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...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 7304171 | Compounds and methods for cytoprotection Compounds, compositions and methods for treating degenerative diseases and disorders are disclosed, the compounds having the following structure (I): including stereoisomers, prodrugs and pharmaceutically accepta... | 12/04/2007 |
| 7135581 | Antiangiogenic agents Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in th... | 11/14/2006 |
| 6995278 | Antiangiogenic agents Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in the spec... | 02/07/2006 |
| 6852710 | 2-alkoxyestradiol analogs with antiproliferative and antimitotic activity The application discloses novel 2-alkoxyestradiol analogs which exhibit anti-proliferative properties, and methods of making and using such compounds to inhibit undesired cell proliferation and tumor growth. Additionally, methods are disclosed of treating diseases a... | 02/08/2005 |
| 6596885 | 19-Nor steroids having a thiocarbonated chain in position 11beta, their preparation process and the intermediates of this process, their use as medicaments and compositions Novel compounds having a formula selected from the group consisting of ##STR1## wherein the substituents are defined as in the specification which are intermediates for the production of vinyl compounds having a remarkable anti-estrogenic and anti-prolife... | 07/22/2003 |
| 6500815 | Substituted 11.beta steroid derivatives, method for preparing same and intermediates of said method, use as medicine and compositions containing them The invention concerns compounds of formula (I) wherein: X, Y, R1, R2, Z, G are as defined in the description, the methods for preparing them and the intermediates in said method, their use as medicine and the pharmaceutical composit... | 12/31/2002 |
| 6136992 | 2-alkoxy estradiols and derivatives thereof Compounds represented by the following structural formula: ##STR1## wherein R1, R2 and R3 are as defined in the specification. The compounds are disclosed as useful in the treatment of various forms of cancer.... | 10/24/2000 |
| 5723638 | Process for 20-oxo-17,21-diol steroids The invention is drawn to a process for the preparation of a steroid of the formula ##STR1## wherein R1 is hydrogen or alkyl of 1 to 4 carbon atoms, R2 is alkyl of 1 to 4 carbon atoms and theo A, B, C, and D ring system has at ... | 03/03/1998 |
| 5721299 | Electrically conductive and abrasion/scratch resistant polymeric materials, method of fabrication thereof and uses thereof Electrically conductive and abrasion resistant polymeric compositions, methods of fabrication thereof and uses thereof are described. Admixtures of abrasion resistant materials and electrically conductive polymeric materials are formed. Many of these admi... | 02/24/1998 |
| 5444055 | 17-hydroxyiminomethyl-5-ଲ, 14 ଲ-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same 17-hydroxyiminomethyl-14ଲ-hydroxy-5ଲ androstane derivatives, active on the cardiovascular system, a process for their preparation and pharmaceutical compositions thereof having the general formula ##STR1##... | 08/22/1995 |
| 4499020 | Mixed anhydrides and processes thereof Mixed anhydrides products are described. These mixed anhydrides are produced by reaction of a carboxylic acid-containing steroid with a material having the formula: ##STR1## wherein: X is a halogen Z is an oxygen or sulfur R is a hydrocarbon in an in... | 02/12/1985 |
| 4425273 | Process for production of chenodeoxycholic acid A process for producing chenodeoxycholic acid of the following formula ##STR1## which comprises reducing a 12-oxocholanic acid tosylhydrazone compound of the following formula ##STR2## wherein R1 and R2 are identical or dif... | 01/10/1984 |
| 4333928 | 16 -Alkyl steroids, their preparation, and pharmaceutical preparations thereof 16 -Alkyl steroids of the formula ##STR1## wherein R1 is hydrogen or methyl, R2 is hydrogen, alkyl, acyl, or glycosyl R3 is hydrogen or a substituted or unsubstituted, saturated or unsaturated lower hydrocarbon resi... | 06/08/1982 |
| 4248783 | Steroids having a 3-(4-hydroxyphenyl)pentanedioic acid monohydrazide substituent Steroids having as a substituent a group having the formula ##STR1## wherein R is hydrogen or alkyl and n is 0, 1, 2, 3 or 4 are useful as haptens and are also useful when radioiodinated as tracers in radioimmunoassays.... | 02/03/1981 |
| 4189477 | Novel Ɗ4 -pregnenes Novel Ɗ4 -pregnenes of the formula ##STR1## wherein X1 is selected from the group consisting of .dbd.O and ##STR2## Y is selected from the group consisting of hydrogen and halogen, R1 is selected from the group ... | 02/19/1980 |
| 4116985 | Novel method for preparing cholesta-5,7-diene 3ଲ,25-diol and derivatives thereof A new method for synthesizing cholesta-5,7-diene-3ଲ,-25-diol and cholesta-5,7-diene-1,3ଲ,25-triol has been discovered. ##STR1## wherein R is hydrogen or hydroxy. Various intermediates and reaction steps are claimed.... | 09/26/1978 |
| 4110326 | Acylated diepoxy-androstane and a process for the preparation thereof A compound of the formula (I) ##STR1## wherein X is a halogen, Z1 and Z2 are both hydrogen, or Z1 is hydroxy and Z2 is chlorine, or Z1 and Z2 together stand for an -epoxy group.... | 08/29/1978 |
| 4075233 | 16-Dehydro steroids of the androstane series Therapeutically useful 16-dehydro-androstane derivatives of the general formula: ##STR1## processes for their preparation and pharmaceutical compositions for the treatment of dermatological disorders, which contain as active ingredient at least ... | 02/21/1978 |
| 4071515 | Triamino-androstanes and a process for the preparation of the said compounds New triamino-androstanes with curare-type properties and a process for the preparation thereof are disclosed.... | 01/31/1978 |
| 4016269 | 17-HYDROXY-1,3,5(10),15-ESTRATETRAENES AND PROCESS FOR THEIR PRODUCTION Novel estrogenic 17-hydroxy-1,3,5(10),15-estratetraenes of the formula ##STR1## wherein R1 is H, lower alkyl or lower acyl, R2 is lower alkyl and R3 is H, lower alkyl, lower acyl or tetrahydropyranyloxy, are ... | 04/05/1977 |
| 3966777 | Process for the production of 1-hydroxy provitamin D3 and 1-hydroxy vitamin D3 A process for the production of 1-hydroxy provitamin D3 which comprises treating 1, 2-epoxy-cholesta-4,6-diene-3-one at a low temperature with liquid ammonia; with ammonium chloride and with lithium metal to produce 1³... | 06/29/1976 |
