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|6080878||Method of preparing 16-dehydro vitamin D compounds|
The invention relates to a new method of preparing 16-dehydro vitamin D compounds having formula I ##STR1## wherein: R has the epi-configuration or the normal configuration and represents straight or branched C1-6 -alkyl, C2-6 -...
|6030962||Vitamin D3 analogs with bis C-20 side chains|
This invention provides Vitamin D3 analogs of the Formula I ##STR1## wherein: X is H2 or CH2 ; Y is hydrogen, hydroxy or fluorine; Z is hydroxy; R1 and R2 are a (C1 -C4) alkyl or fluo...
|5756489||18,19-dinor-vitamin D compounds|
18,19-dinor-vitamin D3 analogs in which the angular methyl group attached to carbon 13 of the CD-ring and the exocyclic methylene group attached to carbon 10 of the A-ring have been removed and replaced by a hydrogen atom. The 18,19-dinor vitam...
|5710293||Method of preparation of ester derivatives of steroids|
The present invention relates to a method of using a perchloric acid catalyzed reaction to make acyl derivatives of norprogesterone compounds and, in particular, 16-methylene-17-hydroxy-19-norpregn-4-ene-3,20-dione....
|5599806||Hydrazino and hydroxyamino-14-ଲ-hydroxyandrostane derivatives active on the cardiovascular system processes for their preparation and pharmaceutical compositions containing same|
The invention describes hydrazino and hydroxyamino-14ଲ-hydroxyandrostane derivatives having general formula (I): ##STR1## wherein the symbol means or ଲ configuration and A, B, R1, R2, R3, and...
|5583127||17-iminomethylalkenyl-5 ଲ, 14 ଲ-androstane and 17-iminoalkyl-5 ଲ, 14 ଲ-androstane derivatives active on the cardiovascular system, and pharmaceutical compositions containing same|
Disclosed are 17-iminomethylalkenyl and 17-iminoalkyl-14ଲ-hydroxy-5ଲ-androstane derivatives of the formula (I): ##STR1## wherein the symbol means or ଲ configuration or a Z or E configuration; A represents (CH2
|5444055||17-hydroxyiminomethyl-5-ଲ, 14 ଲ-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same|
17-hydroxyiminomethyl-14ଲ-hydroxy-5ଲ androstane derivatives, active on the cardiovascular system, a process for their preparation and pharmaceutical compositions thereof having the general formula ##STR1##...
|5352808||Process for steroid preparation|
A process for the preparation of a compound of the formula ##STR1## wherein R1 is selected from the group consisting of hydrogen, alkyl of 1 to 4 carbon atoms optionally substituted by halogen or a nitrogen or oxygen function and alkenyl a...
A process for the preparation of novel 14, 17-dihydroxy-17ଲ-substituted steroids by reacting 14-hydroxy-17-oxo-steroids with metal organic compounds and the use of the said novel steroids in the production of 14, 17&...
|5028722||Novel 7 ଲ-hydroxy-4-pregnene-3,20-dione derivatives and method for preparing same|
Novel 7ଲ-hydroxy-4-pregnene-3,20-dione derivatives are disclosed. The group of these compounds has possibility of being utilized as an intermediate for the synthesis of progesterone derivatives having ovulation-inhibiting activity. These compounds themse...
|4584289||14-aminosteroid derivatives, application in therapy and process of preparation|
The present invention relates to new 14-aminosteroids and their application in therapy and also to a process for their preparation....
|4469689||Sulfonate containing ester prodrugs of corticosteroids|
Novel solution stable ester prodrugs of corticosteroids of the formula ##STR1## and their salts....
|3962217||Process for the manufacture of Ɗ16 -steroid-14ଲ,18,20-triols and -14ଲ,20-diol-18-ols of the pregnane series|
The invention is for a selective reduction of the 20- oxo group in Ɗ16 -steroid-14ଲ,18-diol-20-ones of the pregnane series to form the two epimeric 20-alcohols having the 20 S and 20 R configuration. The process is especially intended fo...
|3939187||15,-Sulfonyloxy-12ଲ-hydroxypregnanes and process for the preparation thereof|
15-Sulfonyl-12ଲ-hydroxypregnanes of the formula ##SPC1## Wherein Ac is lower-acyl and R is alkyl, cycloalkyl, aralkyl or aryl, which are useful as intermediates for the production of digoxigenin, are produced by the selective sulfonic acid es...