Quotables
"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7589230 | Process for the preparation of diphenic acid The present invention provides a process for the preparation of diphenic acid from phenanthrene which comprises heating phenanthrene and glacial acetic acid, adding drop-wise a pre-determined amount of 30% hydrogen peroxide, heating the resulting mixture after compl... | 09/15/2009 |
| 7393973 | Polycarboxylic acid production system with enhanced residence time distribution for oxidative digestion Disclosed is an optimized system for more efficiently and economically producing terephthalic acid. The system includes an oxidative digestion reactor/zone configured to provide optimized residence time distribution for the solid and liquid phases of the reaction me... | 07/01/2008 |
| 7271286 | Carboxylation of aromatic hydrocarbons to produce aromatic carboxylic acids Aromatic carboxylic acids are produced by reacting a Lewis acid: CO2 complex with aromatic hydrocarbons. The complex can be created by incubating a Strong Lewis acid and CO2 and forming a composition consisting essentially of CO2, st... | 09/18/2007 |
| 7262323 | Method for producing high purity terephthalic acid A method for producing high purity terephthalic acid wherein a slurry having an acetic acid solvent and, dispersed therein, crude terephthalic acid crystals which has been prepared by subjecting a p-alkyl benzene to a liquid phase oxidation in a solvent of acetic ac... | 08/28/2007 |
| 7126026 | Process for preparing 4-pentafluorosulfanylbenzoylguanidines A process for preparing 4-pentafluorosulfanylbenzoylguanidines of formula I wherein R1 to R4 have the meanings indicated in the specification. The compounds of formula I are NHE1 inhibitors and can be employed, f... | 10/24/2006 |
| 6958407 | Process for producing phenyl ester, and catalyst A phenyl ester is produced by allowing benzene, a carboxylic acid and molecular oxygen to react with each other in the presence of a catalyst comprising (A) palladium, (B) at least one element selected from elements of groups 13, 14, 15, and 16 and the fourth to six... | 10/25/2005 |
| 6870067 | Process for the synthesis of trifluorophenylacetic acids The present invention is concerned with a process for the preparation of trifluorophenylacetic acids using a Grignard reagent and an allylating agent, such as allyl bromide. ... | 03/22/2005 |
| 6852893 | Method for oxidizing hydrocarbons The invention relates to a method for oxidizing substrates such as hydrocarbons, waxes or soot. The method involves the use of a compound of formula (I) in which: R1 and R2 represent H, an aliphatic or aromatic alkoxy radical, carboxyl radical, alkoxycarbonyl radica... | 02/08/2005 |
| 6765113 | Production of aromatic carboxylic acids A process for the production of an aromatic carboxylic acid comprising contacting in the presence of a catalyst, within a continuous flow reactor, one or more precursors of the aromatic carboxylic acid with an oxidant, such contact being effected with said precursor... | 07/20/2004 |
| 6660883 | Process for the preparation of 2-aryl propionic acids The present invention provides an improved process for the preparation of 2-aryl propionic acid which by subjecting an aryl compound selected from an aryl alcohol or aryl halide or an aryl olefin to carbonylation in the presence of a halide source, a prot... | 12/09/2003 |
| 6548698 | Oxidative carbonylation of toluene catalyzed by rhodium and iridium This invention relates generally to the oxidative carbonylation of toluene, catalyzed by rhodium or iridium complexes in the presence of an oxidant and under mild conditions, whereby toluic acid is produced with para-selectivity up to 98%.... | 04/15/2003 |
| 6518455 | Process for preparing substituted aromatic and heteroaromatic aldehydes and carboxylic acids A process for preparing substituted aromatic and heteroaromatic aldehydes or carboxylic acids of the formula ##STR1## in which R1 and R2 are H, C1 -C4 alkyl, C1 -C4 alkoxy, OH, NO2 | 02/11/2003 |
| 6458994 | Process for producing aromatic polycarboxylic acid A process for producing a polycarboxylic acid which comprises performing liquid phase oxidation of polyalkyl-substituted aromatic aldehyde and/or oxide derivative of polyalkyl-substituted aromatic aldehyde as raw material for oxidation with molecular oxyg... | 10/01/2002 |
| 6448412 | Methods for the preparation and characterization of multi-substituted fullerenes The invention is directed to multiply-substituted fullerene derivatives of novel configurations, and methods for their preparation and use. The methods involve the combinatorial synthesis of a library of fullerene derivatives and comprises the steps of fo... | 09/10/2002 |
| 6429203 | Farnesyl-protein transferase inhibitors Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described... | 08/06/2002 |
| 6384279 | Synthesis of a tetraamido macrocycle ligand from a novel diamidodiol A new composition of matter for a diamidodiol and a method for preparing the diamidodiol. The exemplary diamidodiol has the formula C15 H30 N2 O4 and is prepared by reacting a first quantity of 2-amino-2-methyl-... | 05/07/2002 |
| 6342620 | Process for producing phenyl ester A phenyl carboxylate is produced by allowing benzene, a carboxylic acid and molecular oxygen to react with each other in the coexistence of a palladium catalyst with at least one additive selected from alcohols, aldehydes, cyclic hydrocarbons and formic a... | 01/29/2002 |
| 6288270 | Methods for controlling the reaction rate of a hydrocarbon to an acid by making phase-related adjustments Methods for controlling the reaction rate of a hydrocarbon to an acid by making phase-related adjustments are disclosed. In order to improve reaction rate of the oxidation, a single phase at the operating temperature is attained and maintained by adjustin... | 09/11/2001 |
| 6169201 | Process for the preparation of N-acylamino acids Process for the preparation of N-acetyl protected amino acids of Formula I ##STR1## by amido carbonylation utilizing carbon monoxide, nitrile, and an aldehyde in the presence of a metal catalyst.... | 01/02/2001 |
| 6100427 | Production of amides and/or acids from nitriles A process for producing an amide and/or acid from a nitrile comprises introducing a nitrile, as a first reactant, and a hydration compound, as a second reactant which is capable of reacting with the nitrile to convert it to its corresponding amide thus hy... | 08/08/2000 |
| 6051565 | Farnesyl-protein transferase inhibitors Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described... | 04/18/2000 |
| 5811588 | Process for the preparation of 3-phenylpropanal Process for the preparation of 3-phenylpropanal in which cinnamaldehyde is hydrogenated with the aid of a Pd-containing catalyst in the presence of a small amount of water. A high yield and a high selectivity are obtained in a commercially attractive proc... | 09/22/1998 |
| 5756858 | Process for the preparation of substituted phenylacetic acid derivatives and novel intermediates The invention relates to novel processes for the preparation of phenyl acetic acid derivatives of the formula (I) some of which are known ##STR1## in which R1, R2 and R3 independently of each other each represent hydr... | 05/26/1998 |
| 5731460 | Oxidative cleavage of alkenes with a catalyst system containing a source of molybdenum, a source of rutlenium and a phase transfer agent A catalyst system and process for the oxidative cleavage of alkenes with hydrogen peroxide is provided. The catalyst system comprises a source of ruthenium, a source of molybdenum and a phase transfer agent. The process comprises contacting an alkene with... | 03/24/1998 |
| 5686638 | Process for the preparation of mono- or dicarboxylic acids from aldehydes, from their full acetals or hemiacetals or from mixtures thereof Process for the preparation of aliphatic or aromatic mono- or dicarboxylic acids of 4 to 22 carbon atoms by oxidation of the corresponding aldehydes having the same number of carbon atoms in a carboxylic acid from the group consisting of formic acid, acet... | 11/11/1997 |
| 5616734 | Process for the catalytic oxidation of aromatic compounds The invention relates to the use of compounds of the formula I R1a Reb Oc (I), where a is from 1 to 6, b is from 1 to 4 and c is from 1 to 14 and the sum of a, b and c is in accordance with the... | 04/01/1997 |
| 5523472 | Process for the preparation of 5-fluoroanthranilic acid The present invention relates to a process for the preparation of 5-fluoroanthranilic acid, which comprises reacting 5-fluoro-2-bromotoluene in the presence of a catalyst and of an acidic solvent, with oxygen or an oxygen-containing gas at from 80° to 22... | 06/04/1996 |
| 5278321 | Process for simultaneously producing lactone and aromatic carboxylic acid A process for simultaneously producing a lactone and an aromatic carboxylic acid, which comprises oxidizing a cyclic ketone and an aromatic aldehyde wherein: the cyclic ketone/aromatic aldehyde molar ratio is set at 1.1:1 to 20:1 and the throughput of the... | 01/11/1994 |
| 4959494 | Oxidation of organic compounds with pyrochlore catalysts A method for oxidizing organic compounds by contacting organic compounds with molecular oxygen in the presence of a noble metal pyrochlore having the formula: A2+x B2-x O7-y wherein A is a pyrochlore structure metal cation, and... | 09/25/1990 |
| 4940808 | Process for ozonization of unsaturated organic compounds A process for the ozonization of unsaturated organic compounds in a reaction column through which the unsaturated compounds--in solution in a protic solvent--and an ozone-containing carrier gas and an inert coolant are passed downward in co-current flow t... | 07/10/1990 |
| 4883910 | Oxidation of organics by a vanadium containing heteropolyanion compound An organic compound having a cyclic aliphatic moiety is oxidized with a vanadium containing heteropolyanion compound having the formula Am XY12-n Vn+5 O40 wherein A is H, Li, K or Na: X is P+5, Si | 11/28/1989 |
| 4880894 | Quaternary ammonium salts used as phase transfer catalyst Novel quaternary ammonium salts of general formula (I) ##STR1## wherein: R is a saturated or unsaturated, linear or branched alkyl radical of C1 to C8. R' is a saturated or unsaturated, linear or branched alkyl radical of C... | 11/14/1989 |
| 4831189 | Process for producing aromatic dicarboxylic acids A process for producing an aromatic dicarboxylic acid which comprises subjecting a "K-region" arene to liquid phase oxidation with hydrogen peroxide in a water-insoluble organic solvent in the presence of a tungsten compound and a phase transfer catalyst ... | 05/16/1989 |
| 4709088 | Process for producing 2,6-naphthalene-dicarboxylic acid A process for producing 2,6-naphthalenedicarboxylic acid which comprises oxidizing 2,6-diisopropylnaphthalene or its oxidation product as a starting material with molecular oxygen in a reaction medium containing at least 50% by weight of an aliphatic mono... | 11/24/1987 |
| 4477380 | Oxidation process of reactive aromatics with reactivation of the catalyst using potassium permanganate In the oxidation of reactive aromatics with molecular oxygen in carboxylic acid solution in the presence of a catalyst consisting of a cobalt compound and possibly with addition of a manganese and a bromine compound suitable as Co-catalyst, an inactivatio... | 10/16/1984 |
| 4465855 | Process for the preparation of arylacetic acid derivatives Arylacetic acid derivatives of the formula ##STR1## with R1, R2 and R3 specifically defined and which are useful as antirheumatic and antiinflammatory pharmaceuticals are prepared by catalytic hydrogenation of new com... | 08/14/1984 |
| 4395571 | Process for the preparation of d,1-2-(6-methoxy-2-naphthyl)propionic acid Racemic mixtures of d,1-2-(6-methoxy-2-naphthyl)propanal are resolved by forming a condensation product with N-R-D-glucamine or a salt thereof where R is hydrogen, alkyl of 1 to 36 carbon atoms or cycloalkyl of 3 to 8 carbon atoms, from which a product su... | 07/26/1983 |
| 4382146 | Organic acids and process for preparing same A mixture of polycyclic, aromatic polycarboxylic acids carrying nuclear nitro groups that is substantially soluble in an azeotropic mixture of methyl ethyl ketone and ethanol but substantially insoluble in water, and a process for preparing the mixture of... | 05/03/1983 |
| 4375553 | Process for producing benzene carboxylic acid salts from aromatic materials This invention relates to a method of producing an aqueous solution which comprises soluble benzene carboxylic acid salts which is substantially free of soluble humic acid salts. A first aqueous solution (22) which comprises soluble humic acid salts and s... | 03/01/1983 |
| 4368333 | Method for the chemical utilization of coal by liquid phase oxidation The invention relates to an improved method for the liquid phase oxidation of coal performed with oxygen optionally in the presence of water. According to the invention oxidation is performed in the presence of a cooxidation partner selected from the grou... | 01/11/1983 |
