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A vest or belt is integrally formed with tubular, pet receiving passageways which extend around the wearer's body and terminate in pocket-like chambers for feeding and retrieval.
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| Number | Title | Issue Date |
| 8247602 | Antagonists of prostaglandin Dreceptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination ... | 08/21/2012 |
| 8193386 | Crystalline form of (S)-1-phenylethylammonium (R)-diphenylmethanesulphinyl-acetate Novel crystalline hydrate form of (S)-1-phenylethylammonium (R)-diphenyl-methanesulphinyl-acetate and its use in a process for the preparation of (R)-benzhydrylsulphinylacetamide. ... | 06/05/2012 |
| 8071807 | Antagonists of prostaglandin D2 receptors Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination ... | 12/06/2011 |
| 8013183 | Alpha ketoamide compounds as cysteine protease inhibitors The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compo... | 09/06/2011 |
| 7956216 | Alpha-helical mimetics Benzoyl urea derivatives that are alpha helical peptides mimetics that mimic BH3-only proteins, compositions containing them, their conjugation to cell-targeting-moieties, and their use in the regulation of cell death are disclosed. The benzoyl urea derivatives are ... | 06/07/2011 |
| 7947850 | Process for the preparation of 3,4-disubstituted-thiazolidin-2-ones The present invention is directed to practical high-yielding synthetic processes for preparing 3,4-disubstituted-thiazolidin-2-ones, which do not compromise the absolute stereochemical integrity of the compounds. The present invention is also directed to novel compo... | 05/24/2011 |
| 7910770 | Fc receptor modulating compounds and compositions The present invention provides compounds capable of binding to an Fc receptor and modulating Fc receptor activity comprising a core lipophilic group in the form of an Aryl ring substituted with a group rich in p-electrons. The invention further provides for a method... | 03/22/2011 |
| 7847119 | Drug conjugates A compound having the formula Y-A-Z, wherein: A is a phenyl group which is unsubstituted or substituted; Y and Z are substituents at adjacent positions on ring A; Y represents: | 12/07/2010 |
| 7709682 | Lysine salts of 4-((phenoxyalkyl)thio)-phenoxyacetic acid derivatives The present invention is directed to a novel lysine salts, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by PPAR delta. The present invention is further directed to a novel process for the preparatio... | 05/04/2010 |
| 7423176 | Bicyclic aromatic sulfinyl derivatives The present invention provides compounds of the structure: wherein the constituent members are defined herein, including pharmaceutical compositions thereof and methods of treating diseases therewith. ... | 09/09/2008 |
| 7411031 | Synthesis of polyanhydrides The present invention provides a method for forming compounds of Formula HO—C(═O)R1—X—R2—X—R1—C(═O)—O—H wherein compound (I) can be polymerized to provide a polymer that contains therapeuticall... | 08/12/2008 |
| 7371895 | Salt forms of poorly soluble probucol esters and ethers Organic amine salts of compounds of the formula: and their pharmaceutically acceptable salts, and uses in medical therapy are provided. ... | 05/13/2008 |
| 7365223 | Method for selective targeting of apoptotic cells and small molecule ligands used thereof The invention provides novel methods for selective targeting of chemical compounds to cells undergoing a death process, in particular apoptosis, and to platelets undergoing activation during blood coagulation. The invention further provides compounds to be used in s... | 04/29/2008 |
| 7319163 | Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac arrhythmias, thyrotoxicosis and subclinical hyperthyrodism. ... | 01/15/2008 |
| 7316996 | Bisacyloxypropylcysteine conjugates and the use thereof The invention provides lipopeptide conjugates in which a cysteine that is double-substituted by a fatty acid is bonded by means of the carboxyl group to a highly soluble, physiologically compatible and non-immunogenic, polymeric conjugate group. The conjugates exhib... | 01/08/2008 |
| 7314888 | Compounds and medicinal use thereof A compound or a salt thereof having the atom corresponding to N3 and the two or more atoms selected from N1, N2, N4 and N5, said atoms constitute the pharmacophore represented by the following formula: | 01/01/2008 |
| 7301050 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia. ... | 11/27/2007 |
| RE39916 | Compounds that modulate PPAR activity and methods for their preparation This invention discloses compounds that alter PPAR activity. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds of their salts, and methods of using them as therapeutic a... | 11/06/2007 |
| 7273948 | Process of preparing esters and ethers of probucol and derivatives thereof A probucol or a probucol derivative can be efficiently converted to a monoester or monoether of probucol by reacting the free hydroxyl-containing probucol or a derivative thereof (by which is meant a probucol compound with at least one substituent that is different ... | 09/25/2007 |
| 7259276 | Polyenecarboxylic acid derivatives, processes for preparing them, and their use The present invention relates to novel compounds, termed serpentemycins, of the formula (I) in which Y, R, R2, R3, R4, X, X2, X3, n, m and o are as defined i... | 08/21/2007 |
| 7232845 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 06/19/2007 |
| 7230063 | Functional trithiocarbonate RAFT agents The present invention is directed to a free radical control agent of the structural formula: wherein R1 is a divalent alkyl group of 1 to 12 carbon atoms, R2 and R3 are each indep... | 06/12/2007 |
| 7220880 | Amide linker peroxisome proliferator activated receptor modulators The present invention is directed to compounds, compositions, and use of compounds the structural Formula (I) ... | 05/22/2007 |
| 7211625 | Thermoplastic resin composition and elastomer composition Provided are a thermoplastic resin composition which is excellent in oil resistance, heat resistance, weatherability, impact resistance, transparency, and moldability, and which can be produced economically, an elastomer composition with low hardness and high tensil... | 05/01/2007 |
| 7205435 | Type B botulism toxin inhibitors Novel compounds of general formula (I), are provided with inhibitory properties for the type B botulism toxin activity, along with methods for preparation thereof and corresponding pharmaceutical compositions. ... | 04/17/2007 |
| 7205368 | S-(α, α′-disubstituted-α′ ′-acetic acid) substituted dithiocarbonate derivatives for controlled radical polymerizations, process and polymers made therefrom Dithiocarbonate derivatives are disclosed, along with a process for preparing the same. The dithiocarbonate compounds can be utilized as initators, chain transfer agents and/or terminators in controlled free radical polymerizations. The dithiocarbonates can be used ... | 04/17/2007 |
| 7199265 | Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of m... | 04/03/2007 |
| 7183317 | Compounds and methods to increase plasma HDL cholesterol levels and improve HDL functionality It has been discovered that certain selected ethers of probucol, and their pharmaceutically acceptable salts or prodrugs, are useful for increasing circulating HDL cholesterol. These compounds may also improve HDL functionality by (a) increasing clearance of cholest... | 02/27/2007 |
| 7183298 | Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors This invention pertains to certain active carbamic acid compounds which inhibit HDAC activity and which have the following formula: (I) A is an aryl group; Q1 is a covalent bond or an aryl leader group; J is a sulfonamide linkage selected from: —S(═O)... | 02/27/2007 |
| 7153993 | Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid Process for making a pharmaceutical composition, comprising: a compound of formula (1) in crystalline form: together with a pharmaceutically acceptable carrier or excipient, whe... | 12/26/2006 |
| 7148473 | Time of flight mass spectrometer In a time of flight mass spectrometer (TOF-MS) of the present invention, a flight controller makes ions fly a loop orbit a predetermined number of turns, and an ion detector detects the ions at each turn of the flight. A flight time measurer measures the length of f... | 12/12/2006 |
| 7129374 | Catalytic antioxidants and methods of use The invention provides small molecules that act as catalytic antioxidants and methods of use thereof. The compounds can repeatedly bind and destroy reactive oxygen species by serving as substates for enzymes of the methionine sulfoxide reductase (Msr) class. Some em... | 10/31/2006 |
| 7125907 | Thiolactones This invention provides new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, inhibiting angiogen... | 10/24/2006 |
| 7091233 | Active substance combinations comprising insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 08/15/2006 |
| 7087645 | Compounds and methods for treating transplant rejection The use of compounds of the formula and pharmaceutically acceptable salts thereof, alone or in combination for the treatment of transplant rejection, wherein the substituents are further defined in the applicatio... | 08/08/2006 |
| 7037914 | Carboxylic acid derivative and a pharmaceutical composition containing the derivative as active ingredient A peroxisome proliferator activated receptor regulator containing a carboxylic acid derivative of formula (I) (wherein all symbols are as defined in the specification), a non-toxic acid thereof or a hydrate thereof as ... | 05/02/2006 |
| 7030133 | Inhibitors of formation of advanced glycation endproducts (AGEs) The nonenzymatic glycation and crosslinking of proteins is a part of the aging process with the glycation endproducts and crosslinking of long-lived proteins increasing with age. This process is increased at elevated concentrations of reducing sugars in the blood an... | 04/18/2006 |
| 7022875 | Thiobutacin and antifungal and antioomycete composition for controlling plant diseases using the same A novel antibiotic thiobutacin, obtainable from Lechevalieria aerocolonigenes strain VK-A9, and antifungal and antioomycete compositions comprising thiobutacin as an active ingredient for control of plant diseases, e.g., those attributable to pathogens such a... | 04/04/2006 |
| 6994866 | Combinations of active ingredients, which exhibit insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in... | 02/07/2006 |
| 6992215 | Thiol-based NAALADase inhibitors This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neurona... | 01/31/2006 |
