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| Number | Title | Issue Date |
| 6174665 | Hormone replacement therapy monitoring The present invention provides methods for monitoring the effectiveness of hormone replacement therapy in a perimenopausal, early menopausal, or late menopausal woman, comprising testing for hormonal levels in a body fluid of the woman at intervals depend... | 01/16/2001 |
| 5994333 | Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a pregnane or cholane steroid, or a pharmaceutical composition containing a vomeropherin, such that... | 11/30/1999 |
| 5827842 | 14, 17-C2 -bridged norprogesterone derivatives The invention describes 14,17-C2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are, in contrast with the disclaimed compound 14,17-ethano... | 10/27/1998 |
| 5519153 | Medrogestone production A process for the production of 6,17-dimethylpregna-4,6-diene-3,20-dione which comprises isolating 3ଲ,5, 6ଲ-trihydroxy- 6,17- dimethylpregnan-20-one monomethanolate from the solution of a Grignard reaction prod... | 05/21/1996 |
| 5352808 | Process for steroid preparation A process for the preparation of a compound of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted by halogen or a nitrogen or oxygen function and alkenyl a... | 10/04/1994 |
| 5140106 | Process for the production of 3-deoxy-4-ene steroids A process for the production of 3-deoxy-4-ene steroids of the general formula I ##STR1## is described, in which R1, R2 and R3 mean a hydrogen atom or a methyl group, R4 represents a lower alkyl group, a phe... | 08/18/1992 |
| 5086047 | Novel steroids A compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl, alkylthio and haloalkyl of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms, option... | 02/04/1992 |
| 5073548 | 11 ଲ-substituted progesterone analogs A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5 , wherein R5 is C2... | 12/17/1991 |
| 4954490 | 11 ଲ-substituted progesterone analogs A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5, wherein R5 is C2-... | 09/04/1990 |
| 4913852 | Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with pregnane derivatives Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with derivatives of Ɗ-4-pregnene-3,20-dione or with derivatives of Ɗ-1,4-pregnadiene-3,20-dione of the general formulas (I), (II) and (III), having glucoco... | 04/03/1990 |
| 4871724 | Novel 11-aryloestrane and 11-arylpregnane derivatives The present invention is concerned with 11-aryloestrane and 11-arylpregnane derivatives, characterized in that these derivatives have the following structure: ##STR1## wherein R1 is an aryl group with an ##STR2## group as substit... | 10/03/1989 |
| 4870069 | 11ଲ-alkynyl-estrenes and -estradienes, their production and pharmaceutical preparations containing them 11ଲ-substituted steroids of the formula ##STR1## wherein A and B together represent a second bond between the 6-position and 7-position carbon atoms, or, respectively, are each H; X is O, two H atoms or hydroximino; Z is the residue of a pentagonal ... | 09/26/1989 |
| 4512986 | Progrestationally active steroids Novel steroids having the formula ##STR1## wherein R1 is selected from the group consisting of methyl, ethyl, and propyl; R2 is selected from the group consisting of H and methyl; R3 is selected from the group consisting o... | 04/23/1985 |
| 4501701 | 20-Isocyano-Ɗ17(20) -steroids Novel 20-isocyano-Ɗ17(20) -steroids of the formula ##STR1## wherein R1 is selected from the group consisting of (1) hydrogen, (2) alkyl of 1 to 4 carbon atoms optionally substituted with a member of the group consisting of halo... | 02/26/1985 |
| 4440684 | Process for the preparation of 6-methyl-Ɗ4,6 -3-keto steroids A process for preparing 6-methyl-Ɗ4,6 -3-keto steroids of the formula ##STR1## comprises reacting a corresponding Ɗ4 -3-keto steroid with methoxymethyl acetate (CH3 --O--CH2 --OAc) in an inert solvent ... | 04/03/1984 |
| 4424159 | Process for the synthesis of the hydroxyacetyl side-chain of steroids of the pregnane type, novel 21-hydroxy-20-oxo-17-pregnane compounds and pharmaceutical preparations containing them The present invention relates to a novel general process for synthesizing a - or ଲ-oriented hydroxyacetyl side chain of steroids of the pregnane type, which comprises treating a corresponding steroid carbaldehyde in succession with formaldehy... | 01/03/1984 |
| 4404141 | Ɗ9(11) - And Ɗ16 -21-chloro-20-keto steroids of the pregnane and D-homopregnane series, their preparation and use as intermediates for the synthesis of highly effective corticoids Ɗ16 - and Ɗ17 -21-chloro-20-keto steroids of the formula ##STR1## wherein n is 1 or 2, C1 C2 and C9 C11 represent a CC-single or CC-double bond, R1 is H or OH, R2 | 09/13/1983 |
| 4323511 | Steroid derivatives and their use in radioimmunoassays Radiolabeled steroid derivatives having the formula ##STR1## wherein St is a 6-dehydro derivative of a 3-oxo-4,5-dehydro steroid intended for radioimmunoassay, said steroid being saturated in the 1,2-position; R is hydrogen or alkyl of 1 to 3 carbon ... | 04/06/1982 |
| 4322349 | Process for preparing 6-methylene steroids A process for preparing a 6-methylene-Ɗ4 -3-keto steroid of the formula ##STR1## wherein R is hydrogen, alkoxy of up to 6 carbon atoms or acyloxy of up to 6 carbon atoms wherein the acyl group is that of a carboxylic acid, and R' is the C... | 03/30/1982 |
| 4216159 | Synthesis of 16-unsaturated pregnanes from 17-keto steroids 17-Keto steroids (I) in their protected form (IIa or IIb) are reacted with a metalated olefin (VI) to give a 21-aldehyde (IV) which is readily transformed to a 16-unsaturated pregnane (V) which is useful in the production of commercially important substit... | 08/05/1980 |
| 4172075 | Fluoro-steroids and processes for their manufacture 11,12-Unsaturated 9-fluorosteroids comprising a new class of steroid compounds are obtained by a novel process, wherein a corresponding 9-fluoro-11ଲ-hydroxysteroid is dehydrated with a reagent of the formula F3 SX in which X... | 10/23/1979 |
| 4124707 | 7-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor Novel 3,20-dioxo-7-halogeno-1,4-pregnadienes are described and their use as anti-inflammatory agents. Preferred are 7-bromo- and 7-chloro- derivatives, particularly 7-bromo- and 7-chloro-1,4-pregnadienes-11ଲ,17�... | 11/07/1978 |
| 4018774 | Steroidal [16,17-d]isoxazolidines Novel steroids having the structure ##STR1## and the 1,2-dehydro derivatives thereof, wherein R1 is hydrogen, hydroxy, alkanoyloxy, fluorine, chlorine, or bromine; R2 is alkyl or aryl; R3 is alkyl, aryl, alkanoyl, aro... | 04/19/1977 |
| 4018757 | Steroidal[16,17-c][2H]pyrroles Steroids having the structure ##STR1## and the 1,2-dehydro derivatives thereof, wherein R1 is hydrogen, hydroxy, ##STR2## fluorine, chlorine, or bromine; R2 is alkyl or aryl; R3 is aryl, cyano, alkylcarbonyl... | 04/19/1977 |
| 3933799 | 11ଲ-Halo-9,12-unsubstituted-C19 -steroids 11ଲ-Halo-9,12-unsubstituted-C19 -steroids having hormonal activity and a process for preparing same by reacting the corresponding 11-hydroxy steroid with a compound of the formula ##EQU1## where R1 and R... | 01/20/1976 |
