...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
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| Number | Title | Issue Date |
| 7041839 | Steroidal antiestrogens and antiandrogens and uses thereof The present invention comprises the design, synthesis and development of a new class of chemotherapeutic agents for prophylactic and therapeutic treatments in a mammal, particularly a human, believed to be at risk of suffering from a hormone-responsive disorde. In a... | 05/09/2006 |
| 6989378 | Testosterone derivative The invention is the novel androgen (7α,17β)-7-methyl-17-[(1-oxoundecyl)oxy]estr-4en-3one (MENT undecanoate). This compound distinguishes favourably from other testosterone derivatives in that it has a good solubility in oily media. It particularly exhibits a good... | 01/24/2006 |
| 6677329 | Non-aromatic estrogenic steroids with a hydrocarbon substituent in position 11 Disclosed are novel, selective estrogens type having a steroid skeleton with a non-aromatic A-ring and a free or capped hydroxyl group at carbon atom No. 3. The estrogens satisfy general formula (I), in which R1 is H, (C1 -C3 | 01/13/2004 |
| 5925630 | Neuroactive steroids of the androstane and pregnane series The invention relates to 3-hydroxy, 17-(un)substituted derivatives of the androstane series and 3-hydroxy, 21-substituted derivatives of the pregnane series. These derivatives are capable of acting at a recently identified site on the GRC, t... | 07/20/1999 |
| 5723455 | Antiandrogenic agents and related pharmaceutical compositions and methods of use Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compo... | 03/03/1998 |
| 4978658 | Compositions containing 5-dihydro-19-norethisterone and derivatives thereof for in vivo inhibition of aromatase A composition for in vivo inhibition of aromatase in a mammal, which comprises an in vivo inhibitory amount of a compound having the following general formula: ##STR1## wherein R1 is hydrogen or C1-4 acyl, in combination with as... | 12/18/1990 |
| 4885117 | Process for the preparation of (Z)-17-halovinyl steroids (Z)-17-halovinyl steroids of general Formula I ##STR1## wherein . . . . is a single bond or a double bond, V is a carbon-to-carbon bond or a methylene group, R1 is a hydrogen atom or a methyl group, X is a chlorine atom, a bromine atom or an ... | 12/05/1989 |
| 4307087 | Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3 is H, OH, CH3 or ... | 12/22/1981 |
| 4307086 | Branched chain and cycloaliphatic esters of the androstane and destrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3 is H, OH, CH3 or ... | 12/22/1981 |
| 4212864 | Branched chain and cycloaliphatic esters of the androstane and oestrane series and pharmaceutical compositions containing same There are disclosed branched chain and cycloaliphatic esters of steroids having the formula: ##STR1## or the 5H analog thereof, where R is H or CH3 ; R1 is H or CH3 ; R2 is H or CH3 ; R3 | 07/15/1980 |
| 4002746 | Synthesis of gon-4-enes 1. A therapeutic composition having progestational activity comprising as active ingredient a 17-aliphatic carboxylic acid ester of 17-ethynyl-18-methyl-19-nortestosterone and a pharmaceutical carrier for said compound.... | 01/11/1977 |