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| Number | Title | Issue Date |
| 7714162 | Base multiplying agents and base-reactive curable compositions To provide such a base multiplying agent capable of being used for crosslinking reaction, for example of a epoxy compound and the like, that generates another base by action of a base, and can efficiently perform base multiplying reaction, and a base-reactive curabl... | 05/11/2010 |
| 7414145 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active α-hydroxy-γ-keto acid ester and hydroxydiketone A method of an enantioselective nucleophilic addition reaction to carbonyl, which enables an asymmetric synthesis of an optically active α-hydroxy-γ-keto acid ester, an optically active α-hydroxy-γ-amino acid ester, hydroxydiketone compounds, etc. being useful a... | 08/19/2008 |
| 7166590 | Amino acid derivatives A compound of the formula (I): [wherein R1 is (substituted) alkyl, alkoxy, phenyl, hetero ring etc.; A is bond, CO, SO2; R2 is H, (substituted) alkyl etc.; D is alkylene etc.; E is COO,... | 01/23/2007 |
| 6960588 | Tryptase inhibitors Compounds of formula (I) in which M, B1, B2, B3, B4, B5, B6, A1, A2, A3, A4, A5, A6, K1 and K2 have the meanings as indicated in the description, are novel effective tryptase inhibitors. ... | 11/01/2005 |
| 6852738 | Acyl sulfamides for treatment of obesity, diabetes and lipid disorders A class of acyl sulfamides comprises compounds that are potent ligands for PPAR gamma and generally have antagonist or partial agonist activity. The compounds may be useful in the treatment, control or prevention of obesity, non-insulin dependent diabetes mellitus (... | 02/08/2005 |
| 6759511 | Compound used as an amino-protecting group, process for preparing the same, and synthetic method of a peptide using the same The present invention relates to a carbonic acid ester compound of the following formula (1): in which X, Y, and Ar are defined in the specification, which can be easily combined with the amino group of an amino acid or ... | 07/06/2004 |
| 6538024 | Felbamate derived compounds The present invention relates to novel felbamate derivatives and their use to treat neurological diseases such as epilepsy and to treat tissue damage resulting form ischemic events. The felbamate derivatives are modified to prevent the formation of metabo... | 03/25/2003 |
| 6384264 | Photoactive materials applicable to imaging systems Organic photoprecursors of amines are provided for use in photosensitive imaging systems, finding particular application in the preparation of lithographic printing plates. Said photoprecursors generate free amines on exposure to long wavelength UV or vis... | 05/07/2002 |
| 6372800 | Benzene compound and pharmaceutical use thereof A benzene compound of the formula ##STR1## wherein each symbol is as defined in the specification; an optically active isomer or salt thereof, a medicinal composition containing the same, and an immunosuppressant containing the same as the active ingredie... | 04/16/2002 |
| 6335459 | Aryl carboxylic acid and aryl tetrazole derivatives as IP receptor modulators This invention relates to compounds which are generally IP receptor modulators, particularly IP receptor agonists, and which are represented by Formula I: ##STR1## wherein R1, R2, R3, R4, R5, A, and B... | 01/01/2002 |
| 6140532 | O-carbamoyl-phenylalaninol having substituent at benzene ring, its pharmaceutically useful salts and method for preparing the same O-Carbamoyl-phenylalaninol having substituent at benzene ring, represented by the general formula I, and pharmaceutically useful salts thereof, which are useful for the prophylaxis and treatment of CNS disorder including depression and anxiety, are disclo... | 10/31/2000 |
| 6140531 | Method of preparing N-1-alkenyl carbonylamino compounds Describes a method of producing N-1-alkenyl carbonylamino compounds represented by the following general formula I, ##STR1## wherein R1 is the residue of an active hydrogen functional material, n is a number from 1 to a number equal to the... | 10/31/2000 |
| 6114325 | 1,2-di-substituted benzene-carboxamide derivative, hair growth promoter and external composition for skin using the same A 1,2-di-substituted benzene-carboxamide derivative or a salt thereof expressed by the following Formula (I); ##STR1## wherein each of A and B is R1 or --(CH2)n-NR2 R3, wherein when A is R1, B is... | 09/05/2000 |
| 6107499 | Dopamine analog amide The invention involves the formation of a prodrug from a fatty acid carrier and a neuroactive drug. The prodrug is stable in the environment of both the stomach and the bloodstream and may be delivered by ingestion. The prodrug passes readily through the ... | 08/22/2000 |
| 6004565 | Compositions and methods of using compositions with accelerated lymphocyte homing immunosuppressive properties The methods and compositions of the invention and the compounds used in the invention involve a novel immunosuppression mechanism, accelerated lymphocyte homing immunosuppression (ALH-immunosuppression). For example, the compound FTY720 specifically direc... | 12/21/1999 |
| 5981791 | High purity N-(4-[N,N-bis(2-iodoethyl)amino]phenoscycarbonyl)-L-glutamic acid A new salt of a prodrug useful in antibody directed enzyme prodrug therapy (ADEPT) is disclosed. A hydrogen iodide salt of the prodrug N-(4-[N,N-bis(2-iodoethyl)amino]phenoxycarbonyl)-L-glutamic acid is prepared which can be obtained in crystalline form. ... | 11/09/1999 |
| 5977398 | Viscosity conditioner A viscosity conditioner is disclosed which is comprised of a compound represented by the following formula ##STR1## where R1 to R3 each are hydrocarbyl groups which may be identical or different, m ranges from 2 to 4, and n rang... | 11/02/1999 |
| 5977170 | Elevation of HDL cholesterol by 4-[(aminothioxomethyl)hydrazono]-4-arylbutyl carbamates This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of the formula ##STR1## wherein R1, R2, and R3 are independently hydrogen, C1 ... | 11/02/1999 |
| 5968975 | Elevation of HDL cholesterol by 2-[(aminothioxomethyl)-hydrazono]-2-arylethyl carbamates This invention relates to the treatment of atherosclerosis via raising the level of HDL cholesterol by administration of a compound of the formula ##STR1## wherein: R1, R2, and R3 are independently hydrogen, C1 ... | 10/19/1999 |
| 5955499 | Phenylalkylaminoalcohol carbamates and process for preparing the same O-carbamoyl-(D/L )-phenylalaninol represented by structural formula I is pharmaceutically useful to treat diseases of the central nervous system, which is prepared by a characteristic process comprising the steps of: treating phenylalaninol with benzyl ch... | 09/21/1999 |
| 5952386 | Dihalopropene compounds, insecticides containing them as active ingredients, and intermediates for their production The present invention provides dihalopropene compounds of the general formula: ##STR1## wherein R1 is C1 -C10 alkyl or the like; L is C(.dbd.O)NH or the like; R2, R3 and R4 are indepen... | 09/14/1999 |
| 5948820 | Benzene compound and pharmaceutical use thereof A benzene compound of the formula ##STR1## wherein each symbol is as defined in the specification; an optically active isomer or salt thereof, a medicinal composition containing the same, and an immunosuppressant containing the same as the active ... | 09/07/1999 |
| 5780585 | Bacterial nitroreductase for the reduction of CB 1954 and analogues thereof to a cytotoxic form A prodrug of the formula (I): ##STR1## where R1 is a group such that the compound R--NH2 represents actinomycin D, doxorubicin, mitomycin C, or a nitrogen mustard of the formula (IV): ##STR2## a prodrug of the formula ... | 07/14/1998 |
| 5756817 | O-carbamoyl-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same The present invention relates to a racemic or enantiomerically enriched O-carbamoyl-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ... | 05/26/1998 |
| 5705640 | O-carbamoyl-(d)-phenylalaninol compounds, their pharmaceutically useful salts and process for preparing the same The present invention relates to O-carbamoyl-(D)-phenylalaninol compound represented by the following structural formula V and pharmaceutically acceptable salts thereof to treat diseases of the central nervous system: ##STR1## wherein R1 a... | 01/06/1998 |
| 5629450 | Addition salt of acyl-amino acid and -aryl amine and process for optical resolution of -arylamine To produce optically active -arylalkylamine from optically impure -arylalkylamine. Optically impure -arylalkylamine is mixed with optically active N-acyl-aspartic acid or glutamic acid in a solvent and the resulting two types of diast... | 05/13/1997 |
| 5600035 | Positive photoactive compounds based on 2,6-dinitro benzyl groups and 2,5-dinitro benzyl groups Photoreactive compounds are synthesized from 2,5- or 2,6-dintrobenzyl groups. Also disclosed are methods of synthesizing reactive monomers containing 2,5- or 2,6-dintrobenzyl groups.... | 02/04/1997 |
| 5599959 | Analogues of acetylsalicylic acid and novel uses thereof The present invention provides a salicylate analogue having the structure ##STR1## wherein R is selected from the group consisting of hydrogen, methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl; pentyl, hexyl, heptyl, octyl, nonyl, decyl, undecyl, ... | 02/04/1997 |
| 5563292 | Lipoxygenase inhibitors Novel compounds of Formula 1 ##STR1## or a pharmaceutically acceptable salt or solvate thereof are disclosed. Also disclosed are pharmaceutical compositions containing compounds of Formula 1. Methods of treating allergy, inflammation and hyperpr... | 10/08/1996 |
| 5504242 | Acyl carbamate containing a hydroxyl group and process for producing the same The present invention provides the compound containing one hydroxyl group and one acyl carbamate group per molecule, which is useful for introducing the acyl carbamate group in chemical materials. By employing the present compound, it becomes possible to ... | 04/02/1996 |
| 5463109 | Process for preparing carbamates Disclosed is a process for preparing carbamates comprising reacting carbonic acid diester with ammonia or amines in a liquid phase in the presence of at least 1 mole % of water based on carbonic acid diester.... | 10/31/1995 |
| 5434296 | Process for producing unsaturated carbamic acid esters The present invention provides a manufacturing method for unsaturated carbamic acid esters by allowing an unsaturated amide compound to react with a metallic base in an inert solvent, followed by a reaction with a halogenated formic acid ester. The invent... | 07/18/1995 |
| 5354495 | Alkenoylcarbamate compounds as elasticity, adhesion, and dispersibility enhancer A physical property-improving reagent which comprises an alkenoylcarbamate compound of the formula: ##STR1## wherein R is a hydrogen atom or a lower alkyl group, X is an oxygen atom (--O--), a sulfur atom (--S--) or a substituted or unsubstituted imi... | 10/11/1994 |
| 5326755 | Certain 2,4-pentadienamide pestacides The present application discloses pesticidally active compounds of formula I: QQ1 CR1 .dbd.CR2 CR3 .dbd.CR4 C(.dbd.X1)NR5 R6 or a salt thereof, wherein Q is an monocyclic a... | 07/05/1994 |
| 5300678 | Preparation of (107 -substituted urethano alkylcarboxylates) A process for the preparation of a ω-(O-substituted urethano)alkylcarboxylate, wherein a lactam having from 4 to 9 ring members, which can have alkyl, alkenyl, cycloalkyl, or aralkyl groups containing up to 12 carbon atoms as substituents, is reacted wit... | 04/05/1994 |
| 5286747 | 1-alkyl-2-aminotetralin derivatives Compounds of the formula ##STR1## wherein R3 and the NR1 R2 group are in a cis-position to each other and wherein Y is OH, R4 COO, (R5)2 NCOO or R6 O either in position 5 or... | 02/15/1994 |
| 5252745 | Preparation and use of iodopropargyl esters of -amino acid derivatives as antimicrobial agents Antimicrobial compounds of the formula ##STR1## wherein R1 is selected from the group consisting of H, an amine protective group, and a moiety of the formula ##STR2## wherein R2, R5, and R6 are indepen... | 10/12/1993 |
| 5223638 | Preparation of urethane and carbonate products The present invention provides a process for preparing urethanes and carbonates from an amine or an alcohol, carbon dioxide and a hydrocarbyl halide. The amine or alcohol is reacted with carbon dioxide in a suitable solvent system and in the presence of a... | 06/29/1993 |
| 5210273 | Process for the preparation of mono- and oligourethanes This invention relates to a process for the preparation of N,N-disubstituted mono- and oligourethanes by the reaction of N-aromatically, N-aliphatically, N-cycloaliphatically, and N-araliphatically substituted mono- and oligourethanes with dialkyl ca... | 05/11/1993 |
| 5200552 | Polymerizable substituted amide compound, polymer obtained therefrom and nonlinear optical material using the same The present invention provides novel polymerizable substituted amide compound which are derived from the isocyanate compounds and which are useful in the preparation of nonlinear optical materials. The polymerizable substituted amide compounds of the pres... | 04/06/1993 |
