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| Number | Title | Issue Date |
| 7619110 | Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof The present invention provides a prodrug of propofol and crystalline forms thereof, methods of making the propofol prodrug and crystalline forms thereof, pharmaceutical compositions of the propofol prodrug and crystalline forms thereof, methods of using the propofol... | 11/17/2009 |
| 7125991 | Compounds derived from benzoic acid esters, composition containing said compounds and use thereof The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 represents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 ... | 10/24/2006 |
| 6943191 | Disubstituted lavendustin A analogs and pharmaceutical composition comprising the analogs Disubstituted lavendustin A analogs that are PTK inhibitors having antiproliferative activity are described. Preferred compounds of the disclosure, without limitation, satisfy either Formula 1 or Formula 2. The present... | 09/13/2005 |
| 6930200 | Multicomponent synthesis of amino acids and derivatives thereof Mono-substituted and di-substituted alpha-amino acids and derivatives thereof, substituted at the alpha positon with one (mono-) or two (di-) substituents (R2 and/or R3) as shown in Formula 1: N(R4R5)C(R2R3... | 08/16/2005 |
| 6844003 | Compounds derived from benzoic acid esters, composition containing said compounds and use thereof The invention relates to novel compounds of formula (I) wherein R1 represents a polymer, aryl or alkyl group, R2 presents a hydrogen atom, a halogen atom, a radical CN, CF3, OH, OCF3, COOH, R7, OR7 or... | 01/18/2005 |
| 6600063 | Derivatives of phenyl 4-aminosalicylate and method of making the same The present invention relates to novel antimycobacterial compounds and in particular to antimycobacterial compounds comprised of derivatives of phenyl 4-aminosalicylate. This invention further relates to methods for their preparation, to their use as ther... | 07/29/2003 |
| 6552161 | Polarizable amines and polymides for optical alignment of liquid crystals The present invention relates to amine compositions and the preparation of polyimides. The polyimides can be used for inducing alignment of a liquid crystal medium with polarized light in liquid crystal display elements.... | 04/22/2003 |
| 6362369 | Phthalic acid diamide derivatives fluorine-containing aniline compounds as starting material, agricultural and horticultural insecticides, and a method for application of the insecticides The present invention provides a phthalic acid diamide derivative represented by the general formula (I) ##STR1## (wherein R1, R2 and R3 are each H, C3 -C6 cycloalkyl group, group of the formula --A | 03/26/2002 |
| 6358431 | Calixarenes A method of imparting a water repellent surface to a hydrophilic substrate which comprises contacting the substrate with a solution or dispersion of a suitable calixarene in a liquid medium.... | 03/19/2002 |
| 6137003 | Bis (haloethyl) aminobenzene derivatives The present invention relates to bis(haloethyl)aminobenzene derivatives featured by having carboxyl-containing moiety and one other moiety at the ortho position with respect to the bis(haloethyl)amino substituent of the benzene ring. The moiety at the ort... | 10/24/2000 |
| 6054457 | Benzamide derivatives and their use as vasopressin antagonists This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc, and represented by general formula (I): ##STR1## wherein R1 is aryl optionally substituted with lower alkoxy, etc., R2 is lower... | 04/25/2000 |
| 5969133 | Bioreductive cytotoxic agents A compound which consists of a proactive alkylating moiety containing an electron-withdrawing group, a bioreductive moiety containing at least two double bonds, and a linker joining the proactive alkylating moiety and the bioreductive moiety.... | 10/19/1999 |
| 5948922 | Compounds with substituted cyclic hydrocarbon moieties linked by secondary or tertiary oxycarbonyl containing moiety providing reworkable cured thermosets Compounds containing two cyclic hydrocarbon moieties which are substituted to provide crosslinking functionality and which are linked to each other by secondary or tertiary oxycarbonyl containing moiety are basis for compositions which are cured to provid... | 09/07/1999 |
| 5874608 | Process for the preparation of esters of aromatic carboxylic acid The present invention relates to a process for the preparation of compounds of the formula (1) R1 R2 R3 R4 R5 ArCOOR (1) in which R1, R2, R3, R4 and R | 02/23/1999 |
| 5717109 | Excitatory amino acid receptor antagonists The present invention provides compounds of formula ##STR1## in which R represents an organic group, or a pharmaceutically acceptable metabolically labile ester or amide thereof, or a pharmaceutically acceptable salt thereof, which are useful as anta... | 02/10/1998 |
| 5668156 | Di (aromatic) compounds and their use in human and veterinary medicine and in cosmetics Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## n=1 or 2 or: ##STR3## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2 | 09/16/1997 |
| 5599972 | Aminobenzoic acid derivatives An aminobenzoic acid derivative represented by the following general formulas (I), (I-2) or (I-3), or a pharmacologically acceptable salt thereof, which exhibits a serotonin antagonism and an acetylcholine release accelerating activity at a well-balanced ... | 02/04/1997 |
| 5476860 | Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics Diaromatic compounds, characterized in that they correspond to the following general formula: ##STR1## in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, -... | 12/19/1995 |
| 5387594 | Di(aromatic) compounds and their use in human and veterinary medicine and in cosmetics Di(aromatic) compounds corresponding to the following formula: ##STR1## in which: Ar represents either ##STR2## n=1 or 2 or: ##STR3## X represents a divalent radical, Z represents O, S or a divalent radical, and R1, R2... | 02/07/1995 |
| 5347036 | Substituted di-t-butylphenols Novel compounds which are 2,6-di-t-butylphenols substituted on the 4 position by an anilino group, which anilino group is substituted by a carboxyl substituent, a tetrazolyl substituent or an N-methyltetrazolyl substituent, are useful antiallergic agents.... | 09/13/1994 |
| 5331007 | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties There is provided a method of treatment of neurological disorders, such as epilepsy, stroke and cerebral ischaemia, which comprises the administration of a compound of Formula I: ##STR1## wherein, Ar1 and Ar2, which may be the s... | 07/19/1994 |
| 5314916 | B2 adrenegic agonists and use thereof in the treatment of glaucoma Compounds having beta-2 adrenergic agonist activity and the use of these compounds in controlling intraocular pressure are disclosed. The compounds are believed to be useful in controlling intraocular pressure by increasing the outflow of aqueous humor. T... | 05/24/1994 |
| 5247091 | Preparation of enamines in aqueous media The synthesis of enamines in aqueous media and a process for the preparation of memory enhancing 9-amino-1,2,3,4-tetrahydracridines are described.... | 09/21/1993 |
| 5208364 | Antibiotic 5-lipoxygenase inhibitors Novel compounds derived from cultures of Streptomyces sp. AA2807 are useful as 5-lipoxygenase inhibitors.... | 05/04/1993 |
| 5130454 | Polytetrahydrofuran derivatives having terminal aromatic groups Polytetrahydrofuran derivatives of the general formula ##STR1## where n is from 2 to 70, X is the bridge member --NH-- or --O-- and R1 and R4 are each hydrogen or various radicals.... | 07/14/1992 |
| 5106407 | Iodones and methods for antimicrobial use The present invention discloses the antimicrobial utility of certain iodonium ylide compounds. The particular iodonium ylide compounds are phenyl iodonium ylides having an ortho substituent that stabilizes the positive charge on the polyvalent iodine by a... | 04/21/1992 |
| 5068392 | Process for the preparation of 2-chloro and 2,6-dichloroanilines 2-Chloro and 2,6-dichloroanilines, optionally substituted in the 3-, 5-, and/or 6-position are prepared from the corresponding anilides by selective bromination, chlorination, reduction and hydrolysis. The selectivity of the process for introducing chlori... | 11/26/1991 |
| 5026912 | Alkylation of aromatic amines over thermally pretreated zeolites A process for selectively producing ortho-alkylated aromatic amines in high selectivity relative to N-alkylated aromatic amines. The process comprises reacting an aromatic amine, having at least one hydrogen atom in a position ortho to the amine functiona... | 06/25/1991 |
| 5025036 | Catechol carboxylic acids The invention relates to catechol carboxylic acid derivatives of the formula ##STR1## wherein, R1 is ##STR2## acetyl, hydrogen, hydroxy or alkanoyloxy, R2 is ##STR3## hydroxy, hydrogen or alkanoyloxy, wherein R ... | 06/18/1991 |
| 4999186 | Novel sunscreen agents, sunscreen compositions and methods for preventing sunburn The present invention relates to novel sunscreen agents which have the ability to absorb both UVA and UVB wavelength radiation. The sunscreen agents comprise a specific type of UVA-absorbing chromophore covalently bonded to a specific type of UVB-absorbin... | 03/12/1991 |
| 4983628 | Leukotriene antagonists Compounds having the formula: ##STR1## are antagonists of leukotrienes of C4, D4 and E4, the slow reaction substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory and c... | 01/08/1991 |
| 4978772 | Utilization of otilonium bromide (DCI) for topical application in the gastroinstestinal tract and related pharmaceutical formulation appropriate for such use Use of bromure d'otilonium, that it otilonii bromidum, for local applications in the gastrointestinal tract of the digestive system and related pharmaceutical formulation appropriate for such use, to obtain the arrest of the motility of the gastrointestin... | 12/18/1990 |
| 4908470 | Process for the methyl-4-(dimethylamino)-3,5-dimethoxybenzoate Methyl 4-dimethylamino-3,5-dimethoxybenzoate, an intermediate in the preparation of the antibacterially active aditoprim, is obtained from 4-amino-3,5-dibromobenzoic acid by replacement of the bromine atoms by methoxy groups and subsequent methylation.... | 03/13/1990 |
| 4894181 | Carbocyclic compounds Carbocyclic compounds of the formula I ##STR1## wherein Q is a benzene or cyclohexane ring or a naphthalene system, X is in each case --CH2 --(CH2)p -- where it is also possible for one or two non-adjacent CH2 | 01/16/1990 |
| 4869748 | Certain 3-(substituted benzoyl)-3:2:1-bicyclooctan-2,4-diones Herbicidal compounds of the formula ##STR1## wherein R is halogen; C1 -C2 alkyl; C1 -C2 alkoxy; trifluoromethoxy; difluoromethoxy; nitro; cyano; C1 -C2 haloalkyl; Ra SO... | 09/26/1989 |
| 4861799 | Benzoylurea compounds and pesticides containing them A benzoylurea compound having the formula: ##STR1## wherein each of X1 and X2 is a hydrogen atom, a halogen atom or a methyl group, provided that X1 and X2 are not simultaneously hydrogen atoms, Y is indepe... | 08/29/1989 |
| 4861796 | Gentisic acid derivatives having antibiotic activity 2-Acetylaminogentisic acid has been isolated from the culture broth after cultivation of a bacterium of the genus Streptomyces. This compound has antibacterial actions against Gram-positive and Gram-negative bacteria.... | 08/29/1989 |
| 4853398 | Leukotriene antagonists and use thereas This invention provides benzene derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.... | 08/01/1989 |
| 4826876 | Chemical compounds having selective thyromimetic activity This invention relates to chemical compounds which have selective thyromimetic activity. A compound of this invention is 3,5-dibromo-3'-[6-oxo-3(1H)-pyridazinyl-methyl]-thyronine.... | 05/02/1989 |
| 4808338 | Certain 3-oxo-4-(substituted oxy or substituted thio)cyclohex-1-enyl-2-substituted benzoate intermediates Intermediate compounds of the formula ##STR1## wherein X is oxy, thio, sulfinyl or sulfonyl; R is halogen; C1 C2 alkyl; C1 -C2 alkoxy; trifluoromethoxy; difluoromethoxy; nitro; cyano; C1 -C2... | 02/28/1989 |
