 2 to 5; ##STR2## R1 is hydrogen, halogen, trifluoromethyl, nitro or amino; R2 and R3 each independently is hydrogen or lower alkyl;... | 10/04/1983 |
| 4379765 | Pyrazolobenzazepines There are presented compounds of the formulas ##STR1## wherein R1 is hydrogen or lower alkyl; R2 and R3 are selected from the group consisting of hydrogen, lower alkyl, C2 to C7 carboxylic acids,... | 04/12/1983 |
| 4254146 | 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters 3-Benzoyl-2-nitrophenylacetic acids, metal salts, amides and esters are disclosed having the formula: ##STR1## wherein R1 is hydrogen or lower alkyl; R2 is OH, OM, O-lower alkyl, NH2, NH-lower alkyl or N,N-dilower alk... | 03/03/1981 |
| 4224341 | 5-Substituted indan-2 carboxylic acid and functional derivatives 5-Substituted indan-2-carboxylic acids and functional derivatives thereof having inflammation-reducing properties have the general formula ##STR1## in which R is a phenyl, phenyl-lower alkenyl, phenyl-lower alkyl, phenyl substituted by at least one o... | 09/23/1980 |
| 4179515 | Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X4 and X5 are hydrogen or lower alkyl, Y is hydrogen, hydroxy, etherified ... | 12/18/1979 |
| 4126635 | 2-Amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: ##STR1## wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower-alkyl, sodium or potassium, R2 is hydrogen, halogen or lower alkox... | 11/21/1978 |
| 4119783 | 3'Lower alkylcarbonyl oxanilic acid esters Pharmaceutical compositions having as the active agent a compound of the formula ##STR1## useful for preventing allergic manifestations in sensitized mammals and novel compounds.... | 10/10/1978 |
| 4096176 | Benzoylbenzoic acids Substituted 3,3-diphenylphthalides, useful as color precursors, particularly in the art of pressure-sensitive duplicating systems, are prepared by condensing substituted 2-benzoylbenzoic acids with substituted anilines.... | 06/20/1978 |
| 4072705 | Phenylmethylphenoxy propionic acid esters Compounds of the formula ##STR1## in which A is lower alkyl, or a substituted or unsubstituted phenyl, thienyl, furyl, indolyl or thiaindolyl radical, R, X4 and X5 are hydrogen or lower alkyl, Y is hydrogen, hydroxy, etherified ... | 02/07/1978 |
| 4065477 | Process for preparing highly pure 1-nitroanthraquinone 1-Nitroanthraquinone is produced in highly pure form by a process comprising the steps of partially oxidizing 3-nitro-o-xylene (I) to 2-methyl-3-nitrobenzoic acid (II) converting II to 2-methyl-3-nitrobenzoyl halide (III), converting III to the novel inte... | 12/27/1977 |
| 4058559 | 4-Aroyl-substituted phenoxy acetic acids This invention provides 4-aroyl substituted phenoxy acetic acids and tetrazoles of the formula ##STR1## wherein R is a phenyl ring, a substituted phenyl ring, or naphthyl; R1 is --CH2 COOH or methyl tetrazole, and X1 ... | 11/15/1977 |
| 4045576 | Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: ##STR1## wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower-alkyl, sodium or potassium, R2 is hydrogen, halogen or lower alkox... | 08/30/1977 |
| 4036838 | Process for the production of nitro derivatives of aromatic compounds Nitroderivates of aromatic compounds which are difficult to nitrate, can readily be obtained by nitration providing that the aromatic compound is treated with nitric acid or another nitrating agent in the presence of aliphatic or cycloaliphatic hydrocarbo... | 07/19/1977 |
| 3951999 | Anti-inflammatory 1,2-benzisoxazole derivatives 3-Phenyl substituted 1,2-benzisoxazole acetic and propionic acid derivatives with anti-inflammatory activity.... | 04/20/1976 |
| 3931301 | Benzophenone derivatives and process for their preparation III The present invention relates to pharmacologically valuable new benzophenone derivatives having a pronounced sedative action on the central nervous system and some of which also possess muscle-relaxing and aggression-inhibiting properties. These new deriv... | 01/06/1976 |
