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Class 552/514 - The additional ring shares the 16,17-positions of the cyclopentanohydrophenanthrene ring system


Subclass of Class 552 - Organic compounds -- part of the class 532-570 series
Definition: Compounds in which the additional ring is ortho-fused to
No. of patents: 26
Last issue date: 09/27/2005


NumberTitleIssue Date
694953114 β, 16, 17-methylene steroids as novel androgens
Disclosed are androgenic steroids of the (14β,17α)-17-(hydroxymethyl) type. The invention relates to an improvement thereof, which is based on the presence of a β-oriented, annellated cyclopropyl group which includes carbon atoms 16 and 17 of the steroid skeleton...
09/27/2005
6313180Steroid compounds having contraceptive and anti-osteoporosis activity
The invention relates to a steroid compound having the formula (I) ##STR1## comprising a ring E, said ring sharing carbon atoms at position 16 and 17 with the five-membered ring D and being ଱ with respect to said D-ring. In addition, the carbon atom...
11/06/2001
6077873Steroid compounds having contraceptive and anti-osteoporosis activity
The invention relates to a steroid compound having the formula (I) ##STR1## comprising a ring E, said ring sharing carbon atoms at position 16 and 17 with the five-membered ring D and being ଱ with respect to said D-ring. In addition, the carbon...
06/20/2000
5703066Progestationally active 19,11-bridged 4-estrenes
In this invention, the new etheno- and ethano-19,11-bridged 4-estrenes of general formula I ##STR1## are described, in which W, R1, R2, R6a, R6b, R7, R14, R15, R16
12/30/1997
5631249Estrogen nucleus derivatives for use in the inhibition of sex steroid activity
Novel compounds for the inhibition of sex steroid activity for the treatment of both androgen-related and estrogen-related diseases include for example 15- and 16-halo substituted compounds such as: ##STR1## The compounds are characterized by an estr...
05/20/1997
540792811ଲ-aryl-gona-4,9-dien-3-ones
This invention relates to 11ଲ-aryl-gona-4,9-dienes of the general formula I ##STR1## wherein the variables are defined in the specification. The compounds are progesterone antagonists and are suitable for inducing labor or an abortion....
04/18/1995
5240814Curable, heat activatable transfer toners
A non-electroscopic prolonged tack toner for transferring toned images to an image receptor at low temperatures with improved back transfer characteristics....
08/31/1993
516619911ଲ-aryl-16଱,17଱-cyclohexano-estra-4,9-dienes
11.sym.-Aryl-16଱,17଱-cyclohexano-estra-4,9-dienes of formula ##STR1## wherein R1 is H or a methyl group; R2 is --OCH3, --SCH3, --N(CH3)2, --NHCH3, --CN, --CHO, --COCH...
11/24/1992
516231211ଲ-substituted 16଱, 17଱-methylene-estra-4,9-dien-3-ones
11ଲ-substituted-16଱, 17଱-methylene-estra-4,9-dien-3-ones of formula I ##STR1## wherein R1 is a methyl or ethyl group; R2 is H; a C1-6 -alkyl, -alkoxymethyl, -alkanoyl or -alkoxcarbonyl group ; 2-meth...
11/10/1992
507354811 ଲ-substituted progesterone analogs
A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5 , wherein R5 is C2...
12/17/1991
495449011 ଲ-substituted progesterone analogs
A 11ଲ-aryl-19-norprogesterone steroid of the formula: ##STR1## wherein (i) R1 is H, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, OH, OC(O)CH3, or OC(O)R5, wherein R5 is C2-...
09/04/1990
453640111ଲ-aryl estradienes, processes for their production and pharmaceutical preparations containing them
Compounds of the formula I ##STR1## wherein R1 is ##STR2## wherein RI and RII each independently is alkyl of 1-4 carbon atoms, or RI and RII together with the connecting N-atom form a 5...
08/20/1985
4474702[16,17-a]Cyclopentano pregnenes
Antiinflammatory activity is exhibited by pregnenes having the structural formula ##STR1## wherein R1 is hydrogen, hydroxy, halogen, or acyloxy; R2 and R3 are each hydrogen, R2 and R3 are each methyl,...
10/02/1984
4447426Steroid monohydrates, formulations containing same and method
A monohydrate of a steroid having the structure ##STR1## and the 1,2-dehydro derivatives thereof, is provided which monohydrate is in the form of a particulate material having a stable average particle size of less than about 20 microns. Cream and lo...
05/08/1984
4391755Steroid monohydrates, formulations containing same and method
A monohydrate of a steroid having the structure ##STR1## and the 1,2-dehydro derivatives thereof, is provided which monohydrate is in the form of a particulate material having a stable average particle size of less than about 20 microns. Cream and lo...
07/05/1983
4322349Process for preparing 6-methylene steroids
A process for preparing a 6-methylene-Ɗ4 -3-keto steroid of the formula ##STR1## wherein R is hydrogen, alkoxy of up to 6 carbon atoms or acyloxy of up to 6 carbon atoms wherein the acyl group is that of a carboxylic acid, and R' is the C...
03/30/1982
4219488Process for preparing steroidal [16଱,17-b]naphthaleno-21-carboxylic acid esters
Steroidal [16଱,17-b]naphthaleno-21-carboxylic acid esters can be prepared from 21-hydroxy-Ɗ16 -steroids by converting the starting steroid to a 21-carboxylic acid ester -Ɗ16 -steroid and then fusing the tetrahydronaphthalene ...
08/26/1980
4213912Process for preparing steroidal [16଱,17-d]cyclohexene-21-carboxylic acid esters
Steroidal [16଱, 17-d]cyclohexene-21-carboxylic acid esters can be prepared from 21-hydroxy-Ɗ16 -steroids by first converting the starting steroid to a 21-carboxylic acid ester -Ɗ16 -steroid and then fusing the cyclohexene rin...
07/22/1980
4164504Steroidal[16଱,17-b]naphthaleno-21-carboxylic acid esters
Steroids having the formula ##STR1## wherein R1 is alkyl, aryl, or arylalkyl; R2 is hydrogen or halogen; R3 is hydrogen, methyl or fluorine; R4 is chlorine, fluorine or hydroxy and R5 is hydrogen...
08/14/1979
4160772Steroidal[16଱,17-d]cyclohexene-21-carboxylic acid esters
Steroids having the formula ##STR1## wherein R1 is alkyl, aryl or arylalkyl; R2 and R3 are the same or different and are hydrogen, alkyl or aryl; R4 is hydrogen and R5 is hydroxy or together R
07/10/1979
409103617-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 ଱, 17 ଱-b]naphthalenes and derivatives
pg,1 Steroids having the formula ##STR1## wherein X is ##STR2## R1 is alkyl, aryl or acyloxyalkyl; R2 and R3 are the same or different and are hydrogen, alkyl, alkoxy, carboalkoxy, formyl, ##STR3## hydr...
05/23/1978
4031075Alkylated pregnanes and process for obtaining same
The invention relates to novel 21-alkylated steroids of the pregnane series having the formula: ##STR1## WHEREIN X = H or halogen; Y = h2, h(oh), h(oacyl), O or H(halogen); R1 = an alkyl group having 1-4 C-atoms; R2 = r
06/21/1977
3994935Steroidal 16ଲ-alkyl[16଱,17-b]naphthalenes
Novel steroids having the structure ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is chlorine, fluorine, or hydroxy and R'1 is hydrogen or R1 and R'1 together are =O; R2 is hydrogen or ...
11/30/1976
39794171 H-androsta(16,17)cyclopentene-3-ones
Steroids having the formula ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is phenyl, naphthyl, or substituted phenyl or naphthyl, have useful anti-inflammatory activity....
09/07/1976
3944584Steroidal (16଱,17-d)cyclohexenes
A series of novel steroidal[ 16଱, 17-d]cyclohexenes having a 9-fluoro group is disclosed herein for use as anti-inflammatory agents....
03/16/1976
3937720Steroidal[16଱,17-ଲ]naphthalenes
Novel steroids having the structure ##SPC1## And the 1,2-dehydro derivatives thereof, wherein R1 is chlorine, fluorine, or hydroxy and R'1 is hydrogen or R1 and R'1 together are =0; R2 is hydrogen or ...
02/10/1976
 
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