...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 8410301 | Methods for the synthesis of organic sulfides by using sulfides and organic sulfur-indium complexes The present invention relates to a novel synthesis method for the formation of carbon-sulfur bonds by the reaction of an organic sulfur-indium complex with nucleophile in the presence of a palladium catalyst. The present invention provides a synthesis method to prep... | 04/02/2013 |
| 7393873 | Arylsulfonamide derivatives N-aryl arylsulfonamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway. ... | 07/01/2008 |
| 7285686 | Process for the preparation of 1,3-substituted indenes An improved process for the preparation of 1,3 substituted indenes which are useful intermediates in the synthesis of aryl fused azapolycyclic compounds as agents for the treatment of neurological and psychological disorders. ... | 10/23/2007 |
| 7271196 | CETP activity inhibitors The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl group; a straight cha... | 09/18/2007 |
| 7250159 | Compositions comprising at least one ester of at least one hydroxylated aliphatic compound Compositions comprising at least one ester which comprises at least one aromatic group, which is liquid at room temperature and which is derived from esterification with (i) at least one aromatic acid of (ii) at least one hydroxyl group of at least one hydroxylated ... | 07/31/2007 |
| 7208510 | Fungicidal combinations of active substances The present invention relates to fungicidally active compound combinations of a fluorobenzothiazole derivative of the formula (I) and at least one of the compounds listed in the disclosure. ... | 04/24/2007 |
| 7205428 | Thioether derivatives, their method for production and use The present invention is directed to novel thioether dendritic molecules which respond immediately by emission of light when stimulated with light or electric energy. ... | 04/17/2007 |
| 7186870 | Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds The present invention relates to processes for the preparation of any of the intermediate 1,3-substituted indenes of the formulae (Ia), (Ib) and (Ic) or a mixture thereof: wherein R1, R2, R | 03/06/2007 |
| 7157458 | Bifunctional energy-reversible acyl-compositions Energy-reversible acyl conjugates, intermediates, and related compositions are disclosed. In preferred aspects, examples of such compositions include: ... | 01/02/2007 |
| 7115593 | Fungicidal combinations of active substances The present invention relates to active compound combinations of a fluorobenzo-thiazole of the formula (I) and at least one of the compounds listed herein. The active compound combinations of the present inventio... | 10/03/2006 |
| 7094919 | Preparation of substituted aromatic carboxylic acid esters Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester: Additionally the inventio... | 08/22/2006 |
| 7091372 | Process for the preparation of 1,3-substituted indenes and aryl-fused azapolycyclic compounds The present invention relates to processes for the preparation of any of the intermediate 1,3-substituted indenes of the formulae (Ia), (Ib) and (Ic) or a mixture thereof: wherein R1, R2, R | 08/15/2006 |
| 7078540 | Substituted aromatic-ring compounds, process for producing the same, and use A compound of the formula: wherein R1 is an aliphatic hydrocarbon group optionally having substituent(s), an aromatic hydrocarbon group optionally having substituent(s), a heterocyclic group optionally... | 07/18/2006 |
| 6860905 | Anionic phthalic acid ester compounds and stain resistant compositions This invention relates to compounds of formula: wherein A is an unsaturated alkylene moiety; B the residue of a polyol wherein one hydroxyl moiety is esterified with one carboxyl moiety of the phthalic acid moiety; D i... | 03/01/2005 |
| 6846890 | Norbornene derivative and norbornene polymer obtained therefrom through ring opening polymerization A novel norbornene derivative represented by a general formula (1m) shown below is provided. By conducting a ring opening polymerization of this norbornene derivative, or by performing a subsequent hydrogenation following the ring opening polymerization, a ring open... | 01/25/2005 |
| 6777575 | Process for the preparation of 2-alkylthio benzoic acid derivatives A process for preparing a compound of the formula comprising reacting a compound of the formula wherein R3 is nitro or halo, or a salt thereof, with a compound of ... | 08/17/2004 |
| 6649656 | Anthranilic acid derivatives The present invention relates to an anthranilic acid derivative expressed by the following formula (1) or the following formula (2), or its pharmacologically permissible salt or solvate. ##STR1##... | 11/18/2003 |
| 6638977 | Plasminogen activator inhibitor antagonists Compounds and pharmaceutical compositions useful as plasminogen activator inhibitor (PAI) antagonists are provided. In particular, methods of antagonizing PAI with substituted and unsubstituted aryl and heteroaryl ethers and thioethers are provided.... | 10/28/2003 |
| 6498265 | 3-amino-2-mercaptobenzoic acid derivatives and processes for their preparation Compounds of the formula I ##STR1## and disulfides thereof and salts thereof are important intermediate products for the preparation of compounds having a microbicidal and plant-immunizing action, of the formula III ##STR2## In the compounds of the f... | 12/24/2002 |
| 6495710 | Synthesis and use of dimethyl 1,5-naphthalenedicarboxlyates and intermediates therefrom The synthesis of dimethyl-1,5-naphthalenedicarboxylate and polymers and articles formed therefrom is disclosed, as well as applications for dimethyl-1,5-naphthalenedicarboxylate, its corresponding acid 1,5-NDA, and various synthesis intermediates.... | 12/17/2002 |
| 6479550 | -sulfenimino acid derivatives -Sulfenimino acid derivatives of formula I ##STR1## including the optical isomers thereof and mixtures of such isomers, wherein A is cycloalkyl, cycloalkenyl, aryl or heteroaryl, each optionally substituted, B is a direct bond or optionally substituted ... | 11/12/2002 |
| 6369261 | Compounds having activity as inhibitors of cytochrome P450RAI Compounds having Formula 2 wherein the symbols have the meaning defined in the specification are inhibitors of the cytochrome P450RAI (retinoic acid inducible) enzyme, and are used for treating diseases responsive to treatment by retinoids. ##STR1##... | 04/09/2002 |
| 6337418 | Preparation of C1-C5 alkyl esters of nitro or thioether substituted aromatic carboxylic acids Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester: ##STR1## Additionally the invention relates to a method for pr... | 01/08/2002 |
| 6337350 | Inhibitors of formation of advanced glycation endproducts (AGEs) Derivatives of aryl and heterocyclic ureido and aryl and heterocyclic carboxamido phenoxy isobutyric acids have been found to inhibit the nonenzymatic glycation of proteins which often results in formation of advanced glycation endproducts and crosslinks.... | 01/08/2002 |
| 6262293 | ω-Cycloalkly-prostaglandin e2 derivatives ω-Cycloalkyl-prostaglandin E2 derivatives of formula (I) ##STR1## (wherein all symbols are as defined in the description); and non-toxic salts thereof, prodrugs thereof and cyclodextrin clathrates thereof. Compounds of formula (I) strongly bind on ... | 07/17/2001 |
| 6187812 | Phenylacetic acid derivatives, preparation thereof and intermediates therefor, and compositions containing them Phenylacetic acid derivatives of the formula I ##STR1## where the substituents and the index have the following meanings: X is oxygen or sulfur; R is hydrogen or alkyl; R1 is hydrogen or alkyl; R2 is cyano, nitro, trifluoromethyl, halogen, alk... | 02/13/2001 |
| 6140528 | Intermediates to herbicidal isoxazole and 2-cyano-1,3-dione compounds The invention relates to intermediates to herbicidal compounds of formulae (Ia), (Ib) or (Ic): ##STR1##... | 10/31/2000 |
| 6072072 | Compounds for preparing modified hemoglobin The present invention provides a chemically modified form of hemoglobin that is stabilized and can efficiently bind and release oxygen. In addition the chemically modified hemoglobin may be polymerized to increase its molecular weight and increase its sta... | 06/06/2000 |
| 6054457 | Benzamide derivatives and their use as vasopressin antagonists This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc, and represented by general formula (I): ##STR1## wherein R1 is aryl optionally substituted with lower alkoxy, etc., R2 is lower... | 04/25/2000 |
| 6013606 | Substituted cinnamic oxime and hydroxamide derivatives Substituted cinnamic oxime derivatives I and cinnamic hydroxamide derivatives II ##STR1## (R1= halogen, NO2, CN, CF3 ; R2 =H, halogen; R3= H, halogen, C1 -C6 -alkyl, C1... | 01/11/2000 |
| 5981581 | Phenylacetic acid derivatives, preparation thereof and intermediates therefor, and compositions containing them Phenylacetic acid derivatives of the formula I ##STR1##... | 11/09/1999 |
| 5965524 | Analogs of viscosin and uses thereof This invention is directed to the analogs of viscosin, pharmaceutical compositions thereof and to methods of using viscosin and analogs thereof as biosurfactants and as antibacterial, antiviral and antitrypanosomal therapeutic compounds. In particular, co... | 10/12/1999 |
| 5962651 | Modified hemoglobin and its use as a component of an artificial blood substitute The present invention provides a chemically modified form of hemoglobin that is stabilized and can efficiently bind and release oxygen. In addition the chemically modified hemoglobin may be polymerized to increase its molecular weight and increase its sta... | 10/05/1999 |
| 5952386 | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen... | 09/14/1999 |
| 5945548 | Process for the synthesis of -substituted acrylic acids and their application Process for the synthesis of -substituted acrylic acids of general formula (I) and their application to the synthesis of N-(mercaptoacyl)aminoacid derivatives of formula (II). ##STR1##... | 08/31/1999 |
| 5877297 | Boronic compound complexing reagents and highly stable complexes Boron compound completing reagents, intermediate reagents of those reagents and methods of synthesizing these reagents. These reagents, including those shown as General Formula CII may be used, after further reactions described herein, to complex with bor... | 03/02/1999 |
| 5874608 | Process for the preparation of esters of aromatic carboxylic acid The present invention relates to a process for the preparation of compounds of the formula (1) R1 R2 R3 R4 R5 ArCOOR (1) in which R1, R2, R3, R4 and R | 02/23/1999 |
| 5869623 | Boronic compound complexing reagents and complexes Boron compound complexing reagents, intermediate reagents of those reagents, and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula II may be used, after further reactions described herein, to co... | 02/09/1999 |
| 5847192 | Boronic compound complexing reagents and complexes Boron compound complexing reagents and methods of synthesizing these reagents are disclosed. These reagents, including those shown as General Formula I and General Formula II may be used, after further reactions described herein, to complex with boronic c... | 12/08/1998 |
| 5831102 | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes Enzymatically cleavable chemiluminescent 1,2-dioxetane compounds capable of producing light energy when decomposed, substantially stable at room temperature before a bond by which an enzymatically cleavable labile substituent thereof is intentionally clea... | 11/03/1998 |