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| Number | Title | Issue Date |
| 7435843 | Synthesis of taxol enhancers Disclosed is a method of preparing a thiohydrazide product compound from a hydrazide starting compound. The hydrazide starting compound is represented by Structural Formula (I): The thiohydrazide product compound is represe... | 10/14/2008 |
| 7288572 | Active substance combinations having insecticidal and acaricidal properties The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the form... | 10/30/2007 |
| 7217831 | Insecticide and method of controlling insects An insecticide of formula 1 and the agriculturally acceptable salts thereof, wherein: R1 is selected from the group consisting of: the group OR5 wherein R... | 05/15/2007 |
| 7205289 | Combinations of active ingredients with insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain insecticidally active compounds that together have very good insecticidal and acaricidal properties. ... | 04/17/2007 |
| 7199141 | Drugs for chronic pains Nitro-oxyderivative compounds or salts thereof having the following general formula (I): A—(B)b0—(C)c0—NO2 wherein: c0 is an integer and is 0 or 1, b0 is an integer and is 0 or 1, A=R—T1—, wherein R is the radica... | 04/03/2007 |
| 7173059 | Intermediates useful in the synthesis of HIV-protease inhibitors and methods for preparing the same Optically active 3-amino-butene and 1,2-dihydroxy-3-amino-butane intermediate compounds, useful in the synthesis of HIV-protease inhibitors and methods of preparing these intermediate compounds are disclosed. ... | 02/06/2007 |
| 7135499 | Active substance combinations having insecticidal and acaricidal properties The present invention relates to novel insecticidally and acaricidally active compound combinations of N2-[1,1-dimethyl-2-(methylsulphonyl)ethyl]-3-iodo-N1-{2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl}phthalamide of the form... | 11/14/2006 |
| 7105545 | N-p-propargyloxyphenethyl-thioacetic acid amides The invention relates to N-propargyloxy-phenethyl thioacetic acid amide derivatives of the general formula (I) including the optical isomers thereof and mixtures of such isomers, wherein R1 is hydrogen, alkyl, cycloalkyl or optionally substituted aryl, R | 09/12/2006 |
| 7084138 | Active ingredient combinations with insecticidal and acaricidal properties The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing (a) cyclic ketoenols having the formula in which the gro... | 08/01/2006 |
| 7034015 | Aminobenzoephenones The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating patients comprising administering said compounds, and to the use of said ... | 04/25/2006 |
| 6946474 | Nitrogen-containing compounds and their use as glycine transport inhibitors The present invention provides trichloroethyl-sulfonylurea-containing compounds that inhibit glycing transporters, pharmaceutical compositions comprising such compounds, methods for using such compounds for inhibiting glycine transporters and methods for using such ... | 09/20/2005 |
| 6878845 | Oligomers from multifunctional acrylates Oligomers from multifunctional acrylates and organonitro compounds are provided. Films obtained from crosslinked oligomers of the present invention are useful as protective or decorative coatings as well as components in adhesives and composites. ... | 04/12/2005 |
| 6838472 | Substituted urea retinoid agonists The current invention provide novel compounds, methods of treating or preventing emphysema, cancer and dermatological disorders, pharmaceutical compositions suitable for the treatment or prevention of emphysema, cancer and dermatological disorders and methods for de... | 01/04/2005 |
| 6803480 | Diphenylmethane derivatives The invention relates to novel diphenylmethane derivatives, processes for their preparation and their use in medicaments, in particular for the indications of arteriosclerosis and hypercholesterolaemia. ... | 10/12/2004 |
| 6683200 | N-substituted-N'-substituted urea derivatives and pharmaceutical compositions containing the derivatives N-Substituted-N'-substituted urea derivatives represented by the following formula, analogs thereof or pharmaceutically acceptable salts thereof are herein provided. These compounds show a TNF- production inhibitory activity. ##STR1##... | 01/27/2004 |
| 6583139 | Compounds which inhibit leukocyte adhesion mediated by VLA-4 Disclosed as compounds which bind VLA-4. Certain of these compounds also inhibit leukocyte adhesion and, in particular, leukocyte adhesion mediated by VLA-4. Such compounds are useful in the treatment of inflammatory diseases in a mammalian patient, e.g.,... | 06/24/2003 |
| 6559334 | Polymers chromatographic separation of enantiomers The invention relates to novel optically active polymerizable dipeptides, to the process for the preparation thereof, to the polymerization thereof and to the use of the polymers as adsorbents for the chromatographic separation of enantiomers.... | 05/06/2003 |
| 6534546 | Aniline derivatives possessing an inhibitory effect of nitric oxide synthase Compounds represented by the general formula (1): ##STR1## (where R1 is SR6 or NR7 R8, where R6 is typically an alkyl group having 1-6 carbon atoms, R7 is a hydrogen atom, an alkyl group having ... | 03/18/2003 |
| 6525093 | Compounds to treat diabetes and associated conditions Compounds are provided that lower blood glucose concentrations, lower serum triglyceride concentrations, lower systolic blood pressure, and increase glucose uptake by adipose tissue, but do not affect the expression of PPAR-γ by adipose tissue.... | 02/25/2003 |
| 6472430 | Amino thioxomethyl amino oxyacetic acid derivatives Antiatherosclerotic compounds are provided which have the following structure: ##STR1## wherein R is lower alkyl; R1 is hydroxy, amino, or lower alkoxy, R2 and R3 are each independently hydrogen, alkyl or aryl; Ar is phenyl, in... | 10/29/2002 |
| 6455581 | -and ଲ-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors - and ଲ-amino acid hydroxyethylamino sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease.... | 09/24/2002 |
| 6444850 | Fungicidial compounds having a fluorovinyloxphyenyl moiety and process for the preparation thereof A fungicidal compound of formula (I) having a fluorovinyloxyphenyl moiety and stereoisomers thereof are useful for protecting crops from fungal diseases: ##STR1## wherein: X is CH or N; Y is O or S; Z is O or NH; R1 is hydrogen or CF3 | 09/03/2002 |
| 6420603 | Process for the preparation of n,n'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2, 4,6-triiodo-1, 3-benzenedi carboxamide A novel process for the preparation of N,N'-bis[2,3-dihydroxypropyl]-5-[(hydroxyacetyl) methylamino]-2,4,6-triiodo-1, 3-benzenedi carboxamide of formula (I), commonly known as lomeprol, a novel non-ionic contrast agent which shows very good safety an... | 07/16/2002 |
| 6407100 | Fungicidal aromatic oximes The invention relates to novel compounds of the formula ##STR1## in which R1 is C1-4 alkyl and (Y--X) is CH2, C1-2 alkylthio-CH.dbd. or C1-2 alkyl-ON.dbd. and Z is an aldimino or ketimino group, and t... | 06/18/2002 |
| 6388122 | Tryptase inhibitor and novel guanidino derivatives A tryptase inhibitor comprising as an active ingredient at least one member selected from among guanidinoaliphatic acid derivatives of the formula (I), guanidinobenzoic acid derivatives of the formula (II), guanidinophenol derivatives of the formula (III)... | 05/14/2002 |
| 6331627 | Intermediates of benzoxazinone derivatives and preparation thereof The present invention relates to novel antiobesity and hypocholesterolemic compounds, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptab... | 12/18/2001 |
| 6310095 | Inhibitors of protein isoprenyl transferases Compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein R1 is (a) hydrogen, (b) loweralkyl, (c) alkenyl, (d) alkoxy, (e) thioalkoxy, (f) halo, (g) haloalkyl, (h) aryl-L2 --, and (i) heterocyclic-L | 10/30/2001 |
| 6284914 | Highly water-soluble metalloproteinase inhibitors New compounds of general formulae (III), (IV) and (V). ##STR1##... | 09/04/2001 |
| 6265590 | N-2-(4-nitrophenylsulfonyl)ethoxycarbonyl-amino acids Protected amino acid derivatives of general formula (I) ##STR1## and methods for the prepatation of the derivatives are provided.... | 07/24/2001 |
| 6265603 | Inhibitors of isoprenyl transferase Peptidomimetic isoprenyl transferase inhibitors R6SCHR1'CHR1WCHR2YC(:X)NR3CHR5COR4 wherein R1=OH, H, alkyl, amino group or R1 and R6 together form a heterocyclic ring; R1'=H, alkyl, aryl; R2=H, alkyl, arylalkyl, heteroarylalkyl; R3=H, alkyl, arylalkyl; R4... | 07/24/2001 |
| 6239308 | Method for producing -hydroxy-ଲ-aminocarboxylic acids The present invention provides a simple and inexpensive method for producing -hydroxy-ଲ-aminocarboxylic acids and their esters. An ester of an N-protected -amino acid ester is converted into a ଲ-ketosulfoxide, which is then processed ... | 05/29/2001 |
| 6235922 | Processes and intermediates for preparing benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP Compounds having the following formula I, and pharmaceutically acceptable salts thereof, including dual inhibitors of ACE and NEP and selective ACE inhibitors: ##STR1## wherein: Y1 and Y2 are each independently hydrogen, alkyl, aryl,... | 05/22/2001 |
| 6166072 | Amino acid derivatives Described herein are compounds having the general formula: ##STR1## wherein: Ar1 and Ar2 are independently selected aryl groups, optionally substituted with substituents selected from the group consisting of alkyl, cycloalkyl, a... | 12/26/2000 |
| 6153650 | Substituted gamma aminobutyric acids as pharmaceutical agents Novel gamma aminobutyric acids of formula (I) are disclosed and are useful as agents in the treatment of epilepsy, faintness attacks, hypokinesia, cranial disorders, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorder... | 11/28/2000 |
| 6066754 | Process for manufacturing N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives using N,N-dialkylarylamine as catalyst The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an organic solvent and a catalytic amount of a N,N-dialkylarylamine, to produce ... | 05/23/2000 |
| 6054457 | Benzamide derivatives and their use as vasopressin antagonists This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc, and represented by general formula (I): ##STR1## wherein R1 is aryl optionally substituted with lower alkoxy, etc., R2 is lower... | 04/25/2000 |
| 6030803 | Dibenzodihydropyridinecarboxylic esters and their use in chemiluminescent assay methods Dibenzodihydropyridinecarboxylic esters are provided which comply with formula (1) or (2), wherein: R1 is substituted alkyl or cyano; R2 and R3 are independently hydrogen, alkyl, substituted alkyl, aryl or substituted aryl... | 02/29/2000 |
| 6028131 | Antioxidants containing phenol groups and aromatic amine groups The invention relates to compounds of the formula I ##STR1## in which R is C1 -C18 alkyl, C5 -C8 cycloalkyl, C7 -C9 phenylalkyl, --CH2 --A--R2 or a group of the f... | 02/22/2000 |
| 6013829 | Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl -3- phenyl propanoic acid, application to the synthesis of N-(mercaptoacyl) amino acid derivatives Process for the asymmetric synthesis of S-acyl derivatives of 2-mercaptomethyl-3-phenylpropanoic acid of formula (I): characterized in that it comprises the steps consisting in: a) preparing the diol (VI) by reduction of a malonic ester (V) in the presenc... | 01/11/2000 |
| 5994539 | Mercapto acyl aminoacid derivatives endowed with dual ACE-NEP inhibitory activity, useful in the treatment of cardiovascular diseases Compounds of formula ##STR1## wherein R, R1, R2, R3, R4, m and n have the meanings reported in the description, processes for their preparation and pharmaceutical compositions which contain them as active i... | 11/30/1999 |
