Class 560/148 - Carbamic acid

Subclass of Class 560 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein the acid radical contains nitrogen directly
No. of patents: 144
Last issue date: 02/19/2008

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Number	Title	Issue Date
7332600	Process for the preparation of crystalline imipenem The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity, which comprises dissolving crude imipenerm in warm water to which some base has been added to obtain a solution, subjecting the re...	02/19/2008
7317040	Nitric oxide synthase inhibitor phosphate salt A compound of formula (I): namely (2S)-2-amino-4-{[2-(ethanimidoylamino)ethyl]thio}butanoic acid, compound with phosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relat...	01/08/2008
7241885	Process for the isolation of crystalline imipenem The present invention relates to a cost effective and industrially advantageous process for the preparation of imipenem of high purity comprising the steps of treating an aqueous solution containing imipenem with an organic solvent, wherein the imipenem is not lyoph...	07/10/2007
7160845	Dithiocarbamate derivatives useful as lubricant and fuel additives Dithiocarbamate derivative compounds, useful as multifunctional additives for lubricating oils and fuels, are provided and are derived from a reaction product obtained from (a) a di(hydrocarbyl)thiocarbamate intermediate derived from the reaction of a dihydrocarbyla...	01/09/2007
7102013	Methods of making amidino compounds useful as nitric oxide synthase inhibitors Method of making an alpha-amino acid compound having the structure of Formula 32: comprising treating under hydrolyzing conditions a hydantoin compound having the structure of Formula 33:	09/05/2006
7037941	Alpha-and Beta-amino acid hydroxyethylamino sulfamic acid derivatives useful as retroviral protease inhibitors Certain Alpha- and Beta-amino acid hydroxyethylamino sulfamic acid derivatives represented by the following formula are useful as retroviral protease inhibitors: ...	05/02/2006
6927036	Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof Disclosed is a method for synthesizing 1-(acyloxy)-alkyl derivatives of primary or secondary amine drugs from 1-acyl-alkyl derivatives of primary or secondary amine drugs, which typically proceeds stereospecifically, in high yield, does not require the use of activa...	08/09/2005
6646150	Processes for producing (aminomethyl)trifluorocarbinol derivatives The present invention provides a process for industrially producing (aminomethyl)trifluoromethylcarbinol derivatives, in particularly, optically active compounds thereof, which are useful as starting compounds for drugs such as protease inhibitors, etc....	11/11/2003
6620848	Nitric oxide synthase inhibitors The present invention relates to novel amidino compound of formula (I): ##STR1## to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible ...	09/16/2003
6380358	Guanidinylation reagents Trisubstituted N-protected guanidines and methods for use as guanidinylating reagents to yield N-protected guanidine derivatives....	04/30/2002
6369272	Nitric oxide synthase inhibitors The present invention relates to novel amidino compound of formula (I). ##STR1## to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use as selective inhibitors of inducible ...	04/09/2002
6359061	Amide compound libraries Amide compounds of formula (I), combinatorial libraries of amide compounds and methods of preparing the same are provided. Libraries of the invention are useful for screening in biological assays in order to identify pharmaceutically useful compounds. ...	03/19/2002
6239175	Carbamoyloxy derivatives of mutiline and their use as antibacterials Derivatives of mutiline of formula (1A) and pharmaceutically acceptable salts and derivatives thereof, in which R1 is ethyl or vinyl, Y is a carbamoyloxy group, in which the N-atom is unsubstituted, or mono- or di-substituted, are useful in the...	05/29/2001
6184412	Process for manufacture of N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives in the presence of N,N-dialkylarylamine catalyst and aqueous solvent The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an aqueous solvent and a catalytic amount of a N,N-dialkylarylamine, to produce ...	02/06/2001
6169200	Method for producing ଱-hydroxy-ଲ-aminocarboxylic acids The present invention provides a simple and inexpensive method for producing ଱-hydroxy-ଲ-aminocarboxylic acids and their esters. An ester of an N-protected ଱-amino acid ester is converted into a ଲ-ketosulfoxide, which is then processed ...	01/02/2001
6117826	Dithiocarbamyl derivatives useful as lubricant additives Dithiocarbamyl derivatives, useful as multifunctional additives for lubricating oils, of the formula ##STR1## wherein Q is ##STR2## R1 and R2 are each independently C1 -C30 n-alkyl, C3 ...	09/12/2000
6072075	Guanidinylation reagents Trisubstituted N-protected guanidines and methods for use as guanidinylating reagents to yield N-protected guanidine derivatives....	06/06/2000
6066754	Process for manufacturing N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives using N,N-dialkylarylamine as catalyst The present invention provides a process for making N-alkoxy(or aryloxy)carbonyl isothiocyanate derivatives by reacting a chloroformate with a thiocyanate, in the presence of an organic solvent and a catalytic amount of a N,N-dialkylarylamine, to produce ...	05/23/2000
6040338	N,n-bis(sulfonyl)hydrazines useful as antineoplastic agents The present invention relates to a compound of the formula wherein R1 and R2 are selected from lower alkyl groups having 1-6 carbon atoms, substituted or unsubstituted aryl groups, and unsaturated alkyl groups having 1-6 carbon atoms...	03/21/2000
5869725	Derivatives of aminosulfonic acids, utilization of the same in the synthesis of pseudopeptides and process for their preparation Derivatives of gamma-amino-alpha,beta-unsaturated sulfonic acids, a process for the preparation of the same and their utilization in the synthesis of pseudopeptides characterized by the presence of at least a sulfonamide type bond conjugated to a double b...	02/09/1999
5676923	Substituted DTPA monoamides of the central carboxylic acid group and their metal complexes Diethylenetriaminepentaacetic acid monoamide derivatives, their complexes and complex salts, containing an element of atomic numbers 21-29, 31, 32, 39, 42-44, 49 or 57-83, pharmaceutical agents containing these compounds, their use as contrast media and p...	10/14/1997
5629440	Lubricant composition A composition comprising a) a lubricant or a hydraulic fluid and b) at least one compound of the general formula I ##STR1## in which x=1 or 2 and, if x=1, R is as defined for R1 or R3 --O-- or, if x=2, R is as defined for R8, ...	05/13/1997
5523463	Method of producing halogenated and alpha-aminoalchohols A process for the manufacture of N-protected ଱-aminoketones and N-protected ଱-aminoalcohols of the formula ##STR1## wherein X is halogen, one of Q1 and Q2 is hydrogen and the other is hydroxy or Q1 and Q	06/04/1996
5510378	Retroviral protease inhibitors Hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease....	04/23/1996
5475027	Retroviral protease inhibitors Urea-containing hydroxyethylamine compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease....	12/12/1995
5442087	Polymers having N,N-disubstituted sulfonamide pendent groups and use thereof The invention relates to monomers of the formulae R1 --SO2 --N(CO--OR2)--R3--O--CO--CR4 .dbd.CH2 and R1 --N(CO--OR2)--SO2 --R3 --O--CO--CR4 .dbd.CH	08/15/1995
5414120	Polyether-substituted imide compounds and their use The present invention relates to novel polyether-substituted compounds of imides and their use as surface-active agents....	05/09/1995
5414017	Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same Compounds of the formula ##STR1## wherein m is zero or 1; n is zero, 1 or 2; p is zero or 1 to 6 provided that m and p are not both zero; R3 is hydrogen, acyl, or benzyl; and R1 is hydrogen, alkyl, phenyl, substituted phenyl, ph...	05/09/1995
5254715	Aminosulfonyl carbamates A compound of the following general formula which is useful in treating hypocholesterolemia and atherosclerosis: ##STR1## wherein X is oxygen or sulfur; R is hydrogen, alkyl having from 1 to 8 carbon atoms, or benzyl; R1 is phenyl, substit...	10/19/1993
5252745	Preparation and use of iodopropargyl esters of ଱-amino acid derivatives as antimicrobial agents Antimicrobial compounds of the formula ##STR1## wherein R1 is selected from the group consisting of H, an amine protective group, and a moiety of the formula ##STR2## wherein R2, R5, and R6 are indepen...	10/12/1993
5227401	Ethynyl alanine amino diol compounds for treatment of hypertension Compounds characterized generally as ethynyl alanine amino diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I ##STR1## wherein A is selected from CO and SO2	07/13/1993
5223535	Propargyl glycine amino propargyl diol compounds for treatment of hypertension Compounds characterized generally as propargyl glycine amino propargyl diol derivatives are useful as renin inhibitors for the treatment of hypertension. Compounds of particular interest are those of Formula I ##STR1## wherein A is selected from CO a...	06/29/1993
5219478	Lubricating oil containing O-alkyl-N-alkoxycarbonylthionocarbamate salts of dithiobenzoic acid The addition of an O-alkyl-N-alkoxycarbonylthionocarbamate salt of dithiobenzoic acid to a lubricating oil imparts antiwear and/or antioxidation performance to the oil....	06/15/1993
5209930	Preparation and use of N-iodopropargyl oxycarbonyl amino acid esters and derivatives as antimicrobial agents Antimicrobial compounds of the formula ##STR1## wherein R1 is selected from the group consisting of H, lower (C1 -C4)alkyl, alkyl aryl, CH2 OR, CH2 SR, and CH(CH3)OR; and R, R2	05/11/1993
5198569	Process for the preparation of optically active aliphatic hydroxycarboxylic acids The asymmetric hydrogenation of aliphatic ଱-keto esters in the presence of rhodium catalysts which contain as chiral ligand a diphosphine of formula IV (R3)2 P--Q--P(R3)hd 2 (IV) wherein R3	03/30/1993
5194673	Process of alkoxy and aryloxy isothiocyanate preparation Alkoxy and aryloxy isothiocyanates are produced by the reaction of a haloformate and an alkali or alkaline earth metal thiocyanate in the presence of water and (i) a catalyst comprising a six membered mononuclear or ten membered fused polynuclear aromatic...	03/16/1993
5187293	Glycerin derivatives Glycerine derivatives of the formula ##STR1## wherein the residues R1, R2 and R3 have the significance given in the description, and their hydrates, which inhibit blood platelet activating factor (PAF), are described....	02/16/1993
5185368	Polyethylene glycol carbamates Compounds of the formula ##STR1## in which R is alkyl having up to 4 carbon atoms, n has an average value of at least 9, X is a radical of the formula --C(.dbd.O)--(NH--SO2)m -- in which m is 0 or 1 and, if m is 1, the carb...	02/09/1993
5130468	Process for the preparation of a dipeptide isostere A process and intermediates useful for the preparation of (E)-alkene dipeptide isosteres are disclosed....	07/14/1992
5099058	N, N-disubstituted oligourethanes and polyurethanes, a process for their preparation, and their use in the production of plastics The present invention relates to N,N-disubstituted compounds containing urethane groups and terminal hydroxyl groups corresponding to the general formula ##STR1## wherein X is the residue of a strong memobasic or polybasic acid remaining after d...	03/24/1992

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Class 560/148 - Carbamic acid