Famous Patents
The ice cream cone was invented at the St. Louis Worlds Fair by Ernest Hamwi in 1904. His waffle booth was next to an ice cream vendor who ran short of dishes. Hamwi rolled a waffle to hold ice cream and the cone was born.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7381566 | Method for preparing organic nanotubules of lithocholic acid, nanotubules derived therefrom, and uses thereof A method for preparing organic nanotubules in an aqueous medium including preparing a basic solution with a pH from 10 to 14, adding an organic compound of the formula: wherein R1 is a C17-C20 | 06/03/2008 |
| 7122533 | Cosalane compounds and methods for their use The present invention relates to methods, compounds and compositions for inhibiting effective binding of a chemokine to its cellular receptor. In one form of the invention, a method includes contacting a cellular population with an effective amount of cosalane or an... | 10/17/2006 |
| 6900192 | Bile-acid conjugates for providing sustained systemic concentrations of drugs This invention is directed to compounds that provide for sustained systemic concentrations of therapeutic or prophylactic agents following administration to animals. This invention is also directed to pharmaceutical compositions including and methods using such comp... | 05/31/2005 |
| 6881730 | Steroid compounds with a c17-alkyl side chain and an aromatic a-ring for use in therapy Compounds of Formula (I) in which: R1 and R2, which may be the same or different, each represents a lower alkyl, alkenyl or alkynyl group; R3 represents a methyl group having α- or β-configuration; R4 represents a hydrog... | 04/19/2005 |
| 6770414 | Additive for photoresist composition for resist flow process The present invention provides an additive for a photoresist composition for a resist flow process. A compound of following Formula 1 having low glass transition temperature is added to a photoresist composition containing a polymer which is not suitable for the res... | 08/03/2004 |
| 6706701 | 6, 7-oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 03/16/2004 |
| 6653492 | Preparation of bile acids Certain bile acids find use in the pharmaceutical industry. In view of the wide distribution of serious diseases such as HIV, AIDS and Bovine Spongiform Encephalopathy (BSE) it is desirable to avoid--as far as practicable--to have any components of animal... | 11/25/2003 |
| 6635774 | Preparation of sterol and stanol-esters The present invention provides a method for the direct esterification of stanols and sterols with fatty acids to form stanol/sterol-esters. The method provides a synthetic route that is amenable to large scale production of the esters in high yields. A pr... | 10/21/2003 |
| 6624156 | Methods of making and method of using hybrid cholinergic agents and compositions The present invention provides hybrid molecules and methods of synthesizing such hybrid molecules from a cholinergic agent and a bile acid. The hybrid molecules function as cholinergic agents and may be either cholinergic agonists or cholinergic antagonis... | 09/23/2003 |
| 6624155 | Hybrid cholinergic agents and compositions The present invention provides hybrid molecules and methods of synthesizing such hybrid molecules from a cholinergic agent and a bile acid. The hybrid molecules function as cholinergic agents and may be either cholinergic agonists or cholinergic antagonis... | 09/23/2003 |
| 6528501 | 22s-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity ##STR1## The invention relates to 22S hydroxycholesta-8, 14-diene derivatives having general formula (I) wherein R1 is OR, OSO3 H or --NOR; with R being H, (C1-6)alkyl or (C1-6)acyl; each of R2 and R | 03/04/2003 |
| 6497987 | Photosensitive lithocholate derivative and chemically amplified photoresist composition containing the same A photosensitive compound, and a chemically amplified photoresist composition containing the photosensitive compound, maintain transparency even when exposed to a short-wavelength light source of 193 nm or below, and exhibit improved adhesion to an underl... | 12/24/2002 |
| 6437156 | 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function The invention relates to a method of altering hypothalamic function in an individual. The method comprises nasally administering a human vomeropherin, e.g. a 19-nor cholane steroid, or a pharmaceutical composition containing a vomeropherin, such that the ... | 08/20/2002 |
| 6388108 | Aminosterol compounds and uses thereof Newly isolated aminosterol compounds and pharmaceutical compositions based on the aminosterol compounds are described. Methods for the treatment of various disorders, for example, a microbial infection, are also described.... | 05/14/2002 |
| 6177420 | 20-aralkyl-5-pregnane derivatives The invention relates to 20-aralkyl-5-pregnane derivative having general formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 is (H,OR), (H,OSO3 H) or NOR; R is H, (C1-6)alkyl or (C1-6)a... | 01/23/2001 |
| 6080735 | Estra-1,3,5(10)-trien derivatives, processes for their preparation and pharmaceutical compositions containing these compounds This invention is relating to new estra-1,3,5(10)-trien-sulfamates carrying at the 3-position an R--SO2 --O--group, with R being an R1 R2 N--group in which R1 and R2, independently of each other, repr... | 06/27/2000 |
| 6046186 | Estrone sulfamate inhibitors of estrone sulfatase, and associated pharmaceutical compositions and methods of use Novel compounds useful as inhibitors of estrone sulfatase are provided. The compounds have the structural formula (I) wherein r1 is an optional double bond, R1 and R2 are selected from the group consisting of hydrogen and lower alky,... | 04/04/2000 |
| 6040468 | Method of preparing 16, 17-dialkylated steroids 16, 17-dialkylated steroids are prepared by reacting a 16-alkyl-17(20)-enyl-20-silyl ether with an alkylating agent and an enol silyl ether cleaving agent in a suitable solvent.... | 03/21/2000 |
| 5847173 | 21-nor-vitamin D compounds 21-norvitamin D3 analogs in which the methyl group normally attached to the side chain at carbon 20 has been replaced by a hydrogen atom. The compounds are characterized by a marked intestinal calcium transport activity while exhibiting much lo... | 12/08/1998 |
| 5792759 | 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl cyclopentaneperhydrophenanthrene derivatives active on the cardiovascular system, a process for their preparation and pharmaceutical compositions containing the same Novel 17-hydroxyiminoalkyl and 17-hydroxyiminomethylalkenyl steroids of the general formula (I) ##STR1## where A, R1 and R2 are defined in the specification are disclosed. The compounds have cardiovascular activity. Pharmaceutic... | 08/11/1998 |
| 5723455 | Antiandrogenic agents and related pharmaceutical compositions and methods of use Novel antiandrogenic agents are provided. An exemplary group of compounds has the structural formula (I) ##STR1## wherein R1 through R10, a and b are as defined herein. Pharmaceutical compositions and methods for using the compo... | 03/03/1998 |
| 5705495 | Sulfamate derivatives of 1,3,5(10)-estratriene derivatives, methods for their production and pharmaceuticals containing these compounds The invention relates to new sulfamate derivatives of 1,3,5(10)-estratriene derivatives of the general formula I ##STR1## wherein the 3-sulfamate moiety is acylated, sulfonated or amidosulfonated. Furthermore, methods for the production of the compou... | 01/06/1998 |
| 5637691 | Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants Compounds having a broad range of antimicrobial activity generally have a structure including asteroid nucleus with a cationic, preferably polyamine, side chain (X) and an anionic side chain (Y). The invention is also directed to compounds of the Formula ... | 06/10/1997 |
| 5618806 | 17 and 17ଲ-substituted estra-1,3,5(10)-triene-3-carbboxlic acid Invented are 17 and 17ଲ-substituted acyl-3-carboxy aromatic A ring analogues of steroidal synthetic compounds. Representative of such compounds include the following ##STR1## wherein Z is or ଲ ##STR2## in which A ... | 04/08/1997 |
| 5561124 | 17--acyl steroids which inhibit 5--reductase The invention relates to substituted 17-acyl steroidal 5-reductase inhibiting compounds. The invention also relates to pharmaceutical compositions containing these compounds and their use for reducing prostate size and treating prostate aden... | 10/01/1996 |
| 5559258 | Ethylenically unsaturated bile acid derivatives, processes for their preparation and precursors Ethylenically unsaturated bile acid derivatives of the formula I G--X--A I in which G, X and A have the meanings indicated, are described. They are suitable for the preparation of polymeric bile acid derivatives. B... | 09/24/1996 |
| 5541348 | Bile acids for biological and chemical applications and processes for the production thereof Novel bile acids according to the general formula ##STR1## wherein R1 represents a hydroxyl group, R2 and R3 both represent a hydrogen or a hydroxyl group, or R2 represents a hydroxyl group or a ଲ hyd... | 07/30/1996 |
| 5523428 | Process for the production of 1-methyl-3-keto-Ɗ1,4 steroids A process for the production of 1-methyl-3-keto-Ɗ1,4 steroids of general formula I ##STR1## in which St symbolizes the radical of asteroid molecule, where a 3-keto-Ɗ1,4 steroid of general formula II ##STR2## in which... | 06/04/1996 |
| 5496813 | Spontaneously dispersible concentrates and aqueous microemulsions with steryl retinates having anti-tumor activity There are described spontaneously dispersible agents containing sterolester and/or sterolphosphor compounds having a pronounced antitumour activity. Novel sterolesters and sterolphosphor compounds, their use for treating tumors, and processes for their pr... | 03/05/1996 |
| 5473087 | Preparation process for 20-keto 21(S) hydroxy steroids compounds and intermediates Mixtures of compounds of ##STR1## or a mixture of the latter and a compound of the formula ##STR2## which are useful intermediates for the preparation 20-keto-21(S)-hydroxy steroids.... | 12/05/1995 |
| 5399685 | Process for the preparation of 20-keto-21 alpha-01-steroids A process for the preparation of a compound of the formula ##STR1## wherein R1 is alkyl of 1 to 3 carbon atoms, R2 is alkyl of 1 to 12 carbon atoms, R3 is alkyl of 1 to 4 carbon atoms comprising reacting a compound of... | 03/21/1995 |
| 5384419 | Preparation process for 20-keto-21(S) hydroxy steroid compounds and intermediates An improved process for the preparation of 20-keto-21(S)-hydroxy steroids of the Formula ##STR1## wherein R1 is alkyl of 1 to 3 carbon atoms, R2 is alkyl of 1 to 12 carbon atoms, and R3 is alkyl of 1 to 4 carbon atoms... | 01/24/1995 |
| 5352781 | Process for precursors to calcitriol and related compounds The process of the invention comprises reacting a C-22-halo-23,24-bisnorsteroid or C-22-halo-23,24-bisnor-9,10-secosteroid with a nickel complex of an electron withdrawing alkene of the formula ##STR1## wherein R1 is hydrogen, hydroxycarbo... | 10/04/1994 |
| 5319115 | Method for making 3-hydroxy, 3ଲ-substituted-pregnanes This invention provides a simplified method for converting pregnan-3,20-dione compounds to 3-hydroxy,3ଲ-substituted-pregnanes. By selective use of reagents the unprotected dione is converted chemoselectively and diastereoselectively into... | 06/07/1994 |
| 5272140 | 11-aryl steroid derivatives The invention relates to 11-aryl steroid derivatives, having the structure ##STR1## wherein: R1, R2, R3, and R4 are as described in the specification and to processes for their preparation and to pharmaceutical... | 12/21/1993 |
| 5140106 | Process for the production of 3-deoxy-4-ene steroids A process for the production of 3-deoxy-4-ene steroids of the general formula I ##STR1## is described, in which R1, R2 and R3 mean a hydrogen atom or a methyl group, R4 represents a lower alkyl group, a phe... | 08/18/1992 |
| 5120724 | Aldosterone biosynthesis inhibitor Aldosterone biosynthesis inhibitors having substantially no intrinsic antiandrogenic activity are disclosed as well as pharmaceutical compositions containing such compounds and methods of treatment utilizing these compositions.... | 06/09/1992 |
| 5086047 | Novel steroids A compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl, alkylthio and haloalkyl of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms, option... | 02/04/1992 |
| 5064822 | Novel 3-keto-19-nor-Ɗ4,9 -steroids Novel 3-keto-19-nor-Ɗ4,9 -steroids of the formula ##STR1## wherein R1 is selected from the group consisting of naphthyl, phenylphenyl, alkyl of 1 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms optionally containing additiona... | 11/12/1991 |
| 5041433 | 11-keto or hydroxy 3,5-diene steroids as inhibitors of steriod 5--reductase Invented are carboxyl and carboxyl alkyl ester substituted 11-keto and hydroxy analogues of synthetic steroidal compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds to inhibit steroid 5--reductase.... | 08/20/1991 |
