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| Number | Title | Issue Date |
| 8129564 | Mitigating necrosis in transgenic glyphosate-tolerant cotton plants treated with herbicidal glyphosate formulations This invention relates generally to improved methods and herbicidal glyphosate compositions for use in controlling the growth of weeds and unwanted vegetation, and particularly for use in controlling weeds in a crop of transgenic glyphosate-tolerant cotton plants by... | 03/06/2012 |
| 7932419 | Transition metal-containing catalysts and processes for their preparation and use as oxidation and dehydrogenation catalysts This invention relates to the field of heterogeneous catalysis, and more particularly to catalysts including carbon supports having formed thereon compositions which comprise a transition metal in combination with nitrogen and/or carbon. The invention further relate... | 04/26/2011 |
| 7683207 | Purification of n-(phosphonomethyl)glycine The present invention is a process for the purification of glyphosate (PMG) comprising: 1) dissolving or suspending a material comprising PMG in water, in the presence of a base, to produce a composition comprising a PMG salt in an... | 03/23/2010 |
| 7402576 | Phosphinic acid analogs of glutamate Inhibitors of axillary malodour having the formula wherein R has the same meaning as given in the specification. ... | 07/22/2008 |
| 7319095 | Use of GABAreceptor agonists The present invention relates to the use of GABAB receptor agonists for the treatment as well as the prevention of cough. ... | 01/15/2008 |
| 7186705 | Process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives The present invention relates to a process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives of the formula I, which are valuable pharmaceutical active ingredients and can be used, for exa... | 03/06/2007 |
| 7053138 | Flame-proofing agents Compounds of formula (I) or (II), wherein R1 is C1–C18alkyl; C5–C12cycloalkyl that is unsubstituted or substituted by one or more C1–C6alkyl groups or C1–C6alk... | 05/30/2006 |
| 7034176 | Aminopropylphosphinic acids Intermediates used in the preparation of compounds of formula I, or a stereoisomer thereof, or a pharmaceutically acceptable form of either selected from the group consisting of a salt, a solvate and a combination there... | 04/25/2006 |
| 7009071 | Process for the preparation of 4-amino-1-hydroxybutylidene-1, 1-biphosphonic acid This invention is related with the preparation of 4-amino-1-hydroxybutylidene-1,1-biphosphonic acid or salts thereof. The reaction of 4-aminobutyric acid with phosphorous acid and phosphorus trichloride in the presence of aralkyl or alkyl ethoxylates or triglyceride... | 03/07/2006 |
| 7005533 | Bisphosphonate derivatives, their preparations and uses The present invention relates to derivatives of 1-hydroxymethylene-1,1-bisphosphonic acid, the pharmaceutical compositions comprising them, and their application in therapeutics, particularly for the treatment of cancerous tumors. It is also directed to a methods of... | 02/28/2006 |
| 6962907 | Neurologically-active compounds The invention provides compounds of the formula II: wherein R represents propyl, butyl, pentyl, neo-pentyl or cyclohexyl, and salts thereof. These compounds are selective GABAC receptor antagonists. The inve... | 11/08/2005 |
| 6963008 | Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturing them, ar... | 11/08/2005 |
| 6919322 | Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors Novel FBPase inhibitors of the formula I are useful in the treatment of diabetes and other conditions associated with elevated blood glucose. ... | 07/19/2005 |
| 6867326 | Method of producing glyphosate or a salt thereof In a process for preparing N-phosphonomethylglycine or a salt thereof by bringing phosphonomethyliminodiacetic acid or a salt thereof into contact with at least one oxygen-containing oxidant in the presence of a heterogeneous catalyst, the heterogeneous catalyst com... | 03/15/2005 |
| 6852878 | Thioketals and thioethers for inhibiting the expression of VCAM-1 Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders,... | 02/08/2005 |
| 6841698 | Aminopropylphosphinic acids Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S,3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more G... | 01/11/2005 |
| 6793825 | Process for the separation of organic substances from an aqueous mixture The present invention relates to a process for separating from an aqueous mixture one or more organic substances containing at least one positively charged and/or chargeable nitrogenous group by means of extraction via at least one porous membrane, wherein use is ma... | 09/21/2004 |
| 6753324 | Phosphorous organic compounds and their use Use of phosphorous organic compounds of general formula (I) wherein B represents either an ether group of the formula (II) or a keto group of the formula (III) | 06/22/2004 |
| 6696602 | Method for the production of phosphonomethylglycine The present invention relates to a process for the preparation of phosphonomethylglycine, wherein N-phosphonomethyliminodiacetic acid N-oxide is brought into contact with a catalytically effective amount of thiocyanic acid or a salt thereof.... | 02/24/2004 |
| 6683209 | Aromatic imide and aromatic methylidynetrissulfonyl compounds and method of making A method is provided for making aromatic-imide and aromatic-methylidynetrissulfonyl species by reaction of aromatic species with a reactant according to formula (I): wherein Q is C or N; wherein each X is independently selected from the group consisting o... | 01/27/2004 |
| 6610743 | Bicyclic metabotropic glutamate receptor ligands The present invention provides bicyclic metabotropic glutamate receptor ligands, as well as compositions comprising such ligands, and and methods for their use.... | 08/26/2003 |
| 6596711 | (Aminopropyl)methylphosphinic acids Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)methylphosphinic acid; ii) (S)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iii) (R)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iv) (3-amino-2-hydroxypropyl)difluorom... | 07/22/2003 |
| 6590118 | Aromatic compounds Disclosed are compounds of formula I ##STR1## wherein A, R1, R2, R3, R4 and R5 are described in the specification, pharmaceutical formulations comprising these compounds, the use of these compounds are medicaments, the use of these medicaments in the trea... | 07/08/2003 |
| 6583126 | Phosphonic acid derivatives as inhibitors of protein tyrosine phosphatase 1B (PTP-1B) The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme. ##STR1## The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases, ... | 06/24/2003 |
| 6576626 | Aminopropylphosphinic acids Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)phosphinic acid; and ii) (2R/S, 3R)-(3-amino-2-hydroxybutyl)phosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable... | 06/10/2003 |
| 6521769 | Chiral phosphines, transition metal complexes thereof and uses thereof in asymmetric reactions Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are disclosed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corresponding alcohols... | 02/18/2003 |
| 6509324 | Chelating compounds, their complexes with paramagnetic metals Compounds able to chelate bi- and trivalent paramagnetic metal ions, their chelated complexes with these metal ions and physiologically compatible salts thereof and therein magnetic resonance imaging.... | 01/21/2003 |
| 6506934 | Water soluble halogen-containing compounds This invention relates to a compound that is represented by the following Structure I: R1 --SO2 --C(R2)R3 --(CO)m --(L)n --SG I wherein R1 is an aliphatic or cyclic group, R2 a... | 01/14/2003 |
| 6451761 | N'N'-dichlorinated omega-amino acids and uses thereof A method of treating a CNS disorder in a subject in need of such treatment, the method comprising administering to the subject an effective amount of an N'N'-dichlorinated amino acid, peptide, peptidomimetic, amine, or a pharmacologically acceptable analo... | 09/17/2002 |
| 6403826 | Corrosion-inhibiting coating composition for metals A description is given of compounds of the formula ##STR1## in which the general symbols are as defined in claim 1, and of their zirconium, bismuth and calcium salts, and of the salts with the compounds of the formula II ##STR2## in which the general... | 06/11/2002 |
| 6395930 | Quenching reagents for solution phase synthesis A method for enhancing the purity of a desired compound comprising: Step (a) treating a crude reaction product which contains at least one desired compound, unreacted starting materials and/or byproducts with at least one bifunctional quenching agent that is c... | 05/28/2002 |
| 6359162 | Method for producing glufosinates and intermediate products for the same Glufosinate and the 2-methyl analog thereof can be prepared in a multi-step synthesis from methylphosphorus compounds (II) with unsaturated keto compounds (III) via adducts (IV), subsequent reaction under the conditions of a Strecker synthesis and finally... | 03/19/2002 |
| 6329547 | Vinylbenzene derivatives The present invention provides compounds represented by the following general formula [I] and salts thereof, which are useful as therapeutic agents for glaucoma, ##STR1## wherein R1 is H, lower alkyl or phenyl, and the phenyl can be substi... | 12/11/2001 |
| 6291702 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 09/18/2001 |
| 6284914 | Highly water-soluble metalloproteinase inhibitors New compounds of general formulae (III), (IV) and (V). ##STR1##... | 09/04/2001 |
| 6281381 | Hydrate forms of alendronate sodium, processes for manufacture thereof, and pharmaceutical compositions thereof New hydrate forms of alendronate sodium, having water content of between about one and about twelve percent, and processes for their manufacture, are disclosed. New crystalline forms of alendronate sodium B, D, E, F, G and H, and processes for manufacturi... | 08/28/2001 |
| 6201148 | Process for preparing alendronic acid A novel process for the preparation of alendronic acid is disclosed. The method comprises the steps of reacting a compound of formula I with H3 PO3 ##STR1## wherein R is an imido group and R1 is selected from the group ... | 03/13/2001 |
| 6197825 | Azulenyl nitrone spin trapping agents, methods of making and using same The present invention relates to chromotropic nitrone spin trapping agents, methods of making these agents, compositions comprising same, and methods of their use. In particular, azulenyl nitrones of the present invention are effective agents for trapping... | 03/06/2001 |
| 6174874 | Phosphonic acids derivatives as inhibitors of protein tyrosine phosphate 1B (PTP-1B) The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme. ##STR1## The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases.... | 01/16/2001 |
| 6160164 | Corrosion-inhibiting coating composition for metals A description is given of compounds of the formula ##STR1## in which the general symbols are as defined in claim 1, and of their zirconium, bismuth and calcium salts, and of the salts with the compounds of the formula II ##STR2## in which t... | 12/12/2000 |
