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| Number | Title | Issue Date |
| 8017797 | Method for producing phosphorus-containing α-keto acid A method for efficiently producing 4-(hydroxymethylphosphinyl)-2-oxobutanoic acid, useful as a production intermediate of herbicide L-AMPB. The method comprises using a compound represented by the below formula (4): (4) where R1 represents a C1-4 | 09/13/2011 |
| 7705177 | Ketone compounds and compositions for cholesterol management and related uses The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a com... | 04/27/2010 |
| 7687657 | Process for preparing acylphosphanes and derivatives thereof The invention relates to a process for the preparation of (bis)acylphosphanes of formula I, wherein n and m are each independently of the other 1 or 2; R1 if n=1, is e.g. unsubstituted or substituted C1-C18alkyl or C2-C18a... | 03/30/2010 |
| 7429669 | Therapeutic compounds Disclosed herein are compounds of the formula or salts or bioisosteres thereof. Therapeutic methods, medicaments, and compositions related thereto are also disclosed. ... | 09/30/2008 |
| 7414157 | Hydroxylation of β-dicarbonyls with zirconium catalysts The present invention pertains to a process for preparing a compound of Formula I that is achiral, racemic or enantiomerically enriched at the hydroxylation center indicated by comprising contacting a compound of Formula II with an oxidant selected from oxygen, hydr... | 08/19/2008 |
| 7411084 | Method of preparing phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof via a dicarboxylate intermediate The present invention relates to a method of preparing a phenoxy alkanoic, alkenoic, or alkynoic acid or a salt thereof from a phenoxy containing compound via a dicarboxylate intermediate. The phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof prepared... | 08/12/2008 |
| 7317100 | Epothilone derivatives The present invention relates to C4-demethyl-epothilones or C4-bisnor-epothilones of Formula (I), their pharmaceutical use, pharmaceutical composition containing the same and methods for their preparation. ... | 01/08/2008 |
| 7208630 | Heat shock protein 90 inhibitors Novel compounds useful for inhibiting the 90 kDa heat shock proteins containing a quinone-like moiety and a di-hydroxy phenol like moiety, similar to geldanamycin and radicicol. ... | 04/24/2007 |
| 7166750 | Process for the preparation of 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone 5-[(4-chlorophenyl)methyl]-2,2-dimethylcyclopentanone is produced by reacting 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic acid methyl ester or 1-[(4-chlorophenyl)methyl]-3-methyl-2-oxocyclopentanecarboxylic acid... | 01/23/2007 |
| 7166648 | Photoinitiator, novel compound, and photocurable composition A photoinitiator is provided which exhibits excellent photosensitivity, yields colorless products, and is usable in thick layer UV curable coating. A novel chemical compound is also provided which is usable for the photoinitator. Photocurable composition is also pro... | 01/23/2007 |
| 7163956 | Substituted fullerene compositions and their use as antioxidants This patent discloses a substituted fullerenes, compositions comprising the same, and their use as antioxidants. The substituted fullerenes comprise a fullerene core (Cn) and at least one of: (i) from 1 to 6 (>CX1X2) groups bonded to the fuller... | 01/16/2007 |
| 7163827 | Aromatic esters for marking or tagging organic products A compound represented by formula I is used as a marker for organic products. wherein Ar1 and Ar2 each independently represent a substituted or unsubstituted phenylene group or a substituted... | 01/16/2007 |
| 7160902 | Amide derivatives and methods of their use Amide derivatives of the general formulae Ia and Ib: are disclosed. Pharmaceutical compositions containing these compounds, and methods for their use, inter alia, for treating and/or preventing gastrointestinal d... | 01/09/2007 |
| 7161022 | Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting... | 01/09/2007 |
| 7148265 | Functional polymer A polymer having α,β unsaturated groups and a group that generates a free radical when exposed to actinic radiation. The polymer may be self-cross-linking. ... | 12/12/2006 |
| 7148227 | Fungicidal triazolopyrimidines, methods for producing the same, use thereof for combating harmful fungi and agents containing said substances The invention relates to triazolopyrimidines of formula (I), in which the substituents are defined as follows: L1 represents cyano, S(═O)nA1 or C(═O)A2, wherein A1 stands for hydrogen, hydroxy, alkyl, alkyla... | 12/12/2006 |
| 7141694 | Enzymatic resolution of aryl and thio-substituted acids Provided is a method of resolving a racemic mixture of a compound of formula I to obtain a desired enantiomer: wherein Ar is C6 or C10 aromatic group that can be substituted with H, C1 ... | 11/28/2006 |
| 7129367 | Phosphine compound, its intermediate, its complex with palladium and a manufacturing method of unsaturated compounds by using the palladium complex Palladum-phosphine complexes obtained by reacting a 5 compound of formula (1) below with a palladium compound: F(I) (wherein R1 is a hydrogen atom, an alkyl group, a cycloalkyl group or a phenyl group which may be substituted; R2 and R3 | 10/31/2006 |
| 7128888 | Proton conductor and method for manufacturing the same, and electrochemical device A proton conductor, a method for manufacturing the same, and an electrochemical device using the proton conductor are provided. The proton conductor includes a carbon derivative which has a carbon material selected from the group consisting of a fullerene molecule, ... | 10/31/2006 |
| 7109238 | Calcilytic compounds Novel calcilytic compounds and methods of using them are provided. ... | 09/19/2006 |
| 7098201 | Heteroaromatic derivatives having an inhibitory activity against HIV integrase A compound of the formula (I): wherein X is hydroxy, protected hydroxy or optionally substituted amino; Y is —COORA wherein RA is hydrogen or ester residue, —CONRBRC wher... | 08/29/2006 |
| 7094894 | Fungicidal triazolopyrimidines, method for the production thereof, use thereof for controlling harmful fungi, and agents containing said fungicidal triazolopyrimidines Disclosed are a method for producing fungicidal triazolopyrimidine compounds, agents containing said compounds, and the use thereof for controlling harmful fungi. Also disclosed are triazolopyrimidines of formula (I), in which the substituents have the following mea... | 08/22/2006 |
| 7090832 | Cooling agents, pharmaceutical compositions having cooling agents and processes for making and using same The invention pertains to cooling agents comprising N-substituted p-menthane-3-carboxamides, menthyl acetate and solubilizer, and methods for making the cooling agents. The invention also concerns pharmaceutical compositions comprising the cooling agents, including ... | 08/15/2006 |
| 7078556 | Antibiotics Cyan-416 A, Cyan-416 B, Cyan-416 C, Cyan-416 D and Cyan-416 E, and ester derivatives of Cyan-416 B The invention relates to new antibiotics designated Cyan-416A, Cyan 416B, Cyan-416C, Cyan-416D and Cyan-416E to their production by fermentation of Acremonium sp. NRRL 30631 to methods for recovery and concentration from the crude solutions, and to a process ... | 07/18/2006 |
| 7074826 | R-NSAID esters and their use The present invention concerns esters of R-enantiomers of a non-steroidal anti-inflammatory drug, which is substantially free from the S-enantiomer. The compounds of the invention may be used in treating a disease or illness in a mammal. To this end, a composition c... | 07/11/2006 |
| 7070810 | Use of buckysome or carbon nanotube for drug delivery Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layer... | 07/04/2006 |
| 7034051 | Fused bicyclic carboxamide derivatives and methods of their use Fused bicyclic carboxamide derivatives are disclosed. Pharmaceutical compositions containing the compounds and methods for their use are also disclosed. ... | 04/25/2006 |
| 7026030 | Optical information medium The present invention provides an optical information medium in which the recording and/or reproducing beam incident side surface displays excellent anti-staining properties and lubricity, as well as superior scratch resistance and abrasion resistance. An optical in... | 04/11/2006 |
| 7022880 | Piperidine derivatives and process for their production The present invention relates to substantially pure piperidine derivative compounds of the formulae: wherein R1 is hydrogen or hydroxy; | 04/04/2006 |
| 6943196 | NF-κB inhibitor comprising phenylmethyl benzoquinone as the active ingredient An NF-κB inhibitor having as an active ingredient a benzoquinone derivative represented by the general formula (1) wherein R1, R2, and R3 are each independently H, alkyl having 1 to 5 carbons, or alkoxy having 1 to 5 carbons; R... | 09/13/2005 |
| 6911521 | Polyhydroxyalkanoate that comprises unit having substituted or unsubstituted (phenylmethyl) sulfanyl structure in side chain thereof and process for producing the same A polyhydroxyalkanoate that comprises a unit represented by the following chemical formula (1): wherein R1 is a substituent of an aromatic ring selected from the group consisting of H, CH3, C2H | 06/28/2005 |
| 6906113 | Surface-active photoinitiators Compounds of formula Ia, Ib and Ic, (Ic), in which R, R1 and R2 are e.g. phenyl, naphthyl, anthracyl, phenanthryl or a heterocyclic radical, are suitable as photoinitiators which accumulate at the surface of coatings. ... | 06/14/2005 |
| 6903232 | Process for the preparation of a highly pure pharmaceutical intermediate, 4-(cyclopropylcarbonyl)-α, α-dimethylphenylacetic acid This invention relates to a novel process to obtain highly pure 4-(cyclopropylcarbonyl)-α,α-dimethylphenylacetic acid of Formula I through crystallization from a mixture of para and meta regioisomers of Formula I and II in cyclohexane, whereby the amount of undesi... | 06/07/2005 |
| 6903230 | Process for producing a fluorine-containing compound It is to provide a process for synthesizing an intended fluorine-containing compound having a geminal difluoro structure with a high yield, by subjecting a carbonyl compound which is readily available to a two-stage reaction. A compound (1) such as ethyl 4-ox... | 06/07/2005 |
| 6890520 | Thermally stable ferulic acid derivatives A ferulic acid derivative represented by the general formula (1); a process for preparing a ferulic acid derivative represented by the general formula (1), comprising reacting ferulic acid or an ester thereof represented by the general formula (2) with a dihalometha... | 05/10/2005 |
| 6878718 | Phenylalanine enamide derivatives Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 | 04/12/2005 |
| 6858747 | Process to prepare, 1,4-dihydropyridine intermediates and derivatives thereof An improved catalyst is disclosed for a process involving the preparation of benzylidene intermediates useful in the preparation of 1,4-dihydropyridine compounds and derivatives thereof useful as medicines such as for example felodipine. This is accomplished by the ... | 02/22/2005 |
| 6855832 | O- or S-substituted tetrahydronaphthalene derivatives having retinoid and/or retinoid antagonist-like biological activity Compounds of the formula where the symbols have the meaning described in the application, have retinoid-like or retinoid antagonist-like biological activity. ... | 02/15/2005 |
| 6720445 | Acetyloxymethyl esters and methods for using the same Novel acetyloxymethyl esters are disclosed. Methods of treating an illness, including cancer, hemological disorders and inherited metabolic disorders, and treating or ameliorating other conditions using these compounds are also disclosed. The compounds are effective... | 04/13/2004 |
| 6703421 | Methods of using phenylmethylbenzoquinone and hydroquinone compounds for treatment of myocarditis, dilated cardiomyopathy and heart failure A method for prevention or treating myocarditis, dilated cardiomyopathy and heart failure comprising administering to a patient in need of such treatment a NF-.kappa.B inhibitor in a therapeutically effective amount, wherein said NF-.kappa.B inhibitor is ... | 03/09/2004 |
