Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6900193 | Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents The present invention relates, inter alia, to compounds having the general formula: in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)... | 05/31/2005 |
| 6861415 | 21-substituted progesterone derivatives as new antiprogestational agents A compound having the general formula: in which: R1 is a member selected from the group consisting of —OCH3, —SCH3, —N(CH3)2, —NHCH3, —CHO, â€... | 03/01/2005 |
| 5994335 | 17-azolyl steroids useful as androgen synthesis inhibitors Androgen synthesis inhibitors, as well as methods for the use of the same to reduce plasma levels of testosterone and/or dyhydrotestosterone, and to treat prostate cancer and benign prostatic hypertrophy, are disclosed.... | 11/30/1999 |
| 5994333 | Pregnane and cholane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a pregnane or cholane steroid, or a pharmaceutical composition containing a vomeropherin, such that... | 11/30/1999 |
| 5827842 | 14, 17-C2 -bridged norprogesterone derivatives The invention describes 14,17-C2 -bridged steroids of general formula (I), ##STR1## wherein the various R groups are as defined in the specification, and wherein said steroids are, in contrast with the disclaimed compound 14,17-ethano... | 10/27/1998 |
| 5824670 | 17-deoxycorticosteroid-21-›O!carboxylic esters, processes for their preparation and pharmaceuticals containing these compounds 17-Deoxycorticoid-21-carboxylic esters of the formula I ##STR1## are described, in which A is CHOH and CHCl, CH2, C.dbd.O or 9(11) double bond; Y is H, F or Cl; Z is H, F or CH3 ; R(1) is aryl or hetaryl and R(2) is H or methyl.... | 10/20/1998 |
| 5760256 | Process for the production of 21-acyloxy-4,9 (11),16-pregnatriene-3,20-diones A process for the production of a compound of the formula ##STR1## wherein R1 is acyl of 1 to 8 carbon atoms,. The compound is formed by the reduction of an intermediary to form an alcohol, epoxidation and hydrolyzation of the alcohol to f... | 06/02/1998 |
| 5616743 | 16-methyl-ÆŠ1,4 -pregnadiene-3,20-diones A compound having the formulae selected from the group consisting of ##STR1## wherein R2 and R3 are hydrogen or R2 is fluorine and R3 is formyloxy or acetyloxy, the dotted line in 9(11) position indicates a... | 04/01/1997 |
| 5502223 | Process for preparation of ÆŠ4,9(11),16 pregnatriene-3,20-diones A process for the preparation of a compound of the formula ##STR1## wherein R1 is acyl of an organic carboxylic acid of 1 to 8 carbon atoms useful as intermediates for synthesis of therapeutically active steroids.... | 03/26/1996 |
| 5401864 | Process for preparing 21 acyloxy-ÆŠ4,9(11),16 pregnatrienes 3-20-dione A process for the preparation of a compound of the formula ##STR1## wherein R1 is acyl of 1 to 8 carbon atoms, by reducing an intermediary to form an alcohol, oxidizing the alcohol to form an aidehyde, which is subjected to the action of a... | 03/28/1995 |
| 5352808 | Process for steroid preparation A process for the preparation of a compound of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted by halogen or a nitrogen or oxygen function and alkenyl a... | 10/04/1994 |
| 5294704 | 4,9(11),17(20)-pregnatriene-3-ones A process for the production of a compound of the formula ##STR1## wherein R is an acyl group of 1 to 8 carbon atoms. The compound is formed through an intermediate compound of the formula ##STR2## wherein R1 is selected from the grou... | 03/15/1994 |
| 5264427 | 20-substituted pregnene derivatives and their use as androgen synthesis inhibitors Novel 20-substituted-pregnene derivatives, compositions containing such derivatives and methods for their use and manufacture are disclosed. The 20-substituted-pregnene derivatives inhibit the androgen biosynthesis enzymes 17(alpha)-hydroxylase/C17 | 11/23/1993 |
| 5248773 | 16-methyl-ÆŠ1,4-pregnadiene-3,20-diones A compound of the formula ##STR1## in which ##STR2## is either a 3-keto-ÆŠ4-system or a 3-keto -ÆŠ1,4-system or a 3-OR4 -ÆŠ5-system in which R4 is hydrogen or a protector group of hydroxy, R is methyl, --CH2... | 09/28/1993 |
| 5169966 | Process for producing an -acyloxy-, ଲ-unsaturated carbonyl compound and a 20-acyloxy-17(20)-methylen-21-al-steroid compound There are disclosed a process for producing an -acyloxy-,ଲ-unsaturated carbonyl compound represented by the general formula (VI): ##STR1## wherein R1, R2 and R4 are independently hydrogen atoms or ... | 12/08/1992 |
| 5116830 | Stereoisomerically pure 17-ethynyl-estra-2-en-17ଲ-ol and the 17ଲ esters thereof, methods of preparation and uses This invention relates to a stereoisomerically pure ÆŠ2 compound of the formula (I): ##STR1## wherein: R1 is hydrogen or --(C.dbd.O)--R2, wherein: R2 is an organic substituent selected from the group consisting ... | 05/26/1992 |
| 4948533 | 11a-hydroxy steroid diester The present invention relates to 21-(3-carboxy-1-oxopropoxy) -17-hydroxy-11-(3,3-dimethyl-1-oxobutoxy)pregna-1,4-diene-3, 20 dione and pharmaceutically acceptable salts thereof which are useful steroid prodrugs.... | 08/14/1990 |
| 4929395 | 16-methylation process C16 -unsaturated corticoids are readily transformed to the corresponding 16-methyl-17-hydroxy corticoids by use of a ÆŠ17 (20)-20-silyl ether.... | 05/29/1990 |
| 4920114 | 19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors 19-Fluoro- and cyano- substituted 21-hydroxyprogesterone derivatives and related compounds which are active as 19-hydroxylase inhibitors and useful as antihypertensive agents are described herein. The compounds are prepared using appropriate synthetic pat... | 04/24/1990 |
| 4917827 | Process for the preparation of 9(11)-dehydro steroids 9(11)-dehydroandrostanes and 9(11)-dehydropregnanes are prepared by dehydrating the corresponding 9-alpha-hydroxy steroid in the presence of a Lewis acid. The corresponding 8(9)-dehydro-isomer was not detectable. The resulting products are valuable interm... | 04/17/1990 |
| 4913852 | Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with pregnane derivatives Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with derivatives of ÆŠ-4-pregnene-3,20-dione or with derivatives of ÆŠ-1,4-pregnadiene-3,20-dione of the general formulas (I), (II) and (III), having glucoco... | 04/03/1990 |
| 4871724 | Novel 11-aryloestrane and 11-arylpregnane derivatives The present invention is concerned with 11-aryloestrane and 11-arylpregnane derivatives, characterized in that these derivatives have the following structure: ##STR1## wherein R1 is an aryl group with an ##STR2## group as substit... | 10/03/1989 |
| 4870069 | 11ଲ-alkynyl-estrenes and -estradienes, their production and pharmaceutical preparations containing them 11ଲ-substituted steroids of the formula ##STR1## wherein A and B together represent a second bond between the 6-position and 7-position carbon atoms, or, respectively, are each H; X is O, two H atoms or hydroximino; Z is the residue of a pentagonal ... | 09/26/1989 |
| 4668437 | Novel 20 benzcylamino pregnene derivatives and process for preparing same The invention relates to new pregnene derivatives of the general formula (I), ##STR1## wherein R1 stands for a C1-4 alkyl group; R2 stands for a hydrogen atom or a C2-4 alkanoyl group; R3 stands for a... | 05/26/1987 |
| 4634695 | Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the... | 01/06/1987 |
| 4603128 | Mineralocorticoid hormone antagonists 7-acylthio-4-pregnene-3,20-diones, active as mineralocorticoid hormone antagonists, of the formula: ##STR1## in which R1 is hydrogen, hydroxyl or acyloxy --OR2, R2 is an acyl group derived from a straight or br... | 07/29/1986 |
| 4588718 | Carboxy containing ester prodrugs of corticosteroids A compound of the formula ##STR1## wherein St represents a corticosteroid moiety bonded to the carbonyl via the 21-hydroxy group of said corticosteroid; wherein Z is a bond or --O--; wherein n is an integer from 4 to 9; wherein Q is (1) Y--CH2 ... | 05/13/1986 |
| 4551278 | Preparation of 20-keto-ÆŠ16 -steroids A novel process for the preparation of 20-keto-ÆŠ16 -steroids comprising reacting a 17-(isocyanosulfonylmethylene)-steroid with an alkylating agent QR4 wherein R4 is an organic group and Q is a group or atom readily displa... | 11/05/1985 |
| 4548749 | Process for the preparation of 21-hydroxy-20-keto-ÆŠ16 -steroids and new intermediate compounds formed in this process A novel process for the preparation of 21-hydroxy-20-keto-ÆŠ16 -steroids comprising reacting a 17-(isocyanosulfonylmethylene)-steroid with an aldehyde and an alcohol to form a 17-(2-alkoxy-3-oxazolin-4-yl)-ÆŠ16 -steroid and subjectin... | 10/22/1985 |
| 4547493 | Novel 11ଲ-substituted-19-nor-steroids Novel 19-nor-steroids of the formula ##STR1## wherein R1 is an organic group of 1 to 18 carbon atoms optionally containing at least one heteroatom with the atom immediately adjacent the 11-carbon atom being carbon, R2 is a hydro... | 10/15/1985 |
| 4519949 | Steroid-20-carboxylic acid compounds and a process for their production New ÆŠ1,4,9(11)-pregnatrien-3-one-2o-carboxlic acid compounds are described, corresponding to general formula I below: ##STR1## in which X represents halogen, particularly chlorine or bromine or NH2. There is also described the process for... | 05/28/1985 |
| 4515787 | Steroids Novel 9,11ଲ-dichloro-16-methyl-ÆŠ1,4 -pregnadiene 3,20-diones of the formula ##STR1## wherein R is selected from the group consisting of trimethylsilylphenyl, cyclododecyloxy, dicyclopentylmethoxy and cyclohexylmethoxy ... | 05/07/1985 |
| 4477445 | 3-Keto-19-nor-ÆŠ4,9-steroids Novel 3-keto-19-nor-ÆŠ4,9-steroids of the formula ##STR1##... | 10/16/1984 |
| 4472392 | Sulfonate containing ester prodrugs of corticosteroids Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1## and their salts.... | 09/18/1984 |
| 4469689 | Sulfonate containing ester prodrugs of corticosteroids Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1## and their salts.... | 09/04/1984 |
| 4464302 | 17-[(Hydroxymethyl)formamido-methylene]-steroids Novel 17-[(hydroxymethyl)formamido methylene]-steroids of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted with halogen or an oxygen or nitrogen function... | 08/07/1984 |
| 4456602 | Amine containing ester prodrugs of corticosteroids Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1##... | 06/26/1984 |
| 4447424 | Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the... | 05/08/1984 |
| 4443440 | Amine containing ester prodrugs of corticosteroids Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1##... | 04/17/1984 |
| 4440684 | Process for the preparation of 6-methyl-ÆŠ4,6 -3-keto steroids A process for preparing 6-methyl-ÆŠ4,6 -3-keto steroids of the formula ##STR1## comprises reacting a corresponding ÆŠ4 -3-keto steroid with methoxymethyl acetate (CH3 --O--CH2 --OAc) in an inert solvent ... | 04/03/1984 |
