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| Number | Title | Issue Date |
| 7601857 | Preparation of 6-hydroxyequilenins This invention relates to a process for the preparation of 6-hydroxyequilenins, which are useful as estrogenic agents. ... | 10/13/2009 |
| 7300587 | Oxidation of heavy metal ions A water-insoluble polymeric oxidizing medium is contemplated that has a plurality of polymerized N-pyridinium vinylbenzyl triiodide or tribromide moieties whose pyridinium rings bear two substituents, R1 and R2, that are independently a hydrido... | 11/27/2007 |
| 7186671 | Particulate alumina and process for removing metal ions from water A water-insoluble polymeric oxidizing medium is contemplated that has a plurality of polymerized N-pyridinium vinylbenzyl triiodide or tribromide moieties whose pyridinium rings bear two substituents, R1 and R2, that are independently a hydrido... | 03/06/2007 |
| 7179799 | (3) and (6) substituted estrogenic compounds Novel estrogenic compounds of Formula I are provided. wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R1 is selected from the... | 02/20/2007 |
| 7067682 | 6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 06/27/2006 |
| 7002028 | 5-androsten-3β-ol steroid intermediates and processes for their preparation The present invention provides 5-androsten-3β-ol steroid intermediates and processes for their preparation. ... | 02/21/2006 |
| 6956126 | Preparation of 6-hydroxyequilenins This invention relates to a process for the preparation of 6-hydroxyequilenins, which are useful as estrogenic agents. ... | 10/18/2005 |
| 6949533 | 6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 09/27/2005 |
| 6930192 | Methods for preparing 7alpha-hydroxy-dehydroepiandrosterone The invention relates to new processes for preparing 7alpha-hydroxy-dehydroepiandrosterone of formula (1): ... | 08/16/2005 |
| 6844334 | (3) and (6) substitued estrogenic compounds Novel estrogenic compounds of Formula I are provided. wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R1 is selected from the group... | 01/18/2005 |
| 6696580 | Process for the production of 6,7-diols of steroidal compounds Steroids containing a cyclohexene moiety are efficiently oxidized to the corresponding ,ଲ-unsaturated ketone using copper iodide and t-butyl hydroperoxide. A steroid compound containing the ,ଲ-unsaturated ketone structure is effi... | 02/24/2004 |
| 6686486 | Process for effecting allylic oxidation A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal periodate and an alkyl hydroperoxide under conditions of normal as... | 02/03/2004 |
| 6660726 | Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same Novel estrogenic compounds of Formula I are provided. ##STR1## wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R1 is selected from the group consisting of hydrogen, sul... | 12/09/2003 |
| 6605591 | Treatment of subnormal bone mineral density A method of treating an individual to increase the individual's bone mineral density (BMD) is disclosed. The method includes co-administering a calcitonin-like agent and a DHEA-like agent. Also disclosed are methods for potentiating the effect of treatmen... | 08/12/2003 |
| 6384251 | Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an N-hydroxy dicarboxylic acid imide and a chromium-containing oxidant. The reaction can co... | 05/07/2002 |
| 6274746 | Process for allylic oxidation using metal hypochlorite and alkyl hydroperoxide The present invention is directed to a process for effecting the allylic oxidation of an allylic compound having at least two allylic hydrogen atoms on the same carbon atom into corresponding ,ଲ-unsaturated carbonyl compound, using a combinat... | 08/14/2001 |
| 6111118 | Process for effecting allylic oxidation A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal periodate and an alkyl hydroperoxide under conditions of normal as... | 08/29/2000 |
| 5977096 | Steroids with radical-attracting aromatic substituents, process for the production thereof and pharmaceutical compounds containing the said substances Novel substituted steroid compounds are disclosed which are more effective than known radical-trapping agents in methods of prophylaxis and therapy of radical-mediated cell damage and of treatment of diseases due to radical-mediated cell damage. The novel... | 11/02/1999 |
| 5869709 | Process for effecting allylic oxidation A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an alkali metal periodate and an alkyl hydroperoxide. The reaction can conveniently be cond... | 02/09/1999 |
| 5648507 | 14-hydroxy-4-androstene-3,6,17-trione hydrate and process for producing same Provided are stable hydrate crystals of 14-hydroxy-4-androstene-3,6,17-trione having a biological activity of human placenta-originating estrodiene synthesis enzyme inhibitory action. These hydrate crystals include two kinds of 14-hydro... | 07/15/1997 |
| 5614651 | 14-hydroxy-4-androstene-3,6,17-trione hydrate crystal and process for producing same Provided are stable hydrate crystals of 14-hydroxy-4-androstene-3,6,17-trione having a biological activity of human placenta-originating estrodiene synthesis enzyme inhibitory action. These hydrate crystals include two kinds of 14-hydro... | 03/25/1997 |
| 5354745 | Estradiol derivative-chlorambucil conjugate process for preparing the same, and pharmaceutical composition An estradiol derivative-chlorambucil conjugate of the formula (I): ##STR1## wherein R1 is alkyl or alkoxyl of 1 to 4 carbon atoms; R2 is acyl, dansyl, or alkyl; R3, R4, and R5 independently are H, ... | 10/11/1994 |
| 5296481 | Treatment process for promoting weight loss employing a substituted Ɗ 5 A method for controlling weight gain or promoting weight loss which includes the step of treating a subject with an effective weight gain controlling or weight loss promoting amount of a substituted Ɗ5-Androstene which is biologically effective for contr... | 03/22/1994 |
| 5252565 | Haloethyl-substituted steroid enzyme inhibitors The present invention is directed to a group of compounds which are haloethyl substituted steroidal enzyme inhibitors. These compounds are useful as aromatase, 19-hydroxylase, and aldosterone biosynthesis inhibitors and they are prepared from the correspo... | 10/12/1993 |
| 5202314 | 10-thioethyl-steroids A compound of the formula ##STR1## wherein R is selected from the group consisting of alkyl, alkenyl and alkynyl of up to 4 carbon atoms, Y is .dbd.O or ##STR2## R1 is hydrogen or acyl, n is 0, 1 or 2, D is .dbd.O or ##STR3## ... | 04/13/1993 |
| 5098535 | Process for preparing 14--hydroxy-4-androstene-3,6,17-trione A process for the preparation in high yield of 14-hydroxy-4-androstene-3,6,17-trione which has an aromatase inhibition activity and is useful as an antitumor agent, in which the 6ଲ-hydroxyl group of 6ଲ, 14-dihydroxy-4-andros... | 03/24/1992 |
| 5079377 | Novel androst-4-ene-3,17-dione derivatives and method for preparing same Novel androst-4-ene-3,17-dione derivatives are disclosed. The group of these compounds has biological activities, in particular, the inhibiting activity on human placenta-derived estrogen-synthesizing enzyme. Therefore these compounds are expected to be u... | 01/07/1992 |
| 4975368 | Novel androst-4-ene-3,17-dione derivatives and method for preparing same Novel androst-4-ene-3,17-dione derivatives are disclosed. The group of these compounds has biological activities, in particular, the inhibiting activity on human placenta-derived estrogen-synthesizing enzyme. Therefore these compounds are expected to be u... | 12/04/1990 |
| 4925834 | 3-methylene-4-androsten-17-ones, process for their production and pharmaceutical preparations containing them A 3-methylene-4-androsten-17-one of formula I ##STR1## wherein Ra represents a hydrogen atom or a saturated or unsaturated straight-chain or branched-chain, optionally substituted alkyl radical with 1-6 carbon atoms, in which Ra... | 05/15/1990 |
| 4898694 | 17-Hydroxy-steroids Compounds of the formulae: ##STR1## are useful as anti-cancer, anti-obesity, anti-diabetic, anti-coronary agents, anti-aging agents, anti-hypolipidemic agents and anti-autoimmune agents.... | 02/06/1990 |
| 4814327 | 11 ଲ-(4-isopropenylphenyl)estra-4,9-dienes, their production, and pharmaceutical preparations containing same 11 ଲ-(4-isopropenylphenyl)-estra-4,9-dienes of general Formula I ##STR1## wherein X is an oxygen atom or a hydroxyimino grouping N OH, R1 is a hydrogen atom or a methyl group, R2 is a hydrogen atom or an acyl residue of 1-10 carbon... | 03/21/1989 |
| 4757061 | 4-amino androstendione derivatives and process for their preparation The invention discloses 4-substituted androstendione derivatives of the following formula (I) ##STR1## wherein R is amino or substituted amino or azido, one of R1 and R2 is hydrogen and the other is hydrogen, alkyl, alkenyl or a... | 07/12/1988 |
| 4753932 | Novel 10-substituted steroids A novel steroid of the formula ##STR1## wherein X is methylene and R is an optionally substituted carbocyclic aryl or heterocyclic aryl or optionally substituted vinyl or ethynyl or X is a simple bond or --S-- and R is optionally substituted carbocyc... | 06/28/1988 |
| 4749567 | Method and product for increasing fertility in sheep using milk protein conjugates A product and method for increasing fertility in sheep. By "increasing felity" is meant increasing the potential of a flock of sheep to multiply by increasing ovulation in ewes. The product is an immunogenic conjugate of 4-androstene-3, 17-dione and a so... | 06/07/1988 |
| 4661295 | Novel radioactive estradienes Novel radioactive estradienes labelled with tritium of the formula ##STR1## wherein 3 H is tritium and R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms and acyl of an organic carboxylic acid of 1 to 10 carb... | 04/28/1987 |
| 4634695 | Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the... | 01/06/1987 |
| 4615835 | Steroid esters of N-(2-halogenethyl)-N-nitroso-carbamoylamino and acids and peptides therefore, as well as method for preparing them Steroid-N-(2-halogen ethyl)-N-nitroso-carbamoylamino acid or peptide esters of the general formula: ##STR1## where R1 and R2, which may be identical or different, mean the radical of an amino acid beyond the C atom in the beta p... | 10/07/1986 |
| 4602008 | Alkylated etiocholanolones and use as an anti-diabetic, anti-obesity and erythropoietic agent 16-Alkylated and 16-alkylated-7-hydroxy 5ଲ-androstan-3-ol-17-one, and the esters and ethers thereof, are used as an anti-diabetic, anti-obesity and erythropoietic agent in mammals.... | 07/22/1986 |
| 4529548 | 17ଲ-(substituted thio)androstenes Antiinflammatory activity is exhibited by steroids having the formula ##STR1## or the 1,2-dehydro derivative thereof, wherein R1 is alkyl, alkanoyloxyalkyl, arylcarbonyloxyalkyl, alkenyl, alkynyl, cycloalkyl, aryl or arylalkyl; R2 | 07/16/1985 |
| 4519946 | Steroids Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbons atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with th... | 05/28/1985 |
