Class 552/519 - Oxygen bonded directly to the nitrogen (e.g., oximes, isonitrosos, etc.)

Subclass of Class 552 - Organic compounds -- part of the class 532-570 series
Definition: Compounds wherein oxygen is bonded directly to the nitrogen.
No. of patents: 34
Last issue date: 12/04/2007

Number	Title	Issue Date
7304171	Compounds and methods for cytoprotection Compounds, compositions and methods for treating degenerative diseases and disorders are disclosed, the compounds having the following structure (I): including stereoisomers, prodrugs and pharmaceutically accepta...	12/04/2007
7135581	Antiangiogenic agents Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in th...	11/14/2006
6995278	Antiangiogenic agents Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the spec...	02/07/2006
6852710	2-alkoxyestradiol analogs with antiproliferative and antimitotic activity The application discloses novel 2-alkoxyestradiol analogs which exhibit anti-proliferative properties, and methods of making and using such compounds to inhibit undesired cell proliferation and tumor growth. Additionally, methods are disclosed of treating diseases a...	02/08/2005
6670353	Oxime-group containing oestrone sulphatase inhibitors A sulphamate compound suitable for use as an inhibitor of oestrone sulphatase (E.C.3.1.6.2) is described. The compound is a polycyclic compound comprising at least two ring components, wherein the polycyclic compound comprises at least one sulphamate grou...	12/30/2003
6596885	19-Nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, their use as medicaments and compositions Novel compounds having a formula selected from the group consisting of ##STR1## wherein the substituents are defined as in the specification which are intermediates for the production of vinyl compounds having a remarkable anti-estrogenic and anti-prolife...	07/22/2003
6579864	3-methylene steroid derivatives The invention concerns a 3-methylene steroid derivative having general formula (1) wherein R1 is H or together with R3 forms a ଲ-epoxide or R1 is absent if there is a 5-10 or 4-5 double bond; R2 is (C...	06/17/2003
6518262	22R-hydroxycholesta-8, 14-diene derivatives for the inhibition of meiosis The invention relates to 22R-hydroxycholesta-8,14-diene derivatives having general formula (I) wherein R1 is OR, OS03 H or .dbd.NOR; with R being H, (C1-6)alkyl or (C1-6)acyl; each of R2 and R3 ...	02/11/2003
6303589	Pentacyclic triterpenes The present invention relates to fungicidally effective compositions containing at least one pentacyclic triterpene compound....	10/16/2001
6262282	17ଲ-allyloxy(thio)alkyl-androstane derivatives for the modulation of meiosis The invention relates to 17ଲ-allyloxy(thio)alkyl-androstane derivatives having general formula (I) wherein R1 is (H, OR), (H, OSO3 H) or NOR; with R being H, (C1-6)alkyl or (C1-6)acyl; each of R2	07/17/2001
6180803	19-nor-pregnene derivatives and pharmaceuticals containing such derivatives The invention relates to compounds of the formula: ##STR1## in which R1, R2, R3, R4, R5, R6, n and X are as defined in the specification, and to pharmaceutical compositions containing them....	01/30/2001
6177420	20-aralkyl-5଱-pregnane derivatives The invention relates to 20-aralkyl-5଱-pregnane derivative having general formula (I), or a pharmaceutically acceptable salt thereof, wherein R1 is (H,OR), (H,OSO3 H) or NOR; R is H, (C1-6)alkyl or (C1-6)a...	01/23/2001
6136992	2-alkoxy estradiols and derivatives thereof Compounds represented by the following structural formula: ##STR1## wherein R1, R2 and R3 are as defined in the specification. The compounds are disclosed as useful in the treatment of various forms of cancer....	10/24/2000
5194602	9଱-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids New 9଱-hydroxy-17-methylene steroids are prepared by the introduction of a substituted 17-methylene group in 9଱-hydroxyandrost-4-ene-3, 17-dione. The resulting compounds are useful starting compounds in the synthesis of corticosteroids....	03/16/1993
5182381	Intermediates for 3-keto-19-nor-Ɗ⁴,9 -steroids Novel 3-keto-19-nor-Ɗ4,9 -steroids of the formula ##STR1## and their non-toxic, pharmaceutically acceptable acid addition salts possessing a remarkable antiglucocorticoidal activity....	01/26/1993
5162312	11ଲ-substituted 16଱, 17଱-methylene-estra-4,9-dien-3-ones 11ଲ-substituted-16଱, 17଱-methylene-estra-4,9-dien-3-ones of formula I ##STR1## wherein R1 is a methyl or ethyl group; R2 is H; a C1-6 -alkyl, -alkoxymethyl, -alkanoyl or -alkoxcarbonyl group ; 2-meth...	11/10/1992
5132299	11ଲ-phenyl-4,9,15-estratrienes, their manufacture and pharmaceutical preparations containing same New 11ଲ phenyl-4,9,15-estratrienes of formula I ##STR1## are described, where X implies an oxygen atom or a hydroxyimino grouping N~OH, R1 stands for a hydrogen atom or a methyl group, R2 implies a hydrogen atom, an alkyl radic...	07/21/1992
5086047	Novel steroids A compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl, alkylthio and haloalkyl of 1 to 6 carbon atoms, alkenyl and alkynyl of 2 to 6 carbon atoms, option...	02/04/1992
5034548	Steroid derivatives useful as hypocholesterolemics Lanosterols substituted in the 14 and/or 15 position(s) which are active in inhibiting lanosta-8,24-dien-3ଲ-ol 14଱-methyl-demethylase activity, suppressing 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR) activity, decreasing cholesterol...	07/23/1991
4753932	Novel 10-substituted steroids A novel steroid of the formula ##STR1## wherein X is methylene and R is an optionally substituted carbocyclic aryl or heterocyclic aryl or optionally substituted vinyl or ethynyl or X is a simple bond or --S-- and R is optionally substituted carbocyc...	06/28/1988
4634695	Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the...	01/06/1987
4591461	Preparation of tri-cyclo nitriles A novel process for the preparation of a 16-imino-17-aza-steroid of the formula ##STR1## wherein A is selected from the group consisting of hydrogen and tritium comprising reacting a compound of the formula ##STR2## wherein A has the above ...	05/27/1986
4519946	Steroids Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbons atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with th...	05/28/1985
4515786	11଱-Amino-androstanes R3 is a C1-6 alkyl group or a C3-7 cycloalkyl group; and R4 is a group --OR5 or --OCOR6 where R5 is an optionally substituted alkyl or alkenyl group which may contain up to 6 carbon atoms,...	05/07/1985
4497805	11଱-amino-androstanes Compounds of the formula ##STR1## wherein R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group; R2 is a C1-6 alkyl group or a C3-7 cycloalkyl group; R3 is a hydroxy group or a gro...	02/05/1985
4447424	Steroid derivatives Novel 19-nor steroids and 19-nor-D-homo-steroids of the formula ##STR1## wherein R1 is an organic radical of 1 to 18 carbon atoms containing at least one atom selected from the group consisting of nitrogen, phosphorous and silicon with the...	05/08/1984
4353898	11଱-Amino-androstanes Compounds of formula ##STR1## wherein: R1 is a C1-8 alkyl group or a C3-7 cycloalkyl group; R2 is a hydrogen atom, a C1-6 alkoxy group or a C2-5 alkanoyloxy group; and R is a C1-8...	10/12/1982
4352798	11 ଱-Amino-androstanes Compounds of formula ##STR1## (wherein): R1 is a hydrogen atom, a C1-8 alkyl group or a C3-7 cycloalkyl group; and R2 is a hydrogen atom, a C1-6 alkyl group or a C3-6 cycloalkyl group;...	10/05/1982
4297350	Male contraceptive steroids and methods of use The steroids of the present invention have been found to be useful as male contraceptives when administered orally. Upon cessation of administration of the male contraceptive steroids of the present invention the male promptly regains normal fertility....	10/27/1981
4220775	Preparation of 4-aza-17-substituted-5଱-androstan-3-ones useful as 5଱-reductase inhibitors A method of preparing a compound of the formula: ##STR1## where Formula (I) may also have the structure of partial Formula (III); wherein, ##STR2## R' is hydrogen or methyl; R" is hydrogen or ଲ-methyl; R'" is ଲ-methyl or hydroxy; Z i...	09/02/1980
4197296	Androstanes Steroids of the androstane series are described which possess a 3଱-hydroxy group, a 5଱- or 5ଲ- hydrogen atom, a 10- methyl group, an 11଱- substituted amino group. The 17-position may be unsubstituted or substituted by a methyl or e...	04/08/1980
3988356	Novel haptenes and antigens Novel haptenes of the formula ##SPC1## Wherein when X is hydrogen, Y is =N-O-(CH2)a --COOH and a is a whole number of 1 to 12 and when ##EQU1## X is hemiterephthaloyloxy in the ଱- or ଲ-position and antigens prep...	10/26/1976
3975413	Novel haptenes and antigens Novel haptenes of the formula ##SPC1## Wherein X is ##EQU1## when Y is ##EQU2## in the ଱- or ଲ-position and R' is selected from the group of p-phenylene and --(CH2)a --and a is a whole number from 1 to 18 ...	08/17/1976
3935245	Radioactively labeled steroid derivatives Steroids bearing the substituent --X-NR1 R2 wherein --NR1 R2 is a tritium of carbon-14 labeled amino or amino-acid group and --X-- is --R3 --, --OCOR3 --, =N--O--R3 -- or --NHCOR...	01/27/1976

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Class 552/519 - Oxygen bonded directly to the nitrogen (e.g., oximes, isonitrosos, etc.)