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| Number | Title | Issue Date |
| 7476757 | Process for the synthesis of enantiomeric indanylamine derivatives A process for manufacturing (R)-propynylaminoindans, and alternatively, a process for manufacturing (S)-propynylaminoindans. The chiral propynylaminoindans include alkoxy or alkylcarbamates derivatives. The process comprises transfer or pressure hydrogenation in the... | 01/13/2009 |
| 7399880 | Process for removing farnesol from mixtures with alpha-bisabolol Process for esterification of farnesol in an initial mixture comprising alpha-bisabolol, farnesol and optionally other components, with the following steps: 1. Preparation or production of the initial mixture, 2. Adding (i) a transesterific... | 07/15/2008 |
| 6639094 | Process for producing -aminoketone derivatives A process for producing -amino-dihalogenated methyl ketone derivatives by reacting an N-protected -amino acid ester with a dihalomethyl lithium is provided. This process is suitable for the production on an industrial scale and by this proce... | 10/28/2003 |
| 6262296 | Polyisocyanate prepolymer A polyisocyanate prepolymer with isocyanate group on terminal obtainable by reaction of (A) polyoxyalkylenepolyol, (B) polyhydric alcohol having a molecular weight of 90 to 250 and the number of hydroxyl group of 2 to 3 with branched alkyl group and/or cy... | 07/17/2001 |
| 6239175 | Carbamoyloxy derivatives of mutiline and their use as antibacterials Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the... | 05/29/2001 |
| 6174885 | [6-(substituted-methyl)-3-cyclohexenyl] formamide derivative, hair growth promoter and external composition for skin A [6-(substituted-methyl)-3-cyclohexenyl]formamide derivative or a salt thereof expressed by the following Formula (I): ##STR1## wherein one of A and B is a hydrocarbon group of C10-30 expressed by R1 and the other is--(CH2 | 01/16/2001 |
| 6140531 | Method of preparing N-1-alkenyl carbonylamino compounds Describes a method of producing N-1-alkenyl carbonylamino compounds represented by the following general formula I, ##STR1## wherein R1 is the residue of an active hydrogen functional material, n is a number from 1 to a number equal to the... | 10/31/2000 |
| 6080784 | Protein kinase C modulators N Compositions with protein kinase C-modulatory, anti-inflammatory and other activities are disclosed.... | 06/27/2000 |
| 6025328 | Antitumor agents The present invention provides illudin analogs of the general formula I: ##STR1## wherein R1, R2, R3, R4, R5, and R6 have any of the values defined in the specification, and pharmaceuticall... | 02/15/2000 |
| 5955501 | Protein kinase C modulators O Compounds having anti-inflammatory and other activities are disclosed. The compounds are derived from phorboids of the diterpene- and benzolactam-classes.... | 09/21/1999 |
| 5891870 | Protein kinase C modulators Q Compositions with anti-inflammatory and other activitites are disclosed. The compositions are derived from phorboids of the diterpene- and benzolactam-classes.... | 04/06/1999 |
| 5892100 | Method for producing N-acyl carbamate The present invention provides a method for producing N-acyl carbamate in high yield. The method of the present invention comprises the step of reacting an unsaturated acid halide with a carbamate in the presence of a hindered amine. Another method of the... | 04/06/1999 |
| 5563176 | Illudin analogs useful as antitumor agents Antineoplastic illudin analogs are provided of the formula: wherein R4, R5 and R6 are (C1 -C4)alkyl, Y is H, (C1 -C3)alkyl, (R4)R5)(R6)Si or alkanoyl... | 10/08/1996 |
| 5543559 | Process for the enantioselective hydrogenation of ketosiophorone derivatives The present invention is concerned with a process for the manufacture of optically active compounds of the formula ##STR1## wherein R signifies lower alkyl, lower alkoxy, phenyl, benzyl or --NR21, R1 signifies lower a... | 08/06/1996 |
| 5504242 | Acyl carbamate containing a hydroxyl group and process for producing the same The present invention provides the compound containing one hydroxyl group and one acyl carbamate group per molecule, which is useful for introducing the acyl carbamate group in chemical materials. By employing the present compound, it becomes possible to ... | 04/02/1996 |
| 5463109 | Process for preparing carbamates Disclosed is a process for preparing carbamates comprising reacting carbonic acid diester with ammonia or amines in a liquid phase in the presence of at least 1 mole % of water based on carbonic acid diester.... | 10/31/1995 |
| 5434296 | Process for producing unsaturated carbamic acid esters The present invention provides a manufacturing method for unsaturated carbamic acid esters by allowing an unsaturated amide compound to react with a metallic base in an inert solvent, followed by a reaction with a halogenated formic acid ester. The invent... | 07/18/1995 |
| 5318989 | Cytotoxic bicyclo [7.3.1.]tridec-4-ene-2,6-diyne compounds and process for the preparation thereof The present invention relates to a novel and efficient process for the preparation of 8-hydroxybicyclo[7.3.1]tridec-4-ene-2,6-diyne ring system which is part of the aglycone of esperemicin and to novel cytotoxic antitumor agents having said bicyclic ring ... | 06/07/1994 |
| 5300678 | Preparation of (107 -substituted urethano alkylcarboxylates) A process for the preparation of a ω-(O-substituted urethano)alkylcarboxylate, wherein a lactam having from 4 to 9 ring members, which can have alkyl, alkenyl, cycloalkyl, or aralkyl groups containing up to 12 carbon atoms as substituents, is reacted wit... | 04/05/1994 |
| 5258545 | Amino acid derivative, method for preparing the same and method for preparing human osteocalcin using the same There is disclosed a novel γ-carboxyglutamic acid, a method for preparing the same and a method for preparing Gla17 human osteocalcin and Glu17 human osteocalcin or salts of these, which comprises introducing γ-carboxyglutamic acid... | 11/02/1993 |
| 5210273 | Process for the preparation of mono- and oligourethanes This invention relates to a process for the preparation of N,N-disubstituted mono- and oligourethanes by the reaction of N-aromatically, N-aliphatically, N-cycloaliphatically, and N-araliphatically substituted mono- and oligourethanes with dialkyl ca... | 05/11/1993 |
| 5194660 | Processes for producing carbamates and isocyanates Processes for producing carbamates comprise contacting a first reactant selected from primary amine components, secondary amine components, urea components and mixtures thereof; carbon monoxide; at least one organic hydroxyl component and at least one oxy... | 03/16/1993 |
| 5162575 | Preparation of isocyanates using a silver salt promoted rearrangement The present invention relates to a process for producing isocyanates which comprises reacting an N-halogenated amide with an organic base in an essentially water-free modified Hofmann reaction using a soluble silver salt promoter in the presence of an org... | 11/10/1992 |
| 5130457 | Process for the preparation of N,N-disubstituted mono- and oligourethanes N,N-disubstituted monourethanes and oligourethanes are produced by reacting (a) N-aliphatically and/or N-cycloaliphatically and/or N-araliphatically substituted monourethanes and/or oligourethanes with an alkylating agent in the presence of a solid alkali... | 07/14/1992 |
| 5105020 | Cycloalkane derivatives The invention concerns a cycloalkane derivative of the formula I, ##STR1## wherein Ar1 is optionally substituted phenyl or naphthyl; A1 is (1-6C)alkylene, (3-6C)alkenylene, (3-6C)alkynylene or cyclo(3-6C)alkylene; Ar2 is o... | 04/14/1992 |
| 5102911 | 4-Substituted HMG-CoA reductase inhibitors HMG-CoA reductase inhibitors of formulae (I) and (II) are disclosed. ##STR1##... | 04/07/1992 |
| 5101063 | Preparation of urethanes by carbonylation A process for preparation of urethanes by reacting an organic hydroxyl group-containing compound and carbon monoxide with a primary amine and oxygen in the presence of a non-noble metal or lanthanide metal catalyst system, particularly a cerium catalyst.... | 03/31/1992 |
| 5101062 | Process for producing carbamic acid esters A process for producing carbamic acid esters (N-phenyl carbamate) which comprises reacting an amino group-containing compound (aniline), oxygen, a nitro group-containing compound (nitrobenzene), a carbon monoxide-containing gas and a hydroxyl group-contai... | 03/31/1992 |
| 5091556 | Process for producing carbamates A process for preparing carbamates is disclosed, in which: a stoichiometric or higher-than-stoichiometric amount of an alkyl carbonate or a cycloalkyl carbonate is reacted with an aliphatic, cycloaliphatic or aromatic amine, in a first reaction step, by operat... | 02/25/1992 |
| 5087727 | A zulenes containing a urethane group Azulenesquaric acid dyes of the formula ##STR1## where L is substituted or unsubstituted C1 -C12 - alkylene, R1 is C1 -C20 - alkyl, C5 -C7 - cycloalkyl or substituted or unsubsti... | 02/11/1992 |
| 5055577 | Preparation of urethane products The present invention provides a process for preparing urethanes from primary or secondary amines, carbon dioxide and a diolefin. The amine is reacted with carbon dioxide to form the ammonium carbamate salt which is then reacted with a stoichiometric amou... | 10/08/1991 |
| 5015744 | Method for preparation of taxol using an oxazinone Process for the preparation of a taxol intermediate comprising contacting an alcohol with an oxazinone having the formula: ##STR1## wherein R1 is aryl, substituted aryl, alkyl, alkenyl, or alkynyl; R2 is hydrogen, ethoxyethyl, 2... | 05/14/1991 |
| 5001148 | Mevinic acid derivatives Antihypercholesterolemic activity, due to competitive inhibition of HMG CoA reductase, has been found in compounds of the formula ##STR1## wherein: R1, R2 and R3 are independently selected from: (1) alkyl, (2) substituted ... | 03/19/1991 |
| 4990649 | Azulenesquaric acid dyes that contain urethane groups Azulenesquaric acid dyes of the formula ##STR1## where L is substituted or unsubstituted C1 -C12 -alkylene, R1 is C1 -C20 -alkyl, C5 -C7 -cycloalkyl or substituted or unsubstitut... | 02/05/1991 |
| 4987130 | Substituted amine derivatives, their production and use Substituted amino derivatives represented by the formula: ##STR1## wherein R1 and R2 each stand for an acyclic hydrocarbon residue or an alicyclic hydrocarbon residue; R3 and R4 each stand for hydrogen or a... | 01/22/1991 |
| 4963583 | Beta-ionone derivatives as antifungal agents Novel 3-acyloxy-4-keto-ଲ-ionone derivatives of the formula I ##STR1## wherein Z is either the radical ##STR2## in which R1 represents C2 -C5 alkyl, C1 -C5 alkoxy-C1 -C5... | 10/16/1990 |
| 4962225 | Aspartic acid derivatives New aspartic acid derivatives include N--t-butoxycarbonyl-aspartic acid-ଲ-2-adamantyl ester--benzyl ester, N--t-butoxycarbonyl-aspartic acid-ଲ-2-adamantyl ester and benzyloxycarbonyl-aspartic acid-ଲ-2-adamantyl ester... | 10/09/1990 |
| 4910226 | Steroid 5-alpha-reductase inhibitors Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5--reductase. Also invented are intermediates used in prepar... | 03/20/1990 |
| 4871740 | Glycyrrhetic acid derivatives and use thereof A glycyrrhetic acid derivative of the formula ##STR1## wherein X and Y are hydrogen atom, respectively or X is oxygen atom together with Y, A1 is methylene or carbonyl radical, A2 is hydrogen atom, cyano, carbamoyl, carboxyl rad... | 10/03/1989 |
| 4776875 | Functional acetic acid derivatives containing phosphorus and herbicidal, growth-regulating agents containing them Compounds of the formula ##STR1## in which R1 and R2 denote alkyl, OH, CF3 or cyanoethyl, A preferably denotes --COOH, R3 denotes inter alia alkoxycarbonylalkoxy, fairly high-molecular (>C12) alk... | 10/11/1988 |
