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| Number | Title | Issue Date |
| 7250159 | Compositions comprising at least one ester of at least one hydroxylated aliphatic compound Compositions comprising at least one ester which comprises at least one aromatic group, which is liquid at room temperature and which is derived from esterification with (i) at least one aromatic acid of (ii) at least one hydroxyl group of at least one hydroxylated ... | 07/31/2007 |
| 7115728 | Human peroxisome proliferator activated receptor γ The present invention relates to a novel human peroxisome proliferator activated receptor, hPPARγ. hPPARγ differs from the mouse peroxisome proliferator activated receptor γ in the nucleotide sequence and the amino acid sequence. The invention provides isolated, ... | 10/03/2006 |
| 7098025 | Human peroxisome proliferator activated receptor gamma (pparγ) gene regulatory sequences and uses therefor This invention relates to the isolation and cloning of the promoter and other control regions of human PPARγ gene. It provides a method for identifying and screening for agents useful for the treatment of diseases and pathological conditions affected by the level o... | 08/29/2006 |
| 6706259 | Hydrolytically stable esters The present invention deals with the certain novel esters derived from a specific 36 carbon diol and fatty acids, which unlike other esters are surprisingly stable to hydrolysis and consequently of interest in high and low pH applications. ... | 03/16/2004 |
| 6537531 | Hydrolytically stable esters The present invention deals with the certain novel esters derived from a specific 36 carbon diol and guerbet acids, which unlike other esters are surprisingly stable to hydrolysis and consequently of interest in high and low pH applications.... | 03/25/2003 |
| 6420596 | Process for the selective esterification of tertiary alcohol by an acid anhydride using a reusable solid catalyst This invention provides a process for the selective esterfication of a tertiary alcohol(I) by an acid anhydride(II) to produce corresponding tertiary ester(III) and carboxylic acid(V), using a reusable solid catalyst(IV) comprising one or more halides of ... | 07/16/2002 |
| 6313088 | 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.... | 11/06/2001 |
| 6083984 | Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in the treatment of various disorders Two new forms of prodrug for phenylacetate, of even congeners of phenylalkanoic acid and phenylalkenoic acids, which are the phenylalkanoic or phenylalkenoic esters of glycerol, or the ethyl esters of phenylalkanoic acid or phenylalkenoic acids. These for... | 07/04/2000 |
| 6031015 | Dental materials based on liquid crystalline monomers A dental material based on polymerizable monomers is described which contains at least one polymerizable monomer which has liquid crystalline properties. Compared with traditional materials, the dental material displays a lower decrease in volume upon pol... | 02/29/2000 |
| 6025511 | Method of inhibiting parasitic activity A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myrist... | 02/15/2000 |
| 5998642 | Thienyl-containing fatty acid glycosyl phosphatidylinosital analogues used for inhibiting parasitic activity A method of inhibiting parasitic activity is disclosed in which the biosynthesis, structure and/or function of the glycosyl phosphatidylinositol (GPI) anchor of said parasite may be affected by incorporating into said GPI anchor selected analogs of myrist... | 12/07/1999 |
| 5968979 | Triglycerides and ethyl esters of phenylalkanoic acid and phenylalkenoic acid useful in treatment of various disorders Two new forms of prodrug for phenylacetate, of even congeners of phenylalkanoic acid and phenylalkenoic acids, which are the phenylalkanoic or phenylalkenoic esters of glycerol, or the ethyl esters of phenylalkanoic acid or phenylalkenoic acids. These for... | 10/19/1999 |
| 5959130 | Castor based benzoate esters Compositions of matter comprising castor-based benzoate esters, including benzoate esters of castor oil, benzoate esters of hydrogenated castor oil, benzoate esters of cetyl ricinoleate, and benzoate esters of octyl hydroxy stearate. The benzoate esters o... | 09/28/1999 |
| 5817845 | Methods for stereospecific synthesis of 11,13-cis polyene esters Methods for stereospecific synthesis of 9-cis olefins and retinoids. In one particular aspect, a cis olefin is generated via a lactol ring opening with complete retention of double bond configuration.... | 10/06/1998 |
| 5780676 | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors Compounds, compositions, and methods for modulating processes mediated by Retinoid X Receptors using retinoid-like compounds which have activity selective for members of the subclass of Retinoid X Receptors (RXRs), in preference to members of the subclass... | 07/14/1998 |
| 5767299 | Contrast agents The invention relates to compounds of formula (I): ##STR1## wherein R1, R2 and R3 are independently selected from: (i) saturated or unsaturated fatty acyl groups, preferably having from 14 to 24 carbon atoms, more pre... | 06/16/1998 |
| 5654452 | Lipophilic contrast agents for use in hepatocyte-selective oil-in-water emulsions Aromatic acid-derived lipophilic polyhalogenated compounds are provided for use as contrast agents in diagnostic imaging or as therapeutic agents. These compounds are particularly useful when incorporated into an oil-in-water emulsion for tissue-specific ... | 08/05/1997 |
| 5482523 | Mannich condensation products of poly(oxyalkylene) hydroxyaromatic ethers and fuel compositions containing the same Mannich condensation products prepared by the condensation of a compound of the formula: ##STR1## wherein R1 is hydrogen, hydroxy, lower alkyl or lower alkoxy; R3 and R4 are independently hydrogen or lower alkyl; R | 01/09/1996 |
| 5453525 | Carboxylic esters for the preparation of a bicyclic decalin ketone Perhydro-5,5-8a-trimethyl-2-naphthalenone is prepared by acid cyclization of carboxylic esters of formula ##STR1## having a double bond in one of the positions indicated by the dotted lines and wherein symbol R designates a C1 -C6 | 09/26/1995 |
| 5440059 | Clay-catalyzed synthesis of aryl-substituted fatty acids and fatty esters and compositions related thereto A novel method for preparing an aryl-substituted fatty acid or fatty ester is disclosed. According to the method, an olefinic composition selected from among mono-unsaturated fatty acids, mono-unsaturated fatty esters and mixtures thereof is introduced to... | 08/08/1995 |
| 5306730 | Botulinum toxin neutralizer A botulinum toxin neutralizer comprising at least one fatty acid having the number of carbon atoms of at least 12. Such a fatty acid may be any of saturated fatty acids such as lauric acid, myristic acid, palmitic acid, stearic acid, nonadecanoic acid, ar... | 04/26/1994 |
| 5274170 | Substituted benzophenone stabilizers Compounds of the formula ##STR1## in which R is hydrogen or hydroxyl, R1 is alkyl, alkoxy, amino or aryl, and R2 is hydrocarbylcarbonyl or hydrocarbylsulfonyl, are highly suitable for stabilizing magenta couplers in photographic... | 12/28/1993 |
| 5266713 | Aryl alkenoic acid derivatives as leukotriene antagonists Aryl alkenoic acid derivatives, and physiologically acceptable salts thereof, are provided which are potent leukotriene antagonists and may be used for the treatment of circulatory diseases and preferably for respiratory diseases such as asthma. The deriv... | 11/30/1993 |
| 5175338 | Isocarbacyclin derivatives and their pharmaceutically acceptable salts thereof An isocarbacyclin derivative represented by the following formula [VII'] ##STR1## wherein A represents, a hydrocarbylcarboxylate group, a carboxymethoxycarbonyl group, an amide group, an acyloxymethyl group or a hydroxymethyl group; R4 rep... | 12/29/1992 |
| 5093042 | Polyiodinated triglyceride analogs as radiologic agents Novel iodinated arylaliphatic triglyceride analogs as radiologic agents are liver and hepatocyte site-specific. The triglyceride backbone structure is preferably 1,3-disubstituted or 1,2,3-trisubstituted with, in some embodiments, a 3-substituted-2,4,6-tr... | 03/03/1992 |
| 5034161 | Synthesis of aryl-substituted aliphatic acids A method for preparation of aryl-substituted aliphatic hydrocarbons is disclosed. The method comprises reacting in the presence of a solid superacid resin catalyst an unsaturated aliphatic hydrocarbon in liquid form with an aromatic hydrocarbon that is su... | 07/23/1991 |
| 5025017 | Seco-mevinic acid derivatives useful as antihypercholesterolemic agents and new intermediates Seco-mevinic acid derivatives are provided which has the structure ##STR1## including all stereoisomers thereof, wherein Z is ##STR2## R is H, alkali metal or lower alkyl, R1 is H, lower alkyl, aryl, lower alkoxy, cycloalkyl, heteroar... | 06/18/1991 |
| 4900478 | Novel retinoids The novel compounds of the formula Ret-OA I wherein Ret is the acyl residue of a retinoid carboxylic acid, A is a residue (--CHR)--CH2 O)n R1, (--CH2)m SR | 02/13/1990 |
| 4873075 | Polyiodinated triglyceride analogs as radiologic agents Novel iodinated arylaliphatic triglyceride analogs, as radiologic agents are liver and hepatocyte site-specific. The triglyceride backbone structure is preferably 1,3-disubstituted or 1,2,3-trisubstituted with, in some embodiments, a 3-substituted-2,4,6-t... | 10/10/1989 |
| 4780251 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8-nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 10/25/1988 |
| 4648996 | Phenyl substituted-2,4,6,8-nonatetraenoic acid The compounds 9-phenyl-3,7-dimethyl-2,4,6,8 nonatetraenoic acids wherein the phenyl group is substituted with an alkyl, aminoalkyl, hydroxyalkyl, alkoxy, hydroxyalkylamino, and a hydroxy alkoxy group, and derivatives thereof which are used as disease modi... | 03/10/1987 |
| 4597906 | Surface-active compounds on the basis of arylated fatty substances and their use Compounds of the formula in which A is the radical of an oxaryl-modified (modified with an aryl group containing a hydroxyl group) fatty alcohol, i.e., the radical of an arylated fatty alcohol, or is the radical of an oxaryl-modified (again, modified with... | 07/01/1986 |
| 4570011 | Preparation of cyclobutene substituted aromatic hydrocarbons The invention is a process for the preparation of an aromatic hydrocarbon with a cyclobutene ring fused to the aromatic hydrocarbon which comprises, dissolving an ortho alkyl halomethyl aromatic hydrocarbon in an inert solvent and pyrolyzing the solution ... | 02/11/1986 |
| 4564476 | Aryl fatty acid leukotriene synthesis inhibitors Aryl fatty acid compounds of the formula (I) ##STR1## wherein R1, R2, R3, X, and Y are as defined herein are novel and useful in the treatment of allergic and inflammatory disorders.... | 01/14/1986 |
| 4526723 | Biocidal enol esters of non-ortho substituted 2-aryl-1-3-cycloalkanedione compounds Non-ortho substituted 2-aryl-1,3-cycloalkanedione enol ester compounds exhibit outstanding acaricidal and herbicidal activity.... | 07/02/1985 |
| 4524059 | Fatty acid analogs In one aspect, a radioactively labeled analog of a fatty acid which is capable of being taken up by mammalian tissue and which exhibits an in vivo beta-oxidation rate below that with a corresponding radioactively labeled fatty acid.... | 06/18/1985 |
| 4523042 | Derivatives of alpha-alkyl polyolefinic carboxylic acid useful in the treatment of psoriasis This invention relates to novel compounds having pharmaceutical activity and having the general structure ##STR1## wherein the Z, R1, R2, R3, R4, n and m are defined within.... | 06/11/1985 |
| 4505930 | Alpha-alkyl polyolefinic carboxylic acids and derivatives thereof useful in the treatment of psoriasis and allergic responses Polyolefinic compounds represented by the general formula ##STR1## in which R and R1 are each hydrogen or an alkyl group of from 1 to 5 carbon atoms; R2 is an alkyl group of from 1 to 5 carbon atoms; R3 is hydroxyl, a... | 03/19/1985 |
| 4473544 | Radio-iodine-labelled omega phenyl fatty acids Radio-iodine-labelled omega-phenyl fatty acid of the formula: ##STR1## in which: X is an alkylene group having from 6 to 20 carbon atoms; R is hydrogen or an alkyl or alkoxy group having 1 or 2 carbon atoms; Y is hydrogen, an alkali metal ion, alkali... | 09/25/1984 |
| 4472430 | Alpha-alkyl polyolefinic carboxylic acids and derivatives thereof useful in the treatment of psoriasis Polyolefinic compounds, useful in the treatment of psoriasis, are disclosed. The compounds are represented by the general formula ##STR1## in which R and R1 are each hydrogen or an alkyl group of from 1 to 5 carbon atoms; R2 is ... | 09/18/1984 |
